PLANT PHYSIOLOGY AND BIOCHEMISTRY
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2026
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IF 6.2
Jingyang Ding,Xue Wang,Haiyan Li,Guisheng Xiang,Shiyan Yuan,Yongkang Zhang,Xianbin Deng,Zihan Yang,Bing Hao,Shengchao Yang,Xiaobo Li,Guanghui Zhang
Dipterocarpaceae dammar resins contain diverse triterpenoids, including dammarane constituents and scaffolds other than dammarane, such as derivatives with oleanane, ursane or lupane scaffolds, but the oxidosqualene cyclases (OSCs) underlying this scaffold diversity remain poorly characterized. OSCs catalyze the cyclization of 2,3-oxidosqualene to generate distinct triterpene scaffolds. Genome mining identified 13 putative PcOSC genes in Parashorea chinensis . Guided by triterpenoid scaffold information from accessible leaf and stem tissues and by phylogenetic placement, we prioritized a PcOSC clade related to amyrin formation and a branch related to cycloartenol and sterol biosynthesis for functional analysis. Yeast expression assigned PcOSC10 as a cycloartenol synthase, PcOSC4 as a β -amyrin synthase, and PcOSC3 as a multifunctional α / β -amyrin synthase. Transient expression in Nicotiana benthamiana provided complementary evidence from a plant host for PcOSC3 and PcOSC4, whereas the cycloartenol signal associated with PcOSC10 expression was interpreted relative to the matched control because cycloartenol is an endogenous sterol intermediate in plant tissues. Key residue analysis identified residues associated with scaffold outcome and product output. PcOSC3 M729N shifted products from amyrins to lupeol, PcOSC4 K729N enabled germanicol formation, and PcOSC4 L483I increased β- amyrin output by approximately 4.3-fold under the tested yeast expression conditions. Together, these data define representative PcOSCs involved in amyrin formation and in the cycloartenol/sterol-related branch and identify residues associated with OSC scaffold choice and product output. Although the branch responsible for dammarane formation remains to be resolved by separate functional characterization, the present study provides an initial framework guided by metabolite information and phylogenetic analysis for dissecting triterpenoid scaffold diversification controlled by OSCs in Dipterocarpaceae.
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AICHE JOURNAL
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2026
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IF 4.4
Long Tang,Bingqiang Huang,Xinyi Chen,Yihan Yin,Shupanxiang Chen,Yanqun Ren,Hongxia Gao,Zhiwu Liang
In this work, a three-dimensional (3D) computational fluid dynamics (CFD) model incorporating wetting phenomena and a resistance-in-series framework was developed for CO 2 absorption in hollow fiber membrane contactors (HFMCs). Validated against experimental flux data, simulations identify wetted membrane resistance as the dominant bottleneck, accounting for 70%–92% of the total resistance. Reducing fiber diameter or increasing liquid flow rate boosts lumen velocity, significantly enhancing flux by mitigating this resistance. While higher amine concentrations improve reaction kinetics, they simultaneously elevate membrane wetting risks. Additionally, high-intensity gas flow operations reach a “mass transfer plateau.” Finally, an empirical correlation linking wetting rate to log-mean pressure drop was established to guide design. This study offers a validated framework for optimizing efficient, stable amine-based CO 2 capture systems.
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Journal of Physical Chemistry Letters
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2026
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IF 4.5
Liyuan Wang,Zhishun Feng,Shiji Li,Hongsheng Liu,Yanying Ren,Junfeng Gao,Lei Li
Silver nanoparticles hold great promise in biomedical and environmental applications, yet small and uniform Ag nanoclusters are hindered by easy aggregation, uncontrollable growth, and difficult recovery. Here we report a rapid and controllable ultrasmall (1–4.5 nm) Ag nanocluster by uniformly dispersed encapsulation in ZSM-5 channels using a microwave-assisted one-pot synthesis strategy. The ZSM-5 containing 1.21 wt % Ag nanoclusters exhibits a high Ag atomic utilization rate of 81.2%. The unique confinement structure effectively prevents Ag nanocluster overgrowth while conferring exceptional recyclability, maintaining over 99.9% bactericidal efficacy against Escherichia coli after three cycles. Performance testing reveals the material exhibits remarkable peroxidase-like activity (3.73 U/mg) and catalytic capability (methylene blue reduction rate constant of 0.167 min–1). This study offers a size-controllable approach for preparing high-performance, easily recoverable, and scalable Ag-based nanomaterials.
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Journal of Environmental Chemical Engineering
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2026
·Vol. 14
·期 5
·123736
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IF 7.5
Hao Wang,Huifeng Deng,Shenghong Lai,Jiahui Li,Menghong Xie,Jiazhen Wei,Guihua Ruan,Yipeng Huang
In recent years, lead ion (Pb 2+ ) pollution control technologies have continued to advance. Among them, the adsorption method has shown promising application prospects. However, existing adsorption methods focus solely on Pb 2+ removal while neglecting the subsequent transformation and functionalization of the recovered Pb 2+ . To address these issues, thiol-functionalized covalent organic frameworks (COFs) were synthesized for recovery of Pb 2+ and confined conversion of Pb 2+ to CsPbBr 3 nanocrystals (NCs), an optoelectronic material. The effects of morphologies and surface chemistry of COFs on the adsorption efficiency for Pb 2+ were studied. The morphology tuning of COFs from spherical shape to flower shape with a myriad of humps on the surface boosted the adsorption efficiency for Pb 2+ from 25% to 85%. After thiol modification by 1,2-ethanedithiol, the adsorption efficiency of COFs for Pb 2+ increased by nearly 10-fold. The maximum adsorption capacity of thiol-functionalized COFs for Pb 2+ was 54.3 mg·g −1 . The adsorption isotherm was best described by the Langmuir model. Utilizing the mesopore-confined effect of COFs, the enriched Pb 2+ were converted into CsPbBr 3 NCs. The CsPbBr 3 NCs confined in COFs exhibited excellent stability and could generate singlet oxygen ( 1 O 2 ) under the irradiation by xenon lamp, revealing their potential applications in photocatalysis, bacteriostasis, light emitting diode and sensing. This work provides a prototype for both the removal and recycling of polluted Pb 2+ .
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ADVANCED FUNCTIONAL MATERIALS
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2026
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IF 19.9
Tianbao Liu,Jiao Sun,Weiguang Shi,Zhaohui Dong,Yu Wang,Lili Zhang,Eddy Dib,Shaohua Zhou,Peng Bai,Svetlana Mintova,Biao Dong
Propane dehydrogenation (PDH) to propylene is constrained by the trade-off between catalyst activity, selectivity, and stability, especially for non-precious metals. Herein, a ZnAl-layered double oxide/montmorillonite (ZnAl-LDO/MMT) heterojunction catalyst is designed via interfacial electrostatic self-assembly. A built-in electric field (BIEF) is constructed at the heterointerface, which drives directional electron transfer. This unique configuration effectively inhibits the over-reduction of Zn 2+ to volatile Zn 0 , thereby stabilizing the active centers. The optimal catalyst delivers a propane conversion of 69.61% with a propylene selectivity of 88.5% at 575°C, achieving a propylene space-time yield (2.06 mmol·g −1 ·h −1 , normalized to the active component) that is ten times higher than that of the ZnAl-LDO reference. Remarkably, it maintains stable performance over 55 reaction-regeneration cycles. In situ characterizations, combined with density functional theory (DFT), reveal that the enhanced performance is consistent with the computational result of a 0.97 eV upshift in the d-band center of ZnAl-LDO upon compositing with MMT, which strengthens propane adsorption. In situ FT-IR and Raman results suggest that interfacial engineering via the BIEF, likely promotes the formation of specific Zn─O X ─Si active sites, thereby selectively producing propylene while suppressing CO 2 formation at 300°C. This work reports a BIEF engineering strategy for designing non-precious metal PDH catalysts, which demonstrates enhanced activity and stability.
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Nature Communications
·
2026
·
IF 18.1
Luo Jiawei,Liu Yuhang,Zhang Jingchao,Liu Zhedong,Guo Zhaoxin,Qian Kunyan,Li Zekun,Huang Pengfei,Wang Chunying,Zeng Jianrong,Liu Rui,Chen Yanan,Ding Jia,Hu Wenbin
Polyanionic positive electrodes with XO 4 (X = P, S, Si etc.) tetrahedra exhibit beneficial properties, making them crucial for energy storage systems. However, strong covalent X-O bonds cause electron localization, reducing intrinsic electronic conductivity and limiting rate performance. Here we show a strategy to directional design the covalency of X-O bonds for enhanced intrinsic electronic conductivity of polyanionic positive electrodes. We developed a non-equilibrium fast calcination technique to synthesize polyanionic positive electrodes inheriting weak covalent (WC) X-O bond characteristics from screened precursor. In as-synthesized NASICON-Na 3 V 2 O 1.6 (PO 4 ) 2 F 1.4 as proof-of-concept positive electrode, the WC P-O bonds effectively activate electron delocalization, thereby increasing electrons transport capability along V-O-P-O-V pathway. The intrinsic electronic conductivity of optimised material achieves 3.57 times enhancement, leading to 3.70 times and 3.86 times improvement in specific capacity and specific energy at 50 C. Meanwhile, the optimised material exhibits capacity retention of 85.9% after 3000 cycles at 1 C. This study potentially opens up a broad space for improving the intrinsic conductivity of polyanionic materials (such as phosphates, sulfates, silicates, etc.), with the potential to promote the development of next-generation high-power positive electrode.
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CHEMISTRY OF MATERIALS
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2026
·
IF 7.1
Qian Yang,Zhuoying Chen,Ziyao Mao,Guangzhao Li,Lijing Hao,Yunhua Chen
Mesenchymal stem cells (MSCs) have attracted considerable interest for therapeutic delivery owing to their multilineage differentiation capacity, low immunogenicity, and broad immunomodulatory functions. However, the development of biomaterials that simultaneously enable efficient stem cell encapsulation, minimally invasive delivery, and improved retention remains a significant challenge. Herein, we report a supramolecular granular hydrogel matrix with an intrinsic macroporous architecture designed to enhance the MSC viability and in vivo retention. The resulting granular hydrogel exhibits robust self-healing and dynamic mechanical properties arising from reversible physical interactions and can be readily processed as a three-dimensional (3D) printable ink for continuous and stable extrusion. This granular hydrogel supports long-term 3D culture of MSCs and markedly enhances cell adhesion and stemness maintenance compared with conventional two-dimensional culture conditions. In a murine cell delivery model, MSC-laden GMU granular hydrogels maintained a stable 3D matrix following injection, leading to significantly improved cell retention in vivo. These results demonstrate that the GMU granular hydrogel is a promising carrier platform for stem cell delivery and regenerative therapy.
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JOURNAL OF NATURAL PRODUCTS
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2026
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IF 3.7
Yuling Zeng,Jing Nie,Haiyan Lan,Yichao Zhang,Yufang Dai,Xiaojie Cao,Liang Zhang,Jianjian Hu
Camphor is a key quality determinant of lavender oil. Bornyl dehydrogenase (BDH) catalyzes the final camphor biosynthesis step, yet its gene family and mechanism in lavender remain uncharacterized. We phylogenetically classified 154 short-chain dehydrogenase/reductase (SDR) genes into six clades and screened 17 BDH genes. Integrated transcriptomic and metabolomic analyses revealed that camphor biosynthesis primarily occurs via the plastidic 2-C-methyl-D-erythritol 4-phosphate (MEP) pathway, with coordinated expression of geranyl diphosphate synthase (GPPS), bornyl diphosphate synthases (BPPS), bornyl-diphosphate diphosphatase (BDD), and BDH genes. Most biosynthetic genes, especially BDH and BPPS, were significantly upregulated in L. × intermedia “Xinxun 4”, correlating with its highest camphor content. Subcellular localization showed BDH1 resides in the cytoplasm, suggesting plastid-cytoplasm collaboration. In vitro assays demonstrated that BDH1 and BDH2 both oxidize (+)- and (−)-borneol to camphor. Molecular dynamics simulations revealed that BDH1’s active site exhibits conformational flexibility, accommodating both enantiomers with similar binding affinities, which was confirmed by enzyme kinetics. Asn90 was identified as a key catalytic residue. These findings reveal BDH family expansion, coordinated gene expression driving camphor accumulation, and BDH1’s catalytic flexibility, offering key genetic resources and mechanistic insights for optimizing lavender camphor content via metabolic engineering and molecular breeding.
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CHEMICAL ENGINEERING JOURNAL
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2026
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IF 12.5
Yi Wei,Jiawei Shen,HengZhe Ma,Fengsheng Zhan,Lingxia Zheng,Jianbing Ji
Highly efficient methane pyrolysis is achieved at 580 °C in a molten salt nickel metal fog system. • The catalytic performance at 580 °C maintained stable over 60 h. • Apparent activation energy is minimized to 97.6 kJ·mol −1 in the process. Methane pyrolysis has become a research hotspot in recent years due to its ability to produce hydrogen and valuable carbon byproducts with minimal direct CO 2 emissions. This study constructs a molten salt nickel metal fog catalytic system in a bubble-cap reactor for methane pyrolysis. The ionic liquid environment formed by molten carbonates dissolves nickel powder to form nanoscale active clusters, improving the dispersibility of the catalyst greatly. Meanwhile, the bubble-cap reactor disperses methane bubbles, further enhancing the contact efficiency between methane bubbles and nickel metal fog. Experimental results show that this system achieves 88.3% methane conversion at 580 °C and maintains catalytic activity for over 60 h under continuous operation. The formation of Ni metal fog improves both catalytic efficiency and economic viability, presenting a promising strategy for methane pyrolysis technology. Download: Download high-res image (158KB) Download: Download full-size image
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POLYMER
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2026
·
IF 5.1
Zishuo Wu,Haotian Wu,Lei Wu,Yuqi Xiong,Chengyan Li,Tingyu Xu,Xiaojie Chen,Wei Chen
While the mechanical properties of polymer gels are typically ascribed to the polymer network, the role of solvent dynamics—the majority component—remains elusive due to the lack of in-situ selective probing techniques. Here, by integrating operando Rheo-NMR with synchrotron radiation X-ray scattering (SRXS), we reveal a temperature-dependent coupling between macroscopic deformation and microscopic solvent confinement. Our results demonstrate a distinct bifurcation in behavior: at lower temperatures, the solvent dynamics remain relatively unperturbed as the network undergoes limited reorganization. However, at elevated temperatures ( T ≥ 100 °C), a striking restriction of glycerol mobility is observed. In-situ SRXS uncovers the structural origin of this phenomenon: it stems from a competition between stretching-induced crystallite fragmentation and crystallization within the PVA network. At these elevated temperatures, crystallization is favored over fragmentation, resulting in a more constrained crystalline network environment that directly governs the solvent's rotational mobility. By establishing a direct correlation between stretching-induced structural evolution and solvent dynamics, this work offers a new perspective for designing high-performance soft materials through 'solvent engineering'.
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APPLIED CATALYSIS A-GENERAL
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2026
·
IF 4.8
Jingyi Chen,Shuangfeng Ren,Luyao Guo,Tongtong Feng,Xiaoling Mou,Jiaxu Liu,Li Yan,Ronghe Lin,Yunjie Ding
Hydrothermal defect healing selectively stabilizes catalytically active Pt ensembles by removing weakly anchored species in Silicalite-1. • Confined Pt ensembles exhibit enhanced intrinsic activity, lower activation energy, and improved oxygen activation in aerobic alcohol oxidation. • Catalysis occurs on externally accessible Pt sites and mesoporous regions, enabling efficient oxidation of bulky alcohol molecules. • Defect-healing-induced restructuring provides a general strategy to optimize active site stability and catalytic efficiency in heterogeneous oxidation catalysts. The development of robust Pt catalysts that simultaneously achieve efficient O 2 activation, high intrinsic activity, and structural stability remains a central challenge in aerobic alcohol oxidation. Herein, we report a hydrothermal defect-healing strategy to restructure impregnated weakly anchored Pt species in Silicalite-1 zeolite into highly stable Pt ensembles confined within the zeolite framework (Pt@S-1). Spectroscopic and microscopic analyses reveal that hydrothermal treatment heals silanol defects and drives controlled restructuring of isolated Pt atoms into small ensembles strongly stabilized by the zeolitic microenvironment. The resulting Pt@S-1 catalyst exhibits markedly enhanced intrinsic activity, achieving a turnover frequency of 5560 h −1 in aqueous aerobic oxidation of 3,5,5-trimethylhexanol, exceeding conventional nanoparticle and impregnated analogues by over one order of magnitude despite significantly lower Pt loading. Kinetic studies demonstrate a reduced apparent activation energy (65.7 kJ mol −1 ) and nearly first-order dependence on O 2 pressure, indicating facilitated O 2 activation and optimized competitive adsorption between oxygen and alcohol substrates. The zeolite confinement and aqueous reaction medium synergistically promote selective formation of isononanoic acid and ester while suppressing catalyst sintering and thermal runaway. Furthermore, the catalyst shows excellent stability without requiring hydrogen pretreatment or additional base. This work establishes defect-healing-induced restructuring as an effective approach to generate stable and highly active catalytic ensembles from labile atomically dispersed precursors and provides fundamental insights into structure–activity relationships governing selective aerobic alcohol oxidation. Download: Download high-res image (150KB) Download: Download full-size image A hydrophilic zeolite-supported Pt catalyst cooperates with water to drive base-free and H 2 -free aerobic oxidation of long-chain alcohols under mild aqueous conditions, achieving selective acid formation while suppressing energy demand, metal sintering, and organic solvent use.
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Journal of Future Foods
·
2026
·
IF 10.6
Fang Liu,Liu Wan,Jiamin Wang,Zheng Ping,Shuaiyin Chen,Luming Zhao,He Sun,Haiyan Yang
Butyrate deficiency has important implications in physiology and disease. Using dietary interventions to overcome butyrate insufficiency has been attempted for decades. Dozens of dietary fibers (DF) rich in non-digestible carbohydrates (NDC) possess butyrogenic properties. However, their relative strength in stimulating butyrate production has yet to be systematically compared in vivo . Here we evaluated the butyrogenic properties of nine widely used NDC in modifying colitic symptoms in mice. We ranked their relative strength in stimulating butyrate production under both healthy and colitic conditions. Our longitudinal data modelled trajectories of each NDC tested in promoting butyrate production under both health conditions. Our data demonstrated that NDC supplementation resulted in 1.69 times higher butyrate in healthy than colitic mice ( P = 7.49×10 −4 ), underscoring the importance of health status-dependent selection of optimal NDC in designing clinical trials. The mice supplemented with fructooligosaccharides (FOS), and β-glucan, resistant starch 3 (RS3) had the highest butyrogenic strength at 157.11%, 154.07%, and 152.42%, respectively, compared to the mice fed the basal diet (100%). These DF modified colitic phenotypes, including reducing serum LPS concentrations and repressing intestinal inflammation. The ability of these NDC in modulating gut microbiota varies substantially, depending on interactions between specific DF types and host health status. The full-length 16S rRNA gene sequencing-based approach used allowed us to identify microbiota features at species and strain levels and to detect strong correlations between species abundance and short-chain fatty acid concentrations. Our results provide mechanistic bases for precise modulation of gut microbiota using NDC. Our findings on health status-dependent butyrogenic efficacy are of pragmatic value in designing intervention studies and recruiting volunteers in clinical trials for overcoming butyrate deficiency. Formulations of optimal NDC mixtures targeting specific butyrate biosynthesis pathways without having a broad impact on native gut microbiota can be advantageous in microbial ecology engineering.
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