SENSORS AND ACTUATORS B-CHEMICAL
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2024
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IF 8
Mimi Han,Wenhao Shen,Xin Tong,Jean-Pierre Corriou
Two-dimensional (2D) MXene provides large surface area for the adsorption and interaction of H 2 O molecules, which is highly desirable for the construction of humidity-sensing materials. However, the drawbacks, involving easy stacking and poor mechanical strength, pose a huge challenge to its practical application. Herein, inspired by nacred “brick-mortar” nanostructure , a nanopaper humidity sensor made of flexible TEMPO-oxidated cellulose nanofibers/MXene/silver nanowires (TOCNFs/MXene/AgNWs) was developed by vacuum-assisted filtration self-assembly strategy. The synergism of 1D TOCNFs, AgNWs “mortar” and 2D MXene “bricks” endows the nanopaper with superb tensile strength (146.3 MPa), modulus (16.9 GPa), and superior bending durability, and the obtained TOCNFs/MXene/AgNWs nanopaper humidity sensor exhibits high response value of 90% at 97% RH with a low MXene addition of 20 wt%. Furthermore, the unique photothermal response property of MXene accelerates the desorption of H 2 O molecules during sensor recovery, realizing the reversible sensing performance. The proposed humidity sensing mechanism lies in the variation of MXene interlayer d-spacing induced by adsorbing ambient H 2 O molecules and the swelling of TOCNFs. Lastly, the sensor demonstrates the possibilities in human respiration monitoring, non-contact sensing, and humidity actuating.
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ACS Applied Nano Materials
·
2025
·
IF 5.5
Zhaoxian Chen,Yao Liu,Wenrou Yu,Shihong Liu,Yingzhou Huang
Traditionally, cardiovascular disease diagnosis has relied on invasive testing methods, which may cause anxiety or discomfort in patients. Noninvasive diagnostic technologies, such as wearable sensors, offer significant advantages by reducing these concerns. Surface-enhanced Raman spectroscopy (SERS) is an ultrasensitive technique well-suited for disease diagnosis, particularly when combined with machine learning (ML) algorithms. In this study, we introduce AgNW/MXene hydroxyl composite membranes as SERS substrates for cholesterol detection in sweat. The high specific surface area of MXene enhances the adsorption of target molecules, thereby improving SERS signal sensitivity. Cholesterol was successfully detected at a concentration of 10–8 M, demonstrating the robustness of the method over 50 stretch-release cycles. A random forest (RF) model was employed to classify sweat samples from healthy individuals and cardiovascular patients, achieving an accuracy of 83.5%. Compared to traditional invasive methods, our approach provides a noninvasive, highly sensitive, and durable alternative with the added advantage of easy integration into wearable diagnostic devices. The high sensitivity and durability of these wearable sweat sensors highlights their potential for advancing noninvasive cardiovascular disease detection.
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CARBOHYDRATE POLYMERS
·
2024
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IF 10.7
Yangkai Xiong,Zhiqiang Fang,Panpan Tang,Yu Li,Hao Jiang,Jipeng Li,Zheng Li,Guoqing Wang
Biological fouling is a considerable threat to the marine industry because attached microcontaminants and microorganisms inflict serious damage on marine installations and aquacultures. Although there has been tremendous effort in researching marine antifouling, it is yet challenging to develop a long-term and consistent antifouling strategy and materials. Here, polyhexamethylene-biguanide (PHMB) and MXene are introduced into the carboxylated cellulose nanofibers (CNF) reinforced polyvinyl alcohol (PVA) hydrogel to obtain a self-healing and ultra-high toughness antifouling hydrogel. The as-prepared double network (DN) hydrogels have extremely high toughness (16,050 kJ/m 3 ), superior anti-protein adhesion (100 %) and anti-algal adhesion (100 %), exceptional antibacterial activity (99.97 %), and remarkable photothermal self-healing capability. Furthermore, the DN hydrogel provide outstanding antifouling performance for at least six months in the actual marine field. This work provides an effective and feasible strategy to prevent marine biofouling and also initiates new approaches to the application of hydrogel.
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CEMENT & CONCRETE COMPOSITES
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2024
·
IF 10.8
Zhichao Xu,Hui Yu,Huayang Sun,Yingzi Yang
The aim of this study was to modify strain hardening cementitious composite (SHCC) using MXene nanosheets to further enhance its strength and ductility. The results showed that the addition of 0.03 wt% MXene nanosheets increased the compressive strength and tensile strain of SHCC by 18.04 % and 88.18 %, respectively. The mechanism of MXene nanosheets in improving the mechanical properties of SHCC was revealed by single fiber pullout test, micromechanical analysis, microstructure analysis and finite element analysis. Firstly, MXene nanosheets fill the pores inside the matrix, reduce the porosity of the matrix, disperse the stress, and inhibit the crack propagation, thus improving the compressive properties of SHCC. Secondly, when MXene nanosheets adhered to the fiber surface, they modified the interfacial properties between the fiber and the matrix, preventing fiber pullout and consequently improving the tensile ductility of SHCC.
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JOURNAL OF MEMBRANE SCIENCE
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2024
·
IF 8.4
Yaqi Zhang,Shiwei Tian,Qiankun Sha,Kangli Ding,Xuhuan Yan,Xingxiang Zhang,Na Han
Covalent organic frameworks (COFs) have evolved into a transformative category of nanofiltration materials due to their intrinsic pore channels and high porosity, sparking a burgeoning interest in fully harnessing the potential of COFs for applications in nanofiltration . Herein, a sandwich structured MXene/COFs membrane was fabricated by the technique of layer-by-layer electrophoretic deposition (LBL EPD), with COFs nanospheres (COFs NPs) serving as the intermediate layer. During the EPD process , controlling the deposition time allows for convenient regulation of each layer's thickness, enabling rapid production of defect-free MXene/COFs membranes. The ultra-thin MXene layer offers excellent film-forming properties for COFs NPs, whereas the intermediate layer of COFs NPs plays a primary sieving function. Moreover, the pore-rich COFs NPs, the ultra-thin MXene layer, and the COFs NPs layer with abundant slits guarantee short and successive mass transport pathways. Under optimal conditions, the MXene/COFs membrane provided a permeance as high as 200.2 L‧m −2 ‧h −1 ‧bar −1 and a rejection rate of Congo red (CR) as high as 98.9 %. This exceptional performance holds steadfast even within pH ranges of 7–11 and during long-term operation. Meanwhile, MXene/COFs membranes exhibit commendable salt/dye separation performance, achieving an excellent separation factor of 121.1 for NaCl/CR. Moreover, the membrane's exceptional robustness and mechanical strength further facilitate its stable utilization under high transmembrane pressure (1–5 bar). To summarize, MXene/COFs membranes, characterized by their excellent nanofiltration and salt/dye separation performance, highlight the advantages of COFs within the nanofiltration field. This study introduces an innovative alternative approach to designing COFs membranes for highly efficient and high-precision molecular separations.
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INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
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2025
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IF 8.5
Lingli Zheng,Yue Yang,Huayan Zhang,Tao Liao,Yingying Han,Miao Yu
Developing a compressible, ultralight, conductive, and hydrophobic biomass-based aerogel with multifunctional characteristics is greatly desirable nowadays. Herein, cellulose nanofiber (CNF)/Ti 3 C 2 T x (MXene)/polyvinyl alcohol (PVA) composite aerogels have been designed via a facile bidirectional freezing process, followed by chemical vapor deposition treatment. Benefiting from the porous architecture, chemical crosslinking and hydrogen-bonding between CNF, PVA and MXene, the aerogels exhibited oriented lamellar texture, endowing it with ultralow density, excellent compressibility, conductivity and recoverability. The polysiloxane coating imparted the aerogels outstanding hydrophobicity, contributing to an excellent capability for organic contaminants (e.g. N-hexane, cyclohexane, dichloromethane, chloroform, acetone, pump oil and edible oil) from water, including high adsorption capacity (30.43 to 167.00 g g −1 ) and stable recyclability. Utilized as pressure sensors, these aerogels showed excellent sensing properties, including high sensitivity (2.41 kPa −1 ), rapid response time (78 ms) and recovery time (83 ms), as well as exceptional detection ability for different human body movement information. It is expected that the fabricated composite aerogels will provide a new versatile platform for pressure signals detection and high-efficient organic contaminants adsorption.
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CHEMICAL ENGINEERING JOURNAL
·
2025
·
IF 13.2
Fuming Wang,Xiaodong Zhu,Qianwen Zhang,Minghui Xie,Lei He,Jiahao Guo,Ang Li,Qingsong Yang,Jijin Yang,Wei Li
Cryoablation (CRA) is a clinical treatment modality for minimally invasive local tumor ablation. Rare clinical reports have shown that CRA can induce a cryoimmune effect and enhance systemic anti-tumor immunity against potential metastases, a phenomenon known as the “abscopal effect”. Here, we innovatively propose a sequential treatment strategy to improve the tumor immune microenvironment by activating the cGAS-STING signaling pathway of immune cells and mild photothermal therapy (mPTT) before CRA, making this rare but exciting phenomenon more reproducible. Specifically, we designed functional nanosheets (Ti 3 C 2 @Au-PEG-DMXAA) based on Ti 3 C 2 MXene, with gold nanoparticles attached to the surface, PEGylated, and loaded with the STING agonist (DMXAA). Due to the attachment of gold nanoparticles, CT-guided visual injection of the functional nanosheets was achieved. The synergistic effect of mPTT and STING pathway activation promoted the immunogenic death of tumor cells, activation of dendritic cells, repolarization of tumor-associated macrophages, and enrichment of cytotoxic T cells in the tumor microenvironment. Subsequently, sequential CRA eradicated local “hot” tumors, initiating a “cancer vaccines” effect through the in-situ gradual release of tumor-associated antigens, boosting systemic anti-tumor immunity, and effectively generating long-term immune memory, thereby inhibiting tumor recurrence and distant metastases.
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MICROCHEMICAL JOURNAL
·
2025
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IF 5.1
Xuan Weng,Guanbo Wang,Hang Zhang,Hai Jiang
This study presents a titanium carbide MXene–gold nanocomposites (MXene–AuNCs)-based aptasensor for the sensitive detection of neuron-specific enolase (NSE). Laser-induced graphene electrodes (LIGEs) were fabricated using polyimide film as the three-electrode electrochemical sensing system. Specifically, MXene–AuNCs were immobilized on the working electrode to enhance both the electronic conduction and the immobilization capacity of the NSE aptamers (Apt). As a labeling material, MXene–AuNCs–Apt facilitated signal amplification, enabling highly sensitive detection. Under optimized conditions, this aptasensor exhibited an ultralow detection limit of 0.13 pg/mL for NSE, a wide detection range from 0.01 ng/mL to 100 ng/mL along with satisfactory reproducibility, repeatability, specificity and stability. Furthermore, the proposed aptasensor was successfully applied to measure NSE levels in serum samples. This work provides an efficient strategy for the fabrication of high-performance electrochemical biosensors in the preliminary estimates and diagnosis of lung cancer at early stages.
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JOURNAL OF NANOBIOTECHNOLOGY
·
2025
·Vol. 23
·期 1
·1-17
·
IF 12.6
Zhu Huan,Zhang Zhaoyuan,Jiang Rong,Xu Liangfu,Yang Xiangdi,Chen Jie,Wang Zhenning,Xu Xiao,Liu Zhigang
Radiotherapy (RT) effectiveness is limited by low DNA damage in tumor cells, surrounding tissue harm, and tumor radioresistance with active DNA repair. Herein, we have engineered a two-dimensional nanomaterial consisting of MXene nanosheets at its core, coated with gold nanorods and a cisplatin shell, and further modified with polyvinyl alcohol, referred to as APMP. The APMP exploits its distinctive electronic properties and photothermal effects to augment radiosensitivity and impede DNA damage repair mechanisms. In vitro experiments demonstrate that APMP elevates reactive oxygen species (ROS) production to approximately 2.6 times higher than that achieved with radiotherapy alone, thereby significantly enhancing the sensitivity to radiotherapy. Combining APMP with photothermal therapy (PTT) and RT is a promising glioblastoma treatment strategy, achieving tumor destruction via localized hyperthermia and overcoming radioresistance. This approach achieves precise tumor targeting, reducing side effects and enhancing therapeutic response in preclinical models. The novel core-shell design enables potent radiotherapy-specific radiosensitizers that drive immunogenic cell death, enhancing glioblastoma combination immunotherapy. This universal strategy heralds a new era in integrating radiotherapy sensitizers with immunotherapy. Graphical
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Materials Today Physics
·
2024
·
IF 10
Hongyan Yin,Lizhi Chen,Fangfei Liu,Tursun Abdiryim,Jiaying Chen,Xinyu Jing,Yancai Li,Mengyao Su,Xiong Liu
MXene-based conductive hydrogels have emerged as a new type of soft materials in flexible electronics. Herein, metal coordination is introduced into MXene-based conductive hydrogels to synchronously enhance the mechanical and self-healing properties. MXene-based conductive hydrogels are made up of polyacrylic acid (PAA), sium carboxymethyl cellulose (SCMC), Ti 3 C 2 T X and metal ions (Ni 2+ , Al 3+ or Sn 4+ ). PAA/SCMC/Ti 3 C 2 T X /Sn 4+ hydrogel is found to have excellent mechanical (stress: 122 kPa; strain: 1688 %; toughness: 0.95 ± 0.12 MJ m −3 ) and self-healing (self-healing efficiency: 99.27 % (conductivity); 81.16 % (stress); and 83.13 % (strain)) properties due to the metal coordination and H-bonding. The hydrogel has also good conductivity of 0.82 S m −1 and adhesion of 38.94 kPa. The flexible sensors based on this hydrogel can efficiently detect human motions, electromyography (EMG), electrocardiography (ECG) and handwriting signals. Furthermore, a supercapacitor assembled from this hydrogel has a high specific capacitance of 118.66 F g −1 and good stability (15000 charge-discharge cycles). This work provides an effective strategy for exploiting mechanically tough and self-healing MXene-based conductive hydrogels with prospective applications in flexible electronics.
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INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2024
·
IF 7.7
Yixuan Wu,Qingqing Yu,Xuyue Zhou,Weixiao Ding,Xinmeng Li,Peng Zhou,Yalei Qiao,Zhen Huang,Shujun Wang,Jiaan Zhang,Luyu Yang,Lei Zhang,Dongping Sun
Electrical stimulation therapy is effective in promoting wound healing by rescuing the decreased endogenous electrical field, where self-powered and miniaturized devices such as nanogenerators become the emerging trends. While high-voltage and unidirectional electric field may pose thermal effect and damage to the skin, nanogenerators with lower voltages, pulsed or bidirectional currents, and less invasive electrodes are preferred. Herein, we construct a polydopamine (PDA)-modified poly-L-lactic acid (PLLA) /MXene (PDMP/MXene) nanofibrous composite membrane that generates piezoelectric voltages matching the transepithelial potential (TEP) to accelerate wound healing. PDA coating not only enhances the piezoelectricity of PLLA by dipole attraction and alignment, but also increases its hydrophilicity and facilitates subsequent MXene adhesion for electrical conductivity and stability in physiological environment. When applied as wound dressings in mice, the PDMP/MXene membranes act as a nanogenerators with reduced internal resistances and satisfactory piezoelectric performances that resemble bioelectric potentials (~10 mV) responding to physical activities. The membrane significantly accelerates wound closure by facilitating fibroblast migration, collagen deposition and angiogenesis, and suppressing the expression of inflammatory responses. This piezoelectric fibrous membrane therefore provides a convenient solution for speeding up wound healing by sustained low voltage mimicking bioelectricity, better cell affinity.
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JOURNAL OF POWER SOURCES
·
2024
·
IF 8.1
Shaolin Yang,Panpan Fu,Zexi Chen,Ya Chen,Yajuan Feng,Jiandong Wu,Hui Lu,Chunping Hou
MXene exhibits significant promise as a cathode material for zinc-ion hybrid supercapacitors (ZHSCs) because of its remarkable physicochemical characteristics. However, the self-stacking and aggregation of two-dimensional MXene nanosheets limits the performance of ZHSCs. In this paper, MXene-reduced graphene oxide (rGO) heterostructures are prepared by a one-step method as binder-free cathode materials for ZHSCs. The integration of rGO nanosheets within MXene layers efficiently mitigates the self-stacking tendency of MXene nanosheets and widens their interlayer spacing, significantly enhancing ionic accessibility and facilitating ion transport within the structure. As a cathode material for ZHSCs, the MXene-rGO heterostructure exhibits remarkable electrochemical performance. The MXene-rGO cathode achieves a specific capacitance of up to 660 F g −1 at 0.5 A g −1 , and demonstrates an energy density of 86.4 Wh kg −1 at a power density of 222.3 W kg −1 , surpassing the majority of MXene-based cathodes previously documented for ZHSCs. The cathode also exhibits excellent cyclability with maintaining a capacity retention of 87.7 % after 10,000 cycles. The ease of production and outstanding performance of the MXene-rGO heterostructure suggests its potential as a highly promising cathode material for practical applications in ZHSCs.
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