Analytical Methods
·
2020
·Vol. 12
·期 41
·4956-4966
·
IF 2.596
Wenzhan Li,Min Chen,Jintao Liang,Chunting Lu,Min Zhang,Fangrong Hu,Zhide Zhou,Guiyin Li
Herein, a label-free electrochemical aptasensor for alpha-fetoprotein (AFP) analysis was established. The AFP aptamer (AFP-Apt), as the recognition molecule, was immobilized on the surface of a screen-printed carbon electrode, which was modified by gold–platinum metallic nanoparticles and reduced graphene oxide–chitosan–ferrocene nanohybrids (Au–Pt NPs/RGO–CS–Fc), to build the AFP electrochemical aptasensor. The construction process of the aptasensor was characterized by scanning electron microscopy, X-ray photoelectron spectroscopy, Raman spectroscopy, and electrochemical impedance spectroscopy. With the addition of AFP, the formation of the AFP-aptamer conjugation blocked the electron transfer reaction, reducing the differential pulse voltammetric responses of the current of Fc in the RGO–CS–Fc nanohybrids. By optimizing the experimental parameters, AFP could be detected with the dynamic concentration range of 0.001 to 10.0 μg mL−1 and with a detection limit of 0.3013 ng mL−1. In addition, the approach was manifested to have good selectivity, reproducibility, and stability. The fabricated aptasensor had a good recovery rate of 102.36% to 118.09% in real human serum samples. This work demonstrates that the electrochemical aptasensor is a useful tool for analyzing AFP inexpensively, rapidly, and accurately.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
RSC Advances
·
2020
·Vol. 10
·期 26
·15091-15097
·
IF 3.119
Lei Ge,Meng Zhang,Ran Wang,Na Li,Lexin Zhang,Shufeng Liu,Tifeng Jiao
In this study, natural polymer material chitosan (CS) and graphene oxide (GO) with large specific surface area were used to prepare a new CS/RGO-based composite hydrogel by using glutaraldehyde (GA) as cross-linking agent. In addition, a CS/GA/RGO/Pd composite hydrogel was prepared by loading palladium nanoparticles (Pd NPs). The morphologies and microstructures of the prepared hydrogels were characterized by SEM, TEM, XRD, TG, and BET. The catalytic performance of the CS/GA/RGO/Pd composite hydrogel was analyzed, and the experimental results showed that the CS/GA/RGO/Pd composite hydrogel had good catalytic performance for degradation of p-nitrophenol (4-NP) and o-nitroaniline (2-NA). Therefore, this study has potential application prospect in wastewater treatment and provides new information for composite hydrogel design.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2019
·
IF 8.355
Ying Liang,Mingqian Wang,Zhicheng Zhang,Guohong Ren,Yajun Liu,Shishan Wu,Jian Shen
We have constructed biocompatible antibacterial nanoplatforms on the basis of a hybrid hydrogel via simple electrostatic interaction embedded with thin layer graphene oxide (GO) sheets modified with zinc oxide quantum dots (ZnO QDs). The materials possess favorable antibacterial efficacy, thereby providing excellent killing effect for Escherichia coli (Gram-negative) and Staphylococcus aureus (Gram-positive) compared with materials that have single diagnosis and treatment mode. The excellent performance stems from the combined effects of hyperthermia produced under the near-infrared irradiation of GO sheets, reactive oxygen species, the release of Zn 2+ from ZnO QDs under acidic environment, and the antibacterial activity of hydrogel. The synergy of antibacterial nanoplatforms can be used for wound anti-inflammatory in vivo indicated by the wound healing results. The hybrid hydrogel causes no evident side effects to major organs in mice during wound healing. Therefore, the biocompatible multimodal therapeutic nanoplatforms have great potential for antibacterial activity and wound healing.
✓ 已验证
产品关联
DOI
高影响因子
BIODEGRADATION
·
2018
·Vol. 29
·期 6
·593-603
·
IF 2.41
Shi Zhoukun,Dong Weiliang,Xin Fengxue,Liu Jiawei,Zhou Xinhai,Xu Fanli,Lv Ziyao,Ma Jiangfeng,Zhang Wenming,Fang Yan,Jiang Min
Abstract An acetamiprid-degrading fungus was isolated from contaminated soil and identified as Fusarium sp. strain CS-3 based on physiological, biochemical, and molecular analyses. Strain CS-3 exploited 50 mg/L as the sole carbon source in liquid culture, removing 98% in 96 h. Strain CS-3 retained its acetamiprid degradation abilities over a wide range of pH (5.0–8.0) and temperature (20–42 °C). HPLC–MS analysis showed that N ′-[(6-chloropyridin-3-yl)methyl]- N -methylacetamide, 2-chloro-5-hydroxymethylpyridine, and 6-chloronicotinic acid were identified as the most predominant metabolites, forming the basis for a newly described acetamiprid degradation pathway. Strain CS-3 efficiently degraded 99.6% of 50 mg/kg acetamiprid in soil, indicating potential for soil remediation. Graphical abstract
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Nanoscale
·
2025
·
IF 5.1
Han Li,Shanshan Yu,Handong Jin,Zikun Jin,Wei Qian,Wanshun Yang,Shihe Yang
Direct conversion X-ray detectors based on metal halide perovskites (MHPs), notably CsPbBr₃, promise high performance but suffer from detrimental dark currents and ion migration. Engineering stable and effective electrode interfaces remains a critical bottleneck. This work introduces a quantum dot (QD)-assisted hot-pressing strategy enabling precise control over the interfacial electric field (IEF) through tailored CsPbBr₃/Cs₄PbBr₆ heterojunctions. Synergistic QDs precursor defect engineering and controlled QD nanocrystals secondary growth during hot-pressing facilitate the formation of heterostructures with tunable phase composition at the interface. Optimized devices feature a thick (101 µm), large-grained (26 µm) orthorhombic CsPbBr₃ absorber integrated with an underlying hexagonal Cs₄PbBr₆ layer. Kelvin probe force microscopy (KPFM) directly verifies a built-in potential step (~21 mV) at the interface, establishing an IEF that cooperates with the Type-II band alignment to effectively suppress dark current injection, restrict ion migration, and promote efficient charge separation. Consequently, the engineered detectors demonstrate an outstandingly low dark current density (0.1 nA cm⁻² at 1 V/mm). The device exhibits dramatically improved carrier transport with an 8-fold enhancement in carrier lifetime (from 1.6 s to 12 s), and clinches a high X-ray sensitivity of 12910 μC Gyair⁻¹ cm⁻² (at 85 V/mm), yet still maintaining the ultra-low dark current baseline. When integrated with a 256 × 256 pixel TFT board, a large area X-ray imaging detector was created, which delivered high resolution and high contrast images for various fine industrial products.
研究领域:
材料科学
·
半导体物理
·
辐射探测
·
纳米结构与器件
·
光电功能材料
·
医学成像
·
工业无损检测
✓ 已验证
产品关联
DOI
PubMed
高影响因子
DESALINATION
·
2025
·
IF 9.8
Jiangjiang Lv,Zhongwei Zhao,Xuheng Liu,Xingyu Chen,Jiangtao Li,Fenglong Sun
With the surging demand for rubidium and cesium, rubidium and cesium extraction resources have gradually expanded from ores to brines to ensure the security of supply of key metals. However, traditional adsorbents of heteropoly salts inevitably suffer from environmental pollution risks, unsustainability, and cumbersome process flows. In this study, potassium phosphotungstate is employed as an ammonium-free adsorbent for sustainably extracting Rb and Cs from salt lake brine. K 3 PW 12 O 40 shows high adsorption capacity (37.71 mg/g for Rb and 60.42 mg/g for Cs) and fast adsorption kinetics (adsorption equilibrium within only 2 min). The adsorbent also exhibits excellent selectivity, with the separation coefficients of Rb/K up to 167.95 and those of Cs/K up to 759.07. It also maintains chemical stability within a broad pH range of 2–10. The desorption efficiency of rubidium and cesium is up to 99.8 % and 85.6 % respectively. After five desorption-adsorption cycles, the adsorption capacity of Rb and Cs remains at 99.8 % and 86.7 % of the initial adsorption capacity. The adsorbent selectively adsorbs Rb + and Cs + from the practical brine even in the presence of a large number of co-existing ions. The Rb and Cs adsorption mechanism for K 3 PW 12 O 40 was primarily ionic exchange with K. The adsorption process provides excellent performance and environmental advantages based on the salt lake industrial cluster. Efficient adsorption performance of Rb and Cs was achieved without the emission of ammonia nitrogen pollutants and the use of ammonium salt chemicals. This study offers a sustainable alternative for extracting Rb and Cs from salt lake brine.
研究领域:
湿法冶金
·
资源可持续回收
·
无机化学
·
环境工程
✓ 已验证
产品关联
DOI
高影响因子
SENSORS
·
2025
·Vol. 25
·期 24
·7462
·
IF 3.5
Yuanyue Lu,Yong Mei,Yingying Gu,Ye Tao,Yuhan Yang,Jiao Yu,Yang Zhang,Lin Liu,Xin Li
An electrochemical immunosensor was fabricated to identify CA15-3, a biomarker for breast cancer (BC). A composite sensor substrate made of “zeolitic imidazolate framework-8” (ZIF-8) and “reduced graphene oxide” (rGO) was chosen and its conductivity was further improved by the addition of chitosan (CS)-doped gold nanoparticles (AuNPs). The CS@AuNPs are able to conjugate with antibodies via the strong Au-S interaction, which offers multiple active sites for antibody immobilization and enhances the sensor performance. This immunosensor is capable of ultrasensitive detection of CA15-3 by specific antigen–antibody –interactions. In healthy people, normal serum CA15-3 is up to 25 U/mL. Under optimized experimental conditions, the alteration in the signal intensity measured by the sensor was related to the CA15-3 activity. The quantitative relationship was linear over 0.001–400 U/mL with a limit of detection (LOD) of 0.0031 U/mL at a “signal-to-noise ratio” (S/N) of 3 and a “correlation coefficient” (r2) of 0.9983. The developed immunosensor showed great accuracy, stability, and selectivity, and was able to detect CA15-3 in human serum samples. These results validate its potential as a reliable analytical platform for BC diagnosis and early clinical screening.
研究领域:
生物传感器
·
肿瘤学
·
电化学
·
纳米材料
·
临床诊断
✓ 已验证
产品关联
DOI
PubMed
高影响因子
APPLIED SURFACE SCIENCE
·
2025
·
IF 6.9
Pengyu Li,Xiaohua Feng,Xiangkui Liao,Shihan Sheng,Axin Huang,Yi Liu,Hua Li
Developing efficient microwave-absorbing coatings via thermal spraying is usually hindered by the thermal demagnetization and oxidation of fillers. Herein, a low-temperature flame spraying strategy is proposed to fabricate Nd-doped BaFe 12 O 19 /nano-carbon spheres (CS)/polyimide (PI) coatings. By systematically controlling the feed rate of the starting feedstock, we precisely modulate filler dispersion and coating microstructure evolution, thereby inducing significant transitions in the dominant microwave attenuation mechanisms. At high feed rates, limited CS addition promotes localized surface plasmon resonance (LSPR) and metallization effects within the surface-dense layer, while excessive CS loading induces an overconnected network and prominent skin effect, impairing microwave absorption (MA) in both cases. Conversely, under low feed rates, favorable thermodynamic and kinetic conditions enable the formation of PI-encapsulated spherical filler structures in the surface region. This unique structure effectively suppresses LSPR and the skin effect, enhances polarization losses, prevents excessive conductivity rise (mitigating impedance mismatch), and thus optimizes over MA. Consequently, the high-feed-rate coating delivers a minimum reflection loss ( RL min ) of−39.1 dB and an effective absorption bandwidth ( EAB ) of 3.7 GHz at a thickness of 4.3 mm. In contrast, the coating with PI-encapsulated spherical filler structures achieves a better RL min of −52.3 dB and a wider EAB of 6.1 GHz at 2.1 mm. Furthermore, the coatings demonstrate outstanding adhesion, achieving Class 0 in the cross-cut testing. Scratch testing demonstrates excellent cohesion and interfacial robustness without catastrophic delamination. The results would give critical mechanistic insight into establishing scalable technical route for engineering flame-sprayed microwave absorbers with simultaneously enhanced structure-function integration and long-lasting mechanical performance.
研究领域:
材料科学
·
微波吸波材料
·
热喷涂技术
·
电磁功能涂层
✓ 已验证
产品关联
DOI
高影响因子
Coatings
·
2025
·Vol. 15
·期 12
·1430
·
IF 2.8
Yu Gao,Xu Zhao,Yilin Xie,Shiyu Yan,Lichun Xiao,Kairong Ding,Jing Cai,Qina Sun
In this study, a novel hybrid adsorbent polydopamine-based nano-zirconium phosphate coated resin (DPZrP) was successfully synthesized, where zirconium phosphate (ZrP) was surface-anchored onto a polystyrene ion-exchange resin (D001) via polydopamine (PDA) mediation. Characterization results indicated that PDA, acting as an interfacial bridge, not only achieved the stable loading of ZrP but also exerted a spatial confinement effect on ZrP through its polymeric cross-linked structure, thereby effectively suppressing the agglomeration of nanoparticles. Compared with pristine D001 and pure ZrP, the hybrid material DPZrP exhibited superior adsorption performance for Cs+. The adsorption capacity of DPZrP for Cs+reached a theoretical maximum of 921.99 mg/g at 333 K. Adsorption kinetic studies indicated that adsorption equilibrium was reached within 120 min, and the reaction rate constant was 1.55 times that of DZrP. The pH effect experiment showed that DPZrP maintained Cs+removal rates of 73.4% and 58.1% under strongly acidic (pH = 2) and strongly alkaline (pH = 12) conditions, respectively. When the molar ratio of Ca2+to Cs+was as high as 64, the Cs+removal rate of DPZrP was 19.3% and 30.4% higher than those of DZrP and D001, respectively. Dynamic column experiments revealed that after treating 2000 bed volumes of simulated wastewater ([Cs+]0= 2.5 mg/L), the Cs+concentration in the effluent remained below 0.5 μg/L, with breakthrough occurring at 3000 BV. After five consecutive adsorption–desorption cycles, the Cs+removal rate of DPZrP remained at 88.4%. These studies confirmed the dispersion effect of PDA on ZrP, and the synthesized DPZrP possessed both rapid capture ability and high adsorption capacity for Cs+. Thus, it provides an efficient adsorbent for the safe purification of nuclear waste liquids.
研究领域:
环境科学
·
材料化学
·
核化学
·
水处理
✓ 已验证
产品关联
DOI
高影响因子
INORGANIC CHEMISTRY
·
2016
·
IF 4.82
Bing-Ping Yang,Chun-Li Hu,Xiang Xu,Jiang-Gao Mao
A new series of platinum iodates, namely, α-(H3O)2Pt(IO3)6, β-(H3O)2Pt(IO3)6, and A2Pt(IO3)6 (A = Na, K, Rb, Cs), have been synthesized. Interestingly, among these six stoichiometrically identical compounds, α-(H3O)2Pt(IO3)6 is polar, whereas other compounds are nonpolar and centrosymmetric. They all consist of zero-dimensional [Pt(IO3)6]2– molecular units separated by H3O+ or A+ cations. All of the lone electron pairs of the IO3– groups are aligned and almost point to one direction for α-(H3O)2Pt(IO3)6, whereas IO3– groups are located trans to each other in other compounds. The material, α-(H3O)2Pt(IO3)6, exhibits very strong second harmonic generation (SHG) effects, approximately 1.2 × KTiOPO4 (KTP), and is phase-matchable. Thermogravimetric analysis, elemental analysis, infrared spectra, UV–vis spectra, nonlinear optical properties, and theoretical calculations are also reported.
研究领域:
材料科学
·
化学
·
光学
✓ 已验证
DOI
PubMed
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2017
·
IF 6.216
Wanjun Mu,Qianghong Yu,Xingliang Li,Hongyuan Wei,Yuan Jian
Efficient, irreversible capture of radioactive strontium and cesium from aqueous media remains a serious task for nuclear waste disposal and environmental protection. To address this task, an effective sorbent based on magnetic composites coated with the synthetic porous exchanger WO 3 was prepared by a facile method and characterized in detail. XRD analysis indicated that the WO 3 coating did not change the phase of the Fe 3 O 4 core, and TEM imaging further showed that Fe 3 O 4 @WO 3 particles were successfully obtained with nearly uniform size. A batch of experiments was carried out to investigate the efficiency of Fe 3 O 4 @WO 3 in removing Sr 2+ and Cs + under various environmental conditions. Experimental results showed that Fe 3 O 4 @WO 3 has higher adsorption capacity for Sr 2+ and Cs + in acidic aqueous solution in comparison to the previous literature. The theoretical maximum adsorption capacities of Fe 3 O 4 @WO 3 for Sr 2+ and Cs + are 44.178 and 53.175 mg g −1 , respectively, as modeled by Langmuir isotherms. The adsorption process is fast and reaches equilibrium within 3 h, which is attributed to the good dispersion of WO 3 on the surface of Fe 3 O 4 and provided much more adsorption sites. Other than Ca 2+ and K + , coexisting electrolyte ions had no significant competition effects on the removal of Sr 2+ and Cs + by Fe 3 O 4 @WO 3 . In addition, the Fe 3 O 4 @WO 3 adsorbent remains stable in acidic solutions and may be repeatedly used 5 times without any noticeable loss in adsorption capacity; the used adsorbents can be easily separated from the aqueous solution using a magnetic method. The advantages of being nontoxic, highly stable, and resistant to acid, as well as having high adsorption capacity for Sr 2+ and Cs + , indicate that Fe 3 O 4 @WO 3 has significant potential for real radioactive wastewater treatment.
研究领域:
化学工程
·
环境科学
·
核能技术
✓ 已验证
DOI
高影响因子
Journal of Environmental Chemical Engineering
·
2022
·
IF 7.968
Bo Gao,Hai-Rong Yu,Hui-Yao Zhang,Ting Liang,Chang-Jing Cheng
As the risk of radioactive waste generated in large quantities is emerging, rapid and selective removal and decontamination of cesium ions (Cs + ) from nuclear waste have become a significant issue for environmental protection and human health. Herein, a novel potassium copper hexacyanoferrate (KCuHCF)-embedded poly(acrylic acid)/laponite (PAAc/Lap-HCF) hydrogel has been developed by a facile and low-cost fabrication route for highly effective and selective Cs + adsorption. The diffusion-derived KCuHCF formation in the nanocomposite hydrogel via layer-by-layer (LBL) assembly can facilitate the preservation of the 3D-interconnected hydrogel structure and the dispersion of KCuHCF particles, which contribute to high-density immobilization of stable KCuHCF (~57.73 wt%) in the matrix. The adsorbent shows enhanced Cs + removal properties in terms of fast kinetics (>90% removal for 20 mg/L of Cs + within 1 h), stability (>115 mg/g in wide pH value of 2–11), high adsorption capacity (146.22 mg/g) and selectivity ( K d = 1.3 ×10 5 mL/g, 1 mg/L Cs + in highly competitive seawater). Such excellent characteristics with fast kinetics are mainly due to the high ion accessibility from the inherent nature of hydrogels and the highly loaded KCuHCF particles in the composites. The adsorption kinetics and isotherm obey the pseudo-second-order model and the dual-site Langmuir adsorption model, respectively. This nanocomposite hydrogel prepared in our work shows enhanced performance on removal of Cs + in aqueous solution, which has a good application prospect in treating radioactive wastewater .
研究领域:
环境科学
·
材料科学
✓ 已验证
DOI
高影响因子
危险品化学品经营许可证（带存储）