SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
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2025
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IF 4.6
Lin-Lin Zhang,Zeng Chen,Li Li,Wuying Yang,Dan Wang,Yanping Hong,Kaijie Tang,Jiaxin Hong,Lu-Ying Duan,Limin Lu
Developing a multifunctional sensor that can detect food-related multi-analytes is significant for food safety but remains challenging due to the difficulty of integrating multiple functions into one sensor. Herein, a dual-luminescent europium metal-organic framework (EuMOF) was elaborately synthesized through a simple self-assembly process, during which Eu 3+ coordinated with 2-hydroxyterephthalic acid (HTPA) and 1,10-phenanthroline that delivered strong characteristic fluorescence of HTPA and Eu 3+ . The resultant EuMOF exhibited good detection performance toward Sn 4+ and amitraz with different response behaviors. As for target Sn 4+ , the remarkably enhanced fluorescence from HTPA was observed and the fluorescence for Eu 3+ decreased significantly, which was attributed to the structural disintegration of EuMOF caused by Sn 4+ . Whereas, the presence of amitraz weakened both luminescence of HTPA and Eu 3+ owing to the synergistic function of inner filter effect and photoinduced electron transfer. Furthermore, an intelligent and miniature sensor that incorporated EuMOF-based test paper with color recognition application was exploited for portable visual analyzing Sn 4+ and amitraz in real samples, affording great possibilities for on-site monitoring of food hazards.
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PubMed
高影响因子
TALANTA
·
2020
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IF 5.339
Qiuju Zhou,Yajun Fang,Jiayu Li,Dan Hong,Panpan Zhu,Shihong Chen,Kejun Tan
In this work, a novel dual-ratiometric optical probe based on europium-doped carbon dots (Eu-CDs) was developed for colorimetric and fluorescent visual sensing dipicolinic acid (DPA), a anthrax biomarker. Eu-CDs with recessive signals were prepared via thermal pyrolysis method. And the magenta appears when Eu-CDs coordinates with Eriochrome Black T (EBT). Based on the ligand displacement strategy, DPA reduces magenta and makes blue appear, which develop ratiometric colorimetric visual detection methods of DPA. Under 270 nm excitation, DPA make the red fluorescence signal of Eu in EBT-CDs@Eu appear, based on the absorbance-energy transfer-emission effect, the ratiometric fluorescent visual detection assay of DPA has been developed. Based above, dual-ratiometric optical probe was designed successfully. The limit of detection (LOD) is 10.6 nM for ratio colorimetric assay . More prominently, naked-eye determination of DPA without instrument is as low as 1.0 μM. Furthermore, its practicability was verified by quantifying the DPA in Bacillus subtilis spores and human urine (with RSD≤2.35%). The sensor shows great superiority in on-site analysis of DPA, especially in limited instruments conditions.
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高影响因子
TALANTA
·
2023
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IF 6.1
Xiaoqin Shen,Bing Yan
The application of covalent organic frameworks (COFs) in fluorescence detection is of great interest. Herein, we have synthesized the ionic covalent organic framework TGH + ·PD: Eu(TTA) 4 with the characteristic emission of lanthanides by a straightforward ion-exchange method. This is the first time that aristolochic acid A (AA), a key biomarker for absorption and metabolism in the body for early diagnosis of diseases, has been detected by using COF as a fluorescent probe , which exhibits a good linear correlation with the AA concentration over a range from 5.0 to 1000 μM with a detection limit of 0.0808 μM. In addition, the selective response to sulfamethoxazole (SMZ)/trimethoprim (TMP) is achieved by varying the excitation wavelength with detection lines of 30.2 nM and 2.898 μM, respectively. It is worth mentioning that BNPP has been developed for the accurate determination of SMZ in uncertain samples. In a word, the prepared TGH + ·PD: Eu(TTA) 4 -based sensor can be used for the quantitative detection of AA and SMZ/TMP, separately, effectively extending the application of COFs in the field of fluorescence sensing.
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PubMed
高影响因子
ANALYST
·
2024
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IF 3.6
Xinyue Qian,Cheng Tan,Jing Zhang,Kang Wu,Anping Deng,Jianguo Li
The “antenna effect” is one of the most important energy transfer modes in lanthanide light-emitting polymers. In this study, novel luminescent nanostructured coordination polymers (Eu–PCP) were synthesized in one step using Eu3+ as the central metal ion and 5,10,15,20-tetrakis (4-carboxyphenyl) porphyrin (TCPP) as the organic ligand. The unique “antenna effect” observed between Eu3+ and TCPP leads to a substantial improvement in the electrochemiluminescence (ECL) emission efficiency. Eu–PCP exhibits good cathodic ECL characteristics. Additionally, Au@SnS2 nanosheets exhibit favorable electrical conductivity, biocompatibility, and a significant specific surface area. This makes them a suitable choice as substrate materials for the modification of electrode surfaces and capturing antigens. Being well known, the development of sensitive and rapid methods to detect chloramphenicol is essential for food safety. Based on this, we report a novel competitive electrochemiluminescence immunoassay to achieve ultra-sensitive and highly specific detection of chloramphenicol. The linear range was 0.0002–500 ng mL−1 and the detection limit was 0.09 pg mL−1. Apart from that, the experimental results proved that it provided a new analytical tool for the detection of antibiotic residues in food safety.
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高影响因子
Applied Materials Today
·
2024
·
IF 7.2
Xiuhong Huang,Liqin Zheng,Pengfei Li,Ziling Lin,Shaohong Huang,Changren Zhou
Bone defects have been a tough clinical challenge. The natural trabecular tissue reflects a balance between the minimal metabolic cost of maintenance and maximal network stability, with mitochondria being the energy suppliers for osteogenesis. Herein, a 3D printed trabecular bone-templated scaffold composed of polylactide (PLA) modified with europium (III)-organic ligands (polydopamine and chitooligosaccharide, PDA/COS@Eu) was fabricated (denoted as Tra-PLA/PDA/COS@Eu) to augment bone repair by facilitating mitochondrial function. First, the trabecular bone templated-scaffold provides superior mechanical performance and permeability in contrast to a computer aided designed (CAD) scaffold under a same volume fraction. Tra-PLA/PDA/COS@Eu scaffold up regulated PI3K/AKT/S6K/HIF-1α pathway and significantly promoted BMSCs proliferation and osteogenic differentiation. In addition, Tra-PLA/PDA/COS@Eu scaffold provided anti-inflammatory environment by promoting macrophages M2 polarization through COS, and significantly stimulated BMSCs osteogenesis with enhanced mitochondrial function and biosynthesis. Remarkably, Eu ions are the key ingredient in enhancing mitochondrial function and biosynthesis in BMSCs. Further studies showed that the above-mentioned facilitations in a rabbit bone defect model were found to be more significant with trabecular bone-templated scaffolds, as opposed to CAD scaffolds. In summary, this novel trabecular bone-templated scaffold targeting mitochondrial function has the potential to become an effective method in the treatment of large bone defects.
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JOURNAL OF LUMINESCENCE
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2021
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IF 3.599
Lei Jia,Xiangzhen Chen,Jun Xu,Lina Zhang,Xiyan Dong,Dan Zhao,Ning Bi,Taofeng Zhu,Tongqian Zhao
It is of vital significance to achieve accurate real-time detection of tetracycline (TC). In this research, the ratio fluorescence detection of tetracycline is realized by introducing europium-based aminoclay containing carbon dots with good sensitivity to tetracycline through subsequent surface modification. With the increase of tetracycline concentration, the fluorescence intensity of rare earth europium fluorophore increases continuously, while the fluorescence intensity of CDs is basically unchanged. The CIE chromaticity coordinate confirms that the luminous color of the probe can be adjusted continuously from blue to red. The results exhibit this approach owns the favourable linearity to TC within 0–12.5 μM and 10–25 μM, and the high sensitivity with a low detection limit of 3.133 nM. Moreover, it can entirely satisfy the requirements of field detection because the rapid monitoring time as short as 30 s. The multicolor fluorescence detection strategy is reliable and feasible in the field test of TC in various actual samples. In addition, a TC floating detector based on vertical float structure is designed to achieve the rapid visual detection of TC in simulated flow environment. The superiority of the sensing platform opens up a neo-pathway for point-of-care monitoring of TC residues.
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DYES AND PIGMENTS
·
2020
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IF 4.613
Sujie Han,Xipao Chen,Yaoping Hu,Lei Han
As a newly discovered photoluminescent material, carbon dots (CDs) have shown promising performance in many fields. However, due to aggregation-caused fluorescence quenching, most of CDs are poorly emissive in the solid state, which severely restricts their wide applications, especially in the optoelectronic devices . To overcome this problem, herein, we design a novel kind of self-quenching-resistant N , P -doped CDs, using polyethyleneimine (PEI), phosphoric acid , and ethanol as raw ingredients. The as-synthesized CDs are amorphous and contain abundant surface PEI chains which properly separate the individual carbon core and prevent the direct π–π interaction. Such a unique structure conquers self-quenching during aggregation, and gives CDs a bright blue fluorescence in solid state without any other additional matrices. By taking advantage of their excellent optical properties , the CD powers, combined with red emissive europium metal-organic frameworks, are successfully employed as hybrid phosphors for construction of white light-emitting diodes exhibiting a Commission Internationale de L'Eclairage (CIE) coordinate of (0.33, 0.33).
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SENSORS AND ACTUATORS B-CHEMICAL
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2021
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IF 7.46
Yijian Zhao,Qinzhi Wang,Haihua Wang,Hui Zhangsun,Xinyu Sun,Tong Bu,Yingnan Liu,Wenze Wang,Zhihao Xu,Li Wang
The misuse of tetracycline (TC) will cause adverse effects on environment and has become a serious problem threatening human health. In this work, a novel bifunctional europium-based metal organic framework ( 1 ) containing characteristic metal chains was successfully synthesized via a facile one-pot hydrothermal method for the first time and used in simultaneous detection and removal of TC. Detailed characterizations including scanning electron microscope, energy dispersive X-ray spectroscope, Fourier-transform infrared, X-ray diffraction and X-ray single crystal diffraction were conducted to confirm the successful synthesis of 1 . Subsequently, the prepared 1 showed significant fluorescence enhancement at 615 nm with a wide sensitive range (0.05–60 μM) and low detection limit (3 nM) for detection of TC under pH 9. The excellent adsorption behaviours (387.14 mg g −1 ) of 1 toward TC were demonstrated by kinetic and equilibrium experiments. Possible mechanisms of recognition and adsorption including host-guest capability of Eu nodes, hydrogen bonding, π-π interactions and electrostatic attraction were further explored. In addition, the practical feasibilities of 1 for TC sensing were further investigated in real samples with satisfactory recoveries (94.89 %−112.86 %, RSD ≤ 6.03 %). This work provides a facile strategy for design of MOF-based bifunctional turn-on fluorescence sensor for efficient TC monitoring.
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Advanced Science
·
2026
·
IF 14.1
Bingqian Wang,Yuping Zhang,Xiaoning Su,Ning Liu,Hui Zeng,Bo Yang,Yang Xue,Fang Guo,Changkui Liu
Titanium alloy scaffolds (Ti–6Al–4 V) are widely used to repair bone defects. However, conventional titanium-based implants lack customized functional surface interfaces that promote coordinated local nerve and blood vessel regeneration, thereby limiting bone regeneration and long-term stability. To address this limitation, we utilize a topologically optimized triple-periodic minimal surface (TPMS) porous titanium (Ti) scaffold. Polydopamine (PDA) surface engineering is used to stably immobilize europium ions (Eu 3+ )-coordinated black phosphorus (BP) nanosheets onto the surface, forming a Ti–PDA@(BP+Eu) (TPBE) scaffold with photothermal-ionic synergistic release to coordinate early neurovascular reconstruction and subsequent bone regeneration. In vitro studies demonstrate that under periodic near-infrared irradiation, the TPBE scaffold enables on-demand release of Eu 3 + /phosphate ions (PO 4 3− ), thereby promoting adhesion, migration, differentiation, and gene expression of neural, vascular, and osteogenic cells. Further, activating the PI3K/Akt pathways enhances neurite outgrowth and axonal regeneration of rat adrenal pheochromocytoma cells. In vivo large-segment bone defect models demonstrate that TPBE scaffolds combined with mild photothermal therapy increases neurovascular network density and upregulate osteogenic–neuro–vascular coupling factors, thereby accelerating bone regeneration. This study presents an innovative method for the fabrication of Ti-based implant materials capable of cascade regeneration of nerve, vascular, and bone tissues, establishing the basis for the exploration of multitissue regenerative biomaterials.
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FOOD CHEMISTRY
·
2024
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IF 8.5
Zheng Cheng,Xinfang Liu,Beibei Zhao,Xu Liu,Xiaorui Yang,Xiaoyu Zhang,Xun Feng
The on-site detection of mancozeb in food samples holds immense value for food safety. A red-fluorescent europium complex ( Eu-PYDC-Phen ) has been prepared and employed as a fluorescence probe for mancozeb detection. The optimized probe suspension exhibits excellent detection performances, including a wide linear range (0–0.24 mM), low detection limit (65 nM), rapid response (2 mins) and high selectivity . Moreover, a portable detection platform was carefully designed, integrating the Eu-PYDC-Phen -based fluorescent test strips with smartphone color recognition software. This innovative platform enables visual and on-site detection of mancozeb in tomato, apple, and lettuce, achieving satisfactory recovery rates (90.34 to 106.50%). Furthermore, the integration of machine learning techniques based on hierarchical clustering algorithm has the potential to further improve the prediction and decision-making efficiency in mancozeb detection. This work provides an economical, convenient, and reliable strategy for on-site detection of pesticide in agricultural products, thereby making a meaningful contribution to food safety.
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高影响因子
MICROCHEMICAL JOURNAL
·
2025
·
IF 5.1
Zhaofeng Wang,Hui Xu,Lihua Wang,Xinxiang Zheng,Tengzhi Zhao,Bowen Qu,Hua Wang
The persistent residues of tetracyclines (TCs), particularly tetracycline (TC) and oxytetracycline (OTC) in aquaculture have attracted widespread attention due to their significant threat to the environment and human health. Therefore, there is an urgent need to develop facile and highly sensitive methods to detect TC and OTC. In this study, using biomass carrot as the carbon source, polyethyleneimine as the nitrogen source, nitrogen-doped carbon dots (W-CDs) were prepared by one-pot hydrothermal method. Subsequently, a ratiometric fluorescent probe was constructed by combining W-CDs with europium ions (Eu 3+ ), enabling the specific recognition of TC and OTC. Based on the opposite response signals, W-CDs/Eu 3+ enables the ratiometric detection of TC in a wide linear range of 0.0067–25 μM and OTC from 0.0067 to 21 μM, with a sensitive detection limit down to 2.96 nM and 2.85 nM, respectively. Moreover, under 365 nm ultraviolet (UV) lamp, the color change from blue to red is clearly observed. Furthermore, the smartphone-assisted sensing platform enables both visual and quantitative detection of TC. The method was successfully applied to detect TC and OTC in actual water samples, demonstrating the promising potential of this probe.
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SENSORS AND ACTUATORS B-CHEMICAL
·
2024
·
IF 8
Yishan Li,Xiaohong Tan,Shaoru Wu,Wenping Hong,Jiamin Luo,Shanshan Zhao,Libo Sun,Jinming Lin,Qiang Chen,Maosheng Zhang
Organic-inorganic halide perovskite nanocrystals (PNCs) have been extensively utilized in the field of sensing, attributed to their superior optoelectronic properties, including high photoluminescence quantum yield, tunable band gap, and narrow full width at half maximum. However, the majority of sensors based on PNCs have traditionally relied on a single fluorescence signal emission and its intensity variations, leading to limitations in visualization resolutions. Hence, we developed a rapid, sensitive, and visually discernible dual-emission ratiometric fluorescence sensor for the detection of methylamine (MA) gas that based on the in situ formation of methylamine lead bromide (MAPbBr 3 ) PNCs within europium metal-organic frameworks (Eu-MOFs) in the ambient atmosphere. In this strategy, Eu-MOFs not only served as the protective matrices to enhance the stability of MAPbBr 3 PNCs but also as luminescent materials in ratiometric fluorescence sensing, owing to their exceptional luminescent properties. More importantly, benefiting from the excellent gas adsorption properties and protective abilities of MOFs, the proposed sensor demonstrates higher sensitivity, stability, and reproducibility. Experimental results indicated a good linear correlation with MA concentrations ranging from 9.0 to 90.0 ppm, achieving a limit of detection as low as 1.0 ppm. In comparison to other reported methodologies, this approach demonstrates a remarkably short response time of 20 seconds.
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