MICROCHIMICA ACTA
·
2019
·Vol. 186
·期 8
·1-8
·
IF 5.479
Jiang Dandan,Li Zheng,Jia Qiong
The design and preparation of magnetic cucurbit[6]uril hypercrosslinked
with polymers are described. The materials have a large specific surface, abundant
mesopores and cavities, and display superparamagnetism. They were applied to the
enrichment of ubiquitinated peptides from standard protein digests. Following
desorption with 0.15% TFA, the peptides were quantified by MALDI-TOF MS. The method
has a detection limit of 2 fmol·μL −1 and a mass
ratio selectivity of 1:5000 as shown for ubiquitin and bovine serum albumin. The
materials enable selective capture of ubiquitinated peptides from genuine samples
comprising of oyster mushroom and human serum. This demonstrates their potential for
the analysis of low-level ubiquitin in complex samples.
Schematic presentation for the synthesis of magnetic
cucurbit[6]urils hypercrosslinked polymers
(MagCB[6]-HCPs).
研究领域:
生物化学
·
分析化学
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PubMed
高影响因子
PHYSICAL CHEMISTRY CHEMICAL PHYSICS
·
2022
·Vol. 24
·期 22
·13773-13783
·
IF 3.945
Xian-Yi Jin,Xin Dai,Jie Zhao,Qingmei Ge,Mao Liu,Zhu Tao,Hang Cong
A supramolecular polymer was developed through the encapsulation of polypyrrole by cucurbit[6]uril (PPy@Q[6]), which was employed as the electrode material to improve the capacitor ability of conductive polypyrrole. In the optimized ratio of 2 : 1 (CPPy : CQ[6]), the capacitor properties of the supramolecular material were evaluated, and a high specific capacitance of 414 F g−1 at 10 mV s−1 was obtained, which was 3.1 times higher than that of pure polypyrrole (132 F g−1). A comprehensive analysis suggested that the capacitance performances should be relevant to the component, surface area, and pore volume of the materials. The addition of 0.4 M Fe2(SO4)3 into the electrolyte provided a surprising specific capacitance of 3530 F g−1 on the cucurbituril-encapsulated polypyrrole electrode material, with a high energy density of 707 W h kg−1 at a power density of 32 000 W kg−1 and a current density of 8 A g−1. The 81.6% capacitance retention maintained after 1000 cycles revealed the acceptable cycling capacity of the proposed supramolecular supercapacitor system, which demonstrated good performance even at a low temperature of −20 °C.
研究领域:
材料科学
·
电化学
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PubMed
高影响因子
POLYHEDRON
·
2022
·
IF 2.975
Jian-Hang Hu,Zhi-Chao Yu,Jia-Yi Zhang,Zhi-Nian Liu,Run-Xin Hou,Yu Xiong,Carl Redshaw,Zhu Tao,Xin Xiao
The interaction between symmetric tetramethyl cucurbit[6]uril (TMeQ[6]) and 2,3-dimethylphenylpiperazine hydrochloride (PMY) has been studied in the presence of [CdCl 4 ] 2− . Each port of the TMeQ[6] is connected to PMY through weak interactions such as ion dipole interactions and C H⋯O hydrogen bonding interactions, whilst the [CdCl 4 ] 2− is connected with the portal carbonyl oxygen, glycoside urea methylene and a bridging methylene of a TMeQ[6] molecule via ion–dipole interactions. These interactions were evident from a single crystal X-ray diffraction study of TMeQ[6]-PMY-[CdCl 4 ] 2− . In addition, the complex can form a one-dimensional supramolecular chain structure, and then assemble into a two-dimensional supramolecular framework, which can be described as a TMeQ[6]-PMY-[CdCl 4 ] 2− based supramolecular framework (QSF).
研究领域:
化学
·
材料科学
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DOI
高影响因子
NEW JOURNAL OF CHEMISTRY
·
2019
·Vol. 43
·期 26
·10297-10304
·
IF 3.069
Xi Xia,Wei Wei Ge,Haiyong Chen,Zhu Tao,Yunqian Zhang,Gang Wei,Kai Chen
In the present work, perhydroxylated cucurbit[6]uril {(HO)12Q[6]} and Keggin-type polyoxometallates (POMs) such as H3[PMo12O40] and H3[PW12O40] were used as basic building blocks, and interaction of (HO)12Q[6] of POMs in the acidic aqueous solutions yielded two types of supramolecular assemblies. Hybrids of (HO)12Q[6] with POM anions were obtained from (HO)12Q[6]-POMs-HCl (1M) systems, whereas (HO)12Q[6]-based supramolecular assemblies without POMs were obtained from (HO)12Q[6]-POMs-HCl (6M) systems. The structures of these two assemblies were analyzed by using single X-ray single crystal and powder X-ray diffraction methods, and the chemical and physical properties of these two assemblies were investigated by using the multi-point Brunauer–Emmett–Teller (BET) method, the Barrett–Joyner–Halenda (BJH) method, UV/vis measurements and so on. The results revealed that the (HO)12Q[6]-POMs system may offer a feasible route for the uptake and release of POMs, exhibit esterification and aqueous dyes degradation catalytic activities, and adsorb volatile organic compounds, yielding adsorbing materials with interesting photochemical properties.
研究领域:
化学
·
材料科学
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DOI
高影响因子
Surfaces and Interfaces
·
2025
·
IF 6.3
Fuzhi Li,Jian Zhang,Bo Yu,Jianqiang Meng
The simultaneous optimization of permeability and selectivity remains a cardinal challenge in advancing organic solvent nanofiltration (OSN). However, conventional OSN membranes are fundamentally constrained by the “trade-off” problem between permeability and selectivity. To break this limitation, we successfully prepared polyamide thin-film composite (PA-TFC) OSN membranes with both high permeability and high selectivity by incorporating cucurbit[6]uril (CB[6]) into the PA layer. The water insolubility of CB[6] was addressed through complexation with polyethyleneimine (PEI). The successful complexation of CB[6] was verified using techniques such as Ultraviolet-visible spectrophotometer (UV–Vis), Field emission scanning electron microscope (FE-SEM), and other testing approaches. The impact of CB[6] on the chemical composition and surface morphology of the PA layer was also systematically analyzed. In addition, we investigated the effects of monomer concentration on the membrane of permeability-selectivity performance. Experimental results show that the modified membrane, by building the solvent transport channels, showed significantly enhanced methanol permeability (increased by 164 %, 3.19 vs 1.21 L·m -2 ·h -1 ·bar -1 ), while preserving the satisfactory rejection capacity for small molecules (390 Da) (>90 %). Based on the physical parameters of different solvents, we further analyzed the solvent transport mechanism of the prepared OSN membrane. This study provides new insights and approaches for the design of high performance nanofiltration membranes with the aid of macrocycles.
研究领域:
膜科学
·
纳滤
·
材料科学
·
化学工程
·
分离技术
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DOI
高影响因子
JOURNAL OF MOLECULAR STRUCTURE
·
2025
·
IF 4.7
Pei-hui Shan,Tai-bai Jiang,Hang Zhao,Xiao-yan Wu,Carl Redshaw,Zhu Tao,Xin Xiao
The interaction between 1-(2-hydroxyphenyl)piperazine (HPP) and cucurbit[6]uril (Q[6]) has been explored via 1 H NMR spectroscopy and X-ray crystallography. The results show that the guest molecule 1-(2-Hydroxyphenyl)piperazine hydrochloride is not encapsulated within the Q[6] cavity in both aqueous solution and the solid state. Instead, it resides at the portal of Q[6], forming a highly stable exclusion complex, designated HPP 2 @Q[6]. Notably, ion-dipole and hydrogen-bonding interactions play key roles in stabilizing this complex.
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JOURNAL OF MOLECULAR STRUCTURE
·
2017
·
IF 1.753
Kai Chen,Jing Xu,Sheng-Chao Qiu,Yuan Wang,Min-Dong Chen,Yun-Qian Zhang,Xin Xiao,Zhu Tao
We investigated the interactions in an inverted cucurbit[6]uril ( i Q[6]) with a series of 1, ω -alkyldimins and their supramolecular assemblies in the presence of the tetrachlorozincate anion ([ZnCl 4 ] 2− ) structure directing agent . i Q[6] forms an outer surface interaction with [ZnCl 4 ] 2− to form different i Q[6]/[ZnCl 4 ] 2− -based supramolecular assemblies with different length 1,ω-alkyldimins. Interestingly, most 1,ω-alkyldimins were not visible in crystals structures in the presence of concentrated HCl. The porous i Q[6]/[ZnCl 4 ] 2− -based supramolecular assemblies could be used as materials for adsorbing volatile compounds .
研究领域:
化学
·
材料科学
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高影响因子
SEPARATION AND PURIFICATION TECHNOLOGY
·
2019
·
IF 5.107
Dongze Wang,Xuemei Li,Xiangqun Jin,Qiong Jia
In the present study, cucurbit[6]uril-based hypercrosslinked polymers (HCPs) were successfully synthesized and employed for the capture of albendazole, a broad-spectrum anthelmintic drug. Fourier-transform infrared spectroscopy, elemental analysis, powder X-ray diffraction, scanning electron microscopy, thermogravimetric analysis, and N 2 adsorption-desorption measurements were used to prove the successful preparation of the desired HCPs. Thanks to the encapsulation of cucurbit[6]uril toward albendazole and the high surface area of HCPs, remarkable adsorption capacity of albendazole was achieved. The adsorption behavior followed Langmuir adsorption isotherm with a negative value of Gibbs free energy change, suggesting a spontaneous adsorption process. In addition, the kinetics of albendazole adsorption was investigated, which could be described with the pseudo-second-order kinetics model.
研究领域:
材料科学
·
药物化学
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DOI
高影响因子
ACS Nano
·
2023
·
IF 17.1
Delong Hou,Yong Xu,Jun Yan,Qi Zeng,Zhonghui Wang,Yi Chen
Using a photochemically isomerizable cucurbit[6]uril derivative as a building block, we succeeded in generating a large number of oversized 2D materials within the cytosol of a living cell via controlled self-assembly. Fluorescence recovery after a photobleaching assay indicated that the resulting 2D material pieces posed discernible hindrance to not only diffusive spreading but also motor-driven motion of intracellular components in the cytosol, which eventually induced apoptotic cell death. Such behavior was seldom observed in previous 2D material-bearing cells prepared by endocytosis, as the total lateral size constituted by the endocytosed 2D materials per cell failed to exceed a threshold level, leading to a tortuosity of transport path inadequate to impede cytosolic transport in an appreciable manner. By varying the initial concentration of the building block, the existence of such a threshold was experimentally demonstrated from the relationship between the flow cytometry side scatter of the treated cells and corresponding cell viability. With the otherwise well-regulated cytosolic transport dynamics of living cells being physically altered, therapeutics with a new mechanism of action that counteracts drug resistance or intracellular platforms that advance our understanding of subcellular pathology of certain intractable diseases are in sight.
研究领域:
细胞生物学
·
纳米医学
·
药物开发
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DOI
PubMed
高影响因子
JOURNAL OF SEPARATION SCIENCE
·
2015
·Vol. 38
·期 7
·1082-1089
·
IF 2.737
Liyun Ma,Simin Liu,Qing Wang,Lin Yao,Li Xu
In the present study, one of the new generation of host molecules, cucurbit(6)uril (CB(6)), was immobilized onto silica (CB(6)/SiO 2 ) by a sol–gel approach. CB(6)/SiO 2 was characterized by NMR spectroscopy, Fourier transform infrared spectroscopy, thermogravimetric analysis, and elemental analysis. It was used as a high-performance liquid chromatographic stationary phase and its chromatographic performance was systematically investigated with different types of analytes as probes. The results revealed that the CB(6)/SiO 2 stationary phase exhibited weak hydrophobic and strong hydrophilic properties. Hence, the variables for hydrophilic interaction liquid chromatography, including components and pH of the mobile phase, were further investigated to explore the retention mechanism of this CB(6)/SiO 2 stationary phase. For less polar analytes, both hydrophobic and hydrophilic interactions could contribute to the retention, while for polar analytes, hydrophilic interaction may be predominant. Compared to the tetraethoxylsilane-coated SiO 2 stationary phases, the CB(6)/SiO 2 stationary phase exhibited a different retention behavior toward basic analytes with excellent stability. It is a novel promising hydrophilic interaction liquid chromatography stationary phase.
研究领域:
分析化学
·
材料科学
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DOI
PubMed
高影响因子
DYES AND PIGMENTS
·
2025
·
IF 4.2
Xin Lin,Fang-Fang Shen,Ren-Jie Song
In this study, two novel fluorescent probes, H 1 /G and H 2 /G, were constructed using two alkyl-substituted cucurbit[6]urils (CB[6]s), H 1 and H 2 , and a cationic dye guest, G. The G molecules were encapsulated within the cavities of CB[6] hosts, forming 1:1 host–guest complexes. While free G molecules exhibited negligible fluorescence in solution, the inclusion complexes demonstrated a strong fluorescence signal (618 nm). The detection limits for glutamic acid (Glu) recognition by the two probes were as low as 2.98 × 10 −7 M and 4.20 × 10 −7 M, respectively. Notably, although the two modified CB[6]s differed by only a single substituent, their resulting probes demonstrated different degrees of amino acid recognition ability. The H 2 /G probe was capable of recognizing both Glu and lysine (Lys), while the H 1 /G probe detected only Glu. By employing structurally modified CB[6]s as hosts and constructing CB[6]-based fluorescent probes capable of selectively recognizing non-aromatic amino acids, this study paves the way for the biological applications of CB[6]-based supramolecular host–guest systems.
研究领域:
超分子化学
·
分析化学
·
生物有机化学
·
荧光传感
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DOI
高影响因子
INORGANICA CHIMICA ACTA
·
2021
·
IF 2.545
Wen Xia,Yu-Mei Nie,Na Lei,Zhu Tao,Qiang-Jiang Zhu,Yun-Qian Zhang
The esterification reaction used to prepare butyl paraben (BP) and propyl gallate (PG) catalyzed using a cucurbit[6]uril-supported Keggin-type silicotungstic acid (Q[6]-STA) catalyst has been investigated. The Q[6]-STA catalyst has been characterized using FTIR spectroscopy, XRD, SEM, EDS, thermal analysis, and surface area studies. Q[6]-STA was easy to prepare in high yield and exhibited some advantageous properties, such as high catalytic activity and its convenient recovery. Moreover, a reusability study showed that the Q[6]-STA catalyst was stable and active.
研究领域:
化学工程
·
材料科学
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高影响因子
危险品化学品经营许可证（带存储）