Advanced Optical Materials
·
2026
·
IF 7.2
Xuetao Yan,Lifei Chen,Yuze Ren,Kaixuan Cui,Tianliang Li,Lixing Lin,Zeyu Li,Haicheng Song,Yingying Chen,Zhenzhen Li,Lingyan Feng
Circularly polarized luminescence (CPL) materials are highly sought after for their unique chiroptical properties, but their rational design remains challenging. To address this, a machine learning (ML) platform that intelligently screens deep eutectic solvents (DES) for crafting G-quartet-based gels with tailored CPL is established. An ML classifier trained on experimental data predicts CPL activity with 0.916 accuracy. SHapley Additive exPlanations (SHAP) analysis identifies key DES molecular descriptors, guiding the discovery of novel materials that exhibit a record-high luminescence dissymmetry factor (g lum ) of 0.222 for nucleotide-based systems and achieve chirality inversion via DES modulation. The Sure Independence Screening and Sparsifying Operator (SISSO) algorithm further yields interpretable design formulas. Leveraging the distinct polarization of these gels, we demonstrate a fourth-level anti-counterfeiting strategy, decrypting concealed information via Morse and ASCII codes to enhance information security. This ML-driven methodology accelerates the discovery of high-performance CPL materials and opens new design avenues.
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高影响因子
ADVANCED MATERIALS
·
2026
·
IF 29.1
Yaru Yue,Tianbiao Liang,Canglang Yao,Jihe Tang,Feng Li,Yao Huo,Ducai Wang,Peiji Liu,Sangjin Yang,Xin Fan,Xiaoxue Lin,Dong Wang,Kuan Sun,Changduk Yang,Huajun Cao,Shanshan Chen
The development of conductive polymers that simultaneously achieve high electrical conductivity and tissue-like stretchability represents a persistent challenge in bioelectronics. Here, we demonstrate an “anchoring-buffering” molecular design strategy that overcomes this limitation through rationally designed in situ polymerizable hydroxyalkyl acrylate (HAX) dopants in poly(3,4-ethylenedioxythiophene): polystyrene sulfonate (PEDOT: PSS). Our dopant architecture features rigid acrylate groups that are inferred to maintain conjugation pathways by preferentially interacting with less conjugated PEDOT regions, and hydroxyl-terminated alkyl spacers that form a dynamic hydrogen-bond network for strain dissipation. By systematically varying alkyl chain lengths (HA0 to HA4), we optimize electrostatic screening to improve doping efficiency and π-stacking order, achieving a composite film with exceptional performance (850 S/cm conductivity and 88% elongation) that surpasses existing stretchable conductive polymers. When integrated into conformal biointerfaces, the electrode maintains stable electrophysiological signal acquisition (EMG/ECG/EEG) with 99.5% gesture recognition accuracy after 24 h of continuous wear, establishing a general molecular design framework to decouple conductivity and stretchability for next-generation wearable and implantable electronics.
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ADVANCED FUNCTIONAL MATERIALS
·
2026
·
IF 19.9
Rui Xu,Jingcheng Huang,Junhao Zhao,Shouyi Dou,Zhiheng Zhu,Zheng Shen,Heng Zhang,Lingjun Geng,Jiashuai Sun,Dianbin Su,Jicheng Zhao,Fangling Du,Xia Sun,Yemin Guo,Jianfeng Ping
Organophosphorus pesticides (OPs) are widely applied for crop pest control, but human health and the environment are seriously threatened by their excessive use. Therefore, rapid detection of pesticide residues is of great importance. In this work, a flexible aptasensor was developed by integrating an indium oxide electrolyte-gated field-effect transistor (EG-FET) with a surface-adhered DNA hydrogel obtained via rolling circle amplification (RCA) for in situ detection of OPs residues. The target pesticides were specifically recognized by the responsive DNA hydrogel, which underwent structural collapse and consequently modulated carrier depletion in the n-type FET channel. Furthermore, a wireless detection device based on a dual-channel potentiostat and a smartphone-based human-machine interface was established, enabling the detection of four OPs, including omethoate (OMT), phorate (PHO), isocarbophos (ICP), and chlorpyrifos (CPF). The EG-FET aptasensor exhibited a good linear relationship between signal response and pesticide concentration in the range of 1 pg/mL–10 ng/mL, with the limit of detection of 0.244, 0.273, 0.132, and 0.301 pg/mL, respectively. The developed device was characterized by compactness and low-cost fabrication. This work proposes a new approach to detecting small-molecule contaminants, opening avenues for transforming agricultural, food safety, and environmental monitoring from passive post-event detection to active process control.
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Advanced Healthcare Materials
·
2026
·
IF 11
Zi Zhu,Dan Yang,Hao Sun,Nizhaoyue Wei,Zhenkun Fu,Jia Zhang,Zhangdi Yan,Piaoping Yang,He Ding,Lei Zhong
Tumor immunotherapy exerts transformative effects in cancer treatment by leveraging intrinsic immunity and acting broadly effective across cancers, while first-line chemotherapy plays a direct role by disrupting tumor DNA and reducing burden. However, the clinical utility of immunotherapy is notably constrained by the immunosuppressive tumor microenvironment (ITME), while chemotherapy suffers from intrinsic systemic toxicity and acquired resistance. Herein, multifunctional nanozymes on cerium oxide sacrificial templates were designed via precursor engineering, with zirconium introduced to leverage the Kirkendall effect, whereby differing migration rates of zirconium and cerium ions form hierarchical porous structures. Accordingly, such structural features facilitate efficient mass transfer, thereby notably enhancing their triple enzymatic activity. Hierarchical architectures, coupled with hyaluronic acid moieties, further enable high-capacity cisplatin loading and high-specificity tumor targeting, effectively addressing poor drug delivery and off-target issues. Moreover, ultrasound-amplified redox homeostasis modulation driven by the nanozymes’ enzymatic activity acts as a key regulator for disrupting tumor cell redox balance. Meanwhile, synergy between oxidative stress and cisplatin-induced DNA damage acts as a dual stimulus to intervene in tumor survival pathways, not only reversing ITME but also mitigating chemotherapy-associated limitations, thereby fostering concurrent tumor cell death and immunogenic cell death and consequently highlighting promising prospects for malignancy therapy.
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Advanced Science
·
2026
·
IF 14.1
Yujie Huang,Huangzhe Dai,Chengqian Zhang,Daofan Tang,Xinxin Zhang,Haonan Sun,Annan Ding,Xuebin Ni,Yizhi Zhang,Chengfeng Pan,Peng Zhao
Magnetic tactile sensor with centripetally magnetization designs is capable of efficient 3D force decoupling sensing, which is essential for advancing robotic dexterity. Nevertheless, the miniaturization of sensors remains a challenge, primarily due to the complexities associated with precisely fabricating such planar magnetic structures. Here, we present a laser-assisted folding and magnetization (LAFM) method to create centripetally magnetized films. Laser-etched grooves enable controlled folding, achieving accurate magnetization alignment in films as small as 5 × 5 mm 2 , which are verified by root mean square errors (RMSEs) of less than 5 µT between the experimental and theoretical magnetic field values. This breakthrough enabled the compact 3D force sensor featuring high force resolution (tangential 3 mN, normal 9 mN), rapid response (34 ms), and long-term stability (>2500 cycles, <1% deviation). When installed on a mobile manipulator, the sensor enables adaptive grasping of delicate objects during obstacle traversal. Its functionality is further enhanced by deploying an array of 16 units on a dexterous hand, which supports non-destructive stiffness recognition across six representative materials and stable manipulation of variable-mass or irregular objects. This work establishes a robust pathway for miniaturized tactile sensors and embodied intelligence, especially in robotic perception.
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高影响因子
ADVANCED FUNCTIONAL MATERIALS
·
2026
·
IF 19.9
Qinghe Li,Lilin Yang,Hongyuan Sha,Dongling Yang,Zujian Wang,Xiaoming Yang,Rongbing Su,Bin Su,Chao He,Xifa Long
In the solar-blind region, the development of short-wave ultraviolet (UV) lasers relies critically on high-performance nonlinear optical (NLO) crystals, which require a wide bandgap, a strong second harmonic generation (SHG) response, and a sufficient birefringence to fulfil phase-matching requirements. Although sulfates possess a wide bandgap necessary for short-wave UV applications, the inherent symmetry of [SO 4 ] 2− tetrahedron typically results in an insufficient birefringence. To optimize their birefringence, the introduction of π -conjugated ligands was implemented with a good structural inducer of 4-hydroxypyridine group. It is an effective strategy to markedly augment the birefringence of sulfates as demonstrated in (C 5 H 5 NO) 2 ZnSO 4 ·H 2 O crystal with a birefringence of 0.48 @ 546 nm. Then, based on it, a new UV NLO crystal, (C 5 H 5 NO)ZnSO 4 ·3H 2 O, was obtained by modulating the coordination mode of zinc atoms to mitigate the steric hindrance and increase hydrogen bond sites. It achieves the collaborative optimization of SHG response (1.5 × KH 2 PO 4 (± 0.1)) and optical anisotropy (birefringence ∼ 0.27 @ 546 nm), originating from the synergetic contribution of 4-hydroxypyridine ligands and [SO 4 ] 2− groups. Therefore, this study establishes an innovative strategy for the structural design and performance optimization in NLO materials.
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高影响因子
ADVANCED MATERIALS
·
2026
·
IF 29.1
Huilin Chen,Chenliang Li,Qian Zhu,Yuzhen Wang,Zhiguo Xia
Sensing temperature using fluorescent materials by monitoring alterations in temperature-dependent luminescence characteristics is of great importance for various application fields, including modern industry, scientific research, and daily life. However, there are two main concerns on optical thermometry, and one is the low sensitivity, particularly at elevated temperatures, failing to meet precise measurement demands; another issue is how we can apply the thermometry in in situ environments. Herein, we design and report a hybrid manganese-based halide thermometry exhibiting a relative sensitivity (S r ) of 26.368% K − 1 at 463 K. We further propose a facile synthesis method for photopolymerizable hydrogel films containing the crystallized manganese-based halide thermometry, maintaining the same luminescence and sensing property. The luminescent gel film is applied to chip-based temperature sensing, demonstrating highly accurate performances as smart sensors and flexible electronic materials. This work opens up a new route to design luminescent metal halide thermometry to enrich the library of temperature sensing. Moreover, the luminescent gel film as optical thermometry can be applied in situ from micro-electronics to large-scale industrial systems, supplying new possibilities for advanced sensing and spectroscopy studies.
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Advanced Healthcare Materials
·
2026
·
IF 11
He-Ping Zuo,Jia Yang,Wei Zhao,Min Yang
Sepsis-associated intestinal injury represents a critical pathological event contributing to multiple organ dysfunction, with its pathogenesis closely linked to excessive oxidative stress and hyperactivated endoplasmic reticulum stress. Current clinical interventions lack the capacity for precise modulation of the intestinal microenvironment, while existing nanozyme systems generally face challenges such as low oral delivery efficiency, insufficient stability, and uncertain biosafety. To address these limitations, we developed a novel oral nanozyme delivery system based on 2D V 2 C MXene. Through surface modification with hydroxyethyl cellulose (HEC), we constructed a V 2 C@HEC (CV) nanozyme with enhanced physiological stability and intestinal mucoadhesion. In both in vitro and in vivo studies, the CV nanozyme demonstrated significant reactive oxygen species (ROS)-scavenging capacity. Oral administration of CV effectively mitigated intestinal barrier damage and improved survival in a septic mouse model. Mechanistic investigations suggested that the protective effects of CV may be associated with ROS clearance and modulation of endoplasmic reticulum stress, with inhibition of the ATF6/CHOP signaling pathway potentially serving as one underlying mechanism for its cytoprotective function. In summary, this study not only presents a novel nanozyme material with favorable biocompatibility, excellent stability, and a defined antioxidant mechanism, but also provides an innovative materials-based strategy for the treatment of sepsis.
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高影响因子
Small
·
2026
·
IF 11.8
Haolin Wu,Xinying Li,Bin Wang,Hongbin Liu,Fan Wang,Amr F. M. Ibrahim,Shenglai Zhong,Rongfei Zhou,Weihong Xing,Miao Yu
Assembling the nanochannels of microporous crystalline materials in continuous membranes/coatings has broad applications for separation, selective catalysis, and sensing. Current hydrothermal/solvothermal synthesis methods, however, suffer from long synthesis time, typically hours or days, leading to low fabrication efficiency and intensive energy consumption. Herein, we report an ultrafast synthesis strategy to prepare continuous molecular-sieving membranes, reducing synthesis time to just one to a few minutes—nearly two orders of magnitude faster than traditional ones. This was realized through a combination of a nuclei-loaded seed layer and a drastically increased crystallization rate, preventing substantial dissolution of the seed layer and successfully incorporating it into the resulting membranes. Utilizing this strategy, high-quality zeolite membranes-exhibiting breakthrough separation performance compared to previously reported ones, were rapidly prepared. Interestingly, ultrathin oriented zeolite membranes with ultrahigh separation performance were also prepared in as little as one minute. The drastically shortened synthesis time, together with the demonstrated reproducibility, highlights the practical potential of the UFS strategy for molecular-sieving membranes and coatings.
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高影响因子
JOURNAL OF POLYMER SCIENCE
·
2026
·
IF 3.9
Hongtao Lu,Lei Gong,Bingbing Cao,Jianna Bao
In this study, poly(lactic acid)-based polyurethanes (PLA-based PUs) made from poly( d -lactic acid) (PDLA) with molecular weights of 2, 5, and 10 kg/mol were melt-blended with poly( l -lactic acid) (PLLA) to enhance its toughness without any additional compatibilizers. The properties of the PLLA/PU blends were systematically investigated considering the M n, PDLA . The results showed that too low or too high M n, PDLA was unfavorable to the original toughness of PLA-based PU and its corresponding toughness of blends owing to their ratio of hard/soft segments, while its tensile strength remained high (> 45 MPa) regardless of M n, PDLA . Given this optimal M n, PDLA of 5 kg/mol, the PLLA/PU blends without and with stereocomplex (SC) crystallites exhibited an elongation at break of 138.3% and 282.5%, respectively, while the latter was 48 times greater than that of neat PLLA. Due to the presence of SC crystallites, the blends showed a fast crystallization rate, which crystallized within 1.2 min, whereas neat PLLA required 53.7 min. The presence of SC crystals increased complex viscosity, which further rose with increasing M n, PDLA due to the higher extent of SC crystallization. This work may provide a strategy for developing PLA-based materials with enhanced toughness. Graphical By incorporating PLA-based PU (PDBU) containing PDLA with different molecular weights, the interfacial interactions are enhanced. The formation of SC crystallites serves as nucleation sites during PLLA crystallization, leading to a reduction in spherulite size. The toughness of PLLA is remarkably improved, with PU-5k-D increasing the elongation at break by approximately 48 times.
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Small Methods
·
2026
·
IF 8.7
Tianshun Ding,Shi Feng,Hao Li,Zelong Zhang,Shengyang Tao
Chiral materials have broad applications in optics. Precise regulation of the chiral signal, however, remains highly challenging. Herein, a microfluidic strategy is proposed in which the cooperative action of dual driving forces regulates vortical flow inside droplets. The flow rate and interfacial tension are adjusted to induce ordered Marangoni convection and shear flow within microdroplets. Under these conditions, chiral signals are transmitted both within droplets and across the liquid-liquid interface. Tetrakis(4-sulfonatophenyl)porphyrin and phenethylamine are employed as a supramolecular co-assembly pair to probe the relation between vortex strength/distribution and chiral-signal transfer. Assemblies obtained under microdroplet vortex fields exhibit markedly enhanced and nearly mirror-image circular dichroism (CD) responses in comparison with those prepared under conventional magnetic stirring. These observations confirm that vortical flow efficiently promotes chiral amplification and enantioselective supramolecular assembly. Flow-field visualization by micro-particle image velocimetry (μ-PIV), combined with hydrodynamic analysis, reveals the formation mechanism and evolution of microvortices under the dual driving forces. Overall, this study demonstrates a practical approach to modulating supramolecular chiroptical signals via vortexes in confined environments.
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高影响因子
RARE METALS
·
2026
·Vol. 45
·期 4
·e70216
·
IF 12.1
Chong Chen,Chen Peng,Lin Fu,Fan Cui,Wenqi Zhu,Yichen Li,Lei Xiao,Jun Di,Guigao Liu,Wei Jiang,Hongfeng Ji,Gazi Hao
en This link goes to a English section zh This link goes to a Chinese section To address the issues of aluminum (Al) powder agglomeration during combustion and low oxidizer decomposition efficiency in composite solid propellants, this study utilized in situ self-assembly technology to prepare cobalt-based hybrid-coated modified Al powder (Al@CZ). It systematically investigated its regulatory mechanism on the combustion performance of ammonium perchlorate (AP) and ammonium dinitramide (ADN)-based propellants. Characterization results indicate that Co 2+ and 2-methylimidazole form an amorphous coating layer at the dopamine polymerization interface, with variable thickness accompanied by a gradient of Co 2+ loading. Thermal analysis shows that the modified Al may trigger a thermite reaction at the interface in air, reducing the high-temperature oxidation peak. The modified Al exhibits significant catalytic efficiency for the high-temperature decomposition of AP, with the activation energy reduced by up to 34.7% and the peak temperature advanced by 78°C. However, its catalytic effect on ADN is relatively weak. In the propellant system, Al@CZ reduces the width of the exothermic peak of AP-based propellants, increases the burning rate by 10.4%, and decreases the median particle size of the condensed-phase products by 92.1%; for ADN-based propellants, it significantly improves combustion stability, with the maximum pressure increasing by 1.1 times and the pressure rise rate improving by 6.4 times. Combustion mechanism analysis confirms that the coating accelerates Al core oxidation and reduces combustion surface residence time through the synergistic effect of catalytic decomposition of oxidants and interfacial thermite reactions, effectively suppressing molten agglomeration. This study provides a new strategy for controllable combustion regulation in high-energy solid propellants. 摘要 en This link goes to a English section zh This link goes to a Chinese section 为解决复合固体推进剂中铝粉燃烧团聚及氧化剂热分解效率低的问题, 本研究采用原位自组装技术制备了钴基杂化改性铝 (Al@CZ) , 系统研究了改性铝对高氯酸铵 (AP) 和二硝酰胺铵 (ADN) 推进剂燃烧性能的调控机制。测试结果表明, Co 2+ 与2-甲基咪唑在多巴胺聚合界面形成非晶包覆层, 其厚度随Co 2+ 负载量梯度变化。热分析显示, 改性铝粉在空气中可能引发界面铝热反应, 从而降低高温氧化峰值。改性铝对AP高温分解展现显著催化效率, 使活化能降低34.7%, 峰值温度提前78°C。但其对ADN的催化效果相对较弱。在推进剂体系中, Al@CZ可缩短AP基推进剂放热峰宽, 使燃烧速率提升10.4%, 并使凝结相产物中值粒径缩小92.1%; 对于ADN基推进剂, 显著改善了燃烧稳定性, 最大压力提升1.1倍, 增压速率提高6.4倍。燃烧机理分析证实, 该包覆层通过催化氧化剂分解与界面铝热反应的协同作用, 加速铝芯氧化并缩短熔融铝在燃面停留的时间, 有效抑制熔融聚结。本研究为界面工程调控固体推进剂的燃烧提供了新策略。
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危险品化学品经营许可证（带存储）