Food Bioscience
·
2026
·
IF 6.2
Zhongqin Li,Jiazhen Shi,Yinghua Song,Yue Tang,Lian Xia,Yuangen Wu
Butylated hydroxyanisole (BHA) is a synthetic phenolic antioxidant widely used in edible oils and fat-containing foods. Excessive BHA poses significant risks to human health, thus making rapid and sensitive detection of BHA crucial for health protection. Herein, the Ag 2 CO 3 nanozyme was prepared by the simple precipitation method, which exhibits both laccase-mimic and oxidase-mimic activities. It was found that the oxidase-mimic activity of Ag 2 CO 3 facilitated the conversion of TMB to its blue oxidized form (oxTMB), and subsequent addition of BHA resulted in the formation of a characteristic purple adduct. Additionally, BHA effectively suppressed the laccase-mimic activity of the Ag 2 CO 3 nanozymes. Therefore, a novel colorimetric sensor was constructed using the dual-enzyme-mimic activities as a sensing signal for rapidly detecting BHA in edible oil. The colorimetric sensor achieves limits of detection (LOD) for BHA as low as 1.1 μM in the laccase-mimic channel and 0.08 mM in the oxidase-mimic channel, both of which are substantially lower than the maximum permissible BHA level in edible oils stipulated in Chinese National Food Safety Standard GB 2760. The sensor developed in this work shows great promise for application in the field of edible oil detection.
✓ 已验证
产品关联
DOI
高影响因子
FOOD RESEARCH INTERNATIONAL
·
2026
·
IF 8.8
Lingjin Li,Mengyuan Qin,Zhiqiang Xu,Yuanteng Xu,Yan Hong,Li Cheng,Zhengbiao Gu
The esterase-mediated esterolysis is the key for specific butyrate production. • Carboxylesterase assay verified the involvement of esterases during the fermentation. • The classical metabolic pathway for nonspecific butyrate production is altered. Butyrylated starch is a special type-4 resistant starch with butyrate-carrying attribute. In this study, the unique butyrate-producing capability of butyrylated starch was deeply investigated by focusing on its specific and nonspecific butyrate-producing pathways, respectively, using specially designed substrates as controls. In vitro fermentation studies revealed that butyrylated and isobutyrylated starches generated high levels of butyrate and isobutyrate, respectively, highlighting the role of butyryl group metabolism in the specificity of butyrate production. Carboxylesterase assays have demonstrated that butyryl group metabolism is primarily facilitated by carbohydrate esterases expressed in the gut microbiota. Combined with 16S rRNA sequencing and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analysis, it was found that butyrylated starch fermentation did not significantly enhance traditional butyrate synthesis pathways but modified the balance between the butyryl-CoA:acetyl-CoA transferase and butyrate kinase pathways by altering the gut microbiota composition, specifically by upregulating the relative abundance of indicator species such as Bacteroides , the Lachnospiraceae_NK4A136_group , and Parabacteroides . These insights offer theoretical guidance for designing butyrylated starch structures and regulating intestinal health. Download: Download high-res image (169KB) Download: Download full-size image
✓ 已验证
产品关联
DOI
高影响因子
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2026
·
IF 8.7
Ruimin Wang,Changkun Ding,Yu Zhang,Jing Li,Yutong Liu
Collagen is an ideal raw material for biological fibers, yet achieving long-range structural order and the resultant high-strength fibers without toxic crosslinkers remains a major challenge. This work integrates ultrasonic fragmentation with dialysis concentration to induce a stable lyotropic liquid crystalline (LC) collagen dope at a concentration as low as 3.3%, which is significantly lower than previously reported. Ultrasonic treatment reduced collagen fragment length to 10–30 nm, lowering steric hindrance and enhancing molecular mobility, thereby promoting nematic LC formation. Rheological analysis revealed that at 3.7%, the spinning dope exhibited a characteristic viscosity plateau in the low shear rate range of 1–5 s −1 , indicating shear-induced alignment of nematic LC domains, which defines the optimal spinning window. Using 4.0% LC dope and an optimized ethanol flow rate of 0.30 mL/min in microfluidic spinning process, the resultant collagen fibers achieved a high tensile strength of 2.21 cN/dtex and a thermal denaturation temperature of 120.8 °C. Increasing the spinning dope concentration progressively reduced lateral molecular packing distance, transformed the fiber surface from grooved to smooth, and enhanced thermal stability. This study establishes a rational, crosslinker-free strategy to fabricate high-performance pure collagen fibers with superior mechanical and thermal properties, providing critical theoretical and technical support for their application in absorbable surgical sutures and regenerative medicine. Download: Download high-res image (219KB) Download: Download full-size image
✓ 已验证
产品关联
DOI
高影响因子
SEPARATION AND PURIFICATION TECHNOLOGY
·
2026
·
IF 9.1
Wei Sun,Yingxue Zhang,Zhi Zeng,Najun Li,Qingfeng Xu,Hua Li,Dongyun Chen,Jianmei Lu
The trade-off between permeability and selectivity is a longstanding challenge in nanofiltration membranes that critically limits their practical performance in dye/salt separation. In this work, we present the rational design and fabrication of a series of alkoxy side chain–functionalized covalent organic polymer (COP) thin-film composite membranes (Bth-PEOx) on polyacrylonitrile (PAN) ultrafiltration supports via interfacial polymerization. The resulting membranes enable precise modulation of the nanoscale transport microenvironment—specifically, pore size distribution and surface hydrophilicity—through controlled incorporation of alkoxy side chains of varying length. The optimized Bth-PEO2 membrane achieves highly efficient dye/salt separation in Congo red (CR)/NaCl mixtures, delivering a high water permeance of 45.6 L m −2 h −1 bar −1 , >99% CR rejection, minimal NaCl rejection (6.23%), and an exceptional CR/NaCl separation factor of 117. In addition, the Bth-PEOx membranes exhibit outstanding chemical robustness across extreme pH conditions, superior mechanical resistance to hydraulic compaction, and stable performance during continuous filtration processes. This side chain engineering strategy overcomes the classic permeability–selectivity trade-off by enabling simultaneous improvement of both permeability and selectivity, thereby establishing a scalable, structure–property–guided design paradigm for energy-efficient dye/salt separation and advancing the practical treatment and resource recovery from high-salinity textile wastewater.
✓ 已验证
产品关联
DOI
高影响因子
Frontiers in Pharmacology
·
2026
·
IF 5.4
Nan Hu,Minyan Qian,Yanru Liu,Zhenwei Jiang,Caomei Xu,Wenting Zhang,Jingting Jiang
Backgroud Immunosuppressant tacrolimus (TAC) induces glucose metabolism disorder and diabetes mellitus (DM) closely associated with intestinal microbiota dysbiosis and reduced bile acid levels, and this study aimed to explore the ameliorative effect and underlying mechanism of hyodeoxycholic acid (HDCA) on TAC-induced DM in rat models. Methods We first verified the critical role of intestinal microbiota and bile acids in the pathogenesis of TAC-induced DM via antibiotic-induced gut microbiota depletion, then orally administered HDCA (100 mg/kg) to TAC-induced diabetic rats to evaluate its protective efficacy, detecting glycolipid metabolism indices, targeted bile acid omics, FXR/TGR5 protein expression, serum and ileal GLP/FGF15 levels, and mRNA levels of key metabolic genes including Cyp7a1, Cyp27a1, Cyp7b1, Cyp8b1, Fgfr4, Creb1 and Ppargc1a . Results Antibiotic treatment significantly reduced BSH-active gut microbiota such as Bacteroides and Lactobacillus , disrupting the serum bile acid pool and exacerbating diabetic symptoms by altering the gut microbiota-bile acid axis; while HDCA administration markedly improved glucose tolerance and reshaped bile acid profiles in TAC-induced diabetic rats, specifically lowering serum and fecal 12-OH/Non-12-OH BAs ratio via downregulating hepatic Cyp7a1 and upregulating hepatic Cyp8b1 expression. HDCA also suppressed enteroendocrine cell-derived GLP-1 secretion, decreased serum and ileal FGF15 levels, and reduced the expression of ileal FXR as well as hepatic Creb1 and Ppargc1a. Conclusions Collectively, HDCA exerts a significant ameliorative effect on TACinduced DM by regulating metabolic enzymes and altering bile acid profiles, with the core mechanism involving inhibited enterohepatic FXR-FGF15 axis, increased GLP-1 secretion and suppressed hepatic gluconeogenesis, all of which play key regulatory roles in this protective process.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Foods
·
2026
·Vol. 15
·期 16
·2830
·
IF 6
Haoyue Wu,Yi Zhou,Huaxing Xu,Zhaoming Wang,Xingguang Chen,Hui Zhou
Fresh pork remains susceptible to psychrotrophic spoilage during superchilled storage. Although oregano essential oil (OEO), nisin, and active absorbent pads have each been studied, their effects on spoilage-community proliferation and concurrent quality loss remain poorly resolved. Here, we coupled longitudinal 16S rRNA gene profiling with conventional microbiological and quality measurements to evaluate a poly(vinyl alcohol)/soy protein isolate pad containing OEO-loaded soluble soybean polysaccharide-nisin nanoparticles (PS-NPs). Pork was stored at −1 °C for 24 days without a pad (CK), with a nanoparticle-free pad (PS), or with PS-NPs. Bacterial communities in CK and PS-NPs were profiled alongside total viable count, TVB-N, TBARS, protein carbonyls, color, water-holding capacity, and sensory quality. Compared with CK, PS-NPs slowed the increase in viable counts and delayed physicochemical and sensory deterioration. On day 24,Pseudomonasrelative abundance was 39.48% with PS-NPs and 51.02% in CK. TBARS and protein carbonyl contents were 36.96% and 19.44% lower than CK, respectively, while cooking loss was 28.49% versus 32.18%. Among the evaluated taxon-quality pairs,Pseudomonas psychrophilashowed the strongest positive association with protein carbonyl content. Unlike earlier performance-focused studies, this work links packaging-associated community shifts with concurrent chemical, physical, and sensory changes under superchilling. The findings support PS-NPs as a preservation strategy.
✓ 已验证
产品关联
DOI
高影响因子
Journal of Environmental Chemical Engineering
·
2026
·Vol. 14
·期 5
·124480
·
IF 7.5
Lucheng Li,Ziwenqi Yang,Zehua Zhu,Yuan Han
Excessive phosphorus input drives eutrophication, threatening aquatic ecosystems and water security. However, efficient phosphorus removal and facile adsorbent recovery remain key challenges in wastewater treatment. To remove phosphorus from water while efficiently recovering adsorbents, this study proposes an innovative chitosan-based adsorption dynamic membrane (ADM) system, aiming to achieve simultaneous phosphorus removal and adsorbent recovery, thereby integrating environmental protection with resource recovery. In this study, system performance was enhanced through the optimization of key operational parameters. The results showed that a higher Ca-PAC-CTS concentration increased filtration resistance, accelerated dynamic membrane formation, and improved adsorbent recovery efficiency. Increasing the flow rate facilitated the rapid development of transmembrane pressure and reduced effluent turbidity, thereby contributing to more effective pollutant removal. The optimal operating conditions were determined as a flow rate of 4.8 L/h, a Ca-PAC-CTS concentration of 1.0 g/L, and a hydraulic retention time of 5 min, under which phosphorus removal and adsorbent recovery efficiencies both exceeded 80%. Overall, this study highlights the potential of ADM systems for efficient phosphorus capture and adsorbent recovery, providing support for the development of sustainable and low-carbon technologies in wastewater treatment.
✓ 已验证
产品关联
DOI
高影响因子
iScience
·
2026
·Vol. 29
·期 8
·
IF 4.5
Bangyu Liu,Lian Weng,Gaocheng Zhan,Jiawei Cong,Gongwei Hu,Yiman Liu,Min Liu
Antibiotic contamination in aquatic environments threatens ecosystem health and water security; yet, efficient, recyclable, and environmentally benign removal remains challenging. Here, a magnetically actuated miniature bamboo-fiber robot (MBFR), functionalized with a porous chitin foam, is demonstrated for antibiotic removal from complex water matrices. Bamboo and chitin afford biodegradability and facile fabrication, while Fe 3 O 4 nanoparticles enable fuel-free magnetic actuation, directional propulsion, and magnetic retrieval. The chitin foam provides abundant binding sites for broad-spectrum antibiotic capture through cooperative noncovalent interactions. Magnetic actuation accelerates interfacial mass transfer, with maximum adsorption capacities of 435.60 mg/g for norfloxacin (NOR) and 391.69 mg/g for oxytetracycline (OTC). After 20 adsorption-desorption cycles in natural-water matrices, MBFRs retained over 90% NOR removal and remained effective under representative matrix interferences. This work may open up prospects for functional biomass-derived robots in the active and recyclable remediation of antibiotic-contaminated waters.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
ACS Photonics
·
2026
·
IF 6
Li Guifeng,Tan Xiaotian,Wang Guoquan,Peng Yunli,Liu Yuliang,Li Zhonghao,Cai Zhihan,Yang Xi,Gong Yuan,Gong Chaoyang,Zhu Tao
Direct observation of individual
biomolecular events offers mechanistic
insights into biological processes and provides a powerful tool for
early disease diagnosis. However, the fundamental scale mismatch between optical
wavelengths and molecules restricts the application of
label-free techniques, leading to a poor signal-to-noise ratio (SNR).
Here, we propose a high-contrast, label-free approach based on interferometric
imaging, utilizing the strong evanescent field supported on a microfiber
surface to provide near-field illumination. We observed unique interference
patterns generated by in-plane scattering from natural defects, which
enabled the high-contrast detection of localized phase changes induced
by single molecules. The results indicate an approximately 38 dB enhancement
in the SNR over the conventional fluorescence methods without employing
any plasmonic or microcavity-based amplification techniques. This
approach was further applied to track molecular dynamics, capturing
both the conformational transition and binding behaviors of individual
protein molecules. Meanwhile, the stimulus response of single molecules
to acoustic waves was investigated, demonstrating the ultimate miniaturization
of an acoustic sensor at the single-molecule scale. By enabling direct
observation of molecular dynamics and mechanical responses at the
single-molecule level, this approach provides a versatile platform
for probing fundamental biological processes and developing ultrasensitive
biosensors. Moreover, this approach lays the foundation for coupling
optical and acoustic waves on the molecular scale, opening new avenues
for next-generation single-molecule diagnostics and molecular physics
studies.
✓ 已验证
产品关联
DOI
高影响因子
Nano Energy
·
2026
·
IF 16.7
Junyi Cai,Jialu Li,Xingchi Wang,Qi Tang,Ziao Xu,Faqiang Wang,Jianyong Yu,Bin Ding,Zhaoling Li
CNFs-induced interfacial hydration regulation enables highly oriented graphene-sheet assembly. • Free-standing graphene sheets achieve a high Herman’s orientation factor ( f ) of 0.83. • Superior mechanical strength and electrical conductivity are simultaneously realized. • Exceptional mechanical durability enables 91.6% capacitance retention after 10,000 bends. Increasing the mechanical stability and in-plane electrical conductivity of free-standing graphene sheets is a critical step toward the development of next-generation electronic devices. However, macroscopic defects (nanoplatelet folding, structural collapse, and interlayer misalignment) inevitably occur during solution-based assembly, severely compromising the electrical conductivity and mechanical strength. Here, we demonstrate that reconstructing the interfacial hydration environment using cellulose nanofibers (CNFs) provides an effective route to regulate the assembly dynamics of graphene oxide nanosheets. The hydroxyl-rich surfaces of CNFs establish robust interfacial hydration layers through dynamic hydrogen-bonding interactions with both graphene nanosheets and water molecules, which regulate nanosheet assembly while suppressing capillary-induced structural disorder during solvent removal. Consequently, the reduced graphene composite sheets exhibit highly ordered in-plane alignment and interlayer stacking coherence. The resultant sheets achieve an ultrahigh electrical conductivity of 1454.9 S cm −1 , a favorable tensile strength of 738.3 MPa, and excellent mechanical durability, retaining over 91.6% of their initial capacitance after 10,000 bending cycles. This work reveals the pivotal role of interfacial hydration in governing the assembly dynamics of graphene nanosheets and establishes a general framework for constructing highly ordered graphene architectures toward high-performance electronic devices. Download: Download high-res image (193KB) Download: Download full-size image
✓ 已验证
产品关联
DOI
高影响因子
ADVANCED FUNCTIONAL MATERIALS
·
2026
·
IF 19.9
Xiangyi Zhang,Zihan Xing,Tong Wang,Limin Wu
Passive radiative cooling provides a sustainable, zero-energy cooling pathway, yet it faces a fundamental challenge in humid or cloudy conditions due to the blockage of the atmospheric transparency window and increased downward atmospheric radiation. Herein, we present a hierarchical Janus bilayer metafabric (TS/PLU) that synergistically combines radiative and evaporative cooling for thermal management with humidity resilience. Integrating a hydrophobic TPU/h-SiO 2 reflection layer with a hygroscopic PAN/LiCl@UiO-66 regulation layer achieves superior solar reflectance (>96%), high atmospheric-window emissivity (96.6%), and moisture capture and evaporation. Crucially, a “harvest-storage-release” mechanism is enabled by UiO-66-confined LiCl, mitigating deliquescence and salt leakage while facilitating heat dissipation even when radiative power is attenuated by high humidity. Asymmetric wettability ensures unidirectional water transport, preserving the radiative function of the hydrophobic top layer. Outdoor tests demonstrate a maximum sub-ambient temperature reduction of 13.4°C under sunny conditions, with a net radiative cooling power of 132.87 W m −2 . The LiCl@UiO-66 incorporation contributes an additional 5.1°C cooling enhancement relative to non-hygroscopic controls. Combined with mechanical robustness (≈370% elongation) and washing durability, this multimodal strategy offers a material-level proof of concept for thermal management featuring humidity resilience and shows potential relevance to personal cooling, outdoor thermal protection, and building-envelope cooling.
✓ 已验证
产品关联
DOI
高影响因子
CARBOHYDRATE POLYMERS
·
2026
·
IF 13.2
Wei Liu,Xuan Wang,Rui Xu,Tairan Pang,Siyu Chen,Yuhan Liu,Ting Xu,Bo Pang,Haishun Du,Chuanling Si
The development of green and sustainable strategies to produce cellulose nanofibrils (CNFs) with tailored surface chemistry for interfacial stabilization and advanced functional composites is of significant importance. In this study, acetylated CNFs were fabricated through FeCl₃-catalyzed acetic acid (AA) pretreatment followed by high-pressure homogenization, enabling simultaneous hydrolysis and surface acetylation. The optimized CNFs exhibited a narrow diameter distribution, enhanced thermal stability, and increased acetyl group content, resulting in improved amphiphilicity and interfacial activity. The modified CNFs effectively stabilized oil-in-water Pickering emulsions over a wide range of oil contents with excellent long-term stability. Incorporation of the CNFs-stabilized emulsions into a waterborne polyurethane (WPU) matrix yielded flexible composite films with high transparency (>88%) and tunable haze (up to ∼82%). The close refractive index matching among CNFs, WPU, and oil droplets, together with controlled microscale scattering, enabled the decoupling of transparency and haze. This work establishes a sustainable catalytic route for producing surface-functionalized CNFs for interfacial engineering and light-management applications.
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）