SENSORS AND ACTUATORS B-CHEMICAL
·
2019
·
IF 6.393
Hongji Li,Junqing Qin,Mingji Li,Cuiping Li,Sheng Xu,Lirong Qian,Baohe Yang
A boron-doped graphene (BG)/boron-doped diamond (BDD) composite film was obtained by continuously growing BDD and BG by chemical vapor deposition. In this process, the sp 3 C C bonds in the diamond phase structure are directly converted into sp 2 C C bonds in graphene to combine the two carbon materials, while BG nanosheets are vertically grown on the exposed planes of BDD crystals. These process features impart the vertical BG (VBG)/BDD film a large specific surface area and high electrocatalytic activity, resulting in an electroactive surface area of 2.35 cm 2 . Electrodeposition can be used to load a large number of Au nanoparticles (NPs) on the VBG/BDD electrode. The Au-VBG/BDD electrode was used to construct an immunosensor capable of simultaneously quantifying carcinoembryonic antigen (CEA) and carcinoma antigen 125 (CA 125) at concentrations of 0.5–100 pg mL –1 and 0.5–100 mU mL –1 , respectively, with corresponding detection limits of 0.15 pg mL –1 and 0.09 mU mL –1 . This method is suitable for the practical detection of CEA, CA125, and other tumor markers in human body fluids, allowing early cancer diagnostics and timely treatment.
研究领域:
材料科学
·
分析化学
·
生物医学工程
·
癌症诊断
✓ 已验证
DOI
高影响因子
JOURNAL OF MOLECULAR STRUCTURE
·
2025
·
IF 4.7
Zhijiang Rong,Wei Guo,Haotian Liang,Huan Lv,Hua Guo,Yi Zhang,Bo Zhang,Chunyan Hao,Xianjun Liu,Hongyan Sun,Yifan Gao
Biological metal ions play crucial roles in various life processes and exhibit diverse biological functions. Specifically, Ca(II), Mg(II), Cu(II), and Mn (II) ions are intricately involved in insulin function. To further clarify the biological functions of biological metal ions on insulin, the interaction mechanism of insulin affected by Ca(II), Mg(II), Cu(II), and Mn (II) ions were comparably investigated via spectroscopic, circular dichroism(CD), and electrochemical approaches. Electrochemical studies demonstrate that Mn(II) forms an M 2 L-type complex with insulin, exhibiting a binding constant of β Mn = 9.3 × 10 9 , while Cu(II) and insulin form an M 4 L-type complex with a significantly higher binding constant of β Cu =9.18 × 10 12 . Electrochemical investigation of the interaction between Ca(II) and Mg(II) with insulin adsorbed onto a glass carbon electrode surface revealed that the presence of Ca(II) and Mg(II) induced conformational changes in insulin, resulting in reduced adsorption capacity. Additionally, it was observed that the presence of Ca(II) and Mg(II) enhanced the redox signal of probe ions. The binding constants values were calculated to be 1.108 × 10 3 L•mol –1 for the insulin-Ca(II) system and 2.28 ×10 2 L• mol –1 for the insulin-Mg(II) system. Spectroscopic studies showed that the binding of Cu(II) ions to insulin molecules may be controlled by chelation mechanism, and the interaction between Cu(II) ions and insulin molecules may occur in the aromatic region. Mn(II) ion binding is mainly controlled by ionic interactions, and its binding site is far away from the aromatic region.The combination of Ca(II) and Mg(II) with insulin induced a small enhancement in the Ultraviolet-visible (UV) absorption peak, with Ca(II) exhibiting a more pronounced effect compared to Mg(II). The results of spectral, CD and electrochemical studies are consistent.
研究领域:
生物化学
·
电化学
·
分子生物学
✓ 已验证
产品关联
DOI
高影响因子
Journal of the Taiwan Institute of Chemical Engineers
·
2024
·
IF 5.5
Yueyue He,Huaigang Cheng,Zihe Pan,Xiangping Zhang
Heterogeneous catalysts can avoid the problem of difficult separation and recovery of homogeneous catalysts in transesterification reactions, but there is a lack of basis for process optimization because the quantitative influence mechanism of supports is not clear. In this work, we firstly attempt to make a comprehensive comparation on the effect of potassium fluoride (KF) catalysts on various supports (carbonates and oxides of cerium, magnesium and calcium) on the transesterification reaction, especially on the kinetics. According to the results, oxide-supported catalysts are significantly more active than carbonate-supported catalysts because they have more active sites. When oxides were used as supports, KF/MgO exhibited good activity because of its stronger basicity and higher number of active sites on the surface. Under the same process conditions, the stability time of KF/CeO 2 , KF/CaO and KF/MgO catalysed transesterification reaction was 240 min, 90 min and 30 min, respectively. KF/MgO achieved a conversion of 68.0 %. The activation energies of the KF/CeO 2 , KF/CaO and KF/MgO catalysed transesterification reaction were 22.22 kJ/mol, 15.93 kJ/mol and 15.80 kJ/mol, respectively. The surface alkalinity of KF/MgO increased the frequency of molecular collisions of the reactants and exhibited a faster reaction rate.
研究领域:
催化化学
·
材料科学
·
反应工程学
✓ 已验证
产品关联
DOI
高影响因子
FUEL
·
2024
·
IF 6.7
Mengjie Zhang,Xiangpu Jiao,Dezhang Ren,Chenxin Huang,Yang Li,Duofu Chen,Zhibao Huo
The rapid development of the biodiesel industry is of significant importance for achieving carbon emission reduction in the transportation sector. However, the presence of trace amounts of water in the feedstock during biodiesel synthesis may lead to severe saponification reactions, thereby reducing the yield of fatty acid methyl esters. In this study, based on our exploration of the characteristic of porous carbon to absorb moisture from the environment, we synthesized a CaO catalyst with porous carbon coating via discarded shrimp shell biomass. Because the carbonization temperature of organic matter in shrimp shells is lower than the decomposition temperature of CaCO 3 , the CO 2 generated during pyrolysis can erode the pyrolytic carbon and form porous structure. The mesoporous carbon shell facilitates the diffusion of oil and methanol molecules while adsorbing moisture in the alcohol phase. This structure effectively minimizes the interaction between CaO and water, thereby suppressing saponification reactions and ensuring the smooth progression of the desired transesterification reaction. Through a series of physicochemical characterizations, the structure and water absorption performance of the catalyst were confirmed. The as-prepared CaO@PC-900 catalyst demonstrated the ability to maintain a biodiesel yield of over 85% in a reaction system with a water content of 3%, significantly surpassing the performance of commercial CaO and previously reported Ca-based solid bases. This work provides a new approach to the design of anti-saponification transesterification catalysts, while also offering a novel pathway for the synthesis of porous carbon from discarded crustacean biomass.
研究领域:
能源科学
·
催化材料
·
环境科学
✓ 已验证
产品关联
DOI
高影响因子
CERAMICS INTERNATIONAL
·
2024
·
IF 5.1
Lisha Zhang,Yudong Ji,Weidong Li,Bing Zhang,Qiang Ma,Bowen Qin,Yilei Zhang,Dan Yue,Zhenling Wang
Lanthanide ions-doped fluoride nanocrystals have excellent application prospect. However, low photoluminescence quantum yield (PLQY) is usually along with lanthanide ions-doped fluoride nanocrystals owing to their low molar absorptivity and narrow absorption band . In order to increase the absorption cross section of Ln 3+ in fluoride nanocrystals, a facile synthesis strategy to enhance luminescence of AF 2 : Ln 3+ (A = Ca, Sr; Ln = Eu, Tb) by the use of carbon dots (CDs) has been developed in this work. A series of characterizations including TEM , XRD , FTIR and XPS demonstrated that the CDs have been successfully combined with the surface of AF 2 : Ln 3+ nanocrystals. The combination of CDs has little influence on the microstructure and phase structure of AF 2 : Ln 3+ , and CDs@AF 2 : Ln 3+ nanocrystals have uniform and regular shape with cubic phase. CDs are used as a broadband sensitizer and lead to the broadband excitation of Ln 3+ , resulting in the enhancement around 10-fold of Ln 3+ luminescence emission in AF 2 : Ln 3+ nanocrystals after CDs combination. The corresponding PLQY increases almost three times, and the luminescence enhancement mechanism by combining CDs is proposed. In addition, the CDs@AF 2 : Ln 3+ nanocrystals are used to prepare CDs@AF 2 : Ln 3+ /PVA films, which exhibits excellent luminescence properties under the excitation of UV light . This work provides a superior method for enhancing the luminescence properties of lanthanide ions-doped nanocomposites and demonstrates practical potential as promising candidates for light-converting thin films .
研究领域:
材料科学
·
光学
✓ 已验证
产品关联
DOI
高影响因子
MATERIALS SCIENCE FORUM
·
2015
·
IF 0
Xiao Peng Xu,Si Chen,Yan Qin Shi,Bo Zhen Wu,Meng Ma,Xu Wang
The effect of orotic acid (OA) and its mixtures with calcium stearate (CaSt2) and zinc stearate (ZnSt2) in various ratios on the thermal stability of PVC has been investigated by Congo red and discoloration tests. The results shows that OA acts as a long-term thermal stabilizer for PVC like CaSt2, and the combination of OA and ZnSt2 exhibited a synergistic stabilization effect at a certain ratio. This is due to the ability of OA to absorb HCl released during the degradation of PVC to diminish its catalytic effects, and react with ZnCl2 to stop its catalytic effect for PVC. CaSt2-ZnSt2/OA stabilizers exhibit good synergistic effects with both acceptable initial color and long-term stability for PVC
研究领域:
材料科学
·
化学工程
✓ 已验证
DOI
Frontiers in Chemistry
·
2017
·
IF 3.994
Yu Xiaopeng,Mi Xueyang,He Zhihui,Meng Minjia,Li Hongji,Yan Yongsheng
Highly selective cellulose acetate (CA)/poly (vinyl alcohol) (PVA)/titanium dioxide (TiO2) imprinted membranes were synthesized by phase inversion and dip coating technique. The CA blend imprinted membrane was synthesized by phase inversion technique with CA as membrane matrix, polyethyleneimine (PEI) as the functional polymer, and the salicylic acid (SA) as the template molecule. The CA/PVA/TiO2 imprinted membranes were synthesized by dip coating of CA blend imprinted membrane in PVA and different concentration (0.05, 0.1, 0.2, 0.4 wt %) of TiO2 nanoparticles aqueous solution. The SEM analysis showed that the surface morphology of membrane was strongly influenced by the concentration of TiO2 nanoparticles. Compared with CA/PVA-TiO2(0.05, 0.1, 0.2%)-MIM, the CA/PVA-TiO2(0.4%)-MIM possessed higher membrane flux, kinetic equilibrium adsorption amount, binding capacity and better selectivity for SA. It was found that the pseudo-second-order kinetic model was studied to describe the kinetic of CA/PVA-TiO2(0.2%)-MIM judging by multiple regression analysis. Adsorption isotherm analysis indicated that the maximum adsorption capacity for SA were 24.43 mg g−1. Moreover, the selectivity coefficients of CA/PVA-TiO2 (0.2%)-MIM for SA relative to p-hydroxybenzoic acid (p-HB) and methyl salicylate (MS) were 3.87 and 3.55, respectively.
研究领域:
环境科学
·
材料科学
·
化学工程
✓ 已验证
DOI
高影响因子
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
·
2020
·Vol. 27
·期 14
·16745-16753
·
IF 3.056
Yu Cheng,Zhang Yi,Fang Yu,Tan Yujie,Dai Ke,Liu Shilin,Huang Qiaoyun
Shewanella oneidensis MR-1 (MR-1)-impregnated alginate capsules with 3D porous structure were prepared through cation crossing-linking and was used for the Cr(VI) reduction and removal. After being encapsulated by alginate, the endurance of the MR-1 was largely enhanced under conditions of high Cr(VI) concentrations (up to 4 mM) and low pH (pH 5). The Cr(VI) reduction over the MR-1-impregnated alginate capsules could be fitted by pseudo first-order kinetic model. With the Cr(VI) initial concentration increasing from 1 to 4 mM, the first-order rate constant for the encapsulated MR-1 ( k capsules ) and free cells ( k cells ) fell by 26.3% and 82.4%, respectively. At pH 5, the k capsules value was 0.19 h − 1 , which was about 3.7 times higher than k cells . Moreover, the encapsulated MR-1 held 90.5% of the Cr(VI) reduction ability after 15 days of resting time, while the free MR-1 held 19.7%. After bioreduction, 73.6% of total chromium was adsorbed on the MR-1 impregnated Ca-alginate capsules. XPS results showed 85% of the adsorbed chromium was Cr(III). The mechanism for chromium removal over the MR-1-impregnated Ca-alginate capsules was proposed with the following steps: (1) Cr(VI) was bioreduced via the encapsulated MR-1; (2) the reduced soluble Cr(III) was adsorbed by alginate selectively. In the study, the Ca-alginate shell of the cabbage-like MR-1 impregnated capsules could be a shelter for encapsulated MR-1 to endure unfavorable conditions (e.g., low pH and high concentration of Cr(VI)) and immobilize the soluble chromium. Considering the obtained capsules derived from biomolecules were environment-friendly, the MR-1-impregnated Ca-alginate capsules were potential for the application in the remediation of environmental pollution.
Graphical abstract
研究领域:
环境科学
·
微生物学
✓ 已验证
DOI
高影响因子
Arabian Journal of Chemistry
·
2022
·
IF 6.212
Jingbo Wang,Yaxin Kang,Huatai Duan,Yi Zhou,Hao Li,Shanguo Chen,Fenghua Tian,Lianqing Li,Marios Drosos,Changxun Dong,Stephen Joseph,Genxing Pan
Co-pyrolysis of straw and Ca(OH) 2 is a feasible modification method to improve the adsorption capacity of biochar for Cd. However, few studies have quantitatively analyzed the contribution of different adsorption mechanisms of alkali-modified biochar. In this study, the alkali-modified (Ca) biochar were prepared by co-pyrolyzing lime (Ca(OH) 2 ) and soybean straw (SBB) or rape straw (RSB) at 450 °C. The adsorption mechanism was investigated by a series of experiments and was provided by quantitative analysis. The maximum adsorption capacities of Cd 2+ by Ca-SBB and Ca-RSB were calculated to be 78.49 mg g −1 and 49.96 mg g −1 , which were 1.56 and 1.48 times higher than SBB (50.40 mg g −1 ) and RSB (33.79 mg g −1 ), respectively. Compared with the original biochar (SBB, RSB), alkali-modified biochar (Ca-SBB and Ca-RSB) were found to have faster adsorption kinetics and lower desorption efficiencies. The mechanism study indicated that Ca(OH) 2 modification effectively enhanced the contribution of ion exchange and decreased the contribution of functional groups complexation. After Ca(OH) 2 modification, precipitation and ion exchange mechanisms dominated Cd 2 + absorption on Ca-SBB, accounting for 49.85% and 34.94% of the total adsorption, respectively. Similarily ion exchange and precipitation were the main adsorption mechanism on Ca-RSB, accounting however for 61.91% and 18.47% of total adsorption, respectively. These results suggested that alkali-modified biochar has great potential to adsorp cadmium in wastewater.
研究领域:
环境科学
·
土壤修复
✓ 已验证
DOI
高影响因子
Frontiers in Materials
·
2022
·
IF 3.985
Feng Yashan,Chang Lei,Zhu Shijie,Yang Yongxin,Wei Baoli,Lv Meng,Wang Jun,Guan Shaokang
The uncontrollable rapid degradation rate of the Mg alloy substrate limited its clinical application, and implant-associated infections have been reported to be the main reason for the secondary surgery of orthopedic implantation. The aim of this study was to produce a multifunctional coating on magnesium-based alloys that have improved corrosion resistance, bioactivity, and antibacterial properties through the preparation of polyelectrolytic multilayers (PEMs) consisting of chitosan (CS) and sodium hyaluronate (HA) on silane-modified strontium-substituted hydroxyapatite (hereafter referred to as Bil (SH + CS)/SrHA). The multifunctional coatings were characterized by scanning electron microscopy (SEM), X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FT-IR), and X-ray photoelectron spectroscopy (XPS). The results showed the polyelectrolyte complex SH/CS layer to be uniformly and tightly attached on to the surface of silane-treated SrHA. At the same time, a potentiodynamic polarization test and hydrogen evolution test showed the Bil (SH + CS)/SrHA coatings to exhibit superior corrosion resistance than bulk Mg-based alloys. The results of the cell–surface interactions revealed Bil (SH + CS)/SrHA coatings to be in favor of cell initial adhesion and more beneficial to the proliferation and growth of cells with the processing of co-culture. In addition, antibacterial tests demonstrated the strong bactericidal effect of Bil (SH + CS)/SrHA coatings against both Escherichia coli (E. coli) and Staphylococcus (S. aureus), suggesting that Bil (SH + CS)/SrHA coatings can successfully achieve multifunctionality with enhanced corrosion resistance, biocompatibility, and antibacterial properties.
研究领域:
材料科学
·
生物医学工程
·
组织工程
✓ 已验证
DOI
高影响因子
MATERIALS & DESIGN
·
2020
·
IF 6.289
Xuefeng Zhou,Xi Cheng,Danlei Xing,Qi Ge,Yan Li,Xianghong Luan,Ning Gu,Yunzhu Qian
Bioactive synthetic scaffolds with 3D porous structure are the most attractive materials among various guided bone regeneration membranes. However, its osteogenic potential is still insufficient. This study was aimed to develop a Calcium surface-anchored Collagen I-PLGA/PCL scaffolds (PP/COL I-pDA-Ca) with enhanced osteogenicity. PP/COL I-pDA-Ca was electrospun from a collagen I-blended PLGA/PCL matrix and then modified by the chelation of Ca-ions via mussel-inspired polydopamine coating. PLGA/PCL, PLGA/PCL-polydopamine, PLGA/PCL-pDA chelated by Ca-ions were used as controls. Osteogenic effects of the scaffolds were examined using MC3T3-E1 cell culture. PP/COL I-pDA-Ca maintained 3D porous architecture with interconnected pores formed by randomly-oriented filamentous fibers and MC3T3-E1 cells cultured on it for 12 h or 24 h were more stretched and spread than those on the controls. PP/COL I-pDA-Ca significantly upregulated α10, α11 and β1 integrin expression after 48 h culture. ALP activity, OCN, OSX, BMP2 and RUNX2 expression of MC3T3-E1 cells cultured on PP/COL I-pDA-Ca scaffolds for 7 and 14 days were substantially enhanced when compared to controls ( p < 0.05). The pDA-based Ca chelation, COL I incorporation and 3D bionic structure promoted cell adhesion and osteogenic differentiation of MC3T3-E1 cells. This novel PP/COL I-pDA-Ca scaffolds is an attractive alternative for guided bone regeneration.
研究领域:
生物材料
·
组织工程
·
生物医学工程
·
骨科
✓ 已验证
DOI
高影响因子
BIOCHEMICAL ENGINEERING JOURNAL
·
2025
·
IF 3.8
Rui Zhao,Wenhui Yang,Pengyan Yang,Yunhan Cao,Fenghuan Wang
Carbonic anhydrase (CA) has been suggested as a biocatalyst for carbon dioxide capture since it could effectively catalyze the hydration of carbon dioxide. Metal-organic frameworks (MOFs) have attracted significant attention in the development of immobilized enzyme carriers due to their pore tunability and excellent stability. In this study, UiO-67 materials with varying defect degrees (DUiO-67) were prepared using the organic linker missing method to enhance the catalytic performance. The results indicated that both the defect degree and the pore size of DUiO-67 materials decreased with an increase in acetic acid equivalent. After CA immobilization, all DUiO-67 materials exhibited excellent thermal, pH and recycling stability. CA@DUiO-67–25 showed higher enzyme catalytic activity and conversion ability than the other materials. After 10 cycles, CA@DUiO-67–25 retained 57 % of its initial conversion capacity. The construction of defective MOFs provides a promising new strategy for CA immobilization to achieve the catalytic conversion of CO 2 .
研究领域:
材料科学
·
生物催化
·
环境科学
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）