JOURNAL OF CONTROLLED RELEASE
·
2023
·
IF 10.8
Youtao Xin,Yunjian Yu,Meihui Su,Xiaohui Li,Mahmoud Elsabahy,Hui Gao
The naturally evolved and intestinal pathogenic Fusobacterium nucleatum ( Fn )-induced drug resistance profoundly impaired the efficacy of chemotherapy against colorectal cancer (CRC). Alternative treatment modalities against Fn -associated CRC are desperately needed. Herein, we engineer an in situ-activated anti-tumor and antibacterial nanoplatform (Cu 2 O/ [email protected] ) to allow photoacoustic (PA) imaging-guided photothermal and NO gas combinatorial therapy for enhanced Fn -associated CRC treatment. The nanoplatform is constructed by loading cuprous oxide (Cu 2 O) and nitric oxide (NO) donor (BNN6) into dextran-decorated mesoporous silica nanoparticles (MSN), which is finally surface-functionalized with dextran via dynamic boronate linkage. Cu 2 O can be sulfuretted in situ by endogenous hydrogen sulfide overexpressed in CRC to produce copper sulfide with remarkable PA and photothermal properties, enabling the generation of NO from BNN6 under 808 nm laser irradiation, which is eventually triggered to release by multiple biological cues in the tumor microenvironment . Cu 2 O/ [email protected] exhibits superior biocompatibility , as well as H 2 S-triggered near-infrared-controlled antibacterial and anti-tumor performance in vitro and in vivo via photothermal and NO gas combination therapy. Furthermore, Cu 2 O/ [email protected] provokes systemic immune responses, thereby promoting anti-tumor efficacy. This study provides a conbinational strategy to effectively inhibit tumors and intratumor pathogens for enhanced CRC treatment.
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高影响因子
Catalysts
·
2016
·Vol. 6
·期 8
·112
·
IF 2.964
Xiaobo Wang,Lei Zhang,Shiguo Wu,Weixin Zou,Shuohan Yu,Ye Shao,Lin Dong
A series of Fe–Ce–Ti catalysts were prepared via co-precipitation method to investigate the effect of doping Ce into Fe–Ti catalysts for selective catalytic reduction of NO with NH3. The NO conversion over Fe–Ce–Ti catalysts was considerably improved after Ce doping compared to that of Fe–Ti catalysts. The Fe(0.2)–Ce(0.4)–Ti catalysts exhibited superior catalytic activity to that of Fe(0.2)–Ti catalysts. The obtained catalysts were characterized by N2adsorption (BET), X-ray diffraction (XRD), temperature programmed reduction (H2-TPR), temperature programmed desorption (NH3-TPD), Fourier transform infrared (FT-IR) spectrophotometry, thermogravimetric analysis (TGA), and X-ray photoelectron spectroscopy (XPS). The data showed that the introduction of Ce results in higher surface area and better dispersion of active components on the catalyst surface and enhances the amount of surface acid sites. The interactions between Fe and Ce species were found to improve the redox ability of the catalyst, which promotes catalytic performance at low temperature. The XPS results revealed that Fe3+/Fe2+and Ce4+/Ce3+coexisted on the catalyst surface and that Ti was in 4+ oxidation state on catalyst surface. Ce doping increased the atomic ratio of Fe/Ti and Ce/Ti and enhanced the surface adsorbed oxygen species. In addition, Fe(0.2)–Ce(0.4)–Ti catalyst also showed better tolerance to H2O and SO2and up to 92% NO conversion at 270 °C with 200 ppm SO2added over 25 h, which suggests that it is a promising industrial catalyst for mid-low temperature NH3–selective catalytic reduction (SCR) reaction.Keywords:SCR;denitration;catalytic activity;synergistic effect;SO2resistance
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Frontiers of Environmental Science & Engineering
·
2023
·Vol. 17
·期 9
·1-12
·
IF 6.4
Ju Tongyao,Han Siyu,Meng Fanzhi,Lin Li,Li Jinglin,Chen Kailun,Jiang Jianguo
Ordered mesoporous silica materials exhibit enormous potential in industrial production. Since coal fly ash (CFA) is abundant in Si, it has become a green and promising way to utilize CFA by synthesizing porous silica materials. However, the stable crystalline structure of CFA limits the extraction of Si, and the residue is generated during the process of extracting Si. In this work, we proposed a no-residue method to synthesize ordered mesoporous silica out of CFA. Sodium carbonate (Na 2 CO 3 ) was used to reconstruct the crystals of the CFA, and the calcined mixture then directly reacted with the precipitators. This method combined the process of Si extraction and porous material synthesis. In this method, no residue was generated and the silicon in both amorphous and crystalline phases of CFA was fully utilized. By this method, the extraction efficiency of Si was increased from 31.75% to nearly 100%. The as-synthesized mesoporous silica had a highly-ordered pore structure with a space group of la-3d , a surface area of 663.87 m 2 /g, a pore volume of 0.41 cm 3 /g, and an average pore diameter of 2.73 nm. The mechanism of crystalline transformation and material structure formation were systematically studied. This method provides a new idea to dispose of CFA and synthesize porous silica materials.
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KOREAN JOURNAL OF CHEMICAL ENGINEERING
·
2016
·Vol. 33
·期 12
·3407-3416
·
IF 1.408
Wu Bo,Xiong Yuanquan,Ru Jinbo,Feng Hao
A novel NO removal system is designed, where NO is initially oxidized by •OH radicals from the decomposition of hydrogen peroxide (H 2 O 2 ) over hematite and then absorbed by ammonium-based solution. According to the high performance liquid chromatography (HPLC) profile and the isopropanol injection experiments, the •OH radicals are proved to play a critical role in NO removal. The NO removal efficiency primarily depends on H 2 O 2 concentration, gas hourly space velocity (GHSV), H 2 O 2 feeding rate and reaction temperature, while the flue gas temperature slightly affects the NO removal efficiency. The low H 2 O 2 consumption makes this system a promising technique in NO removal process using wet-method. The evolution of catalyst in reaction is analyzed by scanning electron microscopy (SEM), energy dispersive X-ray spectrometry (EDS), Fourier Transform infrared spectroscopy (FTIR) and X-ray diffraction (XRD). The nitrite ion and nitrate ion in aqueous solution are detected by the continuous phase flow analyzer. Finally, the macrokinetic parameters of the NO oxidation are obtained by using the initial rate method.
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CHEMOSPHERE
·
2022
·
IF 8.943
Cheng Cheng,Dongyun Chen,Najun Li,Hua Li,Qingfeng Xu,Jinhui He,Jianmei Lu
This paper reports the application of NH 2 -MIL-125(Ti) modified carbon nitride C v -C 3 N 4 with carbon vacancies in the removal of NO. We performed a series of characterizations of the complex and compared various ratios with the individual components. The results of UV spectrum analysis show that the composite's range of light absorption expanded due to the modification of Ti metal–organic framework. Furthermore, the results of photocurrent and electrical impedance indicate the compound has a better ability to generate and transfer electrons . The increase in the compound's NO removal efficiency (up to 63%) indicates that MOF has a positive effect on C v -C 3 N 4 modification—a good method for photocatalysis . Moreover, the compound can promote photocatalysis in a favorable direction.
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高影响因子
ACS Omega
·
2025
·
IF 4.3
Weiwei Kong,Shule Zhang,Qin Zhong
Developing facile TiO2 preparation methods is crucial for advancing the industrial implementation of a catalytic peroxone process for NO oxidation. In this study, three types of precursors, including titanium butoxide (Ti-BO), metatitanic acid (Ti-MTA), and titanyl sulfate (Ti-TOS), were used to synthesize TiO2. Remarkably, Ti-TOS and Ti-MTA exhibited enhanced activity compared to that of Ti-BO, with 93 and 87% NO oxidation efficiency (373 K, O3/NO = 0.4, H2O2/NO = 1.2, GHSV = 1.2 × 105 h–1), which is higher than that of Ti-BO (78%). Further investigations revealed that residual sulfate groups (SO42–) from precursors enhance Lewis acidity by withdrawing electrons from the Ti4+ sites, thereby facilitating H2O2 deprotonation and Ti-OOH formation. This accelerates radical generation for NO oxidation while inhibiting nitrate accumulation and weakening NO adsorption to optimize reaction kinetics. In addition, sulfates also inhibit the accumulation of oxidation product nitrates on the catalyst surface, thereby improving catalytic stability. This work reveals the promotion mechanism of SO42– on the catalytic peroxone process from multiple perspectives.
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高影响因子
ENVIRONMENTAL RESEARCH
·
2025
·
IF 7.7
Huasheng Wang,Shuang Deng,Hongyun Hu,Can Fang,Guangqian Luo,Ze Wang,Songgeng Li
Excessive ClO 2 tends to be produced and escape, causing secondary pollution when wet oxidation of NO with NaClO 2 is conducted under acidic conditions. NaClO 2 alkaline oxidation has accordingly received a wide attention. In this work, NaClO 2 alkaline oxidation of NO has been systematically studied in a self-built spray tower. Focus has been placed on the effects of acidic components contained in flue gas such as CO 2 , HCl and SO 2 . ClO 2 and HClO 2 are considered more effective for NO oxidation, which tend to be produced in an acidic environment. HCO 3 − has a relatively higher hydrolysis coefficient than ClO 2 − , leading to more HClO 2 formation. Similarity is found with HCl although the effect is not as significant as CO 2 due to its low concentration in flue gas. SO 2 exhibits a negative effect on NO removal since HClO 2 can be consumed by SO 2 . Nearly 100 % NO removal efficiency can be achieved although there is an initial time delay necessary for the neutralization of alkaline environment. A similar performance has been observed for HCl. On the contrary, SO 2 exhibits a negative effect on NO removal due to the competition with NO in the consumption of NaClO 2 . Additives such as NaClO and CTAC were also used to enhance NaClO 2 alkaline oxidation performance. Interesting to note that CTAC can nearly eliminate the time delay by intensifying the gas-liquid mass transfer.
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Materials Today Communications
·
2025
·
IF 4.5
Jinzhao Shu,Xueyi Dong,Yuqi Zhang,Zhenzhen Pan,Tianyu Lu,Shijun Kang,Qianwei Liu,Zhiguo Hou,Sen Wang,Bin Yang
The growing danger of bacterial infections has resulted in an urgent need for developing new antibacterial approaches. In this study, cellulose nanofiber-copper sulfide (CNF-CuS), calcium peroxide (CaO 2 ), and L-arginine (LA) were incorporated into polyvinyl alcohol (PVA) and chitosan (CS) hydrogels to fabricate a multifunctional PVA/CS/CNF-CuS/CaO 2 /LA composite hydrogel with near-infrared (NIR)-activated photothermal, photodynamic, and gas therapies. Antibacterial tests on PVA/CS/CNF-CuS/CaO 2 /LA showed that, after a 10-minute NIR irradiation period, the hydrogel achieved antibacterial rates of 99.3% against E. coli and 99.7% against S. aureus. The marked improvement in bactericidal performance can be attributed to the synergistic interaction of elevated temperature, reactive oxygen species (ROS), and nitric oxide (NO). Given the effective antibacterial property of the PVA/CS/CNF-CuS/ CaO 2 /LA hydrogel, this study offers new insights into the design of composite hydrogels for wound healing and wound dressing applications.
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PHYSICA SCRIPTA
·
2022
·Vol. 98
·期 1
·015012
·
IF 3.081
Juncheng Zhou,Xinyue Huang,Wenlin Feng
A Michelson interferometric carbon monoxide (CO) fiber-optic sensor based on Co/Ni-MOF-74 is proposed and fabricated. The bimetallic-ion-coordination MOFs material Co/Ni-MOF-74 was prepared by solvothermal method. Through XRD and XPS characterizations, the results show that Co/Ni-MOF-74 and Ni-MOF-74 have the same crystal structure. Co/Ni-MOF-74 has a good adsorption effect on CO, and it is integrated into the optical fiber sensing structure for CO detection. In the CO concentration range of 0–35 ppm, the sensitivity and linearity are 0.022 35 dB/ppm and 0.999 36, respectively. The detection limit of the sensor is about 1.990 46 ppm. The presented fiber-optic sensor has excellent selectivity, resistance to temperature interference and good time stability, and it is expected to be applied to the detection of trace CO.
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CHEMICAL ENGINEERING JOURNAL
·
2021
·
IF 13.273
Bingke Xie,Dongyun Chen,Najun Li,Qingfeng Xu,Hua Li,Jinghui He,Jianmei Lu
Previously, many methods have been used to reduce NOx pollution. Semiconductor photocatalytic oxidation technology has been widely used among those methods because of its environmental friendliness, high efficiency, and simple implementation. Hybrid halide perovskites with exceptional optical properties prove to be promising photocatalysis material; however, their high surface energy, unpaired bonds, and instability are obstacles to large-scale application. In this work, FAPbBr 3 /g-C 3 N 4 heterostructures were successfully synthesized by growing FAPbBr 3 nanocrystals on 2D g-C 3 N 4 nanosheets. Compared with the pristine elements, FAPbBr 3 /g-C 3 N 4 composites show significant NO removal efficiencies under 600 ppb concentration at room temperature. The high performance could be attributed to the formation of a type-II heterojunction and accelerated the separation and transfer of electrons and holes. Furthermore, cycling experiments and XRD results verify that the FAPbBr 3 /g-C 3 N 4 heterojunction owns good stability. Thus, this work not only shows the great potential prospect of halide perovskite for the photocatalysis field, but also demonstrate its promise in solving energy issues and environment science.
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高影响因子
FUEL
·
2021
·
IF 6.609
Zhanzhi Ge,Yuesong Shen,Sasa Gu
The catalyst for selective catalytic reduction of NO x at high temperatures is significantly demanded by current gas-fired exhaust purification. In this work, the complex oxides composed of two different structures of ZrO 2 -WO 3 and WO 3 /ZrO 2 with zirconium as the main component were prepared for NH 3 -SCR of NO at high temperatures by blending method and equal volume impregnation method, respectively. Combined with XRD, NH 3 -TPD, FE-SEM, BET and in situ DRIFTS characterization, the effects of component optimization of two kinds of ZrO 2 and WO 3 complex oxides on the performance for NH 3 -SCR of NO were mainly studied. The optimal compatibility of ZrO 2 and WO 3 complex oxides was determined, and the corresponding N 2 selectivity and anti-interference ability of water vapor and SO 2 were further investigated. Results showed that the performance of ZrO 2 -WO 3 prepared by blending method for NH 3 -SCR of NO was significantly better than that of WO 3 /ZrO 2 prepared by impregnation method. The ZrO 2 -WO 3 containing 20% WO 3 has the best performance in NH 3 -SCR of NO with NO conversion higher than 90% and N 2 selectivity higher than 90% at 450–650 °C, and the performance was not affected by SO 2 , slightly affected by competitive adsorption of water vapor at 450 °C and not disturbed by water vapor above 500 °C. Further investigation showed that the NH 3 -SCR of NO over the ZrO 2 -WO 3 reaction followed both L-H and E-R mechanisms. Characterization analysis revealed that ZrO 2 -WO 3 has finer microscopic particles, larger specific surface area, higher acid amount and stronger acid strength than WO 3 /ZrO 2 .
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JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
·
2025
·
IF 6.2
Yongjia Cheng,Yao Chen,Jianjun Liu,Dongyang Li,Juan Zhang,Chaojie Li,Wen Yang,Zhiwei Lei
Plants release a variety of defensive volatiles in response to biotic stress. The present study examined interactions between Colletotrichum fructicola and the defense volatiles induced by this fungal species in the tea cultivar “Qiancha No. 1”. Analysis of the volatiles emitted from C. fructicola-infected leaves of “Qiancha No. 1” revealed that four volatiles showed a relative content increase of more than 2%. Fungicidal activity assays demonstrated that decanal exhibited the strongest antifungal activity among the four volatiles. Further physiological experiments demonstrated that the antifungal mechanism of decanal was associated with disruption of the cell wall and the membrane. Transcriptome analysis revealed that the genes encoding Chitinase 1, chitin synthase 1, and endochitinase42 were identified as potential targets that may be involved in cell wall degradation by decanal. Additionally, genes encoding cytochrome P450-DIT2 and multidrug resistance protein fer6 were identified as potential targets that may be associated with membrane damage. This study is the first to demonstrate that decanal acts as a direct defense volatile in the interaction between C. fructicola and “Qiancha No. 1,” highlighting its potential as an effective antifungal agent.
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