CHEMOSPHERE
·
2024
·
IF 8.1
Yan Li,Zongyan Huang,Hui Zhang,Jieyu Zhao,Daolin Du
Plant-microbe remediation technique is considered as a promising technology in removal of organic pollutants and its remediation efficiency is largely affected by a variety of surrounding environmental factors. Humic acid (HA) is the complex organic substance ubiquitous in environment, which characterized by its surfactant-like micelle microstructure and various reaction activity. In our study, a plant-microbe association with high p - tert -Butylphenol (PTBP) degradation potential constructed by Spirodela polyrhiza and Sphingobium phenoxybenzoativorans Tas13 has been used, and the influence of HA on the PTBP degradation efficiency of S. polyrhiza -Tas13 association was investigated. The result showed that the presence of HA greatly improved PTBP removal efficiency of S. polyrhiza -Tas13. The reason accounted for this may be due to the presence of HA promoted bacterial cell propagation, altered bacterial cell wall permeability, increased catechol 2,3-dioxygenase (C23O) enzyme activity of strain Tas13, rather than increasing the colonization ability of strain Tas13 on to the root surface. This study will greatly facilitate the application of aquatic plant-microbe association in environmental remediation.
研究领域:
环境科学
·
微生物学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
POLYMER
·
2018
·
IF 3.483
Youjun He,Sheng Gao,Zaijun Lu
Mussel adhesive proteins (MAPs) are of an excellent adhesive property . The catechol structure (i.e., 1, 2-dihydroxybenzene) of 3, 4-dihydroxy-phenylalanine (DOPA) plays a key role in MAPs adhesion. Inspired by the MAPs adhesion, we synthesized catechol-based benzoxazine monomers (BOZ-ca) via Mannich reaction of catechol, aniline and paraformaldehyde, and then the polybenzoxazine containing catechol groups (PBOZ-ca) was obtained through the ring-opening polymerization of BOZ-ca in this work. The structure of BOZ-ca was characterized by 1 H NMR, 13 C NMR and FTIR. Interestingly, the DSC results show that the autocatalytic polymerization effect of BOZ-ca owing to the existence of phenolic hydroxyl groups decreases the polymerization temperature of BOZ-ca by ca. 80 °C compared with common benzoxazine monomers. The adhesion study results indicate that the catechol structure of PBOZ-ca increases its lap shear adhesion strength by 53% compared with common benzoxazine monomers, up to ∼2.61 MPa. The introduction of mussel-inspired structure provides a new design routine for the improvement of polybenzoxazine adhesion property.
研究领域:
材料科学
·
生物仿生学
✓ 已验证
DOI
高影响因子
APPLIED SURFACE SCIENCE
·
2020
·
IF 6.182
Youbing Mu,Pengzhou Mu,Xiao Wu,Xiaobo Wan
Many factors govern the underwater adhesion of mussels, among which the synergic effect of charged amino group and catechol moiety in mussel foot-byssus proteins has been discovered recently. Here we show that although very important, spatial proximity might not be the prerequisite for the synergic effect between amino and catechol groups in underwater adhesion. By designing probes grafted with monomer integrated with both groups and with monomers carrying the two groups separately, we revisted the synergic effect at nanoscale level. It is found that the synergic effect has two facets: first, the presence of both groups enable stronger adhesion in electrolyte solutions than the presence of catechols alone, and this effect does not require catechols and amine cations to be next to each other in space. Second, only when the catechol and cation are paired and next to each other, the adhesion force could be further enhanced in low pH solutions, which means the dependence of synergic effect on the spatial proximity of catechols and amine cations is conditional to the acidity of the electrolyte solution. We reason that besides the already discovered effect in protecting catechol from oxidation, acid condition contributes to underwater adhension by interfering with the formation of the hydration layer, which helps the eviction of absorbed cations and the coordination of catechol sequentially when the catechol and amino cation are spatially next to each other.
研究领域:
生物化学
·
材料科学
✓ 已验证
DOI
高影响因子
ACS Biomaterials Science & Engineering
·
2022
·
IF 5.395
Zuwu Tang,Min Zhang,He Xiao,Kai Liu,Xiuliang Li,Bihui Du,Liulian Huang,Lihui Chen,Hui Wu
Traditional adhesives with strong adhesion are widely applied in the fields of wood, building, and electronics. However, the synthesis and usage of commercial adhesives are not eco-friendly, which are harmful to human health and to the environment. In this study, a green cellulose nanofibrils/poly(hydroxyethyl methacrylate-co-dopamine methacrylamide) (CNFs/P(HEMA-co-DMA)) adhesive with excellent biocompatibility and strong bonding strength has been fabricated. P(HEMA-co-DMA) with a catechol content of 7.1 mol % was synthesized using dopamine methacrylamide and hydroxyethyl methacrylate. The CNFs/P(HEMA-co-DMA) adhesive was generated by cross-linking P(HEMA-co-DMA) solution using cellulose nanofibrils (CNFs). Strong adhesion was realized on various substrates, with a maximum lap shear strength of 5.50 MPa on steel. The NIH 3T3 cells test demonstrated that the adhesive possessed excellent biocompatibility. The green catechol-containing CNFs-cross-linked adhesive has promising potential for applications in medicine, electronic, food packaging, and engineering.
研究领域:
材料科学
·
胶粘剂
·
绿色化学
·
生物医学工程
·
高分子科学
✓ 已验证
DOI
高影响因子
JOURNAL OF APPLIED POLYMER SCIENCE
·
2021
·Vol. 138
·期 46
·51382
·
IF 3.125
Longfang Ren,Congcong Lin,Pingchuan Lei
A series of waterborne polyurethane (PDMAPU) containing catechol group were prepared by double-bond random copolymerization of terminated double bond polyurethane prepolymer with modified acrylamido dopamine under thermal initiation. This kind of mussel-like waterborne polyurethane adhesive is inspired by marine mussel, as well as it is environment-friendly and used in bonding of leather. FTIR and 1 H NMR proved the successful introduction of catechol group into polyurethane matrix. Oxidative cross-linking between catechol unit and molecular chain in PDMAPU structure, the thermal stability and crystallization ability of PDMAPU was significantly improved. The increase of the particle size of PDMAPU emulsion showed that the introduction of catechol group changed the microstructure of polyurethane and enhanced the cross-linking degree. The water resistance of polyurethane emulsion was further improved. Compared with PU without catechol group, the peel strength of leather substrate adhered by PDMAPU emulsion increased from 0.42 to 1.93 MPa, which indicated that PDMAPU has better bonding properties with leather. The bidentate hydrogen bond formed with catechol group as the reaction sites is considered to be the key reason for the adhesion of mussel-like polyurethane adhesive to hydrophilic substrates. This work provides an alternative to prepare environment-friendly high performance adhesive for hydrophilic substrates.
研究领域:
材料科学
·
化学工程
·
生物仿生学
✓ 已验证
产品关联
DOI
高影响因子
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2026
·
IF 8.7
Te Pan,Peiying Zheng,Ruixu Cai,Dongqing Tang,Min Wang,Saiyi Zhong,Xiaolong Ji,Maria Kulp,Marina Kudrjashova,Udayakumar Veerabagu,Timo Kikas,Kit-Leong Cheong
Alginate-catechol hydrogels with varying degrees of substitution (DS) were prepared. • DS regulated hydrogel physicochemical and biological properties. • The hydrogel with a DS of 17.5% showed the best overall performance. • The optimized hydrogel promoted oral ulcer healing in rats. Oral ulcers are common inflammatory lesions of the oral mucosa, yet their local treatment remains challenging because the moist and dynamic oral environment limits the retention and efficacy of conventional formulations. Herein, we developed a series of bioadhesive alginate-catechol (Alg-cat) hydrogels with different degrees of substitution (DS) and systematically investigated the influence of DS on their physicochemical properties, biological performance, and therapeutic effects on oral ulcer healing. The hydrogels were characterized by structural analyses, swelling and degradation tests, adhesion and mechanical measurements, antioxidant and antibacterial assays, and biocompatibility evaluation. The results showed that DS critically regulated hydrogel performance. Increasing DS enhanced network density, mechanical strength, reactive oxygen species (ROS) scavenging ability, and antibacterial activity, whereas adhesion and deformability reached optimal levels at an intermediate DS. Among all formulations, the Alg-cat hydrogel with a DS of 17.5% exhibited the most balanced properties, including the highest adhesion strength, favorable mechanical adaptability, strong antioxidant and antibacterial activities, and good biocompatibility. In a rat oral ulcer model, this optimized hydrogel significantly accelerated wound healing, with efficacy comparable to that of a dexamethasone patch after 5 days of treatment. Further analyses demonstrated that it reduced inflammatory cell infiltration, promoted collagen deposition and epithelial regeneration, regulated inflammatory cytokine expression, and facilitated macrophage polarization toward the M2 phenotype. Overall, this study identifies DS as a key determinant of catechol-grafted alginate hydrogel performance and highlights the optimized Alg-cat hydrogel as a promising drug-free therapeutic platform for oral ulcer treatment.
✓ 已验证
DOI
PubMed
高影响因子
SENSORS
·
2026
·Vol. 26
·期 11
·3550
·
IF 4
Xiaoying Shen,Muyu Yan,Qiongya Wan,Ming Li,Xuefeng Wang,Pengcheng Xu,Yongheng Zhu
Catechol, a prevalent phenolic pollutant in food products, poses a significant threat to food safety, necessitating the development of rapid and sensitive detection methods. To overcome the limitations of conventional analytical techniques, such as expensive equipment and operational complexity, electrochemical sensors have gained considerable attention owing to their rapid response and facile miniaturization. However, the rational design of sensing materials that exhibit both high sensitivity and selectivity remains a significant challenge. Herein, a series of PdCu bimetallic nanoparticles supported on reduced graphene oxide (PdCu@rGO) composites with varying Pd/Cu molar ratios was synthesized via a one-step liquid-phase reduction method. Owing to the synergistic electronic effects between Pd and Cu and the high electrical conductivity of the rGO support, the resulting nanocomposites exhibited excellent electrocatalytic activity toward catechol oxidation. At the optimal Pd/Cu molar ratio of 1:2, the fabricated Pd1Cu2@rGO/SPE sensor demonstrated a broad linear range of 0.5–500 μM, a low limit of detection of 200 nM (S/N = 3), good repeatability (RSD = 4.9%), and robust anti-interference capability. Furthermore, the proposed sensor was successfully applied to the detection of catechol in spiked green tea and fruit juice samples without complex pretreatment, achieving satisfactory recoveries of 91.0–101.4% and 98.6–104.8%, respectively. This work provides a reliable platform for the rapid, on-site screening of catechol in food matrices and offers valuable experimental insights into the rational design of bimetallic alloy–graphene heterostructures.
✓ 已验证
DOI
PubMed
高影响因子
Materials Science & Engineering C-Materials for Biological Applications
·
2019
·
IF 4.959
Kunyu Zhang,Zi Wei,Xiayi Xu,Qian Feng,Jianbin Xu,Liming Bian
Hydrogels are promising soft materials for the delivery of therapeutic cells and cargo molecules. Inspired by mussel adhesion chemistry, hydrogels based on catechol (Cat)-modified polysaccharides have been developed to enhance hydrogel–tissue interactions. However, due to the inevitable side reactions such as self-polymerization of dopamine involved in the conventional catechol conjugation process, the efficiency of catechol conjugation to polymers is typically low, leading to insufficient stability, low mechanical strength, and poor adhesiveness of these catechol-modified hydrogels. In this study, we report a new approach to synthesize catechol-functionalized hyaluronic acid with improved degree of substitution. Due to the significantly increased conjugated Cat groups, the obtained HA-Cat hydrogels not only can adhere to tissue samples under wet conditions but also can capture cell adhesion proteins to enhance cell attachment and spreading. Meanwhile, owing to the extensive Cat–protein interactions, these hydrogels can also facilitate long-term release of protein-based therapeutic cargoes, such as the osteoinductive BMP-2 protein, thereby effectively promoting osteogenic differentiation of stem cells. These findings show that the HA-Cat hydrogels are ideal carriers of therapeutic cells and drugs for tissue regeneration.
研究领域:
材料科学
·
生物医学工程
·
组织工程
·
药学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Materials Today Bio
·
2022
·
IF 10.761
Bingyang Lu,Xiao Han,Dan Zou,Xiao Luo,Li Liu,Jingyue Wang,Manfred F. Maitz,Ping Yang,Nan Huang,Ansha Zhao
Chronic wounds and the accompanying inflammation are ongoing challenges in clinical treatment. They are usually accompanied by low pH and high oxidative stress environments, limiting cell growth and proliferation. Ordinary medical gauze has limited therapeutic effects on chronic wounds, and there is active research to develop new wound dressings. The chitosan hydrogel could be widely used in biomedical science with great biocompatibility, but the low mechanical properties limit its development. This work uses polyacrylamide to prepare double-network (DN) hydrogels based on bioadhesive catechol-chitosan hydrogels. Cystamine and N, N′-Bis(acryloyl)cystamine, which can be cross-linking agents with disulfide bonds to prepare redox-responsive DN hydrogels and pH-responsive nanoparticles (NPs) prepared by acetalized cyclodextrin (ACD) are used to intelligently release drugs against chronic inflammation microenvironments. The addition of catechol groups and ACD-NPs loaded with the Resolvin E1 (RvE1), promotes cell adhesion and regulates the inflammatory response at the wound site. The preparation of the DN hydrogel in this study can be used to treat and regulate the inflammatory microenvironment of chronic wounds accurately. It provides new ideas for using inflammation resolving factor loaded in DN hydrogel of good biocompatibility with enhanced mechanical properties to intelligent regulate the wound inflammation and promote the wound repaired.
研究领域:
生物医学工程
·
材料科学
·
炎症研究
✓ 已验证
产品关联
DOI
PubMed
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2022
·
IF 16.744
Yibo Shen,Baolong Wang,Da Li,Weihao Yuan,Yudong Huang,Zhen Hu
Widely used traditional thermosets have drawn great attention due to their advantageous features such as excellent stability, mechanical reliability etc. However, brittleness is still the weak point in their extensive applications. Herein, a synthetic strategy to incorporate catechol groups into polymer structures via thiol-epoxy click chemistry was developed, the covalent and iron-catechol coordination bonds are combined to build up the material consisting of two types of crosslinks. As an important design feature of thermoset, catechol moiety provided the potential of gaining recoverable hysteretic energy dissipation through iron-catechol complexes. Favorable thermal properties comparable to commercial resin were retained, and mechanical testing revealed the thermoset exhibited high extensibility, such that it can be stretched to over 100 % with a fracture strength of 31.16 MPa, along with the tensile strength can be maintained 90.53 % after 5 cycles at the strain of 50 %. The synergistic interaction additionally providing the possibility of shape memory response to specific environmental changes, either by heat or by ultraviolet light. These behaviors further highlight the utility of dynamic coordinate bonds in the preparation of versatile thermosets, which could be potentially applied in smart devices and advanced materials.
研究领域:
材料科学
·
高分子化学
✓ 已验证
产品关联
DOI
高影响因子
ACS Applied Materials & Interfaces
·
2018
·
IF 8.097
Wen-Ze Qiu,Guang-Peng Wu,Zhi-Kang Xu
Bioinspired polyphenol/polyamine codeposition has been demonstrated by the competence for surface modification; however, the reaction processes including mechanism and kinetics remain superficially understood. In this work, the catechol (CA)–amine reaction has been thoroughly investigated by using CA and two amines m-phenylenediamine and piperazine. We verify that both primary and secondary amines are prone to link with CA through Michael addition to form polyphenol/polyamine oligomers under aerobic and mild-alkaline conditions. Molecular simulations indicate that the Michael addition products are dominant for both aromatic and aliphatic amines with CA, which supports the durable chem- and phystability of the codeposited coatings. The aggregation kinetics of polyphenol/polyamine is provided for the first time, and the formed aggregates show high-adhesive properties, which can be deposited as the skin layers for high-performance nanofiltration membranes.
研究领域:
材料科学
·
表面化学
·
聚合物化学
·
膜技术
✓ 已验证
产品关联
DOI
PubMed
高影响因子
APPLIED SURFACE SCIENCE
·
2022
·
IF 7.392
Dandan Zhou,Youxi Wang,Yuniu Sun,Jiefu Zhang,Dan Wang,Zhenyu Li,Xiang Shao
The details of catechol interacting with the ZnO surfaces are critical for understanding how the organic chromophores anchor on and hence functionalize the ZnO materials. In this work, we apply low-temperature scanning tunneling microscopy (LT-STM) in combination with density functional theory (DFT) calculations to investigate the adsorption state and interface charge transfer of catechol on a ZnO(10-10) surface. For the molecules deposited at liquid nitrogen temperature, the fully-protonated (FP) status prevails in the isolated molecules despite the synergistic formation of half-protonated (HP) and fully-deprotonated (FD) ones. However, annealing to elevated temperature drives all the molecules to assemble into either linear or a c(2 × 2) superstructure composed of only FD catechols. Such spontaneous deprotonation of catechol is different from the predicted water-assisted process and plays critical roles in switching the catechol from electron acceptors to electron donors relative to the ZnO surface. These results may bring new insights into the design of optoelectronic and biomedical applications of the ZnO-organic compositional system.
研究领域:
材料科学
·
表面化学
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）