CHEMICAL ENGINEERING JOURNAL
·
2026
·
IF 12.5
Jun Geng,Ying Lu,Jingqi Yang,Jiaqi Cai,Yudan Si,JinWei Zhang,Shuxia Liu
A PA-regulated CS/PW 12 interfacial strategy was developed to construct homogeneous POM-based conductive hydrogels. • The CSAWA hydrogel achieved high proton conductivity of 1.05 × 10 −1 S cm −1 at 25 °C and 5.13 × 10 −3 S cm −1 at −40 °C. • CSAWA hydrogel exhibits anti-freezing, adhesive, self-healing, antibacterial, and cytocompatible properties. • CSAWA enables strain sensing, ECG monitoring, and wide-temperature solid-state supercapacitors. The development of flexible wearable sensors and energy storage devices requires materials that integrate stable conductivity, reliable adhesion, good biocompatibility, and cold tolerance. Polyoxometalate (POM)-based proton-conductive hydrogels are promising for both proton transport and electrochemical functionality, yet their low-temperature performance is limited by unstable POM dispersion, weakened interfacial adhesion, and reduced charge transport. Incorporating chitosan (CS) can improve bioadhesion and biocompatibility; however, strong local association between protonated CS chains and anionic POM clusters may promote POM aggregation and network heterogeneity. Here, we designed a multifunctional CS/sulfobetaine methacrylate (SBMA)/acrylic acid (AA)/POM H 3 PW 12 O 40 (PW 12 )/phytic acid (PA) hydrogel (CSAWA hydrogel). Within this network, SBMA promotes hydration, chain flexibility, and proton transport, while AA provides carboxyl groups for reversible hydrogen bonding and network stabilization. PA mediates the local interactions among CS, PW 12 , and the surrounding polymer network, thereby improving PW 12 dispersion, while its multipoint interactions with CS help maintain adhesion at low temperature. Meanwhile, its phosphate groups provide acidic proton sites and hinder free-water crystallization, thereby preserving proton transport under cold conditions. The CSAWA hydrogel exhibited high proton conductivity, excellent stretchability, rapid self-healing ability, stable adhesion, effective antibacterial activity, and good cytocompatibility. Moreover, CSAWA-based wearable strain sensors, electrocardiogram (ECG) electrodes, and flexible solid-state supercapacitors showed reliable performance under low temperatures. This work presents a molecular interaction-regulation strategy for integrating proton conduction, adhesion, cold tolerance, and electrochemical functionality within conductive hydrogels.
✓ 已验证
产品关联
DOI
高影响因子
Nanoscale Horizons
·
2025
·
IF 6.6
Xiao Wan Han,Xu Chen,Tianle Yang,Ying Yi Luo,Rui Xue Liang,San Qi An,Xinli Liu
Cuproptosis has recently received much attention in cancer treatment. However, copper ionophores don’t show the obvious clinical efficacy. Although some Cu-based and copper ionophores-loaded nanomaterials have been applied to induce cuproptosis, it is difficult to achieve the clinical translation limited by the complicated composition, harsh synthesis condition, external stimulus, and potential biotoxicity. Phytic acid, a naturally occurring organic phosphorus carbohydrate, possesses distinct antineoplastic effect on multiply types of cancer and high biocompatibility. Based on metal-phosphonate coordination, a novel Cu-phytic acid nanozyme (denoted as CP) with pH/GSH dual-response was fabricated by a “one-spot” method. CP with three enzyme-mimicking activities enhanced cuproptosis therapy through GSH depletion, reactive oxygen species augment, hypoxia relief and the attenuation of glycolysis. As a proof of concept, Elesclomol (a copper ionophore)-resistant A549 cells were used to investigate CP- induced cuproptosis for inhibition of tumor growth in vitro and in vivo.
研究领域:
生物医学
·
纳米技术
·
肿瘤学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
ANALYTICA CHIMICA ACTA
·
2020
·
IF 5.977
Lili Yang,Hao Wang,Haitao Lü,Ni Hui
A rapid, sensitive and low-fouling sensor for application to detect clinical biomarkers directly in biological media is highly desirable. Herein, we report a versatile strategy to prepare polyaniline (PANI) based conducting polymer hydrogel through the assembly of PANI and phytic acid (PA) by dynamic boronate bond. PANI/PA, a conductive hydrogel with high specific area and multiple pore structures have demonstrated excellent antifouling ability and electrochemical property. The electrochemical biosensors for microRNA can be developed by the immobilization of DNA probes onto PANI/PA interface (microRNA24 is used as a model case), and redox currents of PANI were utilized as the sensing signals to assay DNA/RNA hybridization reaction. Owing to the typical characteristics of PANI/PA hydrogel, the biosensor has shown excellent sensing performances with wide linear range (1.0 fM-1.0 pM), low sensing limit (0.34 fM) and efficient ability to detect microRNA mismatches. Given the facile processability, excellent stability and good antifouling property of the PANI/PA hydrogel, the proposed hydrogel-based biosensor may find broad applications in clinical diagnostics and biomedical devices.
研究领域:
材料科学
·
生物化学
·
分析化学
·
生物医学工程
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF CHEMICAL AND ENGINEERING DATA
·
2018
·
IF 2.196
Hao Lei,Ning Pan,Xiaoqiang Wang,Hao Zou
A novel phytic acid impregnated polyaniline (PA-PANI) was synthesized by a in situ polymerization and supermolecular self-assembly method and has been used as an adsorbent for efficient capture of U(VI) from aqueous solution. The structure and morphology of the adsorbent were well characterized. The influence of different factors such as pH value, ionic strength, contact time, initial U(VI) concentration and temperature on the adsorption of U(VI) onto PA-PANI-3 were carried out by batch adsorption experiments. The results demonstrated an enhanced U(VI) adsorption capacity of 86.6 mg/g for PA-PANI-3, greatly exceeding that of polyaniline (PANI, 8.8 mg/g). The adsorption process follows the pseudo-second-order kinetic and Langmuir isotherm models with the theoretical maximum adsorption capacity of 90.3 mg/g. According to the calculation from the Dubinin–Radushkevich isotherm model equation, it is suggested that the adsorption is mainly a chemical adsorption mechanism. U(VI) is adsorbed on PA-PANI-3 via the phosphoric acid, amine, and imine groups. The U(VI) can be desorbed from the U(VI) adsorbed PA-PANI-3 with a desorption efficiency of 90.8% by using 0.1 mol/L Na2CO3 solution. This study demonstrated that PA-PANI could be used as an efficient adsorbent for removal and recovery of U(VI) from aqueous solution.
研究领域:
材料科学
·
环境科学
✓ 已验证
产品关联
DOI
高影响因子
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
·
2022
·
IF 5.518
Guanfei Zhao,Xihui Fang,Yu Zhang
The flotation of sulfide minerals has been always a problem due to the slime coating of serpentine. In this study, phytic acid (PA) was introduced as a selective depressant to eliminate the adverse effect of serpentine on the flotation of pyrite. Micro-flotation tests showed that the flotation performance of pyrite depressed by serpentine could be regained with the addition of PA. In addition to micro-flotation tests, the action mechanism of PA was systemically investigated based on a series of analyses including zeta potential tests, adsorption measurements, turbidity studies and X-ray photoelectron spectroscopy (XPS) analyses. It was found that PA could chemically react with the active Mg sites and then selectively adsorb onto serpentine surface. In this case, the surface potential of serpentine was shifted from positive to negative at pH 9, thus resulting in the transformation of electrostatic interaction between pyrite and serpentine from electrostatic attraction to electrostatic repulsion. Hence, the slime coating of serpentine on pyrite surface was removed and the adsorption amount of potassium butyl xanthate (PBX) onto pyrite surface was regained. In this way, the adverse effect of serpentine on the flotation of pyrite was eliminated.
研究领域:
矿物加工
·
化学工程
·
材料科学
✓ 已验证
产品关联
DOI
高影响因子
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2023
·
IF 8.2
Qihang Peng,Tianxiang Jin,Chongshi Wang,Yong Qian
Phytic acid-modified carboxymethyl cellulose (CMC-PA) has been investigated as a promising adsorbent for the removal of uranium from aqueous solutions. The synthesis of CMC-PA involves the hydrogen bonding interaction between CMC and PA, resulting in the incorporation of PA groups onto the cellulose backbone. The hydrophilicity , reusability and adsorption capacity of the prepared CMC-PA hydrogel have improved with the increase of PA content. Moreover, the adsorption experiments were conducted by varying parameters such as pH, initial uranium concentration, and contact time. The results showed that CMC-PA exhibited excellent uranium adsorption performance, with a theoretical maximum adsorption capacity of 436 mg/g. In addition, the material exhibits excellent reusability, and the reusability improves with the increase of crosslinking density, indicating that the crosslinking structure of the polymer gel can effectively enhance the structural stability of the material. Furthermore, CMC-PA also exhibits high selective adsorption performance towards uranium ions in the presence of various competing ions. Its high adsorption capacity, reusability, and selectivity make it a promising candidate for high-performance uranium ion adsorbents.
✓ 已验证
DOI
PubMed
高影响因子
ACS Applied Polymer Materials
·
2021
·
IF 4.089
Shuang He,Yu-Yang Gao,Ze-Yong Zhao,Sheng-Chao Huang,Zi-Xun Chen,Cong Deng,Yu-Zhong Wang
Phytic acid and amino acid belonging to the biomass material have a wide range of sources in nature. In this work, three kinds of basic amino acids, which are arginine, lysine, and histidine, were used to prepare different bio-based phytic acid–basic amino acid salts (PaArg, PaLys, and PaHis) via a salt-forming reaction. After the incorporation of PaArg, PaLys, and PaHis into polypropylene (PP), PaArg showed a higher efficiency than PaLys and PaHis in endowing PP with flame retardancy. At 22 wt % PaArg, the limiting oxygen index (LOI) value of functional PP was 26.0%, and its UL-94 rating reached V-0 in the vertical burning test. In the fire hazard test, PaLys showed a higher efficiency than PaArg and PaHis in reducing the fire hazard of PP during burning. The peak value of the heat release rate for PP containing 25 wt % PaLys was decreased by 70.7% compared with that of PP, and its fire growth rate was reduced by 86.9%. Analysis on the fire-safety mechanism revealed that the high char-forming rate and the quality of the residue dominated the superior flame-retardant efficiency of PaArg in UL-94 and LOI tests; high strength of the formed char layer, diluting effect of nonflammable gases, and incomplete combustion action led to the superior efficiency of PaLys in decreasing the fire hazard of PP. This work confirms that fully bio-based phytic acid–basic amino acid salt based on the accurate molecular design may endow PP with fire safety under different burning scenes.
研究领域:
材料科学
·
化学工程
·
燃烧学
✓ 已验证
DOI
高影响因子
FUEL
·
2025
·
IF 7.5
Yuanyuan Li,Xiaoling Xu,Ran Zhang,Xingbao Yang,Kun Jia
Traditional coal mine fire suppression methods face critical limitations, including short-term efficacy, poor penetration in concealed coal seams, and environmental risks from chemical residues. To address these challenges, this study developed a biomaterial-based composite inhibitor integrating physical isolation, free radical quenching, and antioxidant slow release for sustainable prevention of spontaneous coal combustion. A novel antioxidant-loaded composite was synthesized using hollow mesoporous TiO 2 nanoparticles (HM-TiO 2 ) as carriers, which were functionalized via layer-by-layer self-assembly (LBL) of chitosan (CS) and phytic acid (PA) to encapsulate tea polyphenol (TP). This design enables the TP antioxidant activity and low release while leveraging CS/PA’s catalytic char-forming capacity. The chemical composition and micromorphology of the composite were systematically characterized through FTIR, XRD, SEM, and TEM analyses. Programmed temperature oxidation experiments combined with thermogravimetric (TG) and thermogravimetric-Fourier Transform Infrared Spectroscopy (TG-FTIR) measurements were conducted to evaluate inhibition performance by tracking mass loss, characteristic gas emissions, and radical intermediates. Key findings demonstrate that the composite inhibitor: Prolongs coal ignition delay by 48 % compared to untreated coal, attributed to the synergistic barrier effect of the TiO 2 @CS-PA framework and TP’s radical scavenging activity; Reduces CO, CO 2 , CH 4 and H 2 O emissions during low-temperature oxidation; Maintains structural stability above 400 °C, with TiO 2 catalyzing dense char layers to isolate oxygen diffusion. This multifunctional composite overcomes the trade-off between inhibition longevity and environmental compatibility observed in conventional inhibitors (e.g., MgCl 2 , KMnO 4 ), offering a scalable solution for fire prevention in high-level mining areas. The bio-based components (CS, PA, TP) further ensure ecological safety, aligning with green mining initiatives.
✓ 已验证
产品关联
DOI
高影响因子
Soft Matter
·
2022
·Vol. 18
·期 14
·2814-2828
·
IF 4.046
Xian-hui Shao,Xiao Yang,Yue Zhou,Qing-chang Xia,Yun-ping Lu,Xiao Yan,Chen Chen,Ting-ting Zheng,Lin-lin Zhang,Yu-ning Ma,Yu-xia Ma,Shu-zhong Gao
Making a hydrogel-based first-aid bandage with green resources, desirable biocompatibility, universal adhesive properties, low cost and simple production is a long-standing research aspiration. Considering this, three naturally existing organic acids, namely tannic acid, thioctic acid and phytic acid, were used to construct a novel adhesive gel (TATAPA hydrogel) for epidermal tissue bandage applications. This hydrogel could be synthesized under mild conditions with no need for a freeze–thawing shaping procedure, and was transparent, moldable and stretchable with good stability under continuous water immersion. In lap-shear tests, the TATAPA hydrogel could adhere to various hydrophilic and hydrophobic surfaces. Moreover, in the case of skin tissue adhesion, the hydrogel could be easily peeled off from the skin, meeting wearability requirements. Rheological tests showed that the hydrogel possessed thermal sensitive properties derived from multi-supramolecular interactions. The methicillin-resistant Staphylococcus aureus (MRSA)-infected burn wound test demonstrated that the hydrogel had desirable antibacterial activity and was beneficial for wound healing. A femoral artery bleeding assay was also used to reveal that the TATAPA hydrogel could be directly pasted onto the bleeding site for hemostasis. Overall, this hydrogel demonstrates potential as a surgical bioadhesive for a broad range of medical applications.
研究领域:
材料科学
·
生物医学工程
·
伤口护理
·
药剂学
✓ 已验证
DOI
PubMed
高影响因子
LANGMUIR
·
2024
·
IF 3.7
Fashuo Du,Anyao Ma,Wenxiang Wang,Liangjiu Bai,Hou Chen,Donglei Wei,Kun Yin,Lixia Yang,Huawei Yang
Cellulose nanocrystals (CNCs) have garnered significant attention as a modifiable substrate because of their exceptional performances, including remarkable degradability, high tensile strength, high elastic modulus, and biocompatibility. In this article, the successful adsorption of phytic acid (PA) onto the surface of cellulose nanocrystals @polydopamine (CNC@PDA) was achieved. Taking inspiration from mussels, a dopamine self-polymerization reaction was employed to coat the surface of CNCs with PDA. Utilizing Pickering emulsion, the CNC@PDA–PA nanomaterial was obtained by grafting PA onto CNC@PDA. An environmentally friendly hydrogel was prepared through various reversible interactions using poly(acrylic acid) (PAA) and Fe3+ as raw materials with the assistance of CNC@PDA–PA. By multiple hydrogen bonding and metal–ligand coordination, nanocomposite hydrogels exhibit remarkable mechanical properties (the tensile strength and strain were 1.82 MPa and 442.1%, respectively) in addition to spectacular healing abilities (96.6% after 5 h). The study aimed to develop an innovative approach for fabricating nanocomposite hydrogels with exceptional self-healing capabilities.
研究领域:
材料科学
·
生物医学工程
✓ 已验证
产品关联
DOI
PubMed
高影响因子
POLYMER ENGINEERING AND SCIENCE
·
2024
·Vol. 64
·期 8
·3669-3681
·
IF 3.2
Hongzhang Li,Xinhua Liu,Eryan Chi,Guocai Xu
Phytic acid (PA) modified polyacrylonitrile (PAN) nanofiber membranes for heavy metal adsorption were fabricated using electrospinning for the first time, and its mechanical properties and heavy metal adsorption under various conditions were tested. The results demonstrated that PA modification improved the mechanical properties of PAN nanofiber membranes at low modification ratio due to increased intermolecular hydrogen bonds and cross-linking. The highest breaking strength and elongation at break were 70.1% and 31.5% over PAN without modification when the PA:PAN ratio was close to 1:5. The Pb 2+ absorption tests in the water solutions demonstrated that the optimal PA:PAN ratio was 1:1, the optimal temperature was 30°C, and the optimal pH was 7. With the optimal parameters, the adsorption capacity reached the maximum and equilibrium after 4 h. The adsorption capacities increased with higher initial Pb 2+ concentrations. The highest adsorption capacity in this study was approximately 240.1 mg g −1 at the initial Pb 2+ concentration of 750.72 mg L −1 . In addition, after de-adsorption process, the 1:1 PA modified membranes maintained 91.9% re-adsorption capacities compared to primary adsorption. Consequently, the PA-modified PAN nanofiber membranes showed promising potentials of metal ion adsorption in wastewater treatment. Highlights Phytic acid modified polyacrylonitrile nanofiber membranes were fabricated. Low ratio modification improved the mechanical properties. The optimal modification ratio for Pb 2+ adsorption is 1:1. The maximum Pb 2+ adsorption capacity was 240.1 mg g −1 in this study. The membranes maintained 91.9% capacities at re-adsorption tests.
研究领域:
材料科学
·
环境工程
·
化学工程
✓ 已验证
产品关联
DOI
高影响因子
RARE METALS
·
2026
·Vol. 45
·期 5
·e70256
·
IF 12.1
Qiang Miao,Sijun Huang,Zhexing Wang,Jiachen Lv,Huan Li,Ying Wang,Yi Guo,Li Xu
en This link goes to a English section zh This link goes to a Chinese section Selective molecular recognition is central to chemical sensing yet discriminating structurally similar molecules at complex interfaces remains challenging. Traditional strategies based on tuning size, charge, or binding-site chemistry often suffer from limited flexibility. Here, we employ dimensionality engineering of cerium-based metal-organic frameworks (Ce-MOFs), comparing 2D and 3D Ce-MOFs to modulate molecular interactions via spatial conformation matching. Phytic acid (PA), with its distinct 3D inositol hexaphosphate structure, exhibits dimension-dependent interfacial assembly behavior. In 2D Ce-MOF, PA acts as a “molecular bridge” inducing interlayer stacking (∼fivefold thickness increase) and leading to strong noncompetitive inhibition (IC 50 = 0.053 mM) of its hydrolase (phosphatase)-mimetic activity. Conversely, confinement within the large pores (14.42 Å) of 3D Ce-MOF allows partial pore penetration (PA cross section: 10.46 Å) resulting in weak competitive inhibition (IC 50 = 1.7 mM). Spectroscopy ( 31 P NMR, FTIR) and zeta potential testing confirmed analogous PA-Ce coordination modes in Ce-MOFs ruling out chemical disparity as the cause. Density functional theory (DFT) calculations further verified the interlayer bridging in 2D MOF and intrapore confinement in 3D MOF as distinct adsorption modes. This fundamental difference—interlayer stacking versus confined penetration driven by dimensionality engineering creates a unique “dimensional fingerprint” for PA. Leveraging this orthogonal response (noncompetitive vs. competitive inhibition), we demonstrate a sensing strategy for selective PA identification. This work establishes dimensionality engineering as a powerful paradigm for rational interface design and selective recognition based on analyte spatial architecture. 摘要 en This link goes to a English section zh This link goes to a Chinese section 选择性分子识别是化学传感的核心,但在复杂界面上实现对结构相似分子的精准区分仍具有挑战性。传统通过调整尺寸、电荷或结合位点化学性质的策略往往灵活性不足。本研究提出一种基于铈基金属有机框架(Ce-MOFs)的维度设计方法,通过构建二维与三维Ce-MOFs,并利用空间构型匹配调控其与植酸(PA)的相互作用。PA具有独特的三维肌醇六磷酸酯结构,因而呈现出显著的维度依赖界面组装行为: 在二维Ce-MOF中,PA作为“分子桥”诱导层间堆叠(厚度增加约5倍),从而对其水解酶活性产生强烈的非竞争性抑制; 而在具有大孔道(14.42 Å)的三维Ce-MOF中,PA(横截面约10.46 Å)可部分进入孔道,仅引起较弱的竞争性抑制。 31 P 核磁共振(NMR)、傅里叶变换红外光谱(FTIR)以及Zeta电位结果表明,两种Ce-MOFs中的PA-Ce配位方式相近,排除了配位化学差异导致响应分化的可能。密度泛函理论(DFT)计算进一步验证了两种截然不同的吸附模式: 二维MOF中的层间桥连与三维MOF中的孔内限域。这种由维度设计驱动的根本差异——层间堆叠与限域渗透,赋予PA独特的“维度指纹”。基于这种正交抑制响应(非竞争性 versus 竞争性),我们构建了用于PA选择性识别的传感策略。该研究确立了维度设计作为一种通用范式,可用于基于分析物空间结构的理性界面设计和选择性识别。
✓ 已验证
DOI
高影响因子
危险品化学品经营许可证（带存储）