JOURNAL OF MATERIALS SCIENCE
·
2025
·
IF 3.9
Yang Na,Wang Zihan,Liu Ze,Tian Huafeng,Gao Dahai,Guo Gaiping,Dai Yuhua
As a hydrophobic natural protein, zein has attracted extensive attention because of its versatility and excellent biodegradability. However, neat zein exhibits poor spinnability during electrospinning. To fabricate zein-based nanofibers, different hydrophilic co-spinning agents (collagen (Co), gelatin (GE) and polyethylene oxide (PEO)) were incorporated and optimized electrospinning parameter (voltage) for each additive was reported. The relationship between the performance of spinning solution as well as the spinnability and microstructure of zein nanofabrics was analyzed in detail. Co-spinning could improve the spinning ability of zein. The morphology of nanofibers was improved to varying degrees by adjusting the content of co-electrospinning agents and adjusting process parameters. The viscosity, conductivity and the pH value of the spinning solution with different co-spinning agents were analyzed. PEO exhibited a more dramatically effect on improving the spinning ability of zein. The zein-based film had a uniform and complete structure and certain hydrophobicity, and exhibited wide application prospects.
研究领域:
材料科学
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生物材料
✓ 已验证
产品关联
DOI
高影响因子
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2025
·
IF 8.5
Junbo He,Hong Tang,Ruifeng Liao,Hong Lin,Weinong Zhang
To enhance the physicochemical properties of zein nanoparticles, zein complexes with two Gemini surfactants ( 12–3-12 and 12–4-12 ) were prepared using the anti-solvent method and investigated the physicochemical properties, formation mechanism and antibacterial activity. Results indicated that the optimal mass ratio between zein and Gemini surfactants was at 1:1, and the incorporation of Gemini surfactants significantly improved the surface properties of zein, reducing its surface hydrophobicity and surface tension, thereby enhancing its dispersion in aqueous media. Fluorescence spectroscopy and molecular docking experiments further elucidated the interaction mechanisms between zein and Gemini surfactant, revealing a spontaneous binding process, mainly driven by hydrophobic and hydrogen interaction, and a strong binding affinity of 12–4-12 with zein. Additionally, the zein/Gemini surfactant complexes exhibited significant antibacterial activity against Staphylococcus aureus , with the zein/ 12–4-12 complex showing particularly prominent inhibitory effects. Therefore, this research not only provides a theoretical foundation for the construction of Gemini surfactant stabilized zein nanoparticles but also points the way for the subsequent embedding of bacteriostatic agents to achieve synergistic antibacterial effects.
研究领域:
食品科学
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材料科学
·
微生物学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2020
·
IF 5.162
Xiaoxiao Sun,Chuqiao Pan,Zhuoyang Ying,Dongyan Yu,Xitai Duan,Fangfang Huang,Junhong Ling,Xiao-kun Ouyang
We aimed to develop a stable nanosystem with k -carrageenan (Kc), an anionic polysaccharide , combined with tween 80 to stabilize zein nanoparticles. The experimental results showed that the particle size, zeta-potential, and stability of the system depend on the Kc amount when the zein amount was unchanged. We found that the nanosystem with 5.0 and 10.0 mg Kc had a smaller particle size (250.1 ± 0.9 and 287.6 ± 1.4 nm, respectively), low polydispersity index (PDI, ≤ 0.20), and high stability when the external conditions changed. No obvious flocculation or deposition was observed at pH of 3–9, salt ion concentrations of 0–500 mmol/L, temperature of 30 °C and 50 °C–90 °C, and storage at 4 °C for 30 days. When the Kc-ZNP system was loaded with curcumin (Cur), there was a good encapsulation effect (5.0 mg Kc with 1.00 mg Cur (EE (%) = 34.69% ± 2.02%, size = 380.23 ± 5.80 nm, PDI = 0.252 ± 0.018) and 10.0 mg Kc with 2.00 mg Cur (EE (%) = 20.13% ± 1.05%, size = 431.27 ± 0.78 nm, PDI = 0.269 ± 0.020), ensuring that the particle size was not too large. Therefore, Kc–ZNPs could be a potential delivery system for fat-soluble drugs.
研究领域:
食品科学
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药物递送系统
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生物材料
✓ 已验证
DOI
高影响因子
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
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2020
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IF 4.192
Shuangshuang Huang,Junbo He,Lijuan Han,Hong Lin,Gang Liu,Weinong Zhang
To increase the water solubility of zein as a stabilizing agent for oil-in-water (O/W) emulsions, three zein-polyglycerol (Zein-PG) conjugates, Zein-PG-2, Zein-PG-6, and Zein-PG-10, were prepared by dehydration between zein and polyglycerol aldehydes obtained by NaIO4 oxidation of polyglycerol-2, -6, and -10 and characterized by free amine content, grafting degree, Fourier transform infrared spectroscopy, and fluorescence spectra. All conjugates dispersed in water as nanoparticles were verified by transmission electron microscopy. Conjugation with PG changed the isoelectric point of zein from 6.2 to 6.8 and to 4.0. Zein-PG-6 and Zein-PG-10 showed strong stabilization on the O/W emulsions with 18-fold loading of soybean oil on the basis of conjugate mass, displaying high oil loading capacity. Confocal laser scanning microscopy (CLSM) confirmed the O/W structure of emulsions and that the absorption of Zein-PG-10 on the oil droplet surface offered the driving force to be stable. The present Zein-PG conjugates thus produced an enticing resource for use as nanocarriers or bioemulsifiers in food or pharmaceutical industries.
研究领域:
食品科学
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生物材料学
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制药工程
✓ 已验证
DOI
高影响因子
WATER AND ENVIRONMENT JOURNAL
·
2022
·Vol. 36
·期 4
·704-712
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IF 1.977
Xiaoqing Liu,Peng Huang,Jianfeng Wang,Yufeng He,Pengfei Song,Rongmin Wang
In order to effectively promote the treatment of pollution containing organics or crude oil, many oil-absorbing materials were explored. However, most of them were synthetic polymers, which was difficult to be decomposed and easily cause secondary pollution. In this study, zein and sodium alginate (SA), two cheap natural polymer materials, were used as eco-friendly and biodegradable biomass materials; a novel porous biomass-based sponge (ZS-PBSp) was synthesized. Then, by impregnating with SiO 2 nanoparticle (nano-SiO 2 ) and octadecanethiol (OCT), the modified porous sponge (ZSSiOsp) was obtained. ZSSiOsp was characterized by scanning electron microscopy (SEM), infrared (IR), X-ray diffraction (XRD) and thermogravimetric analysis (TGA) and applied to adsorb organics, such as organic solvents, petroleum products and cooking oil. It indicated that the surface of ZSSiOsp was rough, and its water contact angle (WCA) increased to 131.5°. ZSSiOsp effectively adsorbed organics, its absorption capacity got to 115.7% for chloroform and 77.6% for rapeseed oil, respectively. It also effectively separated oily substances from oil–water mixture. In summary, the obtained ZSSiOsp was an eco-friendly material for oil absorption and separation, which was a kind of promising candidate in water treatment and environmental protection.
研究领域:
环境科学
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材料科学
✓ 已验证
产品关联
DOI
高影响因子
FOOD CONTROL
·
2024
·
IF 5.6
Jinman He,Gulden Goksen,Xinli Cong,Mohammad Rizwan Khan,Naushad Ahmad,Wanli Zhang
This study aims to develop zein co-encapsulated Wampee [ Clausena lansium (Lour.) Skeels] essential oil (WEO) and propolis ethanol extract (PEE) for incorporation into sodium alginate matrix (ZPWS). The films were evaluated for their morphological features, chemical structure, mechanical and barrier properties, as well as their resistance to high temperatures. Additionally, antibacterial effects and antioxidant activities of films were investigated. The functional properties of zein were also evaluated for its ability to effectively co-encapsulate WEO and PEE, achieving in delayed release. Overall, the ZPWS films exhibited excellent functional properties compared the original films. These enhancements included greater tensile strength, increased rigidity, heightened resistance to water, improved thermal stability, a more condensed structure, and the presence of strong antioxidant and long-lasting bacteriostatic properties. Finally, a real-time study on the edible coated films was carried out strawberries preservation. The ZPWS film demonstrated good potential for application in food preservation.
研究领域:
食品科学
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材料科学
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生物学
✓ 已验证
产品关联
DOI
高影响因子
ACS Omega
·
2022
·
IF 4.132
Xiang Li,Yupeng Wang,Qiankun Shi,Nuo Zhen,Jin Xue,Jingsheng Liu,Dongfang Zhou,Hao Zhang
Current cancer treatment is not only limited to monotherapy but is also influenced by limited drug delivery options. Combined chemokinetic-photokinetic therapy has great promise in enhancing anticancer effects. Meanwhile, zein has superior self-assembly properties and can be loaded with photosensitizers. Herein, the targeted multifunctional nanoparticles based on zein/hyaluronate acid (HA)/tannin (TA)/Cu2+ loaded with IR780 (ZHTC@IR780) are constructed for synergetic cancer therapy by chemo-dynamic therapy (CDT) and photodynamic therapy (PDT). There is experimental proof that ZHTC@IR780 nanoparticles (NPs) can relieve the tumor hypoxic microenvironment by catalytic decomposition of endogenous H2O2 to O2 and further react with O2 to produce toxic 1O2 with 808 nm laser irradiation. The glutathione oxidase-like effects of ZHTC@IR780 NPs can generate Fenton-like Cu+ ions and deplete GSH for efficient hydroxyl radical (•OH) production. In addition, CDT combined with PDT enhances the antitumor effect. Photodynamic therapy can cause immunogenic cell death, increase calreticulin eversion, release histone with high mobility, and promote apoptosis of tumor cells.
研究领域:
生物医学工程
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肿瘤治疗学
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纳米医学
✓ 已验证
DOI
PubMed
高影响因子
Food Packaging and Shelf Life
·
2019
·
IF 3.63
Ping Shao,Yong Liu,Christos Ritzoulis,Ben Niu
This work studied the effect of nonionic surfactant (Tween 80), anionic surfactants sodium dodecyl sulfate (SDS), cationic surfactants sodium cetyltrimethyl ammonium bromide (CTAB), amphoteric surfactant (Lecithin) on the characteristics of electrospun zein nanofibers and on the release of cinnamaldehyde essential oil (CEO) in zein nanofibers. The effect of applying nanofibers as an antibacterial package was also investigated. Scanning electron micrographs demonstrated that the flat shape of zein nanofibers could shift to round when surfactants were added. The interaction between zein and lecithin caused many granules while the addition of other surfactants produced a smooth surface. Fourier transform infrared indicated that the addition of surfactants could change the secondary structure of zein. The addition of CTAB to zein nanofibers decreased the release of CEO while addition of Tween80, lecithin and SDS accelerated release in ethanol aqueous solution. The nanofibers inhibited the growth of microorganisms and prolonged the shelf life of mushrooms, which confirmed that it can be applied in active antibacterial package.
研究领域:
食品科学
·
材料科学
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF MOLECULAR LIQUIDS
·
2021
·
IF 6.165
Fangyuan Jiang,Lianlian Yang,Songyan Wang,Xiaoguo Ying,Junhong Ling,Xiao–kun Ouyang
In this study, zein was stabilized using alginate oligosaccharides (AOS) for the delivery of curcumin (Cur) through antisolvent precipitation. Zein-AOS 2:1 nanoparticles were uniform and stable (size 116.5 nm, polydispersity index (PDI) 0.16, charge −30 mV). The complex nanoparticle system was relatively stable under different conditions, including pH 4–9 and temperature 30–90 °C. In addition, the encapsulation efficiency of the Cur/zein-AOS 2:1 complex nanoparticles was 89.7%. Zein was protected during gastrointestinal digestion. Only 32.9% Cur was released in the stomach after 90 min and 83.8% was released in the intestinal tract after 240 min proving that zein-AOS complex nanoparticles showed a good sustained-release effect. Thus, the zein-AOS complex nanoparticle system is suitable for delivering encapsulated lipophilic bioactive compounds.
研究领域:
食品科学
·
生物材料学
✓ 已验证
产品关联
DOI
高影响因子
LWT-FOOD SCIENCE AND TECHNOLOGY
·
2021
·
IF 4.952
Yuxuan Liu,Qiufang Liang,Xueqiong Liu,Husnain Raza,Haile Ma,Xiaofeng Ren
The study was conducted to understand the effect of zein-gum Arabic (GA) complex coacervates prepared by ultrasound treatment on the encapsulation of resveratrol. Compared with zein, zein-GA complex coacervation largely increased the encapsulation efficiency from 26.19% to 55.85% and it was further increased to 74.2% after sonication. Also, prominent rise in the related loading capacities from 2.79% to 6.01% was noted. The increased particle size by the addition of GA and polydispersity index of the ternary complex was dramatically reduced after ultrasound treatment; the absolute values of zeta potential were increased. The hydrogen bonds, electrostatic interactions and hydrophobic effects were the main driving forces for the formation of the ternary complex particles. Ultrasound treatment strengthened the hydrogen bonding and electrostatic interactions, resulting in the formation of compact and homogeneous composite nanoparticles with smaller particle size, which was further confirmed by scanning electron microscope and atomic force microscope. These findings reveal the mechanism of ultrasound enhancing the zein-GA complex coacervation to load resveratrol, and demonstrate its promising effect in modifying protein-polysaccharide complex coacervation as a delivery carrier in the functional food and beverage industry.
研究领域:
食品科学
·
生物化学
✓ 已验证
DOI
高影响因子
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2022
·
IF 8.025
Jing Hu,Zhenjun Xiong,Yuqing Liu,Jinyou Lin
Conventional petroleum-based synthetic polymeric fiber filter materials for separation may cause secondary pollution to the environment due to their non-degradable properties. Herein, we report a facile method of preparation of a biodegradable composite filter that can achieve filtration for air by underlaying the commercialized cellulose paper towel under electrospun zein fibers. The morphology of zein fibers was successfully steered via varying the weight ratios of ethanol/deionized water mixture solvent, as a result, the round or flat ribbon fibers were obtained. The effect of zein fiber morphology on air filtration performance was investigated both experimentally and theoretically. It was found that the flat ribbon fiber filter had a higher filtration efficiency (99%) for PM0.3 removal and a lower pressure drop (109 Pa) compared with the round zein fiber filter. Notably, the as-prepared composite filter can be biodegradable easily, contributing to green ecological environment. This work shows an efficient way to develop biodegradable filtration materials with the cheap price, easy availability of component materials, exhibiting a great potential application in air filtration area.
研究领域:
材料科学
·
环境科学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2024
·
IF 7.7
Naiteng Wei,Feng Yang,Yaxin Zhao,Huafeng Tian,Yujuan Jin,Rakesh Kumar
Due to people's environmental awareness and the continuous improvement of the living environment requirements, the pollution problem of fine particles has attracted widespread attention and great importance. Therefore, the development of new green and environmentally friendly air filtration materials with high efficiency and low resistance is ongoing. In this work, eco-friendly zein/ethylcellulose blende nanofiber membranes with different fiber morphologies, diameter sizes, and hydrophobicity are prepared by electrospinning technology, and their performance in the field of air filtration and purification is investigated, to make them highly efficient for the adsorption of small pollutants of various polarities. The experiments showed that the hydrophobicity of the nanofiber membrane was adjusted by changing the ratio of zein and ethylcellulose, and the addition of ethylcellulose improved the thermal stability and use temperature of the composite nanofiber membrane. The filtration efficiency of the nanofiber membrane can reach more than 85 % for small particle pollutants of different polarities, and both sides of the tested membrane have high filtration capacity, which can still be maintained after three times of reused. This gives it great potential and broad application prospects in the field of air filtration.
研究领域:
材料科学
·
环境科学
·
生物工程
✓ 已验证
产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）