ACS Applied Energy Materials
·
2023
·
IF 6.4
Bin Hu,Jiaqi Peng,Dongming Liu,Mingli Wu,Yuanyuan Wei,Bin Huang,Yanwei Li,Shunhua Xiao,Renheng Wang
High-nickel ternary material is one of the most promising cathode materials with high energy density. However, this material has the disadvantages of poor cycling stability, poor thermal stability, and low safety. The synergetic effect of single crystal, element doping, and surface coating is an effective way to improve its electrochemical performance. In this work, the particle size of the single-crystal LiNi0.83Co0.11Mn0.06O2 (NCM811) material was controlled by LiCl–KCl flux, and the internal/external synergy of Ti4+ doping and LiTi2O4 coating was realized by the pretreatment of Ti(OC4H9)4 and a subsequent new temperature-changing sintering process. The single-crystal structure greatly improved the crushing of material, the Ti4+ doping effectively broadened the lattice spacing and stabilized the layered structure, and the uniform LiTi2O4 coating effectively eliminated excess lithium salts and promoted the stability of the interface structure. The electrochemical test results showed that the modified materials had excellent electrochemical properties, especially a high lithium-ion diffusion rate and high cycle stability. Therefore, it will provide a solid technical support for the synthesis of high-performance single-crystal high-nickel ternary cathode materials.
研究领域:
材料科学
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电化学
·
能源存储
✓ 已验证
DOI
高影响因子
JOURNAL OF SEPARATION SCIENCE
·
2017
·Vol. 40
·期 10
·2278-2285
·
IF 2.557
Chen Xu,Yingjia Yu,Li Ling,Xueni Sun,Yan Li,Gengli Duan
In this paper, a facile extraction strategy is reported for the analysis of isopentenyl pyrophosphate, a key isoprenoid, based on magnetic core–shell microspheres with Ti 4+ ion exterior walls coupled with liquid chromatography and tandem mass spectrometry. Because of their excellent hydrophilicity and biological compatibility, the polydopamine@Fe 3 O 4 -Ti 4+ microspheres display ideal isopentenyl pyrophosphate extraction efficiency. The technique includes three steps: sample loading, nonphosphate washing, and phosphate elution. Moreover, the microspheres can be regenerated by thorough washing with a specific solvent and can be reused multiple times. The liquid chromatography with tandem mass spectrometry separation was performed on a Welch Ultimate® XB-C 18 column with a total chromatographic analysis time of 5 min; the analytical recovery was 98.52%. The proposed method was used to determine the isopentenyl pyrophosphate concentration in rat plasma samples collected from the Shanghai Chest Hospital. The results indicate the prospective value of the as-made microspheres for the sensitive and selective enrichment of phosphate compounds in complicated matrices.
研究领域:
分析化学
·
生物医学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF ALLOYS AND COMPOUNDS
·
2018
·
IF 3.779
Qiannan Wu,Dedong Meng,Yu Zhang,Qidong Zhao,QiJing Bu,Dejun Wang,Xiaoxin Zou,Yanhong Lin,Shuo Li,Tengfeng Xie
Acid-treatment has been proved to be an efficient approach to improve the photoelectrochemical (PEC) performance of hematite . However, efforts to optimize hematite photoanode have been limited by an inadequate understanding of the semiconductor surface . Here we make efforts to understand the microscopic charge separation processes of Ti 4+ doped Fe 2 O 3 photoanode before and after acid-treatment. Surface photovoltage (SPV) transient and the work function measurements directly reveal that acid-treatment leads to passivation of the surface states . Surface photovoltage (SPV) spectroscopic studies coupled to open-circuit photovoltage (OPV) measurements indicate that the surface states of hematite photoanode before acid-treatment result in the pinning of the Fermi level , which reduce the intensity of interfacial electric field at the semiconductor-electrolyte interface.
研究领域:
材料科学
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光电化学
·
能源材料
·
半导体物理
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表面科学
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太阳能转化
·
纳米材料
✓ 已验证
DOI
高影响因子
Journal of Advanced Ceramics
·
2022
·Vol. 11
·期 11
·1801-1814
·
IF 11.534
Cheng Fuhao,Zhang Fengnian,Liu Yufeng,Guo Meng,Cheng Chufei,Hou Jiadong,Miao Yang,Gao Feng,Wang Xiaomin
Environmental barrier coatings (EBCs) with excellent chemical resistance and good high-temperature stability are of great significance for their applications in next-generation turbine engines. In this work, a new type of high-entropy fluorite-structured oxide (Ce 0.2 Hf 0.2 Y 0.2 Pr 0.2 Gd 0.2 )O 2− δ (HEFO-1) with different Ti 4+ contents were successfully synthesized. Minor addition of Ti 4+ could be dissolved into a high-entropy lattice to maintain the structure stable, effectively reducing the phase formation temperature and promoting the shrinkage of bulk samples. Heat treatment experiments showed that all the samples remained a single phase after annealing at 1200–1600 °C for 6 h. In addition, high-entropy (Ce 0.2 Hf 0.2 Y 0.2 Pr 0.2 Gd 0.2 Ti 0.2 x )O 2− δ demonstrated great resistance to calcium—magnesium—alumina—silicate (CMAS) thermochemical corrosion. When the content of Ti was increased to x = 0.5, the average thickness of the reaction layer was about 10.5 after being corroded at 1300 °C for 10 h. This study reveals that high-entropy (Ce 0.2 Hf 0.2 Y 0.2 Pr 0.2 Gd 0.2 Ti 0.2 x )O 2− δ is expected to be a candidate for the next-generation EBC materials with graceful resistance to CMAS corrosion.
研究领域:
材料科学
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涂层
·
高温材料
·
腐蚀抗性
✓ 已验证
产品关联
DOI
高影响因子
MICROCHIMICA ACTA
·
2020
·Vol. 187
·期 9
·1-9
·
IF 6.232
Yin Zhenzhen,Cheng Xiaoli,Wang Gan,Chen Jia,Jin Yan,Tu Qiuyun,Xiang Juan
A highly sensitive and specific surface plasmon resonance (SPR) method using one anti-alpha-synuclein antibody (anti-αS) and titanium phosphate nanoparticles (Ti 4+ @TiP) was developed for quantitative evaluation of phosphorylated αS level which was defined by the ratio of p-αS to total alpha-synuclein (t-αS) (p-αS/t-αS). The close affinities of anti-αS to αS (0.975 pM −1 ) and p-αS (0.938 pM −1 ) were obtained. Based on this fact , both αS forms were simultaneously captured and the t-αS was quantified using the anti-αS immobilized Au chip. With the selective recognition of Ti 4+ @TiP nanoparticles, the p-αS was quantified. The dynamic ranges of our method were 1.0~20.0 pg mL −1 for the detection of t-αS and 0.1~10.0 pg mL −1 for that of p-αS. The analysis of αS- and p-αS-spiked artificial cerebrospinal fluid samples revealed the high accuracy of the method. Furthermore, the concentrations of αS and p-αS in clinical CSF samples collected from three healthy donors were determined and displayed a high correlation with the results from a commercial ELISA kit, confirming the viability and of the proposed method. The method is convenient, economical, and practical for the evaluation of phosphorylated αS level with high sensitivity and selectivity. It is of great significance for the early diagnosis of PD and the evaluation of PD progression. Graphical abstract
研究领域:
生物传感器
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纳米技术
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神经退行性疾病
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分析化学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
·
2024
·
IF 3.8
Chen Jiakai,Wang Danni,Wang Bing,Zhou Chengwei,Ding Chuan-Fan,Yan Yinghua
In the present study, click chemistry and Schiff base reactions were simultaneously applied to prepare polymer brush (PEG)–functionalized MOF materials (UiO-66-NH 2 ) and immobilized with Ti 4+ (MOF-Brush-THBA-Ti 4+ ) for phosphopeptide analysis. The material has a detection limit of 0.5 fmol, a selectivity of 2000:1, and a loading capacity of 133 mg/g for phosphopeptides. It also demonstrated great repeatability (10 cycles) and recovery rate (96.7 ± 1.4%). During the analysis of bio-samples, 4 specific phosphopeptides were identified in endogenous breast cancer serum, while 11 phosphopeptides were identified in skimmed milk. Moreover, 47 phosphopeptides correlated with 29 phosphorylated proteins were selectively identified from normal control serum, and 66 phosphopeptides correlated with 26 phosphorylated proteins were identified from breast cancer serum. Further analysis of gene ontology (GO) revealed that the detected phosphorylated proteins associated with breast cancer included positive regulation of receptor-mediated endocytosis, proteolysis, extracellular exosome, heparin binding, and chaperone binding. These findings suggest that these associated pathways might contribute to the etiology of breast cancer. Overall, this application exhibits enormous potential in the identification of phosphorylated peptides within bio-samples.
研究领域:
分析化学
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生物化学
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癌症生物学
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蛋白质组学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
MICROCHIMICA ACTA
·
2023
·Vol. 190
·期 10
·1-8
·
IF 5.7
Wang Bing,Zhang Xiaoya,Wang Baichun,Feng Quanshou,Luo Yiting,Wang Weimin,Ding Chuan-Fan,Yan Yinghua
A Ti 4+ functionalized β-cyclodextrin covalent organic framework nanoparticle (named as β-CD-COF@Ti 4+ ) was synthesized using a one-pot method successfully realizing the enrichment of phosphorylated peptides and exosomes based on the immobilized metal ion affinity chromatography strategy. The functionalized β-CD-COF@Ti 4+ exhibited superior performance on the enrichment of phosphopeptides, including high selectivity (1:1000), low detection limit (0.5 fmol), and loading capacity for phosphopeptides (100 mg·g −1 ). After treatment with β-CD-COF@Ti 4+ , 9 phosphopeptides from defatted milk, 29 phosphopeptides related to 23 phosphoproteins from normal group serum, and 24 phosphopeptides related to 22 phosphoproteins from the serum of uremia patients were captured. Through the analysis of Gene Ontology, the captured phosphoprotein is closely related to kidney disease, including lipoprotein metabolism, very-low-density lipoprotein particle, high-density lipoprotein particle, and lipid binding activity process. Furthermore, western blot verification showed that this nanoparticle could successfully capture exosomes from human serum. This study demonstrates great prospects for the enrichment of phosphopeptides and exosomes from actual bio-samples. Graphical Abstract
研究领域:
分析化学
·
生物化学
·
分子生物学
·
蛋白质组学
·
纳米技术
✓ 已验证
产品关联
DOI
PubMed
高影响因子
TALANTA
·
2017
·
IF 4.162
Jiebing Jiang,Xueni Sun,Yan Li,Chunhui Deng,Gengli Duan
Metal ions differed greatly in affinity towards phosphopeptides, and thus it is essential to systematically compare the phosphopeptides enrichment ability of different metal ions usually used in the IMAC techniques. In this work, for the first time, eight metal ions, including Nb 5+ , Ti 4+ , Zr 4+ , Ga 3+ , Y 3+ , In 3+ , Ce 4+ , Fe 3+ , were immobilized on the polydopamine (PDA)-coated Fe 3 O 4 (denoted as Fe 3 O 4 @PDA-M n+ ), and systematically compared by the real biosamples, in addition to standard phosphopeptides. Fe 3 O 4 microspheres were synthesized via the solvothermal reaction, followed by self-polymerization of dopamine on the surface. Then through taking advantage of the hydroxyl and amino group of PDA, the eight metal ions were easily adhered to the surface of Fe 3 O 4 @PDA. After characterization, the resultant Fe 3 O 4 @PDA-M n+ microspheres were applied to phosphopeptides enrichment based on the binding affinity between metal ions and phosphopeptides. According to the results, different metal ions presented diverse phosphopeptides enrichment efficiency in terms of selectivity, sensitivity and the enrichment ability from real complex samples, and Fe 3 O 4 @PDA-Nb 5+ and Fe 3 O 4 @PDA-Ti 4+ showed obvious advantages of the phosphopeptides enrichment effect after the comparison. This systematic comparison may provide certain reference for the use and development of IMAC materials in the future.
研究领域:
生物化学
·
分析化学
✓ 已验证
DOI
高影响因子
JOURNAL OF MATERIALS SCIENCE-MATERIALS IN ELECTRONICS
·
2023
·Vol. 34
·期 2
·1-10
·
IF 2.8
Guan Yeqing,Zhang Jinxian,Wang Fenglin,Li Wei,Mao Haijun,Liu Zhuofeng,Zhang Weijun,Chen Xingyu
The Ca 0.245 Li 0.325 Nd 0.395 Ti 1− x Sn x O 3 ( x = 0–0.12) ceramics were prepared by the traditional solid-state reaction method. The effects of Sn 4+ substitution for Ti 4+ on the phase composition, microstructure, and microwave dielectric properties of Ca 0.245 Li 0.325 Nd 0.395 Ti 1− x Sn x O 3 (CLNTS x ) were investigated in this work. The X-ray diffraction results showed that the ceramics had a single orthorhombic perovskite structure when x = 0–0.09. However, a secondary phase SnO 2 was observed with x > 0.09. The SEM micrographs indicated that the proper Sn 4+ substitution for Ti 4+ promoted the grain growth and homogenization. The analysis results of Raman spectroscopy revealed the correlation between vibration modes and microwave dielectric properties of CLNTS x ceramics with different Sn 4+ contents. The degree of cation order was related to the full width at half maximum (FWHM) of the Raman spectrum, and a lower FWHM value indicates higher cationic order and Q × f 0 value. The excellent microwave dielectric properties with ε r = 98, Q × f 0 = 3320 GHz, and τ f = 2.6 ppm/°C were obtained in the ceramics with x = 0.09 sintered at 1350 °C for 4 h.
研究领域:
材料科学
·
物理学
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF ALLOYS AND COMPOUNDS
·
2023
·
IF 6.2
Zhao Wang,Wenyue Zhao,Ze Li,Yazhou Peng,Chang Gao,Lei Shi,Wenjing Hua,Weidong Fei,Yu Zhao
The search for multiferroic materials with ferroelectric and ferromagnetic properties at room temperature continues to be driven by the prospect of new devices. In this paper, Ba 2+ -Ti 4+ co-doped Y 1- x (Ba 0.5 Ti 0.5 ) x FeO 3 were prepared by a traditional solid-state reaction method. The ferroelectricity and ferromagnetism of the co-doped ceramics have been enhanced simultaneously with the maximum polarization of 0.48 μC/cm 2 and the maximum magnetization of 3.25 emu/g, the switched charge density (0.26 μC/cm 2 ) measured by PUND tests indicating the intrinsic and switchable remanent polarization. The increase of Fe 2+ content (increased to 28 % with the increase of doping content) caused by Ba 2+ -Ti 4+ co-doping destroys the antiferromagnetic ground state, and the doping strategy enlarges the tilt angle of oxygen octahedron from 144.93° to 148.63°. The magnetic domain switches caused by the external electric field were directly observed by magnetic force microscopy, indicating the modulation of magnetic domain by polarization at room temperature. This work may provide useful information for the structural design and performance improvement of multiferroic materials.
研究领域:
材料科学
·
物理学
✓ 已验证
DOI
高影响因子
ACS Applied Materials & Interfaces
·
2024
·
IF 8.3
Yihan Tang,Shuaishuai Chen,Ming Wan,Hua Li,Qingliang You,Zhenlian Chen,Zhe Peng,Deyu Wang
Ni-rich layer-structured materials are some of the most promising cathodes owing to their attractive reversible capacity and cost-effectiveness. When the Ni content is increased to 90% and higher, mechanical deterioration becomes serious and leads to accelerated cyclic degradation, since removable Li+ is ∼0.85, accompanied by large lattice variation during operation. Here, we investigate the influences of Ti4+ bulky substitution, Nb5+ surface treatment, and their coutilization on the behavior of LiNi0.925Co0.065Mn0.01O2 (NCM92). In contrast to the limited positive effects of monousage, the coutilization of Ti4+ and Nb5+ obviously suppresses particles’ pulverization, relying on their synergistic effects of the shape of lattice variation and the protection of a tough shell layer. As a result, Ti & Nb-LiNi0.925Co0.065Mn0.01O2 (TiNb-NCM92) presents the best capacity retention, as high as 90.2% after 300 cycles, much higher than NCM92 (49.0%), Ti-NCM92 (76.3%), and Nb-NCM92 (72.4%). Our approaches demonstrate that the serious mechanical challenges of ultrahigh nickel cathodes could be alleviated by various remedies coutilized together.
研究领域:
材料科学
·
电化学
✓ 已验证
DOI
高影响因子
MICROCHIMICA ACTA
·
2021
·Vol. 188
·期 2
·1-11
·
IF 5.833
Liu Bin,Wang Baichun,Yan Yinghua,Tang Keqi,Ding Chuan-Fan
A strategy for effectively enriching global phosphopeptides was successfully developed by using ammonia methyl phosphate (APA) as a novel chelating ligand and Ti 4+ and Nb 5+ as double functional ions (referred to as Fe 3 O 4 @mSiO 2 @APA@Ti 4+ /Nb 5+ ). With the advantage of large specific surface area (151.1 m 2 /g), preeminent immobilized ability for metal ions (about 8% of total atoms), and unbiased enrichment towards phosphopeptides, Fe 3 O 4 @mSiO 2 @APA@Ti 4+ /Nb 5+ displays high selectivity (maximum mass ratio β-casein to BSA is 1:1500), low limit of detection (LOD, as low as 0.05 fmol), good relative standard deviation (RSD, lower than 7%), recovery rate of 87% ( 18 O isotope labeling method), outstanding phosphopeptide loading capacity (330 μg/mg), and at least five times re-use abilities. In the examination of the actual sample, 24 phosphopeptides were successfully detected in saliva and 4 phosphopeptides were also selectively extracted from human serum. All experiments have shown that Fe 3 O 4 @mSiO 2 @APA@Ti 4+ /Nb 5+ exhibits exciting potential in view of the challenge of low abundance of phosphopeptides.
Graphical abstract
研究领域:
生物化学
·
蛋白质组学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）