MICROCHIMICA ACTA
·
2024
·Vol. 191
·期 5
·1-9
·
IF 5.3
Li Yunpeng,Shi Zhuanzhuan,Wu Xiaoshuai,Miao Wenting,Yang Zhengyi,Lou Xinyu,Sun Wei,Guo Chunxian,Li Chang Ming
PEDOT:PSS has been used as a biomimetic uric acid (UA) sensor but suffers from unfortunate low detection limit (LOD), narrow detection range and poor stability. Herein, we get graphdiyne (GDY) marry PEDOT:PSS to create a very stable GDY@PEDOT:PSS heterostructure for a biomimetic UA sensor, which accomplishes the lowest LOD (6 nM), the widest detection range (0.03 μM-7 mM) and the longest stability (98.1% for 35 days) among the related UA sensors. The sensor was successfully used to in situ real-time detection of UA in sweat. The enhancement mechanisms of the sensor were investigated, and results discover that C≡C of GDY and C = C of PEDOT:PSS can cross-link each other by π–π interactions, making not only the former strongly resistant against oxidation deterioration, but also causes the latter to efficiently prevent water swelling of polymer for poor conductivity, thereby leading to high stability from both components. While the stabilized heterostructure can also offer more active sites by enhanced absorption of UA via π-π interactions for highly sensitive detection of UA. This work holds great promise for a practical sweat UA sensor while providing scientific insight to design a stable and electrocatalytically active structure from two unstable components. Graphical abstract
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高影响因子
Nano Research
·
2024
·Vol. 17
·期 6
·5595-5603
·
IF 9.5
Zhou Runhui,Huang Jiaoya,Li Zemin,Wang Yushu,Chen Ziyu,Pan Caofeng
Stretchable hybrid systems have been attracting tremendous attention for their essential role in soft robotics, on-skin electronics, and implantable devices. Both rigid and soft functional modules are typically required in those devices. Consequently, ensuring stable electrical contact between rigid and soft modules is a vital part. Here, we propose a simple, universal, and scalable strategy for the stretchable hybrid system through a highly precise printable liquid metal particle-based conductor and adhesive fluorine rubber substrate. The properties of liquid metal particle-based conductors could be easily tuned to realize high-precision patterning, large-scale printing, and the ability to print on various substrates. Additionally, the fluorine rubber substrate could form strong interfacial adhesion with various components and materials through simply pressing and heating, hence enabling stable electrical contact. Furthermore, we prepared a stretchable hybrid light-emitting diode (LED) display system and employed it in on-skin visualization of pressure levels, which perfectly combined rigid and soft modules, thus demonstrating the promising potential applications in complex multifunctional stretchable hybrid systems for emerging technologies.
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JOURNAL OF FLUORESCENCE
·
2024
·
IF 2.6
Zuo Pengli,Peng Jun,Yao Yuyang,Tan Wei,Cheng Lan,Zhang Jinyu,Lu Xiuhua
Due to the unique chemical and biomedical properties of carbon dots (CDs), they have increasingly obtained the attention in many research fields, for example, bioimaging, fluorescence sensing, and drug delivery, etc. Recently, it was found that, under light excitation, CDs can also be exploited as a novel photosensitizer to prepare reactive oxygen species (ROS), which expand their applications in the field of photodynamic therapy for cancer treatment. Nevertheless, the high cost and complex fabrication approach of CDs significantly limit their applications. To address this issue, bottom-up routes usually utilize sustainable and inexpensive carbon precursor as starting materials, employed N,N-dimethylformamide (DMF) or ethanol as an environmental-friendly solvent. Bottom-up approach was energy efficient, and the purification process was relatively simple by dialysis. Therefore, carbon dots (CDs) were facilely fabricated in a one-pot solvothermal process using 1-aminoanthraquinone as a precursor, and their application as photosensitizers for in vitro antitumor cells, especially photodynamic therapy (PDT) was established. Then the photophysical and nanoscale dimensions properties of the fabricated CDs were characterized via TEM, UV–visible, fluorescence, and FT-IR spectroscopy. The synthesized N-doped CDs can easily dissolve in water, possess very low biotoxicity, yellow-light emission (maximum peak at 587 nm). More importantly, PDT studies demonstrated that the obtained CDs possess a high singlet oxygen yield of 35%, and exhibit significant phototoxicity to cancer cells upon 635 nm laser irradiation. These studies highlight that N-doped CDs can be facilely synthesized from only one precursor, and are a potentially novel theranostic agent for in vivo PDT.
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JOURNAL OF POLYMER RESEARCH
·
2024
·Vol. 31
·期 5
·1-12
·
IF 2.6
Xing Jinfu,Gu Jun,Liu Bujin,He Li,Jiang Tuanhui
The type and structure of nucleating agents have an important influence on the properties of the final foam as well as on the nucleation of the bubbles during injection foaming. In this study, a simple melt blending method was used to prepare polypropylene/nucleating agents (PP/NAs) composites containing nucleating agents with different structures, and the rheological behavior of the PP/NAs composites was studied using a rotational rheometer. According to the rheological data, the structure of the nucleating agent was not the primary reason for influencing polymer viscosity. Additionally, PP/NAs composite foams were prepared by chemical foaming injection molding process and the bubble dynamics, cell quality and tensile properties were investigated. The results exhibited that polymers with β-cyclodextrin (β-CD), which had a self-contained cavity-circular table structure, as the nucleating agent have better bubble nucleation dynamics. The tensile toughness of PP/β-CD foam was increased from 8.21 MJ/cm 3 to 20.54 MJ/cm 3 , an improvement of 150.34% by comparison with pure PP foam, which was attributed to having an average cell diameter of 23.98 μm and a cell density of 2.36 × 10 7 cells/cm 3 . Therefore, this study provides a reference for the design of efficient nucleating agents for the preparation of structural foam materials with lightweight and tough properties.
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CELLULOSE
·
2024
·Vol. 31
·期 14
·9025-9042
·
IF 4.9
Li Wenjian,Luo Fubin,Dai Yumei,Chen Delong,Li Hongzhou
Ramie fibers have poor flame-retardant properties, which limits their application. To improve the flame-retardant properties of ramie fabric (RF), a durable flame-retardant coating was successfully realized on RF by combining covalent bonding and electrostatic adsorption. Si/P/N flame-retardant coatings were constructed on RF using cationic polyethyleneimine (PEI) and anionic sodium hexametaphosphate (PSP) via the layer-by-layer (LBL) assembly approach with the introduction of 3-glycidoxypropyltrimethoxysilane (GPTMS) as an organic cross-linker. Compared with the untreated RF samples, the fabrics treated with the flame-retardant coating PEI/PSP via the LBL method presented reductions of 51.06%, 48.30%, and 40.05% in the fire growth rate, peak heat release rate, and total heat release, respectively, in the cone calorimeter test. In addition, at a weight gain of 31.57%, the fabric self-extinguished in the UL-94 test within 10 s after leaving the ignition source, resulting in a damaged length of 6.13 cm. G-3 retained the limiting oxygen index (LOI) of 26.40% after 6 laundering cycles (LCs). The TG results revealed that the char residue of G-3 at 800 °C reached 30.34 wt%. The surface of the flame-retardant coating of GPTMS-PEI/PSP had good char formation. This study provides a feasible method for realizing durable flame-retardant RFs.
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IONICS
·
2024
·Vol. 30
·期 7
·4281-4295
·
IF 2.4
Li Lanchen,Peng Xuesong,Jiang Jie,Li Ruopeng,Zhang Jinqiu,Yang Peixia,An Maozhong
With the global proliferation of 5G technology, advancing electronic interconnection technologies has become critically important. The development of high-quality electrolytic copper foils, essential for efficient signal transmission, has garnered considerable attention. To mitigate the "skin effect" that could impair signal transmission and to ensure robust adhesion of electrolytic copper foils to the substrate, it's necessary to roughen the copper foils. This roughening process aims to substantially enhance the peel strength of the copper foils without exceeding the bounds of acceptable roughness. An effective strategy to achieve this involves the use of additives to refine the micro-coarsened surface of the copper foils. In this context, we have explored the impact of additives such as carrageenan, guar gum, and SPS on the surface morphology, roughness, and peel strength of electrolytic copper foils. Three types of additives can improve the performance of micro-roughened copper foil. Through electrochemical tests, it was found that all three types of additives have the effect of increasing cathodic polarization. The adsorption behavior of different additives was studied through theoretical calculations. By hybriding the three additives, two micro-coarsening systems were screened to obtain the lowest roughness and the highest peel strength, respectively. At the same time, the relationship between peel strength and surface area was verified, with the larger surface area resulting in greater peel strength. Finally, the synergistic effect of the three additives on increasing cathodic polarization was verified through chronopotentiometry. Graphical Abstract
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Journal of Food Measurement and Characterization
·
2024
·Vol. 18
·期 5
·3868-3880
·
IF 2.9
Mayire Abulitifu,Wei Qin,Wang Yingbo,Bai Xi
The citronellol-rich Origanum vulgare essential oil (OEO), which exhibits excellent antioxidant and antimicrobial activities, has limited use in food packaging owing to its high volatility and instability. This problem can be solved using electrospinning. In this study, OEO was incorporated into the zein matrix via emulsion electrospinning. OEO was obtained by hydro-distillation; gas chromatography–mass spectrometry analysis revealed that citronellol (44.34%) was a predominant compound in OEO. Scanning electron microscopy images demonstrated that the fibers had a bead-free and uniform structure with a diameter ranging from 215 ± 36 to 260 ± 72 nm. The X-ray diffractograms indicate the amorphous structure of the zein fibers. Fourier transform infrared absorption spectroscopy revealed an interaction between OEO and zein. The addition of OEO to the zein nanofibers affected its secondary structure. Thermogravimetric analysis showed that the OEO-loaded (OEO/zein) nanofibers exhibited high thermostability and that the water contact angle was enhanced. The encapsulation efficiency and loading capacity were in the range of 71.56–85.8% and 8.88–40.93%, respectively. The antioxidant activity of the OEO/zein nanofibers ranged from 45.40% to 71.50%. The OEO/zein fibers displayed antimicrobial activity against Staphylococcus aureus and Escherichia coli . In conclusion, OEO/zein nanofibers are promising alternatives for active food packaging.
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ARCHIVES OF TOXICOLOGY
·
2025
·
IF 6.9
Su Ziyang,Kong Rui,Huang Chengqing,Wang Kun,Liu Chenhao,Gu Xiaozhen,Wang Hui-Li
Microplastics exposure can induce brain dysfunction like cognitive impairment, Parkinson's disease, and autism spectrum disorders. In this study, we aimed to investigate the effects of Polystyrene nanoplastics (NPS) on anxiety and depression in mice. First, Polystyrene nanoplastics (NPS) (10 mg/kg) were administered orally daily for two months starting at PND 21. Subsequently, behavioral tests about anxiety and depression were conducted, including the open field test, the elevated plus maze, the forced swimming test, and the tail suspension test. The results showed that NPS induced anxiety and depression-like behaviors in mice. The mPFC played a pivotal role in the etiology of anxiety and depression, in which nanoplastics led to impaired synaptic transmission and reduced neuronal activity in vivo in mPFC. Furthermore, the astrocyte marker GFAP was abnormally increased as observed in mPFC. The abnormal activation of astrocytes results in impaired glutamate recycling through decreasing the expression of the glutamate transporter protein EAAT2 after NPS exposure. In order to ascertain the function of EAAT2, the EAAT2 activator (LDN-212320) was employed to stimulate the expression of EAAT2. Following the activation of EAAT2, synaptic transmission, and anxiety and depressive behavior were rescued in the mice. Polystyrene nanoplastics induce anxiety and depressive-like behavior in mice possibly inhibiting astrocyte EAAT2 expression. Specific activation EAAT2 of astrocytes rescue anxiety and depressive behavior in nanoplastics exposed mice.
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Communications Biology
·
2024
·Vol. 7
·期 1
·1-13
·
IF 5.2
Lin Hui,Lin Shuaijun,Shi Liuhong,Xu Guangsen,Lin Manjie,Li Supeng,Chen Jiale,Li Zhiquan,Nakazibwe Catherine,Xiao Yunbei,Li Xiaokun,Pan Xuebo,Wang Cong
The acquisition of ectopic fibroblast growth factor receptor 1 (FGFR1) expression is well documented in prostate cancer (PCa) progression, notably in conferring tumor growth advantage and facilitating metastasis. However, how FGFR1 contributes to PCa progression is not fully revealed. Here we report that ectopic FGFR1 in PCa cells promotes transferrin receptor 1 (TFR1) expression and expands the labile iron pool (LIP), and vice versa. We further demonstrate that FGFR1 stabilizes iron regulatory proteins 2 (IRP2) and therefore, upregulates TFR1 via promoting IRP2 binding to the IRE of TFR1. Deletion of FGFR1 in DU145 cells decreases the LIP, which potentiates the anticancer efficacy of iron chelator. Intriguingly, forced expression of IRP2 in FGFR1 depleted cells reinstates TFR1 expression and LIP, subsequently restoring the tumorigenicity of the cells. Together, our results here unravel a new mechanism by which FGFR1 drives PCa progression and suggest a potential novel target for PCa therapy.
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JOURNAL OF NANOBIOTECHNOLOGY
·
2024
·Vol. 22
·期 1
·1-16
·
IF 10.6
Zhao Yulan,Wu Yang,Xu Quan,Liu Yi,Song Zhiyong,Han Heyou
Reactive oxygen species (ROS) has emerged as potent therapeutic agents for biofilm-associated bacterial infections. Chemodynamic therapy (CDT), involving the generation of high-energy ROS, displays great potential in the therapy of bacterial infections. However, challenges such as insufficient hydrogen peroxide (H 2 O 2 ) and over-expressed glutathione (GSH) levels within the microenvironment of bacterial biofilms severely limit the antibacterial efficacy of CDT. Herein, we have developed a multifunctional nanoplatform (CuS@CaO 2 @Dex) by integrating copper sulfide (CuS) and calcium peroxide (CaO 2 ) into dextran (Dex)-coated nanoparticles. This innovative platform enhanced ROS generation for highly efficient biofilm elimination by simultaneously supplying H 2 O 2 and depleting GSH. The Dex-coating facilitated the penetrability of CuS@CaO 2 @Dex into biofilms, while CaO 2 generated a substantial amount of H 2 O 2 in the acidic biofilm microenvironment. CuS, through a Fenton-like reaction, catalyzed the conversion of self-supplied H 2 O 2 into hydroxyl radicals (•OH) and consumed the overexpressed GSH. Additionally, the incorporation of near-infrared II (NIR II) laser irradiation enhanced the photothermal properties of CuS, improving the catalytic efficiency of the Fenton-like reaction for enhanced antibacterial effects. In vivo experiments have demonstrated that CuS@CaO 2 @Dex exhibited remarkable antibacterial and antibiofilm efficacy, exceptional wound healing capabilities, and notable biosafety. In summary, the Dex-coated nanoplatform proposed in this study, with its self-sterilization capability through ROS, holds significant potential for future biomedical applications.
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Journal of Applied Spectroscopy
·
2024
·Vol. 91
·期 4
·903-911
·
IF 0.8
Zheng Zhiheng,Zhang Fan,Liu Yankun,Wang Zhiwu,Pei Yuan,Wu Zhengang,Li Bo,Wei Yingna,Chen Ying,Wei Hengyong,Li Jingwu
TiN–Ag@Ag composite substrates were prepared via ammonia reduction nitridation followed by electrochemical deposition. Fabricated TiN–Ag@Ag substrates were characterized using X-ray diffraction, X-ray photoelectron spectroscopy, scanning electron microscopy, transmission electron microscopy, and ultraviolet-visible spectrophotometry. The surface-enhanced Raman spectroscopy activity of these substrates was evaluated using ibuprofen as the probe molecule. The size of the Ag particles prepared via electrochemical deposition was approximately 1 μm, and Ag nanoparticles with an average particle size of 100 nm were uniformly distributed on the surface of TiN–Ag films. The Raman signal of ibuprofen was significantly enhanced, and the minimum detection concentration of ibuprofen was 10 –5 M. The mechanism by which the TiN–Ag@Ag composite substrate enhanced the Raman signals was analyzed using ultraviolet photoelectron spectroscopy and density functional theory implemented in the Gaussian software. Overall, charge transfer and the local electromagnetic field effect enhanced the Raman signals of ibuprofen.
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RARE METALS
·
2025
·
IF 11
Zhao Zhi-Hua,Ma Shi-Xin,Pan Ya-Fang,Rahmatullah Abu-Bakker-Md,Shen Xiao-Qing,Shao Zhi-Gang,Wu Lan
To facilitate real-time monitoring and recording of humidity in the environment and to satisfy the requirement for strain performance in certain applications (such as wearable devices), this paper proposes an in-situ method for synthesising Au nanoparticles on ZIF-67. In this study, an Au@ZIF-67 composite humidity-sensitive material was combined with flexible polyethylene terephthalate interdigitated electrodes to create an Au@ZIF-67 flexible humidity sensor. The prepared samples were characterised using X-ray diffraction, X-ray photoelectron spectroscopy, and transmission electron microscopy. The humidity-sensitive properties of the sensor were investigated, and its monitoring capabilities in applications involving respiration, gestures, skin, and baby diapers were tested. The experimental results indicate that compared with a pure ZIF-67 humidity sensor, the Au@ZIF-67 (0.1Au@Z) flexible humidity sensor exhibits a 158.07% decrease in baseline resistance and a 51.66% increase in sensitivity to 95% relative humidity, and the hysteresis, response time, and recovery time are significantly reduced. Furthermore, the sensor exhibits excellent characteristics such as high resolution, repeatability, and stability. The obtained results regarding the material properties, humidity sensitivity, and practical application of non-contact humidity monitoring demonstrate that the prepared sensors exhibit excellent and comprehensive performance, indicating their broad prospects in wearable medical devices, wireless Internet of Things, humidity detection in complex environments, and intelligent integrated systems. Graphical abstract
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危险品化学品经营许可证（带存储）