JOURNAL OF SURFACTANTS AND DETERGENTS
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2017
·Vol. 20
·期 5
·1121-1127
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IF 1.45
Chen Xuewei,Xin Yujuan,Yu Fangcai,Lan Zhili
A series of carboxylic ester-containing imidazolium-based zwitterionic surfactants, namely, monoalkyl 2-(3-methylimidazolium-1-yl) succinate inner salts (C n MimSU, n = 8, 10, 12 and 14), have been synthesized. Their structures were confirmed by 1 H NMR, 13 C NMR and FTIR. The typical physicochemical properties parameters such as isoelectric point, critical micelle concentration (CMC), surface tension at CMC ( γ
CMC ), surface pressure at CMC (Π CMC ), adsorption efficiency (p C
20 ), the maximum surface excess ( Γ
m ), the minimum molecular cross-sectional area ( A
min ) and the value of CMC/ C
20 were determined. The effect of the long-chain length on the important physicochemical properties of C n MimSU was studied. It is found that the surface activity of C n MimSU is enhanced with the long-chain length increases.
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JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES
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2017
·
IF 2.603
Hongjuan Li,Ying Liu,Yuetao Yi,Qin miao,Sujing Liu,Feng Zhao,Wei Cong,Chunhua Wang,Chuanhai Xia
In China, Poacynum hendersonii is frequently used as a substitute for Apoacynum venetum L (Luobuma), which is a famous traditional Chinese medicine. Quercetin-3- O -sophoroside and isoquercitrin are two major flavonoids in Poacynum hendersonii leaves. In this work, a suitable method was established for the large-scale preparation of quercetin-3- O -sophoroside (QOS) and isoquercitrin (ISO) from Poacynum hendersonii leaves using macroporous resin combined with Sephadex LH-20 column chromatography. The adsorption/desorption capacities and desorption ratios of six macroporous resins were evaluated using static experiments. The HPD-300 resin had the best adsorption performance because it had the largest surface area, and was selected for further study. Compared with pseudo-first-order and intraparticle diffusion kinetics models, the pseudo-second-order model could better fit the adsorption kinetics of both QOS and ISO on the HPD-300 resin. In addition, the adsorption isotherms of the two compounds on the HPD-300 resin were fitted well to the Langmuir model. Under optimal conditions, the purities of QOS and ISO in the product were increased from 2.16% and 1.26% to 21.34% and 10.70% with recovery yields of 82.1% and 77.3%, respectively. Subsequently, Sephadex LH-20 column chromatography was employed for improving the purities of the two compounds. After separation by Sephadex LH-20 column chromatography, the purities of QOS and ISO achieved 93.5% and 95.6%, respectively.
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PubMed
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DYES AND PIGMENTS
·
2016
·
IF 4.055
Ling-Yu Dong,Li-Yun Wang,Xiang-Fang Wang,Yuan Liu,Hai-Ling Liu,Meng-Xia Xie
An environmental friendly fluorescence resonance energy transfer probe for determination of glucose has been developed. The natural pigment, 3-hydroxyflavone, can enter the hydrophobic cavity of beta-cyclodextrin functionalized ZnS quantum dots , forming a fluorescence resonance energy transfer system with beta-cyclodextrin modified ZnS quantum dots as energy donor and 3-hydroxyflavone as energy acceptors. Glucose can be oxidized with assistance of the glucose oxidase to quantitatively produce hydrogen peroxide, which could rapidly quench the fluorescence intensity of the 3-hydroxyflavone in the probe by catalysis of horseradish peroxidase. The probe was successfully applied to determination of glucose in human serum and urine samples, and the results indicated that the average spiking recoveries of glucose ranged from 102 to 113%, with relative standard deviations below 15%. The developed approach were simple and possessed high sensitivity and selective for glucose, and this work provides a new clue for developing fluorescent probe .
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JOURNAL OF MEMBRANE SCIENCE
·
2016
·
IF 5.557
Shu Xiong,Jian Zuo,Yuan Gui Ma,Lifen Liu,Hao Wu,Yan Wang
In this work, novel thin film composite (TFC) forward osmosis (FO) membranes are developed via interfacial polymerization on the polyacrylonitrile (PAN) substrate, using an organic-inorganic hybrid compound – N-[3-(trimethoxysilyl) propyl] ethylenediamine (NPED) as the amine monomer to mix with m-phenylenediamine (MPD). The PAN substrate was modified with sodium hydroxide and optimized by varying the hydrolyzation time. With the incorporation of NPED in the selective layer, the formed TFC membrane exhibits better hydrophilicity, improved water flux and fouling resistance, and therefore superior membrane performance. By varying the NPED content in the aqueous phase, the surface properties and performance of TFC membranes are investigated with various characterizations. In addition, the anti-fouling properties of the TFC membranes with different NPED content in the aqueous monomer are also studied.
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JOURNAL OF SOLID STATE CHEMISTRY
·
2017
·
IF 2.299
Misganaw Alemu Zeleke,Dong-Hau Kuo,Osman Ahmed Zelekew,Albert Daniel Saragih
Ge-substituted Cu 2 Sn(S,Se) 3 bulks with Cu 2 (Sn 1- x Ge x )(S,Se) 3 formula at x = 0, 0.25, 0.50, 0.75, and 1.0 were synthesized by reactive liquid phase sintering , where the heating process was held at 200 °C for 20 min before reaching the sintering temperature of 600 °C for 30 min. In the presence of volatile Sb 2 S 3 sintering aid , the effects on densification , grain boundary, crystalline size, and electrical properties of Ge-substitution were investigated. Cu 2 (Sn 1- x Ge x )(S,Se) 3 showed p-type behavior for all x values. It was found that the mobility was increased sharply and carrier concentration was decreased rapidly as the x -value was increased. The electrical conductivities were found to be 14.0, 22.7, 36.8, 126, and 153 S/cm at x = 0, 0.25, 0.50, 0.75, and 1.0, respectively. X-ray diffraction (XRD) peaks were shifted to the higher angle and band gaps increased upon successive increasing of the Ge/[Ge+Sn] fraction being 1.19, 1.21, 1.22, 1.24, and 1.26 eV at x = 0, 0.25, 0.50, 0.75, and 1.0, respectively. The studies of Ge-x-CTSSe bulks were based on Ge Sn defects and supported by the data of morphological, structural, electrical, and optical properties .
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ACS Applied Materials & Interfaces
·
2013
·
IF 5.008
Qiao An,Chuanyu Sun,Dian Li,Ke Xu,Jia Guo,Changchun Wang
Ascorbic acid (AA) is capable of inhibiting cancer cell growth by perturbing the normal redox state of cells and causing toxic effects through the generation of abundant reactive-oxygen species (ROS). However, the clinical utility of AA at a tolerable dosage is plagued by a relatively low in vivo efficacy. This study describes the development of a peroxidase-like composite nanoparticle for use in an AA-mediated therapeutic strategy. On the basis of a high-throughput, one-pot solvothermal approach, Fe3O4@C nanoparticles (NPs) were synthesized and then modified with folic acid (FA) on the surface. Particular focus is concentrated on the assessment of peroxidase-like catalytic activity by a chromogenic reaction in the presence of H2O2. The carbon shell of Fe3O4@C NPs contains partially graphitized carbon and thus facilitates electron transfer in the catalytic decomposition of H2O2, leading to the production of highly reactive hydroxyl radicals. Along with magnetic responsiveness and receptor-binding specificity, the intrinsic peroxidase-like catalytic activity of Fe3O4@C-FA NPs pronouncedly promotes AA-induced oxidative stress in cancer cells and optimizes the ROS-mediated antineoplastic efficacy of exogenous AA. In vitro experiments using human prostate cancer PC-3 cells demonstrate that Fe3O4@C-FA NPs serve as a peroxidase mimic to create hydroxyl radicals from endogenous H2O2 that is yielded in response to exogenous AA via an oxidative stress process. The usage of a dual agent leads to the enhanced cytotoxicity of PC-3 cells, and, because of the synergistic effect of NPs, the administrated dosage of AA is reduced markedly. However, because normal cells (HEK 293T cells) appear to have a higher capacity to cope with additionally generated ROS than cancer cells, the NP–AA combination shows little damage in this case, proving that selective killing of cancer cells could be achieved owing to preferential accumulation of ROS in cancer cells. A possible ROS-mediated mechanism is discussed to elucidate the pharmaceutical profile of the NP–AA agent. In general, this foundational study reveals that the peroxidase-like nanomaterials are applicable for modulating oxidative stress for the selective treatment of cancer cells by generating a high level of endogenous ROS.
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Analytical Methods
·
2014
·Vol. 6
·期 12
·4446-4454
·
IF 1.938
ZhuanZhuan Shi,XiaoShuai Wu,LiXia Gao,YunLi Tian,Ling Yu
In the present study, a carbon paper electrode (CPE)/cells-in-paper/CPE sandwich device was developed for the in situ detection of small molecules produced from cells growing in paper 3 dimensional matrix. To demonstrate the real-time assay capability of the electrodes/cells-in-paper sandwich device, carbon nanotube/graphene/MnO2 nanocomposite was synthesized to functionalize the working electrode. Scanning electron microscopy, transmission electron microscope and X-ray photoelectron spectroscopy characterization proved that MnO2 nanoparticles were uniformly distributed on nanotube sidewalls and graphene sheets. The carbon nanotube/graphene/MnO2 nanocomposite functionalized electrode/cells-in-paper sandwich device showed specific response against hydrogen peroxide. The fully assembled device displayed a linear range up to 25 mM with a sensitivity of 6.25 μA mM−1 cm−2 and a detection limit of 6.7 μM hydrogen peroxide. In addition, in situ detection of hydrogen peroxide production from cells growing in matrigel impregnated paper was successfully demonstrated on the electrodes/cells-in-paper sandwich device, highlighting the potential application of this low-cost paper analytical device for cell biology studies.
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JOURNAL OF POLYMER SCIENCE PART A-POLYMER CHEMISTRY
·
2013
·Vol. 51
·期 13
·2939-2947
·
IF 3.543
Zong-Quan Wu,Cheng-Gang Qi,Na Liu,Ying Wang,Jun Yin,Yuan-Yuan Zhu,Long-Zhen Qiu,Hong-Bo Lu
In this article, the synthesis of a series of conjugated rod–rod block copolymers based on poly(3-hexylthiophene) (P3HT) and poly(phenyl isocyanide) (PPI) building blocks in a single pot is presented. Ni-catalyzed Grignard metathesis polymerization of 2,5-dibromo-3-hexylthiophene and subsequent addition of 4-isocyanobenzoyl-2-aminoisobutyric acid decyl ester in the presence of Ni(dppp)Cl 2 as a single catalyst afford P3HT- b -PPI with tunable molecular weights and compositions. In solid state, microphase separation occurred as differential scanning calorimetric analysis of P3HT- b -PPI revealed two glass transition temperatures. In solutions, the copolymers can self-assemble into spherical aggregates with P3HT core and PPI shell in tetrahydrofuran and exhibit amorphous state in CHCl 3 . However, atomic force microscopy revealed that the block copolymers self-assemble into nanofibrils on the substrate. These unique features warrant the resultant conjugated rod–rod copolymers' potential study in organic photovoltaic and other electronic devices. © 2013 Wiley Periodicals, Inc. J. Polym. Sci., Part A: Polym. Chem. 2013, 51, 2939–2947
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Catalysis Science & Technology
·
2014
·Vol. 4
·期 12
·4308-4312
·
IF 4.76
Ran Ma,Cheng-Bin Huang,An-Hua Liu,Xue-Dong Li,Liang-Nian He
An environmentally benign CO2/glycol reversible acidic system was developed for the iron(III)-catalyzed aerobic oxidative iodination of electron-rich aromatics without the need for any conventional acid additive or organic solvent. Notably, moderate to high isolated yields (up to 97%) of the aryl iodides were attained with comparable regioselectivity when ferric nitrate nonahydrate was used as the catalyst with molecular iodine under 1 MPa of CO2.
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INORGANICA CHIMICA ACTA
·
2014
·
IF 2.041
Yong-Peng Xu,Jie Qin,Shi-Min Sun,Tong-Tong Liu,Xiao-Lin Zhang,Shao-Song Qian,Hai-Liang Zhu
Three novel complexes, [Ni II (dpp) 2 (L) 2 ] ( 1 ), [Ni II (eda) 2 (L) 2 ] ( 2 ) and [Ni II (deda) 2 (L) 2 ] ( 3 ) (L = 3-pyridinyl-4-amino-5-mercapto-1,2,4-triazole, dpp = 1,3-diaminopropane, eda = ethanediamine, deda = N,N-dimethyl ethylenediamine), were synthesized by reacting 3-pyridinyl-4-amino-5-mercapto-1,2,4-triazole with diamines and nickel(II) salt. The complexes were structurally determined by single-crystal X-ray diffraction. The inhibitory activity was tested in vitro against jack bean urease. Molecular docking was investigated to insert complexes into the crystal structure of jack bean urease at the active site to determine the probable binding mode. The experimental values and docking simulation exhibited that complexes 1 , 2 , 3 had better inhibitory activity than the positive reference acetohydroxamic acid, showing IC 50 values of 48.16, 32.35 and 15.22 μM, respectively. These complexes exhibited inhibitory activities as potent urease inhibitor.
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RSC Advances
·
2015
·Vol. 5
·期 30
·23229-23238
·
IF 3.84
Tao Xiang,Ting Lu,Rui Wang,Cheng Wang,Shu-Dong Sun,Hong-Bo He,Chang-Sheng Zhao
In the present study, a new method to prepare stable antifouling and blood compatible membranes is developed, i.e., in situ post-crosslinking copolymerization. Firstly, 3-methacryloxypropyl trimethoxysilane (MTSi)-based zwitterionic copolymer was synthesized by in situ copolymerization in polyethersulfone (PES) solution and fabricated into membranes by a liquid–liquid phase separation technique. Then the membranes were treated by basic solutions to promote the crosslinking of the copolymer via the hydrolysis of the methoxy groups. The surface free energy of the poly(3-methacryloxypropyl trimethoxysilane) (PMTSi) modified membranes reduced from 55.29 to 43.91 nJ cm−2. For the poly(3-methacryloxypropyl trimethoxysilane-co-sulfobetaine methacrylate) (P(MTSi-co-SBMA)) modified membranes, the hydrolyzed PMTSi segments were used as the crosslinker to make the membrane stable. Both the PMTSi and P(MTSi-co-SBMA) modified membranes showed improved antifouling property and blood compatibility (lowered protein adsorption amount, suppressed platelet adhesion and prolonged clotting time) compared with the pristine PES membrane. Thus the modified membranes provided wide choice for specific biomedical applications.
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JOURNAL OF COORDINATION CHEMISTRY
·
2015
·
IF 2.012
Cui-Cui Wang,Jin-Hua Wang,Gui-Mei Tang,Yong-Tao Wang,Yue-Zhi Cui,Seik Weng Ng
Three new metal coordination polymers constructed from adipic acid and 2-(pyridin-3-yl)-(1H)-benzimidazole ligands, [M(ADP)(3PBI)2(H2O)2]·2H2O (M = Ni and Co for 1 and 2, respectively) and [Cd(ADP)(3PBI)(H2O)] (3) [ADP = adipic acid dianion; 3PBI = 2-(pyridin-3-yl)-(1H)-benzimidazole], have been synthesized by hydrothermal reactions and were characterized by X-ray single-crystal diffraction, elemental analyses, IR, powder X-ray diffraction, and thermogravimetry. Complexes 1 and 2 are isostructural. Both form a 1-D linear chain structure, which is further assembled into a 3-D supramolecular framework by π⋯π stacking and hydrogen bonding interactions. Complex 3 possesses a binuclear unit and displays a 2-D layer which is further extended to a 3-D supramolecular architecture via hydrogen bonding and other weak packing interactions. The luminescent properties of 3 were investigated in the solid state at room temperature.
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