Matter
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2024
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IF 17.3
Youbing Li,Shuairu Zhu,Jia-Bo Le,Jun Lu,Xue Wang,Lu Chen,Haoming Ding,Ke Chen,Mian Li,Shiyu Du,Hui Wang,Runnan Zhang,Per O.Å. Persson,Lars Hultman,Per Eklund,Yongbo Kuang,Zhifang Chai,Qing Huang
M n+1 AX n (MAX) phases have attracted significant attention due to their structural diversity and potential applications. Designing MAX phases with single-atom-thick A layers featuring 4d/5d-orbital electronic elements is interesting work. Here, we present a comprehensive report on noble metal-based M 2 (A 1- x A′ x )C (M = V, Ti, Nb; A = Al, Sn, In, Ga, Ge; A′ = Ru, Rh, Pd, Ir, Pt, Au and combinations thereof; 0 < x ≤ 0.4) phases featuring A sublayers of 4d/5d-orbital electronic elements through an A-site alloying strategy. The chemical composition of MAX phases can be adjusted by selecting different M- and A-site elements, with morphology tailored by distinct C sources. Furthermore, the V 2 (Sn 0.8 Pt 0.2 )C (15.7 wt % Pt) catalyst showed better performance for hydrogen evolution reaction compared to the commercial Pt/C (20 wt % Pt) electrode. This study highlights the prospects of A-site alloying for the design of novel MAX phases with unique properties and promising applications in electrocatalysis and beyond.
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ELECTROCHIMICA ACTA
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2017
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IF 4.798
Rong Wang,Shengxia Zhang,Yun Su,Junxia Liu,Ye Ying,Feng Wang,Xiaowei Cao
A semi-solid state electrochromic device with deep eutectic solvent gel as the electrolyte, Ethyl-viologen as the electrochromic compound, and K 4 Fe(CN) 6 as the electron donor was reported. Four kinds of silica were simply mixed with ethaline for preparing the gel electrolyte, and the hydrophilic ones were found to be capable of being used as the gelling agent . To enhance the electron transfer at the electrode/gel interface and keep the transparency of the electrode, tiny amount of Au was electrochemically deposited on the FTO electrode. The as-prepared electrochromic device shows a coloration time of ca. 60 s at −0.7 V with the coloration efficiency of 91 cm 2 /C, and a bleaching time of ca. 150 s at 0 V with the efficiency of 194 cm 2 /C. The reversible response of the electrochromic device up to 820 cycles with Δ T max > 60% was also demonstrated.
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JOURNAL OF ALLOYS AND COMPOUNDS
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2025
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IF 6.3
Ling Cen,Yu He,Qingyou Liu,Linli Xu,Yanxiang Yuan
Arsenopyrite, a significant natural Au-host mineral, is often intergrown with sulfide minerals, complicating its isolation. Synthesizing high-purity, dense Au-bearing arsenopyrite is essential for studying its properties. This study employed hot-press sintering (with optimal conditions identified at 450°C and 1.0 GPa) using purified arsenopyrite and Au powders to fabricate conductive, dense Au-bearing arsenopyrite. The sintered product exhibited high purity and increased density (6.259 ± 0.021 g/cm 3 vs. the original 5.923 ± 0.037 g/cm3). Electrochemical testing (via open-circuit potential and cyclic voltammetry) demonstrated favorable performance of the synthesized material. Density functional theory (DFT) calculations confirmed phase stability under 0–10 GPa, revealing that Au preferentially substitutes for Fe in arsenopyrite, introducing gap states that convert it from a semiconductor (indirect bandgap: 0.7075 eV) to a conductor. Bader charge analysis indicated Au carries a negative charge (-0.056 e), while As exhibits positive charges. Fe was identified as the most reactive site. These results provide a high-purity material platform for studying Au-bearing arsenopyrite and a theoretical basis for elucidating its properties.
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Journal of Environmental Chemical Engineering
·
2025
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IF 7.2
Wenhui Zhou,Boxu Dong,Shan Zhu,Fengxiang Ma,Ziqi Si,Likui Feng,Liang Zhang,Yue Zhao,Jiantao Zai,Xuefeng Qian
A Mo 2 C-bridged MoO x /N-doped carbon heterostructure (MoO x -Mo 2 C-N@C) synthesized via one-step calcination demonstrates exceptional photocatalytic activity for sulfur hexafluoride (SF 6 ) degradation, achieving a remarkable capacity of 2.12 mmol/g under UV irradiation, tenfold higher than commercial MoO 2 . The enhanced performance originates from synergistic interfacial electronic modulation: Mo 2 C channels create electron-deficient Mo sites that facilitate SF 6 adsorption and S–F bond cleavage, while N-doped carbon matrices promote charge separation and protect active centers against fluorine poisoning. This work presents an effective metal–carbon hybrid strategy for activating super-stable molecules through rational interface engineering.
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ACS Nano
·
2025
·
IF 16
Jingkai Wang,Jiangjie Chen,Jinyang Chen,Kaishun Xia,Pengcheng Yuan,Xiaopeng Zhou,Ronghao Wang,Chao Yu,Yi Li,Kesi Shi,Yuang Zhang,Haibin Xu,Tengfei Zhao,Hao Li,Qixin Chen,Shiqing Feng,Chengzhen Liang
The central nervous system (CNS) barrier obstructs therapeutic component entrance and hinders the therapy efficiency of CNS diseases. An ideal delivery system should penetrate and concentrate in the CNS without safety concerns. Nanovesicles (NVs) are a popular delivery tool, because of their biological homology, inherent homing effects, and capacity to penetrate barriers. However, the delivery efficacy of NVs is insufficient for CNS disease therapy, and the mechanism for barrier penetration remains elusive. Herein, nanovesicles (NVs) were extruded from mesenchymal stem cells and modified by a lesion tissue affinity peptide (CAQK) for spinal cord injury (SCI) therapy. The NVs penetrated endothelial barriers effectively in vitro. Subsequently, the CNS barrier penetration capacity of the CAQK-conjugated NVs (CNVs) was verified in vivo in spinal cord injury (SCI) and the temporary middle cerebral artery occlusion (t-MCAO) mouse models. Furthermore, the endothelial barrier penetration of CNVs depended on the active endocytosis by endothelial cells. After endocytosis, the Rab11+ endosome was identified to mediate a transcellular transcytosis to transport CNVs across the barrier. In the SCI model, CNVs promoted the lesion tissue accumulation, leading to improvement in the neural functional recovery. In summary, we developed a natural NV tool for SCI therapy, employing the inherent CNS barrier penetration capacity and enhanced lesion tissue homing characteristics of NVs. The NVs crossed the CNS barriers via active endocytosis, followed by Rab11+ endosome-mediated transcytosis. The CNV exhibited good delivery efficacy and therapeutic effects in CNS diseases and has the potential for clinical translation.
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PubMed
高影响因子
FOOD CHEMISTRY
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2024
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IF 8.5
Shengxi Zhai,Mengyuan Bai,Fengling Yue,Haifang Wang,Jingcheng Huang,Haowei Dong,Bei Yuan,Zhengtao Li,Pengwei Zhang,Mingxin Zhao,Yemin Guo,Xia Sun,WenPing Zhao
A lateral flow chromatography strip (LFS) is a chromatography-based biosensor with advantages of convenient carrying, simple operation and rapid detection. In this study, a novel rapid detection technique of aptamer-based chromatography strip was developed and used for the first time for the residue detection of tetracycline antibiotics (TCs) in various milk samples. In this method, gold nanoparticles (AuNPs) modified by TCs specific aptamers were used as probes, and cationic polymers as a capture molecule in a test line (T-line). Meanwhile, the analysis of the gray value of the T-line enabled a linear detection range of 1–300 nM and a limit of detection (LOD) of 0.33 nM for quantitative analysis. The biosensor demonstrated specificity, stability, and successfully detected tetracyclines in milk samples with recovery between 93.60 %–106.20 %. This method sets a basis for multi-residue antibiotics detection in diverse samples, showing potential for on-site applications.
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PubMed
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ACS Nano
·
2024
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IF 15.8
Binbin Chu,Zhiming Chen,Xiaofeng Wu,Haoliang Shi,Xiangbowen Jin,Bin Song,Mingyue Cui,Yadan Zhao,Yingying Zhao,Yao He,Houyu Wang,Fenglin Dong
To date, long-term and continuous ultrasonic imaging for guiding the puncture biopsy remains a challenge. In order to address this issue, a multimodality imaging and therapeutic method was developed in the present study to facilitate long-term ultrasonic and fluorescence imaging-guided precision diagnosis and combined therapy of tumors. In this regard, certain types of photoactivated gas-generating nanocontrast agents (PGNAs), capable of exhibiting both ultrasonic and fluorescence imaging ability along with photothermal and sonodynamic function, were designed and fabricated. The advantages of these fabricated PGNAs were then utilized against tumors in vivo, and high therapeutic efficacy was achieved through long-term ultrasonic imaging-guided treatment. In particular, the as-prepared multifunctional PGNAs were applied successfully for the fluorescence-based determination of patient tumor samples collected through puncture biopsy in clinics, and superior performance was observed compared to the clinically used SonoVue contrast agents that are incapable of specifically distinguishing the tumor in ex vivo tissues.
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PubMed
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SENSORS AND ACTUATORS B-CHEMICAL
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2025
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IF 7.7
Yanpei Xu,Silong Li,Shuxian Gao,Fudong Jia,Liang Guo,Jiangrong Hou,Shaowei Ma,Heya Zheng,Chuxiao Sun,Qi Wang
Prostate-specific antigen (PSA) detection is vital for early prostate cancer diagnosis, yet conventional methods suffer from sensitivity and label-dependent limitations. This study presents a surface plasmon resonance (SPR) biosensor enhanced by Ni(OH) 2 /Ti 3 C 2 T x MXene nanocomposites (NTC) for sensitive detection of total PSA (tPSA) in serum. The NTC architecture synergizes carboxyl-functionalized MXene, amplifying localized electric fields and antibody-binding sites, with Ni(OH) 2 nanoflowers that prevent MXene stacking and enhance refractive index (RI) sensitivity. Optimized via finite element modeling (50-nm Au film, 72.4 ° incident angle), the Au-NTC architecture achieved a 39.34% improvement in RI sensitivity (3064.86 nm/RIU) compared to pristine Au. Through the dual signal amplification mechanism of synergistic enhancement by nanomaterials and sandwich method with gold nanoparticles, enabled detection of tPSA in 20% serum across a wide dynamic range (0.2–160 ng/mL), fully covering the clinical risk threshold (4–10 ng/mL). The platform demonstrated an ultralow limit of detection (LOD) of 0.0361 ng/mL (0.5157 pM) and high specificity against interferons. Kinetic analysis revealed strong antigen-antibody affinity (equilibrium dissociation constant K D = 4 . 26 × 1 0 − 10 M), while batch-producible sensor chips and integrated microfluidics underscored practical applicability. This work advances label-free SPR biosensing for precision prostate cancer diagnostics, offering significant potential in point-of-care testing and early intervention strategies.
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