Polymers
·
2020
·Vol. 12
·期 11
·2631
·
IF 3.426
Kun Luo,Li Wang,Xiaohu Chen,Xiyang Zeng,Shiyi Zhou,Peicong Zhang,Junfeng Li
In this study, a novel polyurethane porous 3D scaffold based on polyethylene glycol (PEG) and polytetrahydrofuran glycol (PTMG) was developed by in situ polymerization and freeze drying. Aliphatic hexamethylene diisocyanate (HDI) as a nontoxic and safe agent was adopted to produce the rigid segment in polyurethane polymerization. The chemical structure, macrostructure, and morphology—as well as mechanical strength of the scaffolds—were characterized by Fourier transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), scanning electron microscope (SEM), and tensile tests. The results show that the HDI can react mildly with hydroxyl (–OH) groups of PEG and PTMG, while gas foaming action caused by the release of CO2occurred simultaneously in the reactive process, resulting in a uniform porous structure of PU scaffold. Moreover, the scaffolds were soaked in water and freeze dried to obtain higher porosity and more interconnective microstructures. The scaffolds have a porosity of over 70% and pore size from 100 to 800 μm. The mechanical properties increased with increasing PEG content, while the hydrophilicity increased as well. After immersion in simulated body fluid (SBF), the scaffolds presented a stable surface structure. The gas foaming/freezing drying process is an excellent method to prepare skin tissue engineering scaffold from PTMG/PEG materials with high porosity and good inter connectivity.
研究领域:
生物材料学
·
组织工程学
✓ 已验证
DOI
高影响因子
JOURNAL OF CHEMICAL AND ENGINEERING DATA
·
2016
·
IF 1.835
Kai Kang,Xiaopo Wang,Fuxin Yang,John M. Prausnitz
Experimental density data are reported for diethylene glycol monobutyl ether, diethylene glycol dibutyl ether, and ethylene glycol monobutyl ether from (283.15 to 363.15) K at pressures up to 60 MPa using a vibrating-tube densimeter. Relative uncertainties of density measurements are 0.001 with confidence level 0.95. The experimental data were fitted with a Tait-like equation; average relative deviations were 0.017% for diethylene glycol monobutyl ether, 0.015% for diethylene glycol dibutyl ether, and 0.019% for ethylene glycol monobutyl ether. The isobaric thermal expansivity and the isothermal compressibility were derived from the Tait-like equation.
研究领域:
物理化学
·
流体性质研究
·
高压物性分析
·
化工热力学
✓ 已验证
DOI
高影响因子
SEPARATION AND PURIFICATION TECHNOLOGY
·
2025
·
IF 9
Wei Chen,Yan Ding,Fang Wang,Zhixia Xu,Qing Ye,Jinlong Li,Patrice Paricaud
The vapor-liquid equilibria of binary mixtures of ethylene glycol diacetate (EGDA) + o-chlorotoluene (OCT) and EGDA + cyclohexylbenzene (CHB), and the liquid-liquid equilibria (LLE) in ternary mixtures of ethylene glycol (EG) + EGDA + o-chlorotoluene and EG + EGDA + cyclohexylbenzene are measured in this work. The new data have been described with the NRTL thermodynamic model. The heterogeneous extractive distillation and liquid-liquid phase separation process for the investigated systems are then simulated using the Aspen Plus software and the adjusted thermodynamic model. The influence of key process parameters such as the ratio of solvent flow rate to feed flowrate, the plate number and the reflux ratio on the separation process are analyzed in detail, and the optimal process parameters are determined. An economic and environmental study of the process is then performed. It is found that the two extractants (o-chlorotoluene and cyclohexylbenzene) can achieve a good EG + EGDA azeotrope separation. The purities of both EG and EGDA products are greater than 99.50 wt% in the two processes. The predicted selectivity obtained with o-chlorotoluene is higher than the one obtained with cyclohexylbenzene process. However, the cyclohexylbenzene process is found to be was more environmentally friendly, and the utility costs and CO 2 emissions of are lower. This work brings new insights in the design and optimization for the separation of EG and EGDA azeotropic mixtures.
研究领域:
化学工程
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过程系统工程
·
热力学
·
环境工程
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF CHEMICAL AND ENGINEERING DATA
·
2012
·
IF 1.693
Hai Zhang,Rulong Li,Baogen Su,Huabin Xing,Yiwen Yang,Qilong Ren
The triethylene glycol and tripropylene glycol derivatives terminated with the CO2-philic phosphoryl groups, named 2-(2-(2-((2-ethylhexoxy(methoxy)phosphoryl)oxy)ethoxy)ethoxy)ethyl 2-ethylhexyl methyl phosphate (EG3EH) and 2-(2-(2-((2-ethylhexoxy(methoxy)phosphoryl)oxy)propoxy)propoxy)propyl 2-ethylhexyl methyl phosphate (PG3EH), were synthesized and characterized. The solubilities of EG3EH and PG3EH in scCO2 were determined by a static method at temperatures from (313 to 333) K and over a pressure range of (10 to 19) MPa. The values calculated by the Bartle semiempirical model exhibited good agreement with the experimental data.
研究领域:
化学工程
·
材料科学
✓ 已验证
产品关联
DOI
高影响因子
Materials Express
·
2023
·Vol. 13
·期 7
·1274-1285
·
IF 0.7
Tian Zenan,Liu Jidong,Liu Yida,Li Wensong,Zhang Ridong,Lv Jianhua
Activation is essential for improving the structure and surface functional groups of carbon-based solid acids (CSA) during the preparation of carbon materials. This paper compared the catalytic activity of CSA treated non-, KOH-, H3PO4-, and ZnCl2-activation
in esterification of ethylene glycol (EG) and acetic acid (HAc) to synthesize ethylene glycol monoacetate (EGMA). The catalysts were characterized using N2 isothermal adsorption–desorption, acid-base titration, Fourier transform infrared (FT-IR) spectroscopy, scanning electron
microscopy (SEM), Raman spectrometer, X-ray photoelectron spectroscopy (XPS), and X-ray diffractometer analysis (XRD). The results showed that activation treatment clearly enhanced the CSA’s specific surface area and significantly influenced the distribution of surface functional groups.
Notably, the CSA activated with H3PO4 had a markedly higher density of –SO3H groups than the non- activated, KOH- activated, and ZnCl2-activated CSA. The high density of –SO3H on the catalyst surface is advantageous for the
synthesis of EGMA from EG and HAc, making the H3PO4-activated CSA the best performer. The reaction conditions were optimized on H3PO4-activated CSA, resulting in a 74.1% conversion of EG and an 81.8% selectivity of EGMA at 100 °C for 30 min,
and the EG/HAc molar ratio of 1:2. H3PO4-activated CSA was not obviously deactivated even after five cycles, and the decrease of its catalytic performance was related to the leaching of –SO3H on the catalyst surface. Overall, these findings suggest that
H3PO4-activated CSA offers the benefits of less cost, a simpler preparation method, and greater catalytic activity compared to other catalysts, making it a desirable option for the synthesis of EGMA.
研究领域:
化学工程
·
催化材料
✓ 已验证
DOI
高影响因子
Advanced Composites and Hybrid Materials
·
2023
·Vol. 6
·期 1
·1-9
·
IF 20.1
Chen Cheng,Wang Xi,Wang Yan,Gu Hongxi,Zhao Weixing,Zhang Wenxiong,Sewvandi Galhenage Asha,Wang Bo,Ma Chunrui,Liu Ming,Hu Dengwei
Digital light processing (DLP) 3D printing technology is widely applied in the fabrication of ceramics owing to the good printing precision and printing speed. Barium titanate (BaTiO 3 , BT) has attracted extensive attention of researchers due to the good piezoelectric constant, strong dielectric constant, and ease of integration. Therefore, DLP 3D printing technology is combined with the production of BaTiO 3 /1,6-ethylene glycol diacrylate/Polyethylene glycol (400) diacrylate (BT/HDDA/PEG(400)DA) nanocomposites to improve the electrical properties. A preparation method for composite slurry with high fluidity, high solid content, and low viscosity is proposed by comparing the electrical properties of BT/HDDA/PEG(400)DA nanocomposite fabrication with different solid content. The work demonstrates that 67 wt% BT/HDDA/PEG(400)DA nanocomposites are better solid content to DLP 3D printing technology and the printed nanocomposite has the excellent electric properties. After a post-processing, the 67 wt% nanocomposite slurry shows the higher relative density (91.69%) and exhibits piezoelectric constant, remnant polarization, and dielectric constant of 151 pC/N, 17.4 μC/cm 2 , and 7712, respectively. The results suggest that the DLP 3D printing technology provides an alternative method for the fabrication of complex functionality nanocomposite piezoelectric elements. Graphical Abstract
研究领域:
材料科学
·
电气工程
·
制造技术
✓ 已验证
产品关联
DOI
高影响因子
Reaction Kinetics Mechanisms and Catalysis
·
2026
·
IF 2.1
Liu Chunxiao,Cai Baoli,Yin Wang,Huang Zhixian
In this study, Ethylene glycol monobutyl ether acetate (EBAC) was synthesized via the transesterification between ethylene glycol monobutyl ether (EB) and butyl acetate (BAC) with Amberlyst 15 resin adopted as the catalyst. The influences of ether-ester molar ratio (1:1–1:4), reaction temperature (333.15–373.15 K) and catalyst dosage (2–10 wt%) on the reaction were investigated through experiments. On the basis of kinetic experimental data, the pseudo-homogeneous (P–H) model and Langmuir–Hinshelwood-Hougen-Watson (LHHW) model were constructed and compared. The LHHW model delivered superior fitting performance, with the maximum root-mean-square deviation (RMSD) reaching 0.0118. Fixed-bed reactor simulation was carried out by means of COMSOL Multiphysics software, and the simulation outcomes were verified against experimental results. The average errors of molar fractions for EB and EBAC at the reactor outlet were 0.0331 and 0.0224, which verifies the reliability of the kinetic model. Meanwhile, combined with relevant experiments and characterization results, it is confirmed that the selected catalyst possesses excellent structural stability and recycling potential. On this foundation, a conceptual-design scheme for the continuous reaction-separation process was put forward to separate the azeotrope composed of BAC and n -butanol (BUOH) generated in the transesterification reaction. This research provides new insights and a theoretical foundation for the exploitation of transesterification-based processes for EBAC manufacture.
✓ 已验证
DOI
高影响因子
POLYMER
·
2022
·
IF 4.432
Jie Huan,Jing Li,Yinjia Lan,Sheng Wang,Xiaohong Li,Xiaoming Yang,Huanjun Lu,Yingfeng Tu
We present here the effect of oligo(ethylene glycol) (OEG) segmental length on properties of cyclic oligo(oligoethylene glycol terephthalate)s (COEGTs) and their corresponding polymer counterparts, poly(oligoethylene glycol terephthalate)s (POEGTs). COEGT monomers were synthesized from terephthaloyl chloride with corresponding diethylene glycol , triethylene glycol , and tetraethylene glycol under pseudo-high-dilution conditions. As those large ring cyclic monomers are hard to be polymerized via traditional ring-opening polymerization, a cascade polycondensation-coupling ring-opening polymerization method is utilized to obtain high molecular weight POEGTs. The cascade polymerization mechanism is confirmed by the kinetics study . The structures of COEGTs and POEGTs were well characterized and their properties were studied to reveal the structure-property relationship. With the increment of OEG length in repeating units, the chain flexibility of POEGT and COEGTs is enhanced. As a result, the melting temperatures of COEGTs and glass transition temperatures of POEGTs decrease. On the other hand, the thermal degradation temperature of POEGTs and COEGTs increases due to the enhanced ether fraction and reduced ring strain. Solid-state polymer electrolytes based on POEGTs was prepared by blending with lithium bis(trifluoromethanesulfonyl)imide. The measured ionic conductivity increased with the OEG length in POEGT repeating units. Our results revealed the effect of OEG length on the structure-property relationship in cyclic oligo(ether ester)s and copoly(ether ester)s, providing a facile way to tune their properties.
研究领域:
高分子化学
·
材料科学
✓ 已验证
DOI
高影响因子
RSC Advances
·
2019
·Vol. 9
·期 58
·33941-33948
·
IF 3.049
Qi Qi,Yitong Yao,Xiaoshi Jia,Yuezhong Meng,Ke Zhao,Yutao Jian
To study the effects of polyethylene glycol (PEG) content on the mechanical properties and degradation of silk fibroin, nano-hydroxyapatite, and PEG (SF/nHAP/PEG) electrospun scaffolds, and according to the PEG ratio in the scaffold (SF : nHAP : PEG), test groups were divided as follows: PEG-0 (10 : 2), PEG-0.5 (10 : 2 : 0.5), PEG-1 (10 : 2 : 1), and PEG-2 (10 : 2 : 2). A series of tests to determine the mechanical properties, degradation rates, and osteogenic characteristics was undertaken. PEG facilitated SF degradation (PEG-1 > PEG-0.5 > PEG-0 > PEG-2), and the mass loss of the scaffolds in PEG-1 was more than 30%, while in PEG-2 it was less than 20% after 8 days (P < 0.05). The addition of PEG strengthened the mechanical properties of the scaffold (PEG-1 > PEG-2 > PEG-0.5 > PEG-0), as the Young's modulus increased from 41.72 ± 3.40 MPa for PEG-0 to 76.12 ± 3.73 MPa for PEG-1 (P < 0.05). PEG was favorable for the osteogenic differentiation of BMSCs (PEG-0.5 > PEG-1 > PEG-2 > PEG-0). The enhancements were attributable to the increased hydrophilicity and nHAP dispersion, as well as to the secondary structure transformation of SF. The PEG content was deemed to be optimal when the SF/nHAP/PEG ratio was equal to 10 : 2 : 1.
研究领域:
材料科学
·
生物材料
·
组织工程
✓ 已验证
DOI
PubMed
高影响因子
JOURNAL OF APPLIED POLYMER SCIENCE
·
2013
·Vol. 131
·期 1
·
IF 1.395
Lili Yu,Lin Yao,Jing You,Yihui Guo,Liyan Yang
A crosslinked amphiphilic copolymer [poly(ethylene glycol) (PEG)–poly(methyl methacrylate) (PMMA)–ethylene glycol dimethacrylate (EGDM)] composed of PMMA, PEG, and crosslinking units (EGDM) was synthesized by atom transfer radical polymerization to develop micelles as carriers for hydrophobic drugs. By adjusting the molar ratio of methyl methacrylate and EGDM, three block copolymer samples (P0, P1, and P2) were prepared. The measurement of gel permeation chromatography and 1 H-NMR indicated the formation of crosslinked structures for P1 and P2. Fluorescence spectroscopy measurement indicated that PEG–PMMA–EGDM could self-assemble to form micelles, and the critical micelle concentration values of the crosslinked polymer were lower than those of linear ones. The prepared PEG–PMMA–EGDM micelles were used to load doxorubicin (DOX). The drug-loading efficiencies of P1 and P2 were higher than that of P0 because the crosslinking units enhanced the micelles' stability. With increasing drug-loading contents, DOX release from the micelles in vitro was decreased, and in the crosslinked formulations, the release rate was also slower. An in vitro release study indicated that DOX release from the micelles for the linear samples was faster than that for crosslinked micelles. The drug feeding amount increased and resulted in an increase in the drug-loading content, and the loading efficiency decreased. These PEG–PMMA–EGDM micelles did not show toxicity in vitro and could reduce the cytotoxicity of DOX in the micelles; this suggested that they are good candidates as stable drug carriers. © 2013 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2014 , 131 , 39623.
研究领域:
高分子科学
·
药剂学
·
生物医学工程
✓ 已验证
产品关联
DOI
高影响因子
Materials Science & Engineering C-Materials for Biological Applications
·
2018
·
IF 5.08
Hongchun Li,Yongsheng Niu
A novel amphiphilic block polymer poly(ethylene glycol)-poly(propylene carbonate)-poly(ethylene glycol) (PEG-PPC-PEG) was synthesized via the dicyclohexylcarbodiimide condensation reaction of double PEG-bis-amine and HOOC-PPC-COOH. The obtained copolymer was characterized by NMR to determine its structure. Using the PEG-PPC-PEG as the carrier and using doxorubicin (DOX) as a model drug, DOX-loaded nanoparticles with core shell structure were synthesized by self-assembly in water. The nanoparticles properties such as particle size, drug loading, encapsulation efficiency (EE) and drug release behavior were investigated as a function of the hydrophobic block length of PPC segments and compared with each other. The results showed that the EE was up to 88.8%. Nanoparticles were found to have a certain effect on the controlled release of DOX.
研究领域:
药学
·
材料科学
·
纳米技术
·
药物递送系统
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF POLYMERS AND THE ENVIRONMENT
·
2012
·Vol. 20
·期 2
·528-539
·
IF 1.349
Wang Jiwen,Zhai Wentao,Zheng Wenge
The main purpose of this study is challenging to dramatically improve the toughness of poly(lactic acid) (PLA)/starch by adding poly (ethylene glycol) (PEG) into the composites and grafting PEG molecules onto the surface of starch particles. It was found that the surface grafting of PEG onto starch induced the presence of PEG-rich regions located around the starch particles, caused by migration and aggregation of free PEG molecules. A novel interphase transition layer between PLA and starch was formed, which showed great ability for cavitation and vested large-scaled plastic deformation to PLA matrix. Further mechanical properties tests indicated the formation of interphase layer significantly increase the elongation at break from 10.2 to 254.5%, and notched impact strength from 1.56 to 2.37 kJ/m 2 for PLA/PEG/starch ternary composites. The influence of PEG component, ethanol extraction and annealing was also investigated.
研究领域:
材料科学
·
高分子化学
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）