Journal of Environmental Chemical Engineering
·
2026
·Vol. 14
·期 3
·122290
·
IF 7.5
Shujuan Yang,Mengyu Ren,Donghui Li,Yong Zhang,Haichuan Zhang
The development of ultrafiltration membranes with integral sponge-like structures is essential for efficient dyes and salts removal from textile wastewater. However, enhancing antifouling performance while controlling the formation of full sponge-like structures remains challenging. In this study, an amphiphilic copolymer (PVP-PS) was successfully polymerized and blended with PES via a single step phase inversion process, using N -vinylpyrrolidone (NVP) and styrene (St) as additives. Unlike single-monomer modifications that suffer from poor modifier retention or limited structural tunability, this dual-monomer strategy precisely regulates the hydrophilic-hydrophobic balance. By optimizing the ratio of hydrophilic/hydrophobic monomers, an entirely spongy-like membrane morphology was achieved. Scanning electron microscopy (SEM) confirmed the formation of the pore structure, while Fourier transform infrared spectroscopy (FTIR) verified the successful incorporation of the PVP-PS copolymer. The optimized membrane, designated S-M0.5, exhibited a water flux of 711.5 L‧m −2 ‧h −1 and excellent antifouling performance with a FRR exceeding 90%. When applied to separate a dye/salt mixture containing 2.5 g‧L −1 Na 2 SO 4 and 200 ppm Congo red (CR) at 1 bar, S-M0.5 achieved a high CR rejection rate of 98.38% alongside a low Na 2 SO 4 rejection rate of 9.86%, and a stable dye solution permeability of 83.6 L‧m −2 ·h −1 . These results highlight the potential of the developed membrane for practical textile wastewater treatment.
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Polymer Chemistry
·
2013
·Vol. 4
·期 16
·4442-4449
·
IF 5.231
Tao Xing,Xianzhu Yang,Liyi Fu,Lifeng Yan
Glycopolymer with near infrared fluorescence (NIRF glycopolymer) has been designed and synthesized. The NIRF glycopolymer was prepared by firstly employing a combination of ring opening polymerization and Reversible Addition–Fragmentation Chain Transfer (RAFT) polymerization, followed by post-functionalization with an aminocyanine molecule. The obtained NIRF glycopolymer was characterized by nuclear magnetic resonance (NMR), gel permeation chromatography (GPC), and UV-vis and fluorescence spectrophotometry. The as-prepared copolymer is a potential drug delivery system with a bioimaging probe in the NIR region for tracing the biodistribution of the polymer in cells or the body. The bioactivity of the obtained material was evaluated by incubating the material with HepG2 cells, and the result shows an enhanced and fast endocytosis due to the specific interaction between the HepG2 cells and NIRF glycopolymer, and the process can be traced by fluorescence microscopy.
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Petroleum Science
·
2025
·
IF 6.1
Kai-He Lv,Qiang Li,Li-Li Yan,Yong Kong,Zhang-Cheng Yang,Yuan-Zhi Qu,Ren Wang,Jin-Sheng Sun,Jian Li
Solid-free brine completion fluids, characterized by their exceptional reservoir protection capabilities and optimal rheological behavior, are highly desirable for applications in oil and gas reservoirs and have attracted significant attention in recent decades. However, as the core component of completion fluids, the viscosifier was prone to curling or even precipitating in high-temperature, high-density inorganic salt (divalent calcium) environments, leading to failure in thickening performance. In this study, a micro-crosslinked amphoteric viscosifier (i.e., A-DDAS) resistant to high temperature and calcium ions was synthesized via free radical copolymerization of N,N-dimethylacrylamide (DMAA), diallyl dimethyl ammonium chloride solution (DMDAAC), 2-acrylamido-2-methylpropane sulfonic acid (AMPS), [2-(Methacryloyloxy) ethyl] dimethyl-(3-sulfopropyl) ammonium hydroxide (SBMA), and pentaerythritol triallyl ether (APE). The molecular structure and physicochemical properties of the copolymer were systematically studied by NMR, FTIR, XPS, TGA and XRD. Rheological experiments demonstrated that calcium bromide brine containing A-DDAS copolymers exhibited outstanding shear-thinning behavior and rapid thixotropic recovery, essential for efficient wellbore cleaning and fluid displacement during completion operations. As the density of calcium bromide brine increased, more calcium ions shield electrostatic attractions between the cationic and anionic moieties along the copolymer backbone, thereby promoting full extension of the polymer chains and enhancing the binding energy with water molecules. After adding 1.0 wt% A-DDAS copolymer to a 1.75 g/cm 3 calcium bromide brine and aging the mixture at 180 °C for 16 h, the completion fluids exhibited an apparent viscosity of 71 mPa·s, plastic viscosity of 64 mPa·s, and yield point of 7 Pa, which were significantly better than common viscosifiers (HE300 and Dristemp). Therefore, A-DDAS copolymers demonstrated exceptional thickening capacity and dynamic shear enhancement in high-temperature, high-density calcium bromide brine, notably rendering it ideally suited for deployment in completion fluids for deep and ultra-deep wells.
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Journal of Biomedical Nanotechnology
·
2014
·Vol. 10
·期 2
·324-335
·
IF 7.578
Lv Li,Shen Yuanyuan,Li Min,Xu Xiaofen,Li Mingna,Guo Shengrong,Huang Shengtang
Novel poly(anhydride-ester)-b-poly(ethylene glycol) copolymers (PAE-b-PEGs) were synthesized by esterization of methyl poly(ethylene glycol) and poly(anhydride-ester), which were obtained by the melt polycondensation of α, ω- acetic anhydride-terminated poly(L-lactic
acid), and characterized by 1H-NMR and gel permeation chromatography. The two poly(anhydride-ester)-b-poly(ethylene glycols) (denoted as PAE-b-PEG2k and PAE-b-PEG5k) thus obtained can selfassemble in water to form micelles with hydrodynamic
diameters of 92.5 and 97.5 nm above their critical micelle concentrations of 3.78 and 2.36 μg/mL, respectively. The curcumin-loaded PAE-b-PEG2k and PAE-b-PEG5k micelles were prepared by the solid dispersion method, and they could encapsulate approximately
7% (w/w) curcumin. The diameters of the micelles were stable for 5 days. Curcumin is released faster from the micelles at pH 5.0 than at pH 7.4. Curcumin is released from the micelles at a fast rate during the initial 12 h, followed by a zero-order release during the subsequent 200 h, both
at pH 5.0 and 7.4. The IC50 values of the curcumin-loaded PAE-b-PEG2k and PAE-b-PEG5k micelles against HeLa cells are 12.41 and 15.31 μg/mL, respectively, which is lower than that of free curcumin (25.90 μg/mL). The PAE-bPEG2k
micelles are taken up faster than the PAE-b-PEG5k micelles by HeLa cells. Curcumin-loaded micelles can induce G2/M phase cell cycle arrest and apoptosis of HeLa cells.
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MOLECULES
·
2022
·Vol. 27
·期 16
·5059
·
IF 4.927
Xiaohan Liao,Kai Niu,Feng Liu,Yongming Zhang
In recent years, polymers with stimuli-responsive properties have been increasingly reported on due to their diverse applications. However, most of the studies have only focused on the performance of polymers under specific scenarios. The laws of changes in the properties in response to various external stimuli have been less systematically and quantitatively studied. In this paper, we prepared an amphiphilic polymer (PadaMX and PAdaM3QA−X) with temperature-, pH-, ion-, and β-cyclodextrin (β-CD)-responsive properties. According to the cloud point tested by the UV-Vis method, the lower critical soluble temperature (LCST) of PAdaM3QA−10% was more sensitive to a change in pH and less sensitive to a change in ions compared with PadaM3 due to quaternized side chains with a stronger intramolecular mutual repulsion. We then fabricated the coatings with responsive properties by immobilizing the adamantyl groups on β-CD-modified surfaces. The hydrophilicity of the coatings was improved after quaternization, as proven by the water contact angle (WCA) measurement. The antifouling and antibacterial performance was further evaluated via the fluorescence intensity of bovine serum albumin (BSA) adsorbed on the surfaces and the spread plate method. A 78.4% BSA desorption rate and a 96.8% sterilization rate were achieved by the PAdaM3QA−10% coating. In summary, this work prepared a multiple-stimuli-responsive amphiphilic copolymer for antifouling and antibacterial functionality via a “resistance–kill–release” mechanism.Keywords:stimuli-responsive;amphiphilic polymers;host–guest interactions;antifouling;antibacterial
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JOURNAL OF COLLOID AND INTERFACE SCIENCE
·
2022
·
IF 9.965
Ying Li,Quan Qi,Shengdao Shan,Zhikan Yao,Fu Liu,Baoku Zhu
In this study, a blend membrane consisting of polyvinylidene fluoride (PVDF) and tertiary amine containing random copolymer poly(methyl methacrylate-r-dimethylamino-2-ethyl methacrylate) (P(MMA- r -DMAEMA)) was fabricated and utilized as an adsorptive membrane for micropollutants (anionic dye and heavy metal ions) removal from aqueous solutions. Cross-linking the random copolymer by p-xylylene dichloride (XDC) produced the membrane with improved copolymer retention ratio and stability, while slightly variated physicochemical properties. Besides, the fluxes of crosslinked blend membranes dramatically increased from 0.7 ± 0.1 L/(m 2 h) to 118.6 ± 5.9 L/(m 2 h). Then the present blend membrane was carried out adsorption and filtration experiments to investigate the influence of various of operation parameters including initial solution pH value, contacting time, initial solution concentration, and recycling efficiency on micropollutants removal. The experimental results showed that the removal of the anionic dyes and heavy metal ions on this tertiary amine containing blend membrane was a pH-dependent process with the maximum adsorption capacity at the initial solution pH of 3.5 for anionic dyes and 6.0 for metal ions, respectively. The membrane showed highly efficient capture of sunset yellow (above 99%). Meanwhile, the captured sunset yellow was recovered and concentrated with a small volume of alkaline solutions at pH 10.0, which simultaneously regenerated the membrane for its reuse. In a 3-cycle capture-recovery test, the membrane demonstrated a high sunset yellow recovery ratio and a volumetric concentration ratio as high as 400%. Our study provides an alternative strategy for functionalized membrane fabrication, micropollutants removal and recovery.
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COLLOIDS AND SURFACES B-BIOINTERFACES
·
2014
·
IF 4.287
Chunhua Gu,Vanminh Le,Meidong Lang,Jianwen Liu
Biodegradable graft copolymer, chitosan- graft -poly( ɛ -caprolactone) (CS- g -PCL) was synthesized via ring opening polymerization and characterized by 1 H NMR and FTIR spectroscopy. Then graft copolymers were self-assembled into micelles as drug delivery system. To evaluate drug-polymer compatibility, the Flory–Huggins interaction parameter between 5-fluorouraci (5-Fu) and hydrophobic segment was calculated. The result was in agreement with experimental data from drug loading content and drug loading efficiency. Meanwhile, DLS and TEM were utilized to evaluate the trend of particle size and morphology in aqueous solution with different repeating units of ɛ -CL. The in vitro drug release data was fitted with three kinetic models, usually applied in the drug delivery system. Results indicated that the release of 5-Fu was controllable and the release half-time could reach as long as 54.46 h, much slower than that of free 5-Fu. Cytotoxicity evaluation and cellular apoptosis study suggested good biocompatibility of CS- g -PCL micelles. Moreover, 5-Fu loaded micelles could delay the release of drug and exert comparable cytotoxicity against A549 cells.
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RSC Advances
·
2015
·Vol. 5
·期 16
·12329-12337
·
IF 3.84
Hai-Xia Wu,Lei Tan,Mei-Yan Yang,Chuan-Jun Liu,Ren-Xi Zhuo
A series of random copolymer brushes of acrylamide (AM) and 2-(perfluorinated hexyl)ethyl methacrylate (FMA) were grafted from initiator-functionalized silicon wafers by surface-initiated atom transfer radical polymerization. The water contact angle, X-ray photoelectron spectroscopy and atomic force microscopy were used to characterize surface wettability, surface composition, and morphology of the surfaces modified with polymer brushes, respectively. The protein-resistance performance of the surfaces grafted with polymer brushes was evaluated using micro-BCA protein assay reagent. It was found that the random copolymer brushes with the optimal ratio of AM to FMA in monomers showed the best protein-resistance performance, however, the optimal ratio is different for resisting bovine serum albumin and human plasma fibrinogen adsorption. For resisting bovine serum albumin adsorption, the optimal ratio of AM to FMA in monomers is 1 : 3, while the optimal is 3 : 1 for human plasma fibrinogen adsorption resistance. The results provide further evidence that surface compositional heterogeneities and microphase segregation of fluorinated moieties of amphiphilic random copolymer brushes significantly impact protein adsorption behaviors.
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RSC Advances
·
2016
·Vol. 6
·期 88
·85293-85302
·
IF 3.289
Kai Yan,Min Chen,Shuxue Zhou,Limin Wu
Multifunctional triggered drug release systems have been one of the most intriguing and challenging topics. In this study, we synthesize amphiphilic copolymers composed of hydrophilic oligo ethylene glycol methyl ether methacrylate and hydrophobic azobenzene-containing methacrylate. These amphiphilic copolymers can easily self-assemble into micelles in aqueous media and show smart responses to temperatures, UV/vis lights and ions. Interestingly, the obtained copolymers can self-assemble onto hydrophobic upconversion nanoparticles in aqueous media via hydrophobic interaction to form hybrid colloidal clusters with the hydrophobic nanocrystal core and hydrophilic polymeric shell. The hybrid colloidal clusters exhibit a thermo-responsive and photosensitive performance. When served as a drug carrier, both the near-infrared light and temperature triggered drug release can be realized, which have potential applications in intelligent drug delivery.
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COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
·
2019
·
IF 3.131
Mengyi Xu,Xiaojie Zhu,Hui Hong,Kezhen Hu,Ran Yang,Xiaoyu Wang,Xiaojie Li,Xiaoya Liu
Carbon nanotubules (CNTs) are an attractive material to enhance the properties of electrochemical sensors because of their excellent conductivity. However, their poor dispersibility limits their application. In this paper, CNTs were successfully dispersed and stabilized through co-assembly with the copolymer poly(VMc- co -VCz- co -AA) (PCMA). The resulting PCMA/CNT sensor was able to rapidly measure nitrite with a low detection limit (0.067 μM), and a wide linear range of 1 μm - 4 mM. It also exhibited high sensitivity, good selectivity and long-term stability.
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JOURNAL OF MOLECULAR LIQUIDS
·
2023
·
IF 6
Yu Chen,Jiaqi Li,Liping Zhao,Huan Chen,Xia Xin,Haihua Wang,Shenshen Li,Wenbing Kang
Owing to the high electronegativity of fluorine atoms, incorporation of fluorinated moieties in a polymer can confer unique properties such as low surface energy and self-assembling ability in solution. In this study, a series of amphiphilic copolymers were prepared by radical polymerization using three monomers: 2-((2,3,3,3- tetrafluoro- 2- (1,1,2,3,3,3- hexafluoro −2- (perfluoroethoxy) propoxy) propanoyl)oxy) ethyl acrylate (FHEMA), maleic anhydride (MAH), and acrylic acid (AA). The PFHEMA block provided low surface tension, and the MAH and AA blocks (containing carboxyl) increased solubility. The properties of the polymer (PFHEMA-co-PMAH-co-PAA) can be regulated by changing the PFHEMA length. Characterization by Fourier-transform infrared spectroscopy (FTIR) and gel permeation chromatography (GPC) indicated successful polymerization (FHA01 and FHA02). When the FHEMA/MAH/AA molar ratio was 3:8:9 (FAA02), the surface tension of the hydrolyzed amphiphilic copolymers FAA02 at 300 mg·mL −1 in aqueous solution was 15.76 mN·m −1 , the lowest value due to a higher fluorine content than FAA01. FAA02 self-assembled in water to form pH-sensitive micelles with diameters greater than 140 nm. For the FAA02 film, both the F/C ratio and arrangement of fluorine-containing side chains decreased with increasing film depth. Thus, this type of fluorine-containing low surface free energy material can be developed into a high performance coating material.
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Polymers
·
2022
·Vol. 14
·期 3
·406
·
IF 4.967
Xiao Wang,Xianghong Zheng,Xinyu Liu,Birong Zeng,Yiting Xu,Conghui Yuan,Lizong Dai
Due to unique chelating and macrocyclic effects, crown ether compounds exhibit wide application prospects. They could be introduced into amphiphilic copolymers to provide new trigger mode for drug delivery. In this work, new amphiphilic random polymers of poly(lipoic acid-methacrylate-co-poly(ethylene glycol) methyl ether methacrylate-co-N-isopropylacrylamide-co-benzo-18-crown-6-methacrylamide (abbrev. PLENB) containing a crown ether ring and disulphide bond were synthesized via RAFT polymerization. Using the solvent evaporation method, the PLENB micelles were formed and then used to load substances, such as doxorubicin hydrochloride (DOX) and gold nanoparticles. The results showed that PLENB exhibited a variety of lowest critical solution temperature (LCST) in response to the presence of different ions, such as K+, Na+and Mg2+. In particular, the addition of 150 mM K+increased the LCST of PLENB from 31 to 37 °C and induced the release of DOX from the PLENB@DOX assemblies with a release rate of 99.84% within 12 h under 37 °C. However, Na+and Mg2+ions could not initiate the same response. Furthermore, K+ions drove the disassembly of gold aggregates from the PLENB-SH@Au assemblies to achieve the transport of Au NPs, which is helpful to construct a K+-triggered carrier system.Keywords:crown ether;amphiphilic copolymers;K+-triggered;Au NPs;disassembly
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