Journal of Thermal Science
·
2026
·
IF 3.2
Cheng Xianzhi,Wu Lingnan,Jin Kairu,Yu Xupeng,Lei Jieming,Zhu Quan,Abudoureheman Maierhaba,Wei Bo,Tian Zhenyu
Pyridine is an important and typical model compound for studying fuel-nitrogen conversion mechanisms during the combustion process. Blending a part of ammonia during the coal combustion process could effectively reduce CO 2 emissions. The co-oxidation kinetics of pyridine and ammonia were investigated in an atmospheric pressure jet-stirred reactor at temperatures between 770 and 1100 K with the equivalence ratios of 0.05 and 2. Pyridine, ammonia, and several major oxidation products were quantitatively measured by two gas chromatographs and a Fourier transform infrared spectrometer. The pyridine LTO 3.0 kinetic model was used to predict the pyridine-ammonia conversion characteristics. The current model could provide relatively good predictions of pyridine conversion under most conditions, including pyridine-ammonia co-oxidation under fuel-rich conditions, but the predictions for NH 3 under fuel-rich conditions and pyridine under fuel-lean conditions still require improvement. Blended ammonia promotes pyridine consumption under fuel-lean conditions and inhibits pyridine consumption under fuel-rich conditions. The results of this work could help better understand the coal-ammonia interaction during the co-firing process of coal and ammonia.
✓ 已验证
DOI
高影响因子
MICROCHIMICA ACTA
·
2026
·Vol. 193
·期 5
·296
·
IF 5.4
Chen Jiaming,Zhang Yue,Zhang Linfeng,Zhang Siqi,Song Wei
An efficient galvanic replacement synthesis strategy for the preparation of a bimetallic Ni 2 Pd 1 aerogel with remarkable peroxidase-mimicking activity is presented. By employing a non-precious Ni aerogel as a structural template, the precious Pd component is successfully incorporated and alloyed within its three-dimensional (3D) porous network through rational interfacial design. The combination of the intrinsic through-pore structure of metal aerogels with optimized bimetallic composition results in significantly enhanced peroxidase-like performance. Investigations involving radical quenching/trapping experiments and electrochemical tests confirm that the catalytic mechanism proceeds via an electron transfer pathway. Furthermore, based on the specific inhibitory effect of L-cysteine on the catalytic behavior of optimized Ni 2 Pd 1 alloy aerogel, a highly selective colorimetric sensing platform is developed, achieving a detection limit of 1.43 µM and robust anti-interference capability against various common amino acids. This study provides new design concepts and technical pathways for developing high-performance biomimetic sensing materials.
Section
Graphical abstract
✓ 已验证
DOI
PubMed
高影响因子
Advances in Manufacturing
·
2026
·
IF 3.9
Wang Yi-Fei,Han Xiao-Xiao,Zhu Xiao-Long,Zhu Wei,Chen Feng
Part sedimentation in volumetric additive manufacturing (VAM) technology is a well-known detrimental effect that can significantly deteriorate printing resolution and shape fidelity. This study reveals the underlying mechanism by which process parameters and material properties affect the sedimentation properties of parts fabricated by VAM, considering the intrinsic thermal process and its interaction with polymerization kinetics. It was found that thermally induced changes in material viscosity and polymerization parameters played an essential role in regulating sedimentation behavior. Lowering the ambient and initial printing temperatures can increase viscosity resistance and thus weaken the sedimentation phenomenon, whereas a longer printing time adversely influences part sinking. Optimal thermal conditions that simultaneously ensure low sedimentation and a relatively short printing time should be determined during printing, particularly for thermally thinned materials. Importantly, using the wall-end effect, the model revealed that settlement could be effectively mitigated by solidifying the part near the bottom of the container. The experiments confirmed a reduction of approximately 39.4% in sedimentation displacement. The thermal-solid-fluid coupled model developed in this study offers a valuable tool to guide the design of new photosensitive materials as well as the optimization of process parameters, which is essential to improve the printing outcomes of VAM and thus facilitate its broader applications.
✓ 已验证
DOI
高影响因子
Scientific Reports
·
2026
·
IF 4.9
Li Ruifang,Sun Yan,Feng Mingzhi,Kelsang Drolma,Cai Hanhui,Zhang Jun
Ulcerative colitis (UC) is a chronic disease characterized by intestinal inflammation, mucosal damage, and immune dysregulation. Current treatments are often inadequate, driving the search for alternatives with fewer side effects. Isoliquiritigenin (ISL), a flavonoid from licorice, has demonstrated anti-inflammatory effects, but its efficacy in UC remains uncertain. Male C57BL/6 mice were divided into six groups: Control, DSS model, low-, medium-, and high-dose ISL (25, 50, 100 mg/kg), and 5-aminosalicylic acid (5-ASA, 100 mg/kg). UC was induced by administering 3% DSS, followed by ISL or 5-ASA treatment. Disease activity index (DAI), histopathology, real-time PCR, Western blotting, immunohistochemistry, and 16 S rRNA sequencing were used to assess inflammation, intestinal barrier integrity, and gut microbiota (GM) composition. a Caco-2 cell-based model of UC was developed. After transfection to induce the overexpression of TLR4 and its adaptor protein MyD88, the cells were incubated with ISL. The effects of this intervention were evaluated by measuring the expression of inflammatory cytokines, tight junction-associated proteins, and components of the TLR4/MyD88 signaling pathway. ISL significantly alleviated DSS-induced UC symptoms, such as weight loss and colonic shortening. ISL reduced colonic mucosal damage and inflammatory cell infiltration, downregulated TLR4, MyD88, and phosphorylated NF-κB expression, and lowered TNF-α, IL-1β, and IL-6 levels. It also improved intestinal barrier function by upregulating ZO-1, Claudin-1, and Occludin expression. ISL modulated GM by increasing beneficial bacteria (Muribaculaceae) and reducing pathogenic bacteria (Escherichia-Shigella). Overexpression of TLR4 and MyD88 in the Caco-2 cell line abrogated the protective effects of ISL, as evidenced by increased expression of inflammatory cytokines and downregulated expression of tight junction proteins. Overall, these findings suggest ISL may protects against DSS-induced UC by suppressing the TLR4/MyD88/NF-κB pathway, enhancing intestinal barrier function, and modulating GM, supporting its potential as a therapeutic supplement for UC.
✓ 已验证
DOI
PubMed
高影响因子
Nature Communications
·
2026
·
IF 18.1
Zeng Tao,Fang Jiahui,Hao Jian,Cao Xiuping,Li Shiqing,Bai Shiyan,Chen Jiaying,Li Chunsen,Yang Huanghao,Lu Chunhua
In nature, nuclear DNA complexed with histone form highly condensed chromatin via loop extrusion and microphase separation, yielding physically constrained solid-like structures. Inspired by this natural compaction, here we demonstrate that freezing-induced crystallization pressure and freeze-concentration effects trigger solid-liquid microphase separation for efficient DNA compression. Freezing compress various nucleic acids (single stranded DNA, molecular beacons, siRNA, plasmid DNA) into high-density states that self-assemble into nanoparticles (DNA-NPs, MB-NPs, siBcl-2-NPs, siPLK1-NPs, pEGFP-NPs). Molecular dynamics simulations reveal that ice crystal growth increases solute concentration, enhancing DNA intermolecular interactions to form supramolecular chains. Stress at advancing ice-liquid interfaces further orders and compacts these supramolecular chains into nanoparticles. In breast cancer cells, MB-NPs detect miRNA-21; siBcl-2-NPs downregulate Bcl-2 protein; siPLK1-NPs exhibited antitumor effects; and pEGFP-NPs mediate green fluorescent protein (GFP) expression. This freeze-induced self-assembly strategy replaces chemical synthesis with physical constraints, establishing a versatile platform for facile production of nucleic acid nanoparticles.
✓ 已验证
DOI
高影响因子
Collagen and Leather
·
2026
·Vol. 8
·期 1
·39
·
IF 10.1
Li Can,Zhang Yuanhang,Li Wan,Wang Li,Xiang Jun,Fan Haojun,Jiang Hongmei,Sun Lijuan,Tang Jinsong
Unsaturated vegetable fatty acids, as a renewable resource, are abundantly present in vegetable oils, exhibiting significant potential for the synthesis of bio-polyols and bio-based polyurethanes (PUs). Herein, castor oil (CO) and tea seed oil (TSO) were selected as feedstocks to fabricate bio-based hydrophilic chain extenders (HCEs) for water-based polyurethane (WPU). Firstly, the raw oils were treated through a three-step process involving saponification, acidification and urea inclusion purification, yielding unsaturated ricinoleic acid (RA) and oleic acid (OA) with high purities of 93.99% and 92.72%, respectively. Subsequently, an efficient thiol-ene click reaction was carried out to prepare amphiphilic ricinoleic acid-based chain extender (RACE) and amphiphilic oleic acid-based chain extender (OACE) under ambient conditions (1 h, room temperature) with relatively lower molecular weight ( M w ) and accurate functionality ( f − OH = 2 ). The activation energies for the reactions of RACE/OACE and dimethylolpropionic acid (DMPA) with isophorone diisocyanate (IPDI) were evaluated via non-isothermal DSC kinetic analysis (Kissinger method and Ozawa method), and the apparent activation energy ( Ea from Kissinger/ Eo from Ozawa) values were found to be 76.66/78.88 kJ·mol − ¹ for RACE and 74.58/76.91 kJ·mol − ¹ for OACE, respectively, which were slightly higher than that of DMPA (Ea/Eo = 73.01/75.32 kJ·mol − ¹). Application of these bio-HCEs for preparing WPU revealed that the particle size and absolute zeta potential of emulsion with more than 0.0248 mol bio-HCEs were equivalent to those of the emulsion with 0.0192 mol DMPA, and the resultant WPU films showed enhanced broken elongation, increased water contact angles, and reduced water absorption ratio. Collectively, the significance of this work resides in providing a feasible and potentially universal strategy for fabricating bio-HCEs from natural unsaturated oils and offering a sustainable alternative for the advancement of WPU. Graphical
✓ 已验证
DOI
高影响因子
Food Production Processing and Nutrition
·
2026
·Vol. 8
·期 1
·72
·
IF 6.3
Niu Ruge,Xu Zhongchi,Yang Wenli,Bao Tong,Xu Fengsheng,Zhou Wenqi,Zhang Long,Jia Qi,Wang Xiaolong,Chen Jiandong,Lin Xin
Radiotherapy is a standard treatment for thoracic malignancies, but it frequently leads to radiation‑induced heart disease (RIHD), a serious and dose‑limiting complication for which no targeted therapies are currently available. Total extracts from Abelmoschus manihot (L.) (TEA), known for their cardioprotective properties, are widely used in treating various ischemic heart diseases. Here, we identify ferroptosis driven by the NOX4/SLC7A11/GPX4 axis as a core mechanism of RIHD, with GPX4 serving as the non‑redundant downstream executor. TEA effectively modulates this axis; however, it lacks cardiac selectivity, which may compromise antitumor efficacy. To overcome this barrier, we developed, characterized, and evaluated a novel nanoplatform consisting of TEA‑loaded PLGA nanoparticles conjugated with a primary cardiomyocyte‑specific homing peptide (PCM), further integrated with low-intensity focused ultrasound (LIFU)‑triggered on‑demand release (TEA@PLGA‑PCM). This system achieves superior myocardial accumulation, effectively improves cardiac function, reverses pathological remodeling, and normalizes ferroptosis markers as well as NOX4/SLC7A11/GPX4 protein expression. In summary, we successfully constructed a novel nanoplatform that represents a promising strategy for integrated targeted delivery and synergistic therapy in RIHD management. Graphical
✓ 已验证
DOI
高影响因子
COLLOID AND POLYMER SCIENCE
·
2026
·
IF 2.9
Guo Qi,Zhao Jing,Xiao Ailing,Guo Menglu,Cui Lu,Zheng Li-Na,Liang Fei,Xie Na
Traditional hydrogels are limited by their loose three-dimensional network structure, inadequate mechanical strength, and insufficient synergistic antibacterial and antioxidant activities, which restrict their application as high-performance wound dressings. In this study, a graphene oxide (GO)-reinforced ternary composite hydrogel wound dressing (PVA/CS-GA/GO) based on polyphenol-modified chitosan and polyvinyl alcohol was successfully fabricated via a green repeated freeze–thaw process. The effects of GO incorporation on the microstructure, mechanical properties, antibacterial activity, and antioxidant performance of the composite hydrogels were systematically investigated. The results demonstrated that, at the optimal GO content, the composite hydrogel exhibited a tensile strength of 9.3 kPa and an elongation at break of 2163.7%, representing approximately 1.2-fold and 1.3-fold increases, respectively, compared with the PVA/CS-GA hydrogel. Moreover, GO incorporation further enhanced the antibacterial and antioxidant performances of the hydrogel, achieving a maximum antibacterial rate of 99.8% against Escherichia coli ( E.coli ) and increasing the DPPH radical scavenging activity to 94.8%, corresponding to an approximately 1.9-fold improvement over the PVA/CS-GA hydrogel. In addition, the composite hydrogel exhibited excellent structural stability and biocompatibility, simultaneously achieving mechanical reinforcement and multifunctional performance enhancement. These findings provide a theoretical basis for the design and development of high-performance multifunctional hydrogel wound dressings.
✓ 已验证
DOI
高影响因子
Light-Science & Applications
·
2026
·Vol. 15
·期 1
·376
·
IF 24
Wang Yishuang,Sang Xueqing,Dou Zhen-Long,Zhou Qin-Xing,Zhao Zhiyu,Yang Da-Jie,Zhang Yan,Zhou Li,Li Xiaoguang,Wang Qu-Quan
Plasmon–exciton Fano interference provides an efficient channel for coherent energy transfer, and the plasmon resonance energy transfer (PRET) peak is usually observed around the Fano dip at the exciton resonance. In this work, we achieve tunable multiple Fano interferences and multichannel PRET by strategically coupling five excitonic resonances (labeled as M, D h , D j , H, and J) of assembled IR806 molecules with Au nanobipyramids and nanorods (AuNBPs and AuNRs, respectively). Notably, owing to orientation-dependent molecule–plasmon coupling in the IR806/AuNBP hybrids, we observe two PRET peaks with opposite signs of Fano factor \(q\) . One PRET peak remains fixed near the J-aggregate exciton resonance at ~900 nm, whereas the other is located around the plasmon resonance and tuned from 710 to 920 nm. The total PRET reaches a maximum when the two PRET peaks are tuned into spectral overlap. Furthermore, our newly developed semiclassical model quantitatively reproduces these features, which reveals that PRET enhancement arises from the superposition of multiple Fano interferences. These findings provide a novel strategy to enhance the efficiency and tunability of the PRET, opening avenues for advanced applications in ultrafast optical information processing and highly sensitive photodetectors.
✓ 已验证
DOI
高影响因子
JOURNAL OF MATERIALS SCIENCE
·
2026
·Vol. 61
·期 42
·32799-32819
·
IF 4.4
Yang Lutao,Zhou Chuanchen,Zhang Fang,Yang Jie,He Lei,Zhang Jun
Given the ongoing global demand for oil, polymer–surfactant binary flooding technology plays a key role in enhancing oil recovery. However, in high-temperature, high-salinity, and high-calcium/magnesium reservoirs, traditional binary flooding systems face limitations due to thermal degradation, salt sensitivity, and formation adsorption, significantly reducing their effectiveness. In this study, a novel magnetic nanocomposite, BS@Fe 3 O 4 /MOF, was synthesized using Cu-based metal–organic framework (Cu-MOF)-doped Fe 3 O 4 magnetic nanoparticles and functionalized with dodecyldimethyl betaine (BS-12). The nanocomposite effectively removed Ca 2+ and Mg 2+ ions. Emulsification tests optimized the binary surfactant/polymer (SP) flooding system with octylphenol ethoxylate (OP-10) and xanthan gum (XG) and verified the feasibility of constructing the SP-BS@Fe 3 O 4 /MOF system. The system showed strong tolerance to high temperatures, salinity, and varied pH environments, with a substantial increase in viscosity and ultra-low interfacial tension in crude oil. Adsorption loss was 14%, with separation rates of 8.28% for the nanocomposite and 17.86% for XG. Oil recovery tests showed an 8.22% improvement, and magnetic recovery added another 3.75%. Overall, BS@Fe 3 O 4 /MOF enhances binary flooding, providing a strategic solution for field application challenges.
✓ 已验证
DOI
高影响因子
IONICS
·
2026
·
IF 3.4
Lin Liyang,Shi Benrun,Wang Tingbo,Wang Yan,He Yituan,Wei Zhen
Poly(ethylene oxide) (PEO)-based solid polymer electrolytes (SPEs) are highly attractive for lithium metal batteries, yet their practical viability is fundamentally plagued by sluggish Li + transport, heterogeneous Li deposition, and the severe agglomeration of nanofillers. Herein, we propose a facile “dual-filler synergistic” strategy to architect high-performance SPEs by simultaneously integrating graphene oxide (GO) nanosheets and non-ionic polyvinylpyrrolidone (PVP) into the PEO-LiTFSI matrix. The hydrophobic groups of PVP are anchored onto GO surfaces to construct a polymeric steric layer, synergistically suppressing PEO crystallinity and accelerating lithium salt dissociation. Benefiting from the dual modulation, the GO/PVP-modified PEO electrolyte (GPP SPE) exhibits an ionic conductivity of 4.1 × 10 −4 S cm −1 and a Li + transference number of 0.57 at 60 o C, coupled with a broadened electrochemical stability window of 4.75 V. Consequently, GPP SPE exhibits superior dendrite suppression, enabling symmetric Li||Li cell to cycle stably for over 1000 h at 0.1 mA cm −2 without short-circuiting. Furthermore, the assembled LiFePO 4 ||Li all-solid-state cells exhibit a high initial discharge capacity of 151.1 mAh g −1 at 0.5C and retain 80.44% capacity after 200 cycles. This study elucidates a scalable and robust paradigm for designing high-safety, high-performance solid-state electrolytes for next-generation energy storage.
✓ 已验证
DOI
高影响因子
Nature Communications
·
2026
·
IF 18.1
Li Jia-Yang,Guo Ying,Wang Xin,Pang Wei Kong,Hu Hai-Yan,Zhu Yan-Fang,Chen Diancheng,Liu Xin-Yu,Gu Qin-Fen,Johannessen Bernt,Zheng Xiaobo,Sun Yang,Cheng Shaobo,Yuan Yifei,Wu Chao,Wang Jia-Zhao,Dou Shi-Xue,Xiao Yao
Layered oxide cathodes have attracted worldwide attention due to environmentally friendliness, structural diversity, and economic benefits. However, poor long-term cycling and unsatisfactory rate performance hinder the practical application. Hence, an oxide cathode with self-adaptive volume has been designed, achieving stable capacity retention of 82% after 1000 cycles at 2 C. The enhanced long-term performance is attributed to its dynamically adjustable volume reducing the acceleration of stress, enabled by a tunable interlayer distance that expands at the beginning of the charging process and then compresses at the highest voltage. Uniform electric field distribution is depicted by 4-dimensional scanning transmission electron microscopy showing even Coulombic interactions between the oxide layers leading to high mechanical integrity. Such self-adaptable behavior originates from the reduced repulsive force between interlayered oxygen due to the charge reconfiguration of intralayer oxygen and transition metal ions. Additionally, the charge compensation behavior is detected by in situ X-ray absorption spectra, which would be beneficial to high-rate performance. The self-adaptive volume change driven by charge reconfiguration provides a pathway toward durable materials for sustainable sodium-ion energy storage.
✓ 已验证
DOI
高影响因子
危险品化学品经营许可证（带存储）