CHINESE JOURNAL OF ANALYTICAL CHEMISTRY
·
2012
·
IF 0.941
Hong-Wei WU,Mei-Lan CHEN,Dan SHOU,Yan ZHU
A novel method was established for the simultaneous determination of resorcinol and phloroglucinol in environmental water samples by ion chromatography with chemiluminescence detection. Using 50 mM NaOH as eluent, resorcinol and phloroglucinol can be separated well with IonPac AS19 column and determined on the basis of chemiluminescence reaction of luminol and K 4 Fe(CN) 6 in a alkaline medium. The optimal CL conditions were 6.0 × 10 −4 M luminol, 0.1 M K 4 Fe(CN) 6 and 5.5 × 10 −5 M K 3 Fe(CN) 6 . The absence of methanol and acetonitrile in mobile phase made the proposed method more sensitive. Under the optimal conditions, the detection limit (LOD) of resorcinol and phloroglucinol were 4.0 and 4.3 μg L −1 , respectively. The method showed good linearity within the range of 0.05-1.0 mg L −1 . The relative standard deviations (RSD) for 0.1 mg L −1 resorcinol and phloroglucinol standard solutions were 0.9% and 1.1% ( n = 11). The method was successfully applied to the determination of resorcinol and phloroglucinol in environmental water samples.
研究领域:
分析化学
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环境科学
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DOI
高影响因子
ADVANCED FUNCTIONAL MATERIALS
·
2025
·
IF 19
Wenhao Yu,Yaojie Liu,Mo Xian,Ximin Chen,Zongjiang Yu,Long Jiang,Chao Xu
Surface molecular-imprinting is an efficient and eco-friendly route to resource recovery. Yet most studies prioritize template–monomer affinity and seldom integrate radical-polymerization characteristics upfront, risking an affinity–performance gap. Using phloroglucinol (PG) as a model, a 3D “binding energy–SOMO/LUMO gap–steric hindrance” screening framework is established that identifies N-vinylimidazole (VIM) for matrix grafting and 2-(dimethylamino)ethyl methacrylate (DMAEMA) for imprinting. Surface radical polymerization on VIM-grafted chloromethylated polystyrene with DMAEMA (imprinting monomer) and PG (template) affords CMPS-VIM-MIP. The material exhibits an equilibrium adsorption capacity of 118.4 mg g −1 , 2.6 times that of the commercial resin NKA-II (45.5 mg g −1 ). In the fermentation system, the capacity decreases by 19.9% yet remains 4.0 times that of NKA-II. Mechanistic analysis reveals that imidazolium sites induce long-range electrostatic polarization, while multiple hydrogen bonds between the polymer's carbonyl/tertiary-amine groups and the hydroxyl groups of PG, act cooperatively to form high-affinity imprinting cavities. This multidimensional co-screening of functional monomers delivers concurrent gains in adsorption performance and offers a generalizable route for the green recovery of high-value phenolics.
研究领域:
环境化学
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高分子科学
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吸附技术
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绿色资源回收
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分子识别
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DOI
高影响因子
ELECTROPHORESIS
·
2026
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IF 2.6
Zhixu Chen,Biao Sun,Hanlin Zeng,Xinyang Li,Erwin Adams,Xiaoqi Zhang,Zhengjin Jiang,Jincai Wang
Neuraminidase inhibitors (NAIs) are a crucial therapy for combatting the influenza virus. This study employed an at-line nanofractionation technique to precisely localized potential NAIs in the extract of Humulus lupulus L. Twelve potential compounds, mainly phloroglucinol derivatives, were screened and identified. Seven of these compounds were subsequently isolated, purified, and structurally elucidated by NMR. Among them, Compound 5 showed remarkable inhibitory activity against both neuraminidase (NA, IC 50 = 0.8 µM) and the H3N2 influenza virus (EC 50 = 3.8 µM), confirming its potential as a lead compound for anti-influenza development. Compounds 4 and 8 , identified as hitherto uncharacterized phloroglucinol derivatives, also demonstrated significant inhibition against NA and the H3N2 influenza virus. Molecular docking revealed that Compounds 4 and 5 exhibited superior binding affinities compared to oseltamivir, with 4 forming critical hydrogen bonds with acidic residues (Glu119, Glu227, and Asp151) in the “150-cavity,” which significantly enhances its inhibitory potency against NAs.
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DOI
PubMed
高影响因子
JOURNAL OF RADIOANALYTICAL AND NUCLEAR CHEMISTRY
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2018
·Vol. 319
·期 1
·279-288
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IF 1.181
Liu Mouwu,Wang Yanfei,Ma Zhili,Luo Yige
Poly(cyclotriphosphazene-co-phloroglucinol) (PCPP) microspheres, a new solid phase extraction for extracting uranium(VI), synthesized via one-pot precipitation copolymerization. The PCPP microspheres were characterized by FT-IR, SEM/EDS, zeta potential and N 2 adsorption/desorption isotherms. Through the extraction experiment to evaluate the extraction behavior of the PCPP microspheres for uranium(VI). The extractant can achieve the optimal effect under the conditions of contact time with 60 min, pH = 3.5, initial concentration 100 mg L −1 and extractant dosage 0.70 g L −1 . The extraction behavior obeyed with the pseudo second-order model and Langmuir isotherm model.
研究领域:
化学
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环境科学
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产品关联
DOI
高影响因子
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
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2018
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IF 2.88
Mohammed Hassan Ibrahim,Zhonghua Xue,Mahgoub Ibrahim Shinger,Hassan Idris Abdu,Lulu Xiong,Duoliang Shan,Xiaoquan Lu
Immoderate intake of nitrite (NO 2 − ) is deleterious human health and may result in causing dangerous diseases. In this study, nitrite detection system was successfully fabricated based on a unique diazo-coupling reaction of p‑Aminobenzoic acid (PABA) and phloroglucinol (1, 3, 5‑trihydroxybenzene). Upon the presence of NO 2 − in an acid medium, p‑Aminobenzoic acid could not only form diazonium ion easily but also couple with p‑Aminobenzoic acid, and results forming yellow water-soluble azo dye that shows maximum absorption at 434 nm. Under the further accurate determination condition, such as acid concentration, amount of reagents and time required, the naked-eye detection of NO 2 − showed excellent selectivity in compared with some anions. Especially, diazotization and coupling reaction proposed here is very fast and control of pH and temperature are unnecessary. Moreover, the color is stable for several days and Beer's law is obeyed over a wide range. Reliable detection can be made in the range of 0.05 to 1 p.p.m. of nitrite ion. Detection limit was calculated to be 0.024 p.p.m. (0.52 μ M) by UV–visible spectroscopy and 0.05 p.p.m. (1.09 μ M) by naked-eye. By using an electrochemical method, IR, SEM, and 1 HNMR, the sensing mechanism can be easily verified. More importantly the proposed method was successfully applied for the determination of nitrite in a real water sample.
研究领域:
分析化学
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环境科学
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生物医学
✓ 已验证
DOI
高影响因子
ANALYTICA CHIMICA ACTA
·
2016
·
IF 4.712
Shiru Liang,Hongyuan Yan,Jiankun Cao,Yehong Han,Shigang Shen,Ligai Bai
A new molecularly imprinted phloroglucinol–formaldehyde–melamine resin (MIPFMR) was synthesized in a deep eutectic solvent (DES) using phenylephrine as a dummy template. The MIPFMR was used as a solid phase extraction (SPE) sorbent for the selective isolation and recognition of clorprenaline (CLP) and bambuterol (BAM) in urine. Phloroglucinol and melamine were used as double functional monomers that introduced abundant hydrophilic groups (such as hydroxyl groups , imino groups , and ether linkages) into the MIPFMR, making it compatible with aqueous solvents . In addition, the formation of DES by combining the quaternary ammonium salt of choline chloride with ethylene glycol as a hydrogen bond donor was an environmentally safe alternative to toxic organic solvents such as chloroform and dimethylsulfoxide that are typically used in the preparation of most molecularly imprinted polymers (MIPs). Moreover, MIPFMR-based SPE of CLP and BAM in urine resulted in higher recoveries and purer extracts than those obtained by using other SPE materials (e.g., SCX, C 18 , HLB, and non-imprinted phloroglucinol–formaldehyde–melamine resin (NIPFMR)). The optimized MIPFMR–SPE–HPLC–UV method had good linearity (r 2 ≥ 0.9996) ranging from 15.0 to 3000.0 ng mL −1 for CLP and BAM, and the recoveries at three spiked levels ranged from 91.7% to 100.1% with RSDs ≤7.6%. The novel MIPFMR–SPE–HPLC–UV method is simple, selective, and accurate, and can be used for the determination of CLP and BAM in urine samples.
研究领域:
分析化学
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环境科学
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药物分析
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DOI
PubMed
高影响因子
FOOD CHEMISTRY
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2022
·
IF 9.231
Chengcheng Zhai,Mingwei Wang,Yanke Lu,Hongyuan Yan
Polycyclic aromatic hydrocarbons (PAHs) posed a serious threat to food safety and human health due to long-term emission. In this work, a new method was established using phloroglucinol-urotropine porous polymer (PU-PP) in a pipette tip for solid phase extraction (PT-SPE) for the first time and used prior to determination of four PAHs (phenanthrene, anthracene, fluoranthene, and pyrene) in lotus roots. Synthesis of the PU-PP adsorbent was green compared with alternatives; urotropine was used as a cross-linker and ethanol–water as the solvent. PU-PP-based PT-SPE had the advantages of low solvent consumption, good purification, practicability, stability, and low-cost. The proposed pre-purification method offered low limits of detection (0.09–0.28 ng/g) and good recoveries (84.6–114.3 %, RSDs ≤ 5.6 %) for determination of the four PAHs, which were detected at trace concentrations in samples. This new method provides an alternative for monitoring trace pollutants in aquatic plant ingredients.
研究领域:
食品安全
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环境科学
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分析化学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）