JOURNAL OF NANOBIOTECHNOLOGY
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2025
·Vol. 23
·期 1
·1-17
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IF 12.6
Zhu Huan,Zhang Zhaoyuan,Jiang Rong,Xu Liangfu,Yang Xiangdi,Chen Jie,Wang Zhenning,Xu Xiao,Liu Zhigang
Radiotherapy (RT) effectiveness is limited by low DNA damage in tumor cells, surrounding tissue harm, and tumor radioresistance with active DNA repair. Herein, we have engineered a two-dimensional nanomaterial consisting of MXene nanosheets at its core, coated with gold nanorods and a cisplatin shell, and further modified with polyvinyl alcohol, referred to as APMP. The APMP exploits its distinctive electronic properties and photothermal effects to augment radiosensitivity and impede DNA damage repair mechanisms. In vitro experiments demonstrate that APMP elevates reactive oxygen species (ROS) production to approximately 2.6 times higher than that achieved with radiotherapy alone, thereby significantly enhancing the sensitivity to radiotherapy. Combining APMP with photothermal therapy (PTT) and RT is a promising glioblastoma treatment strategy, achieving tumor destruction via localized hyperthermia and overcoming radioresistance. This approach achieves precise tumor targeting, reducing side effects and enhancing therapeutic response in preclinical models. The novel core-shell design enables potent radiotherapy-specific radiosensitizers that drive immunogenic cell death, enhancing glioblastoma combination immunotherapy. This universal strategy heralds a new era in integrating radiotherapy sensitizers with immunotherapy. Graphical
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JOURNAL OF POWER SOURCES
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2024
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IF 8.1
Shaolin Yang,Panpan Fu,Zexi Chen,Ya Chen,Yajuan Feng,Jiandong Wu,Hui Lu,Chunping Hou
MXene exhibits significant promise as a cathode material for zinc-ion hybrid supercapacitors (ZHSCs) because of its remarkable physicochemical characteristics. However, the self-stacking and aggregation of two-dimensional MXene nanosheets limits the performance of ZHSCs. In this paper, MXene-reduced graphene oxide (rGO) heterostructures are prepared by a one-step method as binder-free cathode materials for ZHSCs. The integration of rGO nanosheets within MXene layers efficiently mitigates the self-stacking tendency of MXene nanosheets and widens their interlayer spacing, significantly enhancing ionic accessibility and facilitating ion transport within the structure. As a cathode material for ZHSCs, the MXene-rGO heterostructure exhibits remarkable electrochemical performance. The MXene-rGO cathode achieves a specific capacitance of up to 660 F g −1 at 0.5 A g −1 , and demonstrates an energy density of 86.4 Wh kg −1 at a power density of 222.3 W kg −1 , surpassing the majority of MXene-based cathodes previously documented for ZHSCs. The cathode also exhibits excellent cyclability with maintaining a capacity retention of 87.7 % after 10,000 cycles. The ease of production and outstanding performance of the MXene-rGO heterostructure suggests its potential as a highly promising cathode material for practical applications in ZHSCs.
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INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
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2024
·
IF 7.7
Yixuan Wu,Qingqing Yu,Xuyue Zhou,Weixiao Ding,Xinmeng Li,Peng Zhou,Yalei Qiao,Zhen Huang,Shujun Wang,Jiaan Zhang,Luyu Yang,Lei Zhang,Dongping Sun
Electrical stimulation therapy is effective in promoting wound healing by rescuing the decreased endogenous electrical field, where self-powered and miniaturized devices such as nanogenerators become the emerging trends. While high-voltage and unidirectional electric field may pose thermal effect and damage to the skin, nanogenerators with lower voltages, pulsed or bidirectional currents, and less invasive electrodes are preferred. Herein, we construct a polydopamine (PDA)-modified poly-L-lactic acid (PLLA) /MXene (PDMP/MXene) nanofibrous composite membrane that generates piezoelectric voltages matching the transepithelial potential (TEP) to accelerate wound healing. PDA coating not only enhances the piezoelectricity of PLLA by dipole attraction and alignment, but also increases its hydrophilicity and facilitates subsequent MXene adhesion for electrical conductivity and stability in physiological environment. When applied as wound dressings in mice, the PDMP/MXene membranes act as a nanogenerators with reduced internal resistances and satisfactory piezoelectric performances that resemble bioelectric potentials (~10 mV) responding to physical activities. The membrane significantly accelerates wound closure by facilitating fibroblast migration, collagen deposition and angiogenesis, and suppressing the expression of inflammatory responses. This piezoelectric fibrous membrane therefore provides a convenient solution for speeding up wound healing by sustained low voltage mimicking bioelectricity, better cell affinity.
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INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2024
·
IF 7.7
Zhaochuan Yu,Chao Deng,Chenhui Ding,Xing Zhang,Yuqian Liu,Chao Liu,Zhichao Lou,Farzad Seidi,Jingquan Han,Qiang Yong,Huining Xiao
Despite the tremendous efforts on developing antibacterial wearable textile materials containing Ti 3 C 2 T x MXene, the singular antimicrobial mechanism, poor antibacterial durability, and oxidation susceptibility of MXene limits their applications. In this context, flexible multifunctional cellulosic textiles were prepared via layer-by-layer assembly of MXene and the in-situ synthesis of zeolitic imidazolate framework-8 (ZIF-8). Specifically, the introduction of highly conductive MXene enhanced the interface interactions between the ZIF-8 layer and cellulose fibers, endowing the green-based materials with outstanding synergistic photothermal/photodynamic therapy (PTT/PDT) activity and adjustable electromagnetic interference (EMI) shielding performance. In-situ polymerization formed a MXene/ZIF-8 bilayer structure, promoting the generation of reactive oxygen species (ROS) while protecting MXene from oxidation. The as-prepared smart textile exhibited excellent bactericidal efficacy of >99.99 % against both Escherichia coli ( E. coli ) and Staphylococcus aureus ( S. aureus ) after 5 min of NIR (300 mW cm −2 ) irradiation which is below the maximum permissible exposure (MPE) limit. The sustained released Zn 2+ from the ZIF-8 layer achieved a bactericidal efficiency of over 99.99 % within 48 h without NIR light. Furthermore, this smart textile also demonstrated remarkable EMI shielding efficiency (47.7 dB). Clearly, this study provides an elaborate strategy for designing and constructing multifunctional cellulose-based materials for a variety of applications.
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INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
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2024
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IF 7.7
Tao Yuan,Zhen Zhang,Qian Liu,Xiu-Tong Liu,Shao-Qu Tao,Chun-li Yao
In recent times, there has been significant interest in the utilization of cellulose nanofiber (CNF) films as the foundation for supercapacitors due to their three-dimensional structure, flexibility and eco-friendliness. An ultrasonic and vacuum filtration method was used to prepare a hybrid film consisting of MXene (Ti 3 C 2 T x ), CNF and liquid metal (LM). The combination of CNF and LM with MXene produces a porous structure with higher electrical conductivity, which facilitates the transportation of ions and electrons within the composition and confers the material with heightened electrochemical properties. The CNF/MXene/LM electrode has a significant area capacitance of 871.3 mF cm −2 at a current density of 5 mA cm −2 . The hybrid film demonstrates excellent stability, maintaining a high conductivity of 546.4 S∙cm −1 and retaining 96.9 % capacitance after 2000 cycles at a current density of 10 mA cm −2 . By utilizing the thin film as an electrode, a high-performance quasi-solid supercapacitor was fabricated, with a remarkably thin thickness of only 0.319 mm. Supercapacitors show exceptional electrical properties, including a surface-specific capacitance of 188.2 mF cm −2 at a current density of 5 mA cm −2 . This study indicates that flexible electrodes made from cellulose nanofiber have extensive potential in the realm of supercapacitors.
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Science Advances
·
2024
·Vol. 10
·期 49
·
IF 11.7
Xu Wang,Haiguang Zhang,Gaoliang Wei,Jiajian Xing,Shuo Chen,Xie Quan
Artificial ion channels with controllable mono/monovalent cation separation fulfill important roles in biomedicine, ion separation, and energy conversion. However, it remains a daunting challenge to develop an artificial ion channel similar to biological ion channels due to ion-ion competitive transport and lack of ion-gating ability of channels. Here, we report a conductive MXene membrane with polydopamine-confined angstrom-scale channels and propose a voltage gating and ion charge comediation strategy to concurrently achieve gated and selective mono/monovalent cation separation. The membrane shows a highly switchable “on-off” ratio of ∼9.9 for K+ transport and an excellent K+/Li+ selectivity of 40.9, outperforming the ion selectivity of reported membranes with electrical gating (typically 1.5 to 6). Theoretical simulations reveal that the introduced high-charge cations such as Mg2+ enable the preferential distribution of target K+ over competing Li+ at the channel entrance, and the surface potential reduces the ionic transport energy barrier for allowing K+ to pass quickly through the channel.
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CHEMICAL ENGINEERING JOURNAL
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2024
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IF 13.3
Tianli Li,Wentao Liu,Yizhou Liu,Jian Wang,Hua Hao,Zhiyong Yu,Hanxing Liu
The paramount target in advancing high-efficiency lithium-sulfur (Li–S) batteries lies in hindering polysulfides shuttling and enhancing redox kinetics. Herein, the covalent organic frameworks (designated as TBCOF) are grafted in-situ on the surface of MXene to achieve MXene@TBCOF heterostructure at ambient temperature, modulating the kinetics behavior of ions owing to its unparalleled ionic sieving functionality. The resultant compound possesses a gradient (non-conductive/ conductive) electric field effect, well-defined porous architecture, and abundant sulfophilic/lithiophilic sites, enriching the chemical space of 0D-2D heterostructures. By harnessing the multiple-in-one characteristics of MXene@TBCOF heterostructure, the formed electron-bridge of integrated conductive MXene in heterostructures prohibits the accumulation of TBCOF and MXene, serving as a versatile accelerator for the polysulfides bidirectional evolution, as comprehensively evidenced by theoretical analysis and pouch cells. Therefore, the batteries equipped with MXene@TBCOF functional separator acquire a brilliant cyclicity at a current density of 1C (with capacity decaying rate of merely 0.0191 % per cycle) during 1500 cycles. Impressively, even with a sulfur loading up to 9.31 mg cm −2 , the batteries exhibit a superior area capacity of 7.14 mAh cm −2 after enduring 90 cycles. This work proposes an innovative one-step synthesis strategy to construct catalytic “ion-sieving” heterostructure via covalent coupling for practical Li-S batteries.
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POLYMER COMPOSITES
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2024
·
IF 4.8
Ping Han,Shaokai Hu,Chao Meng,Ying Yu,Gang Wei,Zheng Gu
Two-dimensional (2D) MXene (MX) and silane coupling agents are increasingly used to modify carbon materials for the fabrication of composite functional materials, which exhibit enhanced electrical, optical, and mechanical properties due to the synergistic effects of both MX and silane. We demonstrate the modification of carbon fibers (CFs) with MX and three different kinds of silane coupling agents, including 3-aminopropyltriethoxysilane, 3-glycidyloxypropyldimethoxymethylsilane, and 3-mercaptopropyltriethoxysilane, which are named as CF-MX@N, CF-MX@O, and CF-MX@S, respectively, and further prepare the CF-MX@silane/epoxy (EP) composites. The utilized silane coupling agents serve as bridges between MX and CFs, forming CF-MX@silane composites. Through comparative analysis, it is found that the CF-MX@S composites form a strong interface phase through covalent bonds, significantly enhancing the interface compatibility and revealing strong interface adhesion. The interfacial shear strength of the molded CF-MX@S/EP composites increases to 119.7 MPa, with an 173.9% enhancement comparing to unmodified composites. This work can offer useful guidance and reference for selecting appropriate silane coupling agent to modify CFs with 2D materials to form high-performance composite materials. Highlights Silane coupling agents are used as bridges to graft MXene-modified CFs The surface modification of CFs is achieved by a simple one-step approach Excellent interfacial phase is constructed through forming strong covalent bonds Microstructure and failure interface are responsible to interface strengthen.
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JOURNAL OF ALLOYS AND COMPOUNDS
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2025
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IF 6.3
Shibo Sun,Wenzi Huang,Huajuan Yu,Zhihao Sun,Wei Shang,Yuqing Wen
The magnesium (Mg) metal anodes of magnesium batteries have attracted significant attention because of their high theoretical capacity, high safety, and low cost. Their development is hindered by the passivation characteristics of magnesium, especially the serious voltage lag and corrosion polarization in aqueous solutions. This study demonstrates a novel approach involving the electrophoresis deposition on the surface of a magnesium electrode with MXene@ZIF-67. MXene@ZIF-67 is a heterojunction material with a core-shell structure obtained from MXene and ZIF-67 by the in-situ growth method. The addition of ZIF-67 not only solves the problem of MXene layer-to-layer instability, but also improves the corrosion resistance of magnesium metal by utilizing the properties of ZIF-67 material topology. The core-shell structure design of the modified film layer enables MXene and ZIF-67 to achieve efficient synergy. On the one hand, the unique lamellar structure of MXene is utilized to achieve uniform Mg 2 + flux and reduce the interfacial resistance of the magnesium anode, and on the other hand, the unique ionic conductor performance of ZIF-67 enables precise separation of solvent molecules and simultaneous selective Mg 2+ transport. So, the film is beneficial for interfacial stability and reaction kinetics. The modified Mg battery exhibits a reduction in voltage lag time from 7.2 seconds to 1.3 seconds. A notable reduction in polarity and enhanced stability in plating and stripping was observed in magnesium metal battery for 300 cycles. The DFT calculations show that there is a high adsorption energy between the MXene@ZIF-67 film and the magnesium alloy.
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SEPARATION AND PURIFICATION TECHNOLOGY
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2025
·
IF 9
Chengzhong Xiong,Runzhang Tao,Jian Lu,Shilong Li,Dong Zou,Yuqing Sun,Wenheng Jing
Efficient recovery of Li + from lithium-ion batteries (LiBs), which also include Co 2+ , Ni 2+ , or Mn 2+ in the cathode material, remains a formidable challenge because the sizes and physicochemical properties of these ions. Composite lamellar membranes are emerging as highly ion-selective nanochannels with controllable interlayers. Herein, Li + /Co 2+ was precisely separated through two-dimensional MXene/δ-MnO 2 composite nanochannels under an electric field. The nanochannels were constructed on tubular ceramic membranes via hydroxyl crosslinking. The membrane layer spacing can be extended to 5.7 Å by electrostatic repulsion between MXene and δ-MnO 2 nanosheets, which is suitable for Li + /Co 2+ separation. Under an electric field of 2 mA cm −2 , Li + /Co 2+ was nearly completely separated, with a high Li + flux of 0.0094 mol m -2 h −1 , and the energy consumption was ∼0.315 kW h (mol Li + ) -1 . Similarly, near-complete separation of Li + /Ni 2+ and Li + /Mn 2+ can be achieved at a current density of 2 mA cm −2 . The transport of Li + in solution was accelerated under a positive electric field and by partial dehydration in the nanopores. Meanwhile, the zeta potential was distinctly more negative in the composite membranes than in individual MXene or δ-MnO 2 . Consequently, Co 2+ was rapidly adsorbed on the negatively charged membrane surface through electrostatic interactions and complexation, forming a positively charged Co 2+ layer that electrostatically repelled further Co 2+ adsorption, ultimately achieving near-complete separation of Co 2+ . Owing to their stable and robust structure, the MXene/δ-MnO 2 membranes maintained high separation efficiency in acidic solutions containing Li + and Co 2+ and remained stable over eight cycles (up to 14 h) of ion separation under an electric field. This approach can potentially realize 2D membrane composites for efficient ion separation in practical applications.
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COMPOSITES PART A-APPLIED SCIENCE AND MANUFACTURING
·
2024
·
IF 8.1
Yunpeng Huang,Yuxi Zhang,Yidong Peng,Jiahui Sun,Jiancheng Dong,Tianxi Liu
Fiber-based wearable electronics represent an advanced technology, enabling innovative applications in flexible, lightweight, and textile-integrated systems for continuous, non-invasive health monitoring. This research introduces a novel method for fabricating highly stretchable, conductive microfibers through a wet-spinning process that incorporates carboxylated carbon nanotubes (CNTs) and Ti 3 C 2 T x MXene into a styrene-ethylene-butylene-styrene (SEBS) fiber matrix. By employing the synergistic effects between the one-dimensional (1D) CNTs and two-dimensional (2D) MXene, our approach significantly improves both mechanical robustness and sensitivity to deformation in the composite conductive network, effectively overcoming the limitations typically encountered in single-filler fibers. The SEBS/CNTs-Ti 3 C 2 T x composite fibers exhibit outstanding mechanical performance, with an elongation at break surpassing 1000 %, and are capable of enduring substantial strain without compromising electrical conductivity. These fibers maintain exceptional electromechanical stability and sensitivity across a wide range of strain conditions, ensuring reliable, real-time monitoring of human motion signals. Furthermore, a textile woven from these composite fibers shows impressive electromagnetic interference (EMI) shielding performance, achieving an effectiveness of 45.1 dB within the 8.2–12.8 GHz frequency range. This bi-functionality emphasizes the substantial potential of the SEBS/CNTs-Ti 3 C 2 T x composite fibers for both healthcare and smart textile industries.
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APPLIED SURFACE SCIENCE
·
2024
·
IF 6.3
Nuo Fu,Han Liu,Jingwen Zhang,Shuyu Wang,Yong Yang,Kunlin Chen,Ziwei Deng
Textile-based wearable electronic devices have gained significant attention due to their promising applications in personal thermal management, human healthcare monitoring, and human motion detection. Herein, a multifunctional MXene-decorated textile has been fabricated as a promising wearable electronic textile for thermal management, durable self-cleaning, bio-protection and wearable strain sensor. In this study, Ti 3 C 2 T x MXene nanosheets , which are followed by surface engineering with mussel-inspired polydopamine coatings and hydrophobic octadecyl trimethoxysilane, are chosen as active materials for constructing multifunctional MXene-decorated textile. Thus, the multifunctional MXene-decorated textile (Cotton@ODMX) is fabricated by spray-coating the hydrophobic MXene-based composites (ODMX) onto the surface of the cotton textile. Such a Cotton@ODMX epitomizes a highly innovative electronic textile that not only retains the flexibility of the original textile, but also possesses remarkable superhydrophobic properties, outstanding photothermal conversion performance, photothermal self-healing capabilities, environmental stability and exceptional photothermal sterilization capabilities. More importantly, Cotton@ODMX is demonstrated to serve as a wearable strain sensor to monitor fundamental human movements, thus highlighting its impressive sensing capabilities. This work offers valuable insights for the development of multifunctional, flexible and wearable electronic devices with promising potential in personal thermal management, human healthcare monitoring, and human motion detection.
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