CHINESE JOURNAL OF POLYMER SCIENCE
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2024
·
IF 4.1
Xiao Le-Ping,Qiu Lv-Ming,Wu Zhen,Wang Guo-Jie
To realize single-stimulus-induced simultaneous multi-behaviors in hydrogels is still quite challenging nowadays. Herein, an intelligent pH-responsive hydrogel (BP4VA/PAS) with rapid and high contrast changes in color, fluorescence, and shape simultaneously is reported. The BP4VA/PAS hydrogel is fabricated by incorporating styryl anthracene derivative (BP4VA) into copolymer networks (PAS) of acrylamide and sodium 4-styrene sulfonate. Under acid conditions, the protonation of BP4VA generates a rapid change with high color contrast from yellow to red and a fluorescence switch between bright green and weak red emission. At the same time, the electrostatic interactions between 2H-BP4VA 2+ and sulfonate anions suspended on PAS trigger BP4VA/PAS hydrogels to shrink. Upon alkaline treatment, the 2H-BP4VA 2+ /PAS hydrogel deprotonates and recovers to its original color, fluorescence, and shape. Furthermore, utilizing rapid and remarkable pH-responsive properties of BP4VA/PAS hydrogels, we successfully demonstrated its applications in biomimicry, camouflage, and multistage information encryption. Collectively, this work provided an elegant strategy to develop intelligent hydrogels in applications of biomimetic smart materials and information encryption.
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SEPARATION AND PURIFICATION TECHNOLOGY
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2024
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IF 8.1
Shuang Wu,Yangli Cui,Lan Liang,Wenjie Gao,Zhen Yu,Zhanjun Cheng,Beibei Yan,Guanyi Chen,Ning Li
Heterogeneous catalyst reuse and the effectiveness of hydrogen peroxide (H 2 O 2 )-based advanced oxidation processes under near-neutral conditions remain an obstacle in wastewater remediation. Herein, we put forward a versatile catalytic membrane with Cu-doped MnO active layer anchoring on the polydopamine-modified electrospinning polyvinylidene fluoride (PDA@PVDF) base. The Cu-MnO@PDA@PVDF membrane was conferred admirable sulfamethoxazole (SMX) reduction (over 90% within 90 min) and clogging alleviation (relative flux recovery to 0.98) capabilities via in situ H 2 O 2 activation at pH 8, which was slightly affected by actual water background. Electron paramagnetic resonance (EPR) and trapping tests unveiled the joint contribution of • OH, O 2 •− and 1 O 2 , with • OH exerting the supreme role in SMX oxidation. The inherent characteristics of dual Mn-Cu centers on the membrane surface for facilitation of electron transfer, H 2 O 2 adsorption and barrierless dissociation to • OH were further elucidated by electrochemical measurements and density functional theory (DFT) computation. Comprehensively, this study proposes a facile procedure and insights into engineering catalytic membrane coupled H 2 O 2 strategy for refractory organic treatment at ambient conditions.
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JOURNAL OF SOLID STATE CHEMISTRY
·
2024
·
IF 3.2
Yuning Wang,Yang Chen,Yongjian Xu,Yatao Yan,Ming Chen,Mengting Shao,Qianhui Wu,Fang Guo,Jianhua Hou
The development of cheap, efficient and stable hydrogen-producing catalysts is the current research focus, especially the catalysts that can work stably in the whole pH range. In this work, a myrica rubra-like structure of P–Co 1-x S/C was synthesized by hydrothermal reaction, sulfurization and phosphorization using spherical flower-like cobalt glycerate (CoG) as precursor. The design of this multilevel structure of P–Co 1-x S/C effectively increases the specific surface area. The doping phosphorus and the protection of carbon layer greatly improve catalytic performance and enhance the stability of Co 1-x S in the hydrogen evolution reaction (HER) at full pH range. When the current density is 10 mA cm −2 , the HER overpotentials of P–Co 1-x S/C in acidic, alkaline and neutral solutions are 86, 93 and 167 mV, and respectively. The Tafel slopes of P–Co 1-x S/C in acidic, alkaline and neutral solutions are 82, 100 and 103 mV dec −1 , respectively. In addition, the electrocatalyst also displays excellent electrochemical long-term stability. After 2000 cycles or 20 h long-term testing, its catalytic activity remains stable without obvious decrease at full pH range.
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Future Microbiology
·
2025
·
IF 2.4
Ao Du,Xiaofen Sun,Meili Dong,Yong Liu,Mingwei Chen,Yuhan Wang,Yuanzhi Zhang,Yao Huang,Zhongsheng Li,Xiang Huang,Yikun Wang,Jingshu Ni
Aims This study aims to investigate how different wound microenvironmental factors (temperature, pH, and osmotic pressure) influence the autofluorescence of Staphylococcus aureus (S. aureus) and its underlying molecular mechanisms, specifically focusing on the porphobilinogen synthase gene (hemB) gene expression.Methods We measured the average fluorescence intensity of S. aureus colonies under varying conditions of pH (3, 5, 7, 9, 11), temperature (25°C, 31°C, 37°C, 43°C), and osmotic pressure (0.9%, 1.8%, 2.7%, 3.6%) over time. Fluorescence intensity was quantified using ImageJ software. Additionally, RT-qPCR was used to analyze the expression levels of the hemB under these conditions.Results Bacterial fluorescence intensity increased as the temperature ranged from 25°C to 43°C, with corresponding upregulation of hemB expression. At pH values between 3 and 11, fluorescence intensity decreased as pH increased, reflecting a similar trend in hemB expression. Fluorescence also diminished with higher osmotic pressures (0.9% to 3.6%), mirroring the downregulation of hemB.Conclusions Our findings indicate that temperature, pH, and osmotic pressure significantly affect the autofluorescence of S. aureus by modulating porphyrin accumulation through hemB gene expression. These environmental factors should be considered when using bacterial fluorescence for wound infection assessment.
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INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2025
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IF 8.5
Qile Chen,Tong Ye,Shujuan Yang,Linwang Fan,Chaonan Shang,Yuhong Feng,Jiacheng Li,Yujuan Wang,Gaobo Yu,Jun Dai
The effective management of Type 2 Diabetes Mellitus (T2DM) depends on the development of streamlined, sustainable, and intelligent delivery systems. In this context, targeted stimulus-responsive Pickering emulsions (PEs) derived from biomass have emerged as a promising candidate. However, the interfacial films of PEs exhibit insufficient strength to endure the harsh gastric environment and lack the capability for targeted and responsive delivery. To address these limitations, an amphiphilic phenylboronic acid-functionalized sodium alginate (SA-PBA) was integrated into a ternary complex platform composed of soybean protein-isolated polyphenol (SPI-PSPAs), where it self-assembled into soft colloidal particles through multiple non-covalent interactions. A multiscale coupling methodology was proposed to investigate and elucidate the structure-function relationship between interfacial characteristics (e.g., thickness, viscoelasticity, and microstructures) and the stability of PEs, thereby providing a foundation for effectively controlling their targeted delivery properties. Notably, owing to the enhanced strength of the interfacial composite particle films, the PEs demonstrated the ability to withstand the harsh gastric environment while maintaining their structural integrity. Furthermore, the self-assembly process of the soft SA-PBA@SPI-PSPAs colloids could be modulated by external glucose stimuli, enabling the targeted and intelligent release of PSPAs in the intestinal environment. Consequently, the well-designed PE system achieved intestinal-targeted responsive release effects, highlighting the potential of the natural α-glucosidase (αG) inhibitor PSPAs as a viable clinical treatment for T2DM.
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APPLIED PHYSICS A-MATERIALS SCIENCE & PROCESSING
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2017
·Vol. 124
·期 1
·1-9
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IF 1.455
Zhao Linyan,Li Lian,Wang Yixi,Wu Jianning,Meng Guihua,Liu Zhiyong,Guo Xuhong
Oily wastewater caused by industrial production and crude oil leakage has attracted worldwide attention. Here, a thermo- and pH dual-responsive biodegradable cellulose-based aerogel for oil–water separation was designed and prepared via surface-initiated atom transfer radical polymerization (ATRP) of non-fluorine-containing 2-dimethylaminoethyl methacrylate (DMAEMA). The cellulose-based aerogel exhibit switchable superhydrophilicity with a water contact angle (WCA) of 0° and hydrophobicity (WCA 130°) by modulating pH or temperature. The functionalized cellulose-based aerogels could be used to absorb the water under 60 °C (pH 7.0) and pH is 1.0 (T = 25 °C), while absorb oil underwater when the temperature is above 60 °C (pH 7.0) or pH is 13.0 (T = 25 °C). So this adsorbent were suitable for the separation of water-rich or oil-rich oil/water mixtures, and it could adsorb oil over ten times its own weight, and had a good reusability. What’s more, the cellulose-based aerogel is green, low cost, and environmental friendly, which makes it a promising candidate to be used for oil–water separation.
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ELECTROCHIMICA ACTA
·
2018
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IF 5.116
Kelong Ao,Dawei Li,Yixin Yao,Pengfei Lv,Yibing Cai,Qufu Wei
Heteroatom doping is a feasible approach to adjust catalytic performance of the HER catalysts. In this work, we report a design of Fe-doped Co 9 S 8 nanosheets grown on carbon cloth (Fe-Co 9 S 8 NSs/CC) as a hydrophilic 3D monolithic electrocatalyst for efficient hydrogen evolution under all pH. The water contact angle and electrochemical measurements proved that the resultant material was hydrophilic for its nano hierarchitectures and dopant Fe enhanced the catalytic capability of singular Co 9 S 8 . In 1.0 M KOH, the Fe-Co 9 S 8 NSs/CC possessed a relatively small Tafel slope (95.3 mV dec −1 ) and required the overpotential of 83 mV to achieve 10 mA cm −2 . To drive the same current density, the overpotentials were 65 and 192 mV in 0.5 M H 2 SO 4 and 1.0 M PBS, respectively. Meanwhile, it showed good cycle stability and durability over 20 h static test at alkaline and neutral condition. The flexible freestanding catalyst has great potential in practical applications.
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JOURNAL OF NANOPARTICLE RESEARCH
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2017
·Vol. 19
·期 12
·1-11
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IF 2.02
Chen Daquan,Song Xiaoyan,Wang Kaili,Guo Chunjing,Yu Yueming,Fan Huaying,Zhao Feng
In this article, in order to enhance the bioavailiability and tumor targeting of curcumin (Cur), the oligosaccharides of hyaluronan conjugates, folic acid-oligosaccharides of hyaluronan-acetal-menthone 1,2-glycerol ketal (FA-oHA-Ace-MGK) carried oHA as a ligand to CD44 receptor, double-pH-sensitive Ace-MGK as hydrophobic moieties, and FA as the target of folate receptor. The structure characteristics of this smart response multifunctional dual-targeting nano-sized carrier was measured by fourier-transform infrared (FT-IR) and nuclear magnetic resonance ( 1 H–NMR). Cur, an anticancer drug, was successfully loaded in FA-oHA-Ace-MGK micelles by self-assembly. The measurement results of transmission electron microscopy (TEM) presented that the Cur-loaded micelles were spherical in shape with the average size of 166.3 ± 2.12 nm and zeta potential − 30.07 mV. Much more encapsulated Cur could be released at mildly acidic environments than at pH 7.4, from the Cur-FA-oHA-Ace-MGK micelles. Cytotoxicity assay indicated that non-Cur loaded micelles mostly had no cytotoxicity to MCF-7 cells and A549 cells, and Cur-loaded micelles had significantly lower survival rate than Cur suspension in the same concentration, which proved that the drug-loaded micelles can effectively inhibit tumor cell growth. The targeting of CD44 receptors and folate receptors was proved in vitro cellular uptake assay. These results showed the promising potential of FA-oHA-Ace-MGK as an effective nano-sized carrier for anti-tumor drug delivery.
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JOURNAL OF COLLOID AND INTERFACE SCIENCE
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2018
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IF 5.091
Jin Liu,Wei Lu,Qian Zhong,Hongzhang Wu,Yunlin Li,Lili Li,Zhenling Wang
Semiconductor photocatalysis has become the focus of recent research on antibiotic treatment because it is a green and efficient technology. In this study, α-GaOOH with several novel microstructures has been synthesized at a low temperature and its subsequent thermal transformation. The influence of pH on the synthesis of α-GaOOH is studied, and the results indicate that pH played an important role in the microstructures of α-GaOOH and β-Ga 2 O 3 . All Ga 2 O 3 samples possess macro-mesoporous network structures and exhibits a remarkable photocatalytic activity for antibiotic degradation. The photoelectron chemical tests show that the separation efficiency of photogenerated charge carriers of Ga 2 O 3 -7.0 is higher than that of other Ga 2 O 3 . The enhanced photocatalytic activity of Ga 2 O 3 -7.0 is mainly ascribed to its morphology and oxygen vacancy . The active species trapping and photoluminescence measurement experiments indicate that OH and O 2 − are the major active species contributing to the photocatalytic process. This study will bring about the potential application in treatment of the antibiotic pollutants.
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JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY
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2018
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IF 2.297
Hailiang Feng,Yu Sun,Jianhua Zhang,Liandong Deng,Anjie Dong
Undesired physiological instability remains a major limitation for nanoparticle-based drug delivery. To overcome this issue, a dual pH-responsive supramolecular layer-crosslinked nanoparticles (PCB- b -PCD/PBM- b -PDPA NPs, PDM NPs), which consisted of pH-responsive hydrophobic poly(diisopropylethyl methacrylate) (pKa ≈6.3) as the core, hydrophilic poly((methacrylic acid betaine) methyl methacrylate) as the shell and pH-responsive supramolecular crosslinked layer based on β-cyclodextrin and benzimidazole (pKa <6.0), was prepared. Effects of this supramolecular layer-crosslinked structure on dilution and stored stability, protein adsorption, and pH-responsibility were investigated. PDM NPs exhibited lower critical aggregation concentrations, good unimodal distribution and better dilution stability in comparison with non-crosslinked PCB-PDPA NPs. Moreover this pH-responsive supramolecular layer-crosslinked structure did not only influence the anti-protein adsorption ability, but also reduced the disintegrated pH (from 6.3 to below 6.0) of PDM NPs, which leads to the DOX was released from PDM NPs at the mildly acid condition effectively and sustainably in vitro . Therefore, this pH-responsive layer-crosslinked NPs held promising potentials as a smart nanocarriers for drug delivery.
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RSC Advances
·
2018
·Vol. 8
·期 17
·9334-9343
·
IF 2.936
Hailong Huang,Lifeng Hou,Feng Zhu,Juan Li,Min Xu
A series of controllable thermal and pH dual-responsive copolymeric hydrogels (PMA) were prepared by a one-pot reaction with poly(ethylene glycol) methyl ether acrylate (PEGA), 2-methoxyethyl acrylate (MEA) and acroleic acid (AA). The hydrogels exhibited good mechanical properties and a sensitive response to pH and temperature. Besides, the Lower Critical Solution Temperature (LCST) of the hydrogels can be adjusted from 37 °C to 58 °C by changing the content of AA. The hydrogels also showed excellent selective adsorption properties. The maximum adsorption quantity of organic cationic dye brilliant green and methylene blue were 0.49 mg mg−1 and 0.42 mg mg−1 respectively, much better than previous reports. Furthermore, using the thermal and pH responsibility, the PMA hydrogels can release the adsorbed molecules with control. Nearly 95% of carriers could be released at pH 4.01 and 65 °C over 8 h. The regeneration ability makes the materials easy to reuse many times. Due to these properties, these dual-responsive hydrogels have great potential applications in various fields for adsorption, drug delivery, release and tissue engineering.
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ACS Applied Materials & Interfaces
·
2024
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IF 8.3
Peng-Cheng Guan,Qian-Jiao Qi,Yu-Qing Wang,Jia-Sheng Lin,Yue-Jiao Zhang,Jian-Feng Li
Traditional diagnostic methods, such as blood tests, are invasive and time-consuming, while sweat biomarkers offer a rapid physiological assessment. Surface-enhanced Raman spectroscopy (SERS) has garnered significant attention in sweat analysis because of its high sensitivity, label-free nature, and nondestructive properties. However, challenges related to substrate reproducibility and interference from the biological matrix persist with SERS. This study developed a novel ratio-based 3D hydrogel SERS chip, providing a noninvasive solution for real-time monitoring of pH and glucose levels in sweat. Encapsulating the probe molecule (4-MBN) in nanoscale gaps to form gold nanoflower-like nanotags with internal standards and integrating them into an agarose hydrogel to create a 3D flexible SERS substrate significantly enhances the reproducibility and stability of sweat analysis. Gap-Au nanopetals modified with probe molecules are uniformly dispersed throughout the porous hydrogel structure, facilitating the effective detection of the pH and glucose in sweat. The 3D hydrogel SERS chip demonstrates a strong linear relationship in pH and glucose detection, with a pH response range of 5.5–8.0 and a glucose detection range of 0.01–5 mM, with R2 values of 0.9973 and 0.9923, respectively. In actual sweat samples, the maximum error in pH detection accuracy is only 1.13%, with a lower glucose detection limit of 0.25 mM. This study suggests that the ratio-based 3D hydrogel SERS chip provides convenient, reliable, and rapid detection capabilities with substantial application potential for analyzing body fluid pH and glucose.
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