International Journal of Environmental Science and Technology
·
2023
·Vol. 20
·期 12
·13399-13410
·
IF 3.1
Xiong H.,Peng S.,Zhang B.
Nonionic surfactants with ideal surface properties and lower ecotoxicities have been highly attended in metal bioleaching and pollutant bio-treatment in environmental science field. In this study, both Acidithiobacillus ferrooxidans HX3 and Tween 80 (or Triton X-100) presence in cultures, bio-production and development of schwertmannite as a potential metal scavenger were investigated. To explore their correlations, the resulting ferric oxyhydroxides under various surfactant levels (lower/optimal/higher ones for Gp I/II/III treatments) were identified by many characterization methods. Result showed that after 48 h of normally bacterial reproduction, surfactant-rich cultures with Tween 80 more than 50 mg/L (25 mg/L for Triton X-100) could only achieve down 80% of ferrous oxidation percent and 10 7 cells/mL of cell numbers, while those with lower surfactant level were ahead 12 h. Culture pH values decreased to about 2.4 (or 2.0) from initially 2.8. All initial ferric oxyhydroxides were only pincushion-schwertmannite spheres. When cells sequentially reproduced within 36 h–48 h, presence of surfactants (except for Triton X-100 at 75 mg/L) could induce schwertmannite-pincushion assembling on developed spherical particles with a little of diamond-jarosite. And then during bacterial stability state (48 h–72 h), the pincushion assemblages on developed schwertmannite-spheres would disappear, following occurrence of more jarosite amount. Obviously, schwertmannite stability and morphological evolvement were affected by type and level of the added surfactants. These results will give a convincing proof for understanding biomineralization principles of iron minerals in natural environments with nonionic surfactants.
研究领域:
环境科学
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微生物学
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材料科学
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高影响因子
JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY
·
2023
·
IF 5
Ying Sun,Yongxiang Zhang,Xiaxia Liu,Yan Tingting,Liyan Shen,Dan Ye,Xia Kong,Yonghui Su,Qingping Tian
Transfersomes is one of the most effective nanotechnology-based formulation for transdermal delivery of minoxidil (MXD), however the potential use was limited by its low drug content ( DC ) and entrapment efficiency ( EE ). In this study, efforts have been made to improve DC and EE of MXD in transfersomes for effective topical treatment of alopecia . By dissolving both MXD and edge activator (Tween 80) in aqueous phase than either or both of them co-dissolving in organic solvent with lipids (phospholipid and cholesterol with mass ratio of 5:1), the DC and EE of MXD transfersomes prepared by thin film hydration method were significantly increased. The optimized transfersomes (MT) and its gel (MT gel ) with mass ratio of drug, Tween 80 and lipids 3:1:18 have a spherical morphology without aggregation, and a particle size of not more than 100 nm. The differential scanning calorimetry measurements revealed that the drug in MT was in the non-crystalline state. MT and MT gel exhibited better in vitro transdermal penetration ability and hair of C57BL/6 mice growth-promoting capacity than commercial formulations. MT gel has non-irritation and is better than MT in skin adhesion, stability, potential for skin storage and hair growth promotion ability, which could endow it to be a promising strategy for topical treatment of alopecia.
研究领域:
药剂学
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纳米技术
·
皮肤科学
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DOI
高影响因子
ENVIRONMENTAL SCIENCE & TECHNOLOGY
·
2026
·
IF 11.3
Jia Zhang,Shuang Zhang,Xinxin Xu,Hua Kuang,Chuanlai Xu,Xiaoling Wu
Inflammatory bowel disease (IBD) is a widespread public health problem worldwide, and environmental pollutants are regarded as the cause of IBD. Tween 80 (P80) may trigger IBD; however, its underlying mechanism of action has not been fully clarified, especially with respect to diet-induced susceptibility. This study systematically investigated the effect of P80 on the IBD development in male mice on a normal diet and high-fat diet (HFD) at an acceptable daily intake level. After 6 weeks of oral exposure to P80 (0.1, 1, 6%), the high-dose group of mice exhibited a significant increase in the disease activity index, a significant body weight loss, and a severe inflammatory response, with HFD markedly augmenting these effects. Multiomics results indicated that P80 exposure disrupted intestinal tryptophan metabolism and significantly reduced indole-3-acetic acid (IAA) levels. In vivo intestinal inflammation was transcriptionally regulated by genes related to the AhR/NF-κB/NLRP3 signaling pathway. Supplementing with IAA can improve inflammatory effects. In vitro studies confirmed that P80 exposure inhibited Lactobacillus from producing IAA, leading to an increase in the level of intestinal inflammation. This study revealed the specific toxic mechanism of P80-induced IBD and found that dietary factors have a synergistic toxic effect, providing new insights into the health risk assessment of environmental pollutants.
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PubMed
高影响因子
LANGMUIR
·
2020
·
IF 3.557
Mei Cui,Yuhao Duan,Yuanyuan Ma,Khaled W.A. Al-Shwafy,Yudong Liu,Xudong Zhao,Renliang Huang,Wei Qi,Zhimin He,Rongxin Su
Expansin has nonhydrolytic disruptive activity and synergistically acts with cellulases to enhance the hydrolysis of cellulose. The adsorption–desorption of expansin on noncellulosic lignin can greatly affect the action of expansin on lignocellulose. In this study, three lignins with different sources (kraft lignin (KL), sodium lignin sulfonate (SLS), and enzymatic hydrolysis lignin (EHL)) were selected as the substrates. The real-time adsorption–desorption of Bacillus subtilis expansin (BsEXLX1) on lignins was monitored using quartz crystal microgravimetry with dissipation (QCM-D). The effects of temperature and Tween 80 on the adsorption–desorption behaviors were also investigated. The results show that BsEXLX1 exhibited high binding ability on lignin and achieved maximum adsorption of 283.2, 273.8, and 266.9 ng cm–2 at 25 °C on KL, SLS, and EHL, respectively. The maximum adsorption decreased to 148.2–192.8 ng cm–2 when the temperature increased from 25 to 45 °C. Moreover, Tween 80 competitively bound to lignin and significantly prevented expansin adsorption. After irreversible adsorption of Tween 80, the maximum adsorption of BsEXLX1 greatly decreased to 33.3, 37.2, and 10.3 ng cm–2 at 25 °C on KL, SLS, and EHL, respectively. Finally, a kinetic model was developed to analyze the adsorption–desorption process of BsEXLX1. BsEXLX1 has a higher adsorption rate constant (kA) and a lower desorption rate constant (kD) on KL than on SLS and EHL. The findings of this study provide useful insights into the adsorption–desorption of expansin on lignin.
研究领域:
生物化学
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酶学
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材料科学
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DOI
PubMed
高影响因子
Canadian Journal of Chemistry
·
2022
·Vol. 101
·期 2
·
IF 1.051
Zhimei Wang,Yuehuan Zhang,Qing Chen,Xin Xiao,Carl Redshaw
This study has selected the medium-chain saturated fatty acid pelargonic acid as the raw material for the first time, and added the surface catalyst Tween 80 to the aqueous solution to form pelargonic acid–Tween 80 composite vesicles by a surface tension method. The compound vesicle was used to encapsulate five heterocyclic drugs (cefazolin sodium, chlorpromazine hydrochloride, gemcitabine hydrochloride, metronidazole, and isoniazid), all of which have disadvantages when used directly, and the effects of the vesicles on the five kinds of drugs were evaluated in terms of encapsulation rate and the in vitro sustained release in a simulated artificial intestinal fluid environment. The results revealed that the pelargonic acid–Tween 80 composite vesicles exhibit an encapsulation efficiency above 45%, and that the encapsulated drugs achieve a cumulative release effect of 6–10 h in a simulated artificial intestinal fluid environment, and the cumulative release rate is above 35%. This study proves that pelargonic acid–Tween 80 composite vesicles can be used as a carrier for encapsulated drugs, and this can extend the time of action of the drugs. This research illustrates the potential for application of pelargonic acid in the field of medicine.
研究领域:
药剂学
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生物医学工程
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材料科学
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DOI
高影响因子
JOURNAL OF MEMBRANE SCIENCE
·
2023
·
IF 9.5
Yajie Ding,Nianxiang Qiu,Jianqiang Wang,Zhe Yang,Fu Liu,Chuyang Y. Tang
Oil fouling is an inherent threaten of membrane-based separation of oil-water emulsion, while common physical sieving membrane separation and coalescence demulsification fail to achieve long term applications and combat severe water flux declines. We hereby report an “oil-water-receiving” membrane with anomalous wettability constructed by sub-10 nm Tween 80 assembly on hydrophobic PVDF nanofibers to establish independent water and oil transmembrane passageway. Water can go through the membrane freely along the hydrophilic nanofiber surface. While emulsified oils were diverted beneath the ultra-thin hydrophilic layer and captured by PVDF bulk to form coalesced oil phase and discharged out of the nanofibrous membrane as continuous macroscopic oil phase. The membrane showed stable permeate flux as high as 536 ± 40 L m −2 h −1 bar −1 after 10 h of continuously filtering oil-in-water emulsions. The conformation assembly of surfactants with hydrophilic and hydrophobic chains provides a new strategy to fabricate anti-fouling membranes for oil/water separation.
研究领域:
材料科学
·
环境工程
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DOI
高影响因子
Scientific Reports
·
2016
·Vol. 6
·期 1
·1-8
·
IF 5.228
Deng Ling-Li,Taxipalati Maierhaba,Que Fei,Zhang Hui
Attempts were made to solubilize thymol in Tween 80 micelle to study the solubilization mechanism of thymol and the effect of solubilization on its antioxidant activity. The maximum solubilized concentration of thymol in a 2.0% (w/v) Tween 80 micelle solution is 0.2 wt%. There was no significant difference in Z-average diameter between the empty micelles and thymol solubilized micelles. 1 H NMR spectra indicated that 3-H and 4-H on the benzene ring of thymol interacted with the ester group between the hydrophilic head group and the hydrophobic tail group of Tween 80 by Van der Waals’ force. Ferric reducing antioxidant potential (FRAP) and cupric ion reducing antioxidant capacity (CUPRAC) assays showed that the reducing antioxidant activity of free thymol did not change after solubilized in Tween 80 micelles. Compared to free thymol, the solubilized thymol showed higher activities to scavenge DPPH (2,2-diphenyl-1-picrylhydrazyl) and hydroxyl radicals. The present study suggested a possible preparation of thymol-carrying micelles with enhanced antioxidant activities that could be applied in food beverages.
研究领域:
食品科学
·
化学
·
生物化学
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DOI
PubMed
高影响因子
Nanoscience and Nanotechnology Letters
·
2017
·Vol. 9
·期 2
·123-133
·
IF 1.889
Sha Ruyi,Wu Yuanyuan,Cai Chenggang,Mao Jianwei,Liu Shiwang,Wang Wenxing
Garlic oil has been shown to have many pharmacological and biological activities. However, its poor solubility in water, volatility and instability limit its extensive application in the fields of medicine, cosmetics and food. In this work, nanoscale garlic oil microemulsions were prepared
with canola oil, a canola oil/garlic oil mixture or pure garlic oil as the oil phase, Tween-80 as the surfactant and ultrapure water as the aqueous phase, and the microemulsions were characterized. The influence of the co-surfactant type (glycerol, ethanol and n-butanol) and the mass
ratio of the surfactant to the co-surfactant (K
m) in the oil-in-water (O/W), water-in-oil (W/O), and binary continuous phase (BC) microemulsion regions in pseudoternary phase diagrams were investigated. Moreover, the antioxidant activity of the prepared garlic oil microemulsion
was evaluated. The results showed that when ethanol was used as a co-surfactant, a canola oil monophase microemulsion area of 42.03% can be obtained at a K
m of 2:1 with a particle size of 88.44 nm, and the monophase microemulsion area was approximately 18.55% and 52.54% for
the canola oil/garlic oil mixture as the oil phase at the mass ratios of 10:1 and 5:1, respectively, with a mean particle diameter of 13.33∼14.00 nm. The results also suggested that when using ethanol as the co-surfactant at a K
m of 3:1, the garlic oil monophase microemulsion
area of 52.54% and an O/W microemulsion area of 16.62% could be produced with a size of approximately 15.0 nm. Furthermore, the results showed that a microemulsion of garlic oil/Tween-80/ethanol/water exhibited remarkable antioxidant activity against the superoxide anion, hydroxide radical
and hydrogen peroxide using chemiluminescence methods, with IC50 values of 17.98 mg/mL, 4.17 mg/mL and 8.47 mg/mL, respectively. This study suggested that garlic oil microemulsions may be a promising dispersion for use in food and pharmaceutical products.
研究领域:
食品科学
·
药学
·
生物学
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DOI
高影响因子
Journal of Environmental Chemical Engineering
·
2023
·
IF 7.7
Shiyu Bao,Likun Zhao,Yuanwen Liu,Lewei Yang,Peng Liu,Chaoqi Chen,Xuhui Mao
Polycyclic aromatic hydrocarbons (PAHs) are a group of contaminants with low bioavailability and biodegradability . As a result, removing PAHs from contaminated soils is often inefficient. In this study, soils spiked with fluoranthene and pyrene were inoculated with Aeromonas sp. BCP-3, a newly isolated strain from coke-plant sludge , and treated in slurry bioreactors . The removal of PAHs was significantly affected by aeration rate, slurry water-soil mass ratio, stirring rate, temperature, and the concentration of Tween-80. Such effects were attributed to changes in BCP-3 growth, PAHs solid-liquid mass transfer, and slurry particle size. Notably, under optimal conditions (i.e., aeration rate of 1.5 L/min, temperature of 30 °C, stirring rate of 200 rpm, water-soil mass ratio of 1.5:1, and Tween-80 concentration of 1.3 %), 96.3 % and 97.2 % of initially spiked fluoranthene and pyrene were removed within 12 days, respectively. A PAH-contaminated soil was collected from a local coking plant and treated under the same conditions, except for the Tween-80 concentration. For the real soil, the Tween-80 concentration was 4 % to ensure a significant proportion of PAHs released into the liquid phase. Twenty-one days after inoculation of BCP-3, the removal efficiencies of low molecular weight PAHs and high molecular weight PAHs were 82.2 % and 51.8 %, respectively. The removal efficiencies of PAHs were significantly higher than the slurry without BCP-3 or HgCl 2 -sterilized slurry. BCP-3 improved the bioavailability and biodegradability of PAHs, resulting in effective PAH removal in slurry bioreactors . Overall, successful bioaugmentation was achieved with the addition of Tween-80 and the optimization of operating conditions.
研究领域:
环境科学
·
微生物学
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DOI
高影响因子
ENERGY & FUELS
·
2023
·
IF 5.3
Zhihui Ling,Shang Wang,Zhongzhan Leng,Chengmei Li,Wenhui Zhang,Xinxin Kang,Xianghui Qi,Cunsheng Zhang
To improve the performance of ethanol production from food waste, a consolidation process involving both the addition of surfactant and cell immobilization was investigated. Results showed that the optimum glucose concentration was 200 g/L for ethanol fermentation using Saccharomyces cerevisiae as inoculum. With the addition of 0.5% Tween 80, the ethanol production was improved from 68.1 to 79.8 g/L, which was attributed to the increased mass transfer of cells provoked by Tween 80. In a cell-immobilized system, wheat straw was used as the matrix to carry the cells. A high ethanol production of 87.8 g/L was obtained with the sequential fermentation mode due to the high cell density on the cell carrier. The results of a mass balance calculation revealed that the ethanol production of food waste achieved 340.4 kg/t (on a dry basis), which provided an insight that food waste was a suitable substrate for ethanol production. The main cost was spent on energy consumption in the processes of food waste sterilization, hydrolysis, fermentation, and ethanol distillation, and measures for reducing the energy were suggested to improve the economic performance of ethanol production.
研究领域:
生物技术
·
环境科学
·
发酵工程
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高影响因子
Scientific Reports
·
2021
·Vol. 11
·期 1
·1-11
·
IF 4.38
Yang Zuoyi,Mao Xingchen,Cui Jiahao,Wang Yujie,Zhang Yaping
This study examines the specific effect of Tween 80 on the conversion of anthracene (ANT) in laccase medium system regarding surfactant chemical changes and mechanism. The conversion rate and degradation products of ANT were investigated in different concentrations of Tween 80 solution. Between Tween 80 concentration 0–40 critical micelle concentrations (CMC), the kinetic parameter-k (h −1 ) and corresponding half-life T 1/2 decreased with increasing concentration. When Tween 80 was above 20 CMC the laccase-medium system converted > 95% of ANT to anthraquinone within 12 h. During the entire enzymatic reaction, the laccase activity in the system increased with increasing Tween 80 concentration. Combined with GC/MS analysis of the product, it was speculated that hydrogens belonging to the ether-oxygen bond and carbon–carbon double bond α-CH of Tween 80, were removed by the laccase-media system, promoting its degradation. Additionally, enhanced activity caused by oxygen free radicals (ROS) such as RO• and ROO•, continuously oxidized Tween 80, which in turn produced free radicals while converting ANT. This study provides new theoretical support toward the application of surfactants in the elimination of polycyclic aromatic hydrocarbons.
研究领域:
环境科学
·
生物化学
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DOI
PubMed
高影响因子
JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE
·
2022
·Vol. 34
·期 1
·1-15
·
IF 4.727
Wu Chuang,Wang Haixiang,Cao Jin
Electrospinning is a promising technique for preparing bioartificial blood vessels. Nanofibers prepared by electrospinning can simulate the structure of extracellular matrix to promote cell adhesion and proliferation. However, thorn-like protrusions can appear as defects on electrospun scaffolds and coaxial electrospun nanofibers often have no clear core/shell structure, which can seriously affect the quality of bioartificial blood vessels. To address these problems, Tween 80 is added to the electrospinning solution, which results in a stable Taylor cone, eliminates the thorn-like protrusions on electrospun bioartificial blood vessels, and reduces interfacial effects due to different core/shell solutions during coaxial electrospinning. Simulations, biomechanical tests, and in vivo studies were performed. The results demonstrate the excellent mechanical properties and biocompatibility of the bioartificial blood vessel. This research provides a useful reference for optimizing the electrospinning process for fabricating bioartificial blood vessels. Graphical Abstract
研究领域:
组织工程学
·
生物材料科学
·
生物医学工程
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PubMed
高影响因子
危险品化学品经营许可证（带存储）