ACS Sustainable Chemistry & Engineering
·
2020
·
IF 7.632
Tiantian Ping,Yu Dong,Shufeng Shen
Nonaqueous amine-based absorbents by replacing water with organic solvents have potential advantages of low energy penalty and reduced amine degradation for CO2 capture. An advanced nonaqueous system of 2-(butylamino)ethanol (BAE) with 2-butoxyethanol (EGBE) was proposed for low-energy consumption CO2 capture. EGBE was selected as a green cosolvent because of its superior properties over the reported organics and water. A comprehensive study on CO2 capture performance has been performed for secondary alkanolamine nonaqueous systems such as 2-(methylamino)ethanol (MAE), 2-(ethylamino)ethanol (EAE), and BAE and their aqueous counterparts. Product species in CO2-loaded solutions were identified by 13C nuclear magnetic resonance and Fourier transform infrared spectroscopy. Regeneration energy consumption was also evaluated using a modified method and compared with that of conventional aqueous monoethanolamine (MEA). Results demonstrated that the aqueous 5.0 M secondary amine absorbents had higher absorption capacity and larger cyclic capacity than their nonaqueous counterparts. The desorption efficiency for both systems was in a descending order: BAE > EAE > MAE. Surprisingly, the cyclic capacity of aqueous and nonaqueous BAE systems was about 180 and 100% higher than that of aqueous MEA, respectively. The underlying reasons were also discussed. CO2 can react with these amines, forming unstable carbamates and protonated amines in the EGBE solvent, whereas it forms bicarbonate species in addition to ionic couples in aqueous solutions. The regeneration heat duty of nonaqueous EGBE-based secondary amine absorbents was about 45–55% lower than that of aqueous MEA (3.82 MJ kg–1 CO2). In addition, the feasibility of low-temperature desorption makes the BAE/EGBE absorbent a compelling solution for energy-saving CO2 capture technology using low-grade industrial waste heat.
研究领域:
化学工程
·
环境科学
✓ 已验证
DOI
高影响因子
ELECTROCHIMICA ACTA
·
2020
·
IF 6.215
Shuai Li,Tianxiang Yang,Wenlian Wang,Jing Lu,Xiaoyang Zhao,Weizhen Fan,Xiaoxi Zuo,Junmin Nan
2-thiophene sulfonamide (2-TS) is demonstrated as a multi-functional additive to functionalize the electrolyte and improve the performances of LiNi 0.8 Mn 0.1 Co 0.1 O 2 (NCM811)/graphite batteries . Compared with the batteries without 2-TS, the performances of batteries with 2-TS containing electrolyte are significantly improved at wide temperature and high cut-off charge voltage of 4.40 V (vs. Li/Li + ）. After 500 cycles at room temperature and in the voltage range of 2.80–4.20 V, the batteries with 1% 2-TS and without 2-TS additive lose 8.40% and 23.59% initial discharge capacity, respectively. At an elevated temperature of 45 °C and in the voltage range of 2.80–4.40 V, the cycle performance of the batteries with 1% 2-TS is also enhanced, i.e., 68.68% initial discharge capacity is remained after 115 cycles, while the batteries without 2-TS has already decayed to the lifespan point. It is shown that 2-TS molecules can both consume the H 2 O/HF residues to alleviate the decomposition of LiPF 6 and preferentially react on the electrodes to form uniform and dense low-resistance films. These results demonstrate this electrolyte can effectively improve the battery performances and has promising prospects applying in high-voltage and high-nickel NCM-based batteries.
研究领域:
材料科学
·
电化学
·
能源存储
✓ 已验证
产品关联
DOI
高影响因子
CHINESE JOURNAL OF CHEMISTRY
·
2017
·Vol. 35
·期 7
·1086-1090
·
IF 1.852
Youjun Guan,Qi Shi,Jinxiang Dong
1D compound [Zn(Im)(HIm) 2 (OAc)] was used as a single precursor of metal and imidazole to prepare several 3-dimensional (3D) Zn(Im) 2 frameworks by solution-mediated transformation. Specifically, three known topologies, zni, coi and crb (BCT) were obtained using a solution-mediated transformation with CH 3 OH, DMF and DMA as solvent, respectively. Structural studies by 13 C MAS NMR spectroscopy and TG imply that in the transformation process from 1D compound to coi-[Zn(Im) 2 ]•(DMF) x and crb-[Zn(Im) 2 ]•(DMA) x (ZIF-1), DMF and DMA solvent molecules acted as structure-directing agent and, therefore, were occluded inside the framework, respectively. In contrast, in the formation of zni-[Zn(Im) 2 ], no solvent molecules were present in the frameworks; therefore the transformation from 1D compound to zni was induced by temperature. Thus, solution-mediated transformation of a single precursor (1D compound) approach was established for the synthesis of ZIFs.
研究领域:
材料化学
·
配位化学
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF CHEMICAL THERMODYNAMICS
·
2022
·
IF 3.269
Pan Zhang,Yanxi Ji,Wenya Li,Lihua Xu,Lemeng Wang,Dong Fu
The viscosities of N -(2-aminoethyl)ethanolamine (AEEA), 1,4-butanediamine (BDA) and N-methyl- 1,3-propane- diamine (MAPA) activated 2- diethylaminoethanol (DEAE) aqueous solutions were measured at temperatures ( T ) from 303.2 K to 323.2 K, respectively. The DEAE mass fractions ( w DEAE ) and the other three amines ( w AEEA / w BDA / w MAPA ) are 0.300 to 0.500 and 0.050 to 0.150 respectively. The Weiland equation was used to calculate the viscosity of these three solutions, and the calculation results were satisfied with data of the experimental results. With the aid of experimentally determined viscosity data, the activation energy ( E a) of these three solutions was predicted through the Arrhenius formula. With the help of the viscosity data and the diffusion coefficient model of CO 2 in water, the CO 2 diffusion coefficient ( D CO2 ) in these three solutions was calculated. The quantitative relationship between the calculated values (viscosity, activation energy and diffusion coefficient) and the operation conditions (solution mass fraction and temperature) was analyzed. Our results show that the DEAE-BDA absorbent has better application potential due to its lower viscosity, higher CO 2 diffusion coefficient and lower activation energy.
研究领域:
化学工程
·
环境科学
✓ 已验证
DOI
高影响因子
Chemistry-An Asian Journal
·
2024
·
IF 3.5
Xinxin Dai,Zhen Tang,Xinyuan Yan,Shiyi Tao,Shanshan Wang,Yi Liu,Jiafeng Cao,Xiaolong Deng,Xin Bo
The exploring and developing non-precious transition metal-based catalysts for practical water electrolysis with the low cost, high efficiency and easy macroscopic preparation was still a challenge. Herein, Ni 3 S 2 /Ni(OH) 2 heterojunction with different sulfuration time was proposed and hydrothermally synthesized using a simple two-step approach, which served as a bifunctional electrocatalyst for water splitting in alkaline solution at industrial temperature. Among these catalysts, Ni 3 S 2 /Ni(OH) 2 -5h displayed the smallest overpotentials (237 mV@100 mA cm −2 and 360 mV@100 mA cm −2 ) for OER and HER at room temperature, along with low Tafel slopes of 62.0 mV dec −1 and 80.8 mV dec −1 respectively. Furthermore, working at high temperature Ni 3 S 2 /Ni(OH) 2 -5h exhibited even lower overpotential of 82 mV@100 mA cm −2 at 70 °C for OER and 325 mV@100 mA cm −2 at 60 °C for HER. The excellent performance was ascribed to the heterojunction accelerating the charge transfer, hierarchical interconnected structure promoting the mass transfer and the synergistic effect between the components of Ni 3 S 2 and Ni(OH) 2 . This work could provide a promising route for promoting the electrocatalytic performance of Ni-based catalyst with a simple sulfuration method for industrial water splitting, which could expand to other non-noble metal-based materials for enhancing the electrocatalytic activities.
研究领域:
材料科学
·
电化学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Systems Microbiology and Biomanufacturing
·
2025
·
IF 2.9
Li Zihan,Zhao Guihong,Zhang Dezhi,Tang Yaqun,Liu Geer,Wang Xiaoyuan
2′-Fucosyllactose is the most abundant human milk oligosaccharides and one of the three essential nutrients for infant growth. Corynebacterium glutamicum is one of the most common industrial fermentation bacteria but cannot synthesize 2′-fucosyllactose. In this study, C. glutamicum ATCC13032 was engineered for 2′-fucosyllactose production from fucose and lactose. The gene futC from Helicobacter pylori encoding α-1,2-fucosyltransferase was codon optimized and mutated at four amino acids (F40S/Q150H/C151R/Q239S). The modified gene futC and the gene fkp from Bacteroides thetaiotaomicron encoding fucokinase/GDP-fucose pyrophosphorylase were overexpressed in plasmid pEC and transformed into C. glutamicum , resulting in CW002. CW002 did not synthesize 2′-fucosyllactose possibly because the substrates fucose and/or lactose did not pass through the cell membrane. Therefore, the gene lacY encoding lactose permease and the gene fucP encoding fucose permease from Escherichia coli were overexpressed in plasmid pXTuf and transformed into CW002, resulting in CW006. CW006 did synthesize 2′-fucosyllactose as expected. It is interesting that the production of 2′-fucosyllactose was decreased or stopped when the expression combination of these four genes was changed, suggesting that the expression levels of the four genes in CW006 might have to well balanced. C. glutamicum CW006 produced 2.07 g/L 2′-fucosyllactose in a 2.4 L bioreactor.
研究领域:
微生物学
·
生物工程
·
分子生物学
·
食品科学
✓ 已验证
DOI
高影响因子
MOLECULES
·
2024
·Vol. 29
·期 8
·1721
·
IF 4.2
Shoudong Wang,Lei Zhou,Hongyun Qin,Zixu Dong,Haoyuan Li,Bo Liu,Zhilu Wang,Lina Zhang,Qiang Fu,Xia Chen
Hydrofluorocarbons (HFCs) have important applications in different industries; however, they are environmentally unfriendly due to their high global warming potential (GWP). Hence, reclamation of used hydrofluorocarbons via energy-efficient adsorption-based separation will greatly contribute to reducing their impact on the environment. In particular, the separation of azeotropic refrigerants remains challenging, such as typical mixtures of CH2F2(HFC-23) and CHF3(HFC-32), due to a lack of adsorptive mechanisms. Metal–organic frameworks (MOFs) can provide a promising solution for the separation of CHF3–CH2F2mixtures. In this study, the adsorption mechanism of CHF3–CH2F2mixtures in TIFSIX-2-Cu-i was revealed at the microscopic level by combining static pure-component adsorption experiments, molecular simulations, and density-functional theory (DFT) calculations. The adsorption separation selectivity of CH2F2/CHF3in TIFSIX-2-Cu-i is 3.17 at 3 bar under 308 K. The existence of similar TiF62−binding sites for CH2F2or CHF3was revealed in TIFSIX-2-Cu-i. Interactions between the fluorine atom of the framework and the hydrogen atom of the guest molecule were found to be responsible for determining the high adsorption separation selectivity of CH2F2/CHF3. This exploration is important for the design of highly selective adsorbents for the separation of azeotropic refrigerants.
研究领域:
材料科学
·
环境科学
·
化学工程
✓ 已验证
产品关联
DOI
PubMed
高影响因子
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
·
2020
·
IF 2.985
Ruixue Wang,Lianyun Lin,Yiqiang Zheng,Peng Cao,Zhiguang Yuchi,Hui-Yuan Wu
Cytosolic carboxypeptidases (CCPs) comprise a unique subfamily of M14 carboxypeptidases and are erasers of the reversible protein posttranslational modification– polyglutamylation . Potent inhibitors for CCPs may serve as leading compounds targeting imbalanced polyglutamylation. However, no efficient CCP inhibitor has yet been reported. Here, we showed that 2-phosphonomethylpentanedioic acid (2-PMPA), a potent inhibitor of the distant M28 family member glutamate carboxypeptidase II (GCPII), rather than the typical M14 inhibitor 2-benzylsuccinic acid, could efficiently inhibit CCP activities. 2-PMPA inhibited the recombinant Nna1 (a.k.a. CCP1) for hydrolyzing a synthetic peptide in a mixed manner, with Ki and Ki’ being 0.11 μM and 0.24 μM respectively. It inhibited Nna1 for deglutamylating tubulin, the best-known polyglutamylated protein, with an IC 50 of 0.21 mM. Homology modeling predicted that the R-form of 2-PMPA is more favorable to bind Nna1, unlike that GCPII prefers to S-form. This work for the first time identified a potent inhibitor for CCP family.
研究领域:
生物化学
·
药物化学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
ELECTROCHIMICA ACTA
·
2017
·
IF 4.798
Zhonghua Xue,Xiaoxia Fu,Honghong Rao,Xibin Zhou,Xiuhui Liu,Xiaoquan Lu
As efficient electron transfer mediator, various nanomaterials with smart performance have been explored in non-enzymatic sensor fabrication. We herein present an electron transfer mediator actuated electrochemical non-enzymatic sensor to assay nitrite, enabled by electrochemical reduced graphene oxide (ERGO) and 1-(2-pyridylazo)-2-naphthol (PAN). The composites of PAN-ERGO coating on electrode surface were successfully fabricated through a facile and green cyclic voltammetry technique. With the aid of ERGO nanosheets on the electrode surface, the electron transfer mediator of PAN nanostructures was easily immobilized and hybridized with ERGO, resulting in a remarkably synergistic effect between ERGO sensing substrate and the electrodeposited PAN coating for target electron transfer. The results demonstrated that the electrocatalytic current increased linearly with the nitrite concentration in the range of 7.49–1752.6 μM and 1752.6–3500 μM, with a good detection limit of 0.67 μM and 1.44 μM (signal-to-noise ratio, S/N = 3), respectively. The present work provide some new insights for the smart design of high efficiency electrocatalytic materials that based on the composites of electrochemical reduced graphene oxide and other substances.
研究领域:
分析化学
·
材料科学
·
电化学传感器
✓ 已验证
DOI
高影响因子
Frontiers in Pharmacology
·
2023
·
IF 5.6
Niu Ting,Wei Zhiying,Fu Jiao,Chen Shu,Wang Ru,Wang Yuya,Zheng Ruihe
Introduction: Venlafaxine is one of the most commonly used anti-depressant and antineoplastic drug. Previous studies have predicted venlafaxine as an anti-cancer compound, but the therapeutic effects of venlafaxine in melanoma have not yet been demonstrated. Nur77 is an orphan nuclear receptor that highly expressed in melanoma cells and can interact with Bcl-2 to convert Bcl-2 from an antiapoptotic to a pro-apoptotic protein.Method: We examined the effects of venlafaxine in MV3 cells in vitro and MV3 xenograft tumor in nude mice. Western-blot, PCR, TUNEL assay and immunofluorescence were used to reveal the growth of melanoma cells.Results: Here, our data revealed that venlafaxine could reduce the growth, and induce apoptosis of melanoma cells through a Nur77-dependent way. Our results also showed that treatment with venlafaxine (20 mg/kg, i.p.) potently inhibited the growth of melanoma cells in nude mice. Mechanistically, venlafaxine activated JNK1/2 signaling, induced Nur77 expressions and mitochondrial localization, thereby promoting apoptosis of melanoma cells. Knockdown of Nur77 and JNK1/2, or inhibition of JNK1/2 signaling with its inhibitor SP600125 attenuated the anti-cancer effects of venlafaxine.Conclusion: In summary, our results suggested venlafaxine as a potential therapy for melanoma.
研究领域:
肿瘤学
·
药理学
·
细胞生物学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
FOOD CHEMISTRY
·
2025
·
IF 9.8
Feng Wang,Xianhong Bi,Yun Cui,Kewei Lin,Charles Brennan,Soottawat Benjakul,Gengsheng Xiao,Lukai Ma
Toxic compounds in fried food products attract increasing attention, but studies regarding the levels of common toxins, such as malondialdehyde (MDA), 4-hydroxy-2-hexenal (4-HHE), and 4-hydroxy-2-nonenal (4-HNE), in fried starch-based food (FSBF) are scarce. Herein, we investigated the formation and distributions of these aldehydes in FSBF, and the frying oil and FSBF retained higher levels of low-molecular-weight aldehydes. The highest aldehyde concentrations were observed in French fries. Simulated frying experiments revealed that the distributions of the toxic aldehydes in FSBF were mainly determined by the amylose content. Molecular dynamics simulations indicated that amylose interacted strongly with 4-HNE, but its interactions with MDA and 4-HHE were weaker. The migration of MDA, 4-HHE, and 4-HNE into FSBFs was primarily attributed to the interactions between the toxic aldehydes and amylose. This study should provide a novel basis for the control and elimination of toxic aldehydes in fried food.
研究领域:
食品安全
·
分子生物学
·
营养学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
CRYSTAL GROWTH & DESIGN
·
2024
·
IF 3.2
Huiqin Ma,Zhuxiang Mao,Wen Liu,Yahao Zhao,Peng Liu,Difu Zhan,Qian Fu,Yizhong Huang,Changcun Han
ZnIn2S4 (ZIS) is an N-type direct bandgap semiconductor material with a visible light response, which exhibits excellent photocatalytic water-splitting performance. To enhance ZIS-based photocatalysts, heterojunction construction and cocatalyst loading methods have been explored extensively. In this research, a Co9S8/ZnIn2S4 (CS/ZIS) heterojunction was successfully synthesized via a solvothermal method, and then Ni(OH)2 nanoparticles were successfully loaded on CS/ZIS by photodeposition, yielding the Ni(OH)2/CS/ZIS photocatalyst. Our findings reveal tight coupling of ZIS nanosheets with the CS surface, establishing an effectively constructed heterojunction structure that enhances interface charge transfer and light absorption. The synergistic effect of CS and Ni(OH)2 significantly boosts the photocatalytic hydrogen production of ZIS composites. The optimum hydrogen production rate of CS/ZIS is 10.06 mmol·h–1·g–1 and that of Ni(OH)2/CS/ZIS reaches 12.92 mmol·h–1·g–1, a 11.9-fold increase over pure ZIS, with exceptional light stability. Furthermore, we discuss the photocatalytic reaction mechanism based on the experimental and characterization results. This work presents a novel approach to designing highly efficient photocatalysts using ZnIn2S4, aimed at enhancing the conversion of solar energy into chemical energy.
研究领域:
材料科学
·
能源化学
·
纳米技术
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）