FOOD CONTROL
·
2026
·
IF 7
Dandan Yan,Yifei Ding,Xin Wang,Weiyu Qiu,Yufeng Xu,Huadong Du,Yanan Sun
The short shelf life and high susceptibility to spoilage of fresh-cut fruits present a major challenge for the food industry. To address this, D-glutamic acid-functionalized Forsythia suspensa carbon dots (D/F-CDs) were synthesized via a hydrothermal method. The obtained D/F-CDs exhibited abundant surface functional groups and optical properties. Antibacterial assays revealed potent activity, with inhibition rates exceeding 90% against Escherichia coli (E. coli) and 96% against Staphylococcus aureus (S. aureus) at 10 mg/mL. Mechanistic studies indicated that the bactericidal action originated from membrane disruption and cytoplasmic leakage. By incorporating D/F-CDs into a konjac glucomannan (KGM) and apple pectin (AP) matrix, an antimicrobial coating (D/F-CDs@KGM/AP) was prepared. Furthermore, rheological measurements demonstrated that D/F-CDs treatment altered the viscosity and viscoelastic moduli. The D/F-CDs 3 @KGM/AP coating not only effectively maintained the moisture and overall quality of fresh-cut kiwifruit during storage but also kept the total viable count (TVC) at only 4.73 log CFU/g on day 9. Consequently, the D/F-CDs 3 @KGM/AP coating represents a promising antibacterial strategy for maintaining the quality of fresh-cut kiwifruit.
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高影响因子
JOURNAL OF FOOD SCIENCE
·
2025
·Vol. 90
·期 9
·e70533
·
IF 3.4
Ran Feng,Xin-Yue Liu,Rui-Cheng Xu,Bao-Cai Xu,Han Tao,Bao Zhang
Konjac glucomannan (KGM) exhibits superior water absorption, gelation, and emulsification properties, as well as health benefits due to its indigestible fiber content. This study aims to dig into the skeleton role of KGM (0.3–1.5%) on structure formation, water retention, and stability of emulsion gel constructed with pea protein isolate-octenyl succinic anhydrate corn starch (PPI/OSA-CS) composite. Emulsion gels containing increased KGM exhibited densification in the gel network, and 1.2–1.5% KGM showed ideal network structure without voids. Besides, emulsion gels containing 1.5% KGM showed the highest viscosity and viscoelasticity (e.g., elastic modulus 945 Pa compared to the control group (0.2 Pa) within the linear viscoelastic region (LVR)), indicating the formation of a stable protein network. The water retention, freeze-thaw stability, and thermal stability of the emulsion gel were also improved. The findings provide insights into the use of KGM to keep activity of the biological molecules in the emulsion gel as potential animal fat simulators.
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高影响因子
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2026
·
IF 8.5
Xuening Ren,Wen Zhang,Minshen Liu,Jixiang Ge,Hong Yang,Guiliang Chi
Probiotics play a critical role in maintaining human health homeostasis, yet their oral delivery faces challenges due to poor gastrointestinal survival, uncontrolled release, and inefficient targeted colonization. To address these limitations, we developed colon-targeted mucoadhesive (sCS-BC)/OKGM-SA microspheres using a W1/O/W2 double emulsion technique combined with ionic crosslinking, employing oxidized konjac glucomannan (OKGM), thiolated chitosan (sCS), and bacterial cellulose (BC). In vitro digestion assays revealed that the microspheres effectively shielded probiotics under simulated gastric and bile salt, while enabling pH- and enzyme-responsive release in the intestinal, achieving a viable probiotic count of 1.5 × 10 8 CFU/mL. Rheological characterization and in vivo gastrointestinal transit studies demonstrated that the microspheres enhanced colonic colonization through interactions with the intestinal mucus layer. Histological analysis further indicated that the microspheres stimulated colonic goblet cell proliferation and mucus layer formation. Metagenomic and metabolomic profiling confirmed that oral administration of the probiotic-loaded microspheres markedly enriched gut microbial diversity and helped preserve intestinal barrier integrity, showing potential in modulating gut immune function. The (sCS-BC)/OKGM-SA system integrates upper gastrointestinal protection, colon-targeted delivery, mucus adhesion, and probiotic proliferation, offering a novel strategy for targeted probiotic delivery. This work establishes a foundational framework for designing next-generation colon-targeted probiotic carriers and underscores their therapeutic promise in modulating intestinal ecosystems.
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高影响因子
RSC Advances
·
2026
·Vol. 16
·期 1
·370-382
·
IF 4.6
Lan Ma,Pengyu Hu,Yihao Zhang,Yunchuan Dai,Yanzhu Guo
Biodegradable and edible packaging films derived from konjac glucomannan (KGM) are gaining popularity as promising candidates to replace petroleum-based plastics with the aim of alleviating environmental problems. However, their poor mechanical strength and lack of antioxidant activity have restricted their practical application in food packaging. Bacterial cellulose (BC), with a three-dimensional nanostructure and biodegradable and biocompatible properties, was chosen as a reinforcing agent to enhance the mechanical properties of KGM film. Film prepared with 15% BC displayed the highest tensile strength of 62.87 MPa and elongation at break of 38.17%, owing to the strong hydrogen bond interactions between the BC and KGM chains. Furthermore, tea polyphenols (TP), a type of natural antioxidant agent, were incorporated into the BC and KGM composite films and endowed films with excellent antioxidant properties, with scavenging rates toward DPPH and ABTS free radicals of up to 96.74% and 97.50%, respectively. Meanwhile, the mechanical strength, UV shielding performance, and water-vapor and oxygen barrier properties of the films were also improved through the incorporation of TP. The film was successfully applied as a packaging material for fresh-cut apple preservation. The prepared film demonstrated nontoxicity and excellent biodegradability over 28 days, with no significant impact on plant growth. Therefore, the prepared composite film exhibited great prospects as a novel type of biodegradable, sustainable and bioactive film for food preservation.
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INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2026
·
IF 8.7
Kangdi Cao,Zhiyuan Yin,Ningfei Duan,Zhiguo Zhang
Wet-heating Maillard conjugation improved FPC solubility and stability. • CG and KGM induced distinct structural changes in Mucor FPC. • FPC-CG showed greater functional improvement than FPC-KGM. • The 20:3 FPC/polysaccharide ratio gave the best overall performance. Fungal protein concentrate (FPC) is a promising sustainable protein ingredient, but its poor solubility and limited interfacial stability restrict its food applications. In this study, Mucor-derived FPC was conjugated with cassia gum (CG) or konjac glucomannan (KGM) by wet-heating Maillard reaction at different mass ratios. Compared with native FPC and physical-mixture controls, both conjugates showed evident structural modification and improved functionality, with the best overall performance at an FPC/polysaccharide ratio of 20:3. At this ratio, the degree of glycation reached 38.86% for FPC-CG and 29.62% for FPC-KGM, while surface hydrophobicity decreased from 254.68 to 146.11 and 179.43, respectively. Intrinsic fluorescence showed red shifts from 315 nm to 318 nm (FPC-CG) and 319 nm (FPC-KGM), and ordered secondary structure decreased by 12.20% and 10.54%, respectively. These structural changes were associated with enhanced solubility, emulsifying properties, foam stability, water- and oil-holding capacities, and DPPH radical-scavenging activity. Overall, CG produced stronger improvements than KGM, indicating that polysaccharide structure is critical for designing functional fungal protein-polysaccharide conjugates.
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INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2022
·
IF 8.025
Xiangyu Wei,Chunyan Cui,Chuanchuan Fan,Tengling Wu,Yuan Li,Xiaoping Zhang,Kuan Wang,Yudi Pang,Puqing Yao,Jianhai Yang
Hemostasis and prevention of postoperative adhesions after hepatectomy are still challenges. In this work, we chose chitosan, a competitive candidate hemostatic material, as the backbone, and konjac glucomannan as the functional moieties, to form an injectable hydrogel. The hydrogel was prepared by the Schiff base reaction of dodecyl-modified N -carboxyethyl chitosan (DCEC) and oxidized konjac glucomannan (OKGM), which could effectively prevent bleeding and postoperative adhesions. The resultant hydrogel possessed self-healing and tissue adhesive capability, and combined the unique bioactivities of two polysaccharides: DCEC endowed the hydrogel with excellent antibacterial and hemostatic ability by the electrostatic and hydrophobic interactions between the cell membrane and amine/dodecyl groups, and OKGM imparted hydrogel anti-inflammatory action by activating macrophages. Moreover, the notable hemostatic efficacy of the hydrogel was confirmed in a rat hepatectomy model. The hydrogel could prevent postoperative adhesions and down-regulate the inflammatory factor TNF-α and the pro-fibrotic factor TGF-β 1 in situ, which might be caused by the combination of the barrier function of hydrogel and instinct bioactivities of DCEC and OKGM. Thus, this multifunctional injectable hydrogel is potentially valuable for preventing bleeding and postoperative adhesions after hepatectomy.
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EUROPEAN POLYMER JOURNAL
·
2023
·
IF 6
Yuqian Wu,Weijie Xu,Jianliang Li,Zhangfeng Zhong,Liqing Huang,Shengke Li,Huaping Tan
Dynamic Schiff base-mediated natural polysaccharide hydrogels are often griped about rapid degradation as biological scaffolds, which is desirable for an efficient method to improve their stability. Herein, tannic acid (TA) was employed to further entangle Schiff base crosslinked hydrogel (CSGM) composed of carboxymethyl chitosan (CMCS) and oxidized konjac glucomannan (OKGM) to achieve tunable degradation and drug release of the obtained CSGM@TA hydrogel. As examined by SEM, the porous structure of CSGM hydrogel became denser after being immersed in TA solution, and the average pore size of CSGM hydrogel was decreased from 108.0 μm to 60.0 μm along with TA amount in CSGM@TA hydrogel. The degradation rate of CSGM hydrogel was remarkably inhibited upon entanglement by TA. CSGM@TA-3 with highest TA amount was found stable in PBS (pH 5.5) after 14 days, whereas ∼ 50 % of CSGM hydrogel was remained under same condition. The release of TA from CSGM@TA hydrogels was also examined under different pH, and the total TA release from three CSGM@TA hydrogels was 10 %–19 % within 14 days at pH 5.5, whereas the value was remarkably increased to 35 %–45 % at pH 7.4, suggesting a pH-dependent TA release behavior controlled by pH-responsive Shiff-base bonding and TA-CSGM bonding. Meanwhile, CSGM@TA hydrogels were found to possess good antioxidant, antibacterial, and anti-biofilm capabilities, demonstrating great potential as multifunctional scaffolds for tissue engineering and wound healing.
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FOOD HYDROCOLLOIDS
·
2023
·
IF 10.7
Cikun Liu,Lishi Wang,Han Chen,Pei Gao,Yanshun Xu,Wenshui Xia,Shao-Quan Liu
Pickering emulsions fabricated by tailoring protein-polysaccharide complexes have attracted increasing attention. In this study, surimi particles (SPs) and konjac glucomannan (KGM) were utilized to prepare Pickering emulsions via one-step or layer-by-layer methods. Firstly, SPs and SPs-KGM particles were prepared and characterized, then the interfacial structures and stability including storage, heating, freeze-thawing (FT) of Pickering emulsions were determined. Results showed that introduction of KGM could not cause phase separation of the SPs suspension (aqueous phase) within 24 h at 4 °C, which might relate to the entanglement structures, hydrogen bonding and weak charge repulsions between SPs and KGM. According to microstructure images, the KGM with linear chains enabled SPs based Pickering emulsions possessing small droplets, and these droplets coated with a uniform and dense interface layer. Moreover, the KGM combined with SPs endowed both the Pickering emulsions and interfacial layers with superior viscoelastic properties. After 14 days of storage at 4 °C, the stability index of Pickering emulsions with SPs and KGM reached 100% regardless of the mixing methods. Unlike the poor stability of single SPs stabilized emulsions, the emulsions prepared with SPs and KGM remained comparatively stable under heating and FT conditions. In conclusion, the KGM improved the interfacial properties of SPs stabilized Pickering emulsions whether using one-step or layer-by-layer approach, further promoting the processing stability of these systems.
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JOURNAL OF MATERIALS SCIENCE
·
2020
·Vol. 55
·期 27
·12884-12896
·
IF 3.553
Luo Zirong,Li Dandan,Huang Langhuan,Tan Shaozao,Huang Jiwei
Nowadays, the harm caused by the leakage of oil and dangerous organic solvents to the ecological environment and human health cannot be ignored, and effective treatment measures are urgently needed to alleviate the current situation. Therefore, the development of low-cost and efficient adsorbents is the key to solve the problem. In this paper, konjac glucomannan was used as flexible skeleton. Flexible aerogel based on an interpenetrating network of konjac glucomannan and reduced graphene oxide was prepared by two-step hydrothermal method. On this basis, the composite aerogel was superhydrophobically modified to improve its adsorption selectivity. A series of characterization results showed that the adsorbent had flexible three-dimensional porous structure, excellent mechanical properties, adsorption selectivity, recyclability and biodegradability. At the same time, the composite aerogel synthesized by a simple and environmentally friendly method could realize the continuous separation of oil and water by vacuum pump. It showed that its application in the field of high-efficiency oil–water separation had a broad prospect.
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LWT-FOOD SCIENCE AND TECHNOLOGY
·
2024
·
IF 6
Xuehui Li,Chen Zhang,Changrui Liu,Weiqi Luo,Ying Wang,Libin Wang,Norhafizah Abdullah
Post-harvest mangoes are prone to spoilage, and volatiles change accordingly. Konjac glucomannan phosphate composite film (KGMP), as an environmentally friendly polysaccharide-based material, has been shown to possess good film-formation, stability, antibacterial activity, and water vapor permeability. However, the impact of KGMP on the quality and aroma of mangoes during storage remains unclear. Therefore, KGMP was used to coat mangoes before and after harvest. Results indicated that KGMP delayed weight loss, the decline in firmness, and the deterioration of color difference. It also delayed the accumulation of total soluble solids, increased titratable acidity, limited ethylene evolution, and altered aroma quality. A total of 39, 40, and 31 volatiles were detected in JinHwang, Keitt, and Ivory, respectively. Changes in their contents were correlated with ethylene evolution. Although KGMP altered the formation of over 70% of mango volatiles, it had little effect on the total volatile abundance. Pre-KGMP treatment had a more pronounced inhibitory effect on volatile abundances but the increase of key volatiles like ethyl acetate, propyl propanoate, ethyl hexanoate suggested that KGMP treatment could enhance certain flavor characteristics while potentially extending the shelf life. Volatiles such as α-terpinene, diallyl disulfide, and α-phellandrene played key roles in differentiating mangoes under different conditions.
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INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2025
·
IF 8.5
Jie Yan,Suwen Yang,Jianshan Chen,Xianzhang Wu,Yan Qing
In all soft actuators, achieving both outstanding mobility and capturability is crucial; however, these properties are usually mutually exclusive due to the lack of an effective mechanism for controlling the viscoelasticity of the switching polymer matrix while maintaining a moderate surface adhesion. In this study, we propose a dynamic bond cross-linking strategy to successfully develop a magnetically responsive soft hydrogel (MRSH) with exceptional mobility (117.56 mm/s) and capturability. By introducing dynamic B O bonds into the KGM@Fe 3 O 4 @PSSMA NPs composite matrix, the crosslinking density and overall cohesion of MRSH can be precisely controlled, resulting in unique non-Newtonian fluid characteristics. Additionally, the dynamic B O bonds transition between associative and dissociative states with the hydroxyl groups on the KGM molecular chains, which can effectively regulate the amount of hydroxyl groups on the surface of MRSH, thereby achieving demonstrate moderate surface adhesion. As a result, the synthesized MRSH exhibits remarkable capturability on various target surfaces and maintains outstanding mobility, even in underwater environments. This work paves the way for new possibilities in the field of soft actuators and engineering by overcoming the limitations of traditional soft actuators in terms of surface adhesion and responsiveness through innovative structural design and material combinations.
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CARBOHYDRATE POLYMERS
·
2011
·
IF 3.463
Quan Li,Bing Xia,Mickey Branham,Wei Ha,Hao Wu,Shu-Lin Peng,Li-Sheng Ding,Bang-Jing Li,Sheng Zhang
The self-assembly of rod–coil carboxymethyl konjac glucomannan-graft-poly(ethylene glycol) (CKGM- g -PEG) and α-cyclodextrin (α-CD) complexes were investigated and used as encapsulating hollow nanospheres for the enzyme glucose oxidase (GOX) in aqueous solution. These hollow nanospheres exhibited “cell-like” semi-permeability allowing enzyme substrates to pass through the surface while restricting the encapsulated enzyme (i.e. GOX) to the interior. Encapsulated GOX exhibited higher thermostability , optimal enzymatic activity over a wider pH range and improved storage stability in comparison to free un-encapsulated GOX. In addition, these CKGM- g -PEG/α-CD hollow nanospheres showed in vitro biocompatibility when exposed to L929 cells when tested using MTT viability assay. These studies suggested that self-assembly of CKGM- g -PEG and α-CD to form stable nanospheres may be an effective method for enzyme encapsulation with numerous biomedical applications.
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