Chemistry-An Asian Journal
·
2015
·Vol. 10
·期 11
·2503-2511
·
IF 4.587
Chao Qi,Ying-Jie Zhu,Tuan-Wei Sun,Jin Wu,Feng Chen
Graphical Amorphous calcium phosphate mesoporous microspheres (ACP-MSs) have been synthesized using adenosine 5′-diphosphate disodium salt as an organic phosphorus source by a rapid microwave-assisted hydrothermal method. The ACP-MSs drug delivery system shows a pH-responsive drug release behavior and a high ability to damage cancer cells after loading doxorubicin. Herein we report a rapid and green strategy for the preparation of amorphous calcium phosphate mesoporous microspheres (ACP-MSs) using adenosine 5′-diphosphate disodium salt (ADP) as an organic phosphorus source by a microwave-assisted hydrothermal method. The effects of the pH value, the reaction time, and temperature on the crystal phase and morphology of the product are investigated. The ADP biomolecules used in this strategy play an important role in the formation of ACP-MSs. The as-prepared ACP-MSs are efficient for anticancer drug delivery by using doxorubicin (Dox) as a model drug, and the Dox-loaded ACP-MSs show a high ability to damage cancer cells. Moreover, the ACP-MSs drug delivery system exhibits a pH-responsive drug-release behavior due to the degradation of ACP-MSs at a low pH value, thus, it is promising for applications in pH-responsive drug delivery.
✓ 已验证
DOI
高影响因子
TALANTA
·
2019
·
IF 4.916
Lifen Cai,Xiangying Sun,Wei He,Ruolan Hu,Bin Liu,Jiangshan Shen
In this paper, a tetrahydro[5]helicene-based imide dye with thienyl group (THID) was studied on its solvatochromism and aggregation-induced emission (AIE) properties by dissolved in various organic solvents. The linear relationship between Stokes shift and aprotic solvent polarity parameter was well fitted with Lippert-Mataga model. Furthermore, Stokes shift also were positively correlated with the normalized molar electronic transition energy, suggested that THID exceptionally depends on solvent polarity for twisted intramolecular charge transfer. In addition, THID demonstrated typical AIE features when adding large amounts of water into good solvent. Meanwhile, it can function as intensity and wavelength-based fluorescence sensor for detecting low-level water content in water soluble solvents , even the low of detection was 0.014 vol% in ACN . Therefore, a simple and highly selective fluorescence analysis for glyceryl monostearate has been established on basis of its AIE property.
✓ 已验证
DOI
高影响因子
ACS Sustainable Chemistry & Engineering
·
2017
·
IF 5.951
Jia Ding,Pengjing Chen,Songyu Fan,Zhiqiang Zhang,Lupeng Han,Guofeng Zhao,Ye Liu,Yong Lu
Free-standing stainless-steel (SS)-fiber@meso-HZSM-5 core–shell catalysts engineered from micro- to macro-scale were highly efficiently synthesized via cost-effective steam-assisted crystallization (SAC) method. Impact of synthesis conditions on their morphology and textural/acidic properties was investigated by means of XRD, SEM, TEM, solid-state NMR, NH3-TPD, Py-IR and N2 physisorption. Single-run lifetime of such structured catalysts for MTP process was strongly dependent on their preparation conditions but slightly the product distribution. A volcano-like relationship for lifetime was observed against the SAC time, which was correlated well with the crystallization-time-dependent crystallinity, mesoporosity and crystal size. The promising SS-fiber@meso-HZSM-5 was the one obtained after the SAC for 12 h, which delivered a prolonged single-run lifetime of 620 h with a high propylene selectivity of ∼42% at 450 °C using a methanol weight hourly space velocity (WHSV) of 1 h–1, as the result of high crystallinity, well-developed mesoporosity and small crystal size. Note that well-developed mesoporosity was paramount for the catalyst stability improvement, because of enhanced accommodation capacity of zeolite shell for receiving formed coke.
✓ 已验证
DOI
高影响因子
Materials
·
2024
·Vol. 17
·期 6
·1440
·
IF 3.1
Yarong Bai,Chuhan Miao,Weilong Ouyang,Lang Wang,Haiqiang Wang,Zhongbiao Wu
Barium and iridium supported on Zeolite Socony Mobil-5 (ZSM-5) are efficient catalysts for the selective catalytic reduction of nitric oxide by carbon monoxide (CO-SCR), with enhanced cyclic stability. The introduction of Ba hindered the oxidation of metallic Ir active species and enabled Ir to maintain an active metallic state, thereby preventing a decrease in catalytic activity in the CO-SCR reaction. Moreover, the Ba modification increased the NO adsorption of the catalyst, further improving the catalytic activity. Owing to the better anti-oxidation ability of Ir0in IrBa0.2/ZSM-5(27) than in Ir/ZSM-5(27), IrBa0.2/ZSM-5(27) showed better stability than Ir/ZSM-5(27). Considering that all samples in the present study were tested to simulate actual flue gases (such as sintering flue gas and coke oven flue gas), NH3was introduced into the reaction system to serve as an extra reductant for NOx. The NOxconversion to N2(77.1%) was substantially improved using the NH3-CO-SCR system. The proposed catalysts and reaction systems are promising alternatives for treating flue gas, which contains considerable amounts of NOxand CO in oxygen-enriched environments.
✓ 已验证
DOI
PubMed
高影响因子
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
·
2019
·
IF 3.131
Feng Gao,Xinlei Wu,Die Wu,Jianxing Yu,Jun Yao,Qi Qi,Zhihai Cao,Qinmin Cui,Yifang Mi
This work reports the synthesis of novel degradable magnetic temperature- and redox-responsive polymer/Fe 3 O 4 nanocomposite nanogels (NCGs) through inverse miniemulsion polymerization and their potential application as nanocarriers for controlled drug delivery. Surface of Fe 3 O 4 magnetic nanoparticles (MNPs) were vinyl-modified with 2-isocyanatoethyl methacrylate . Poly( N -vinylcaprolactam) (PNVCL)/Fe 3 O 4 NCGs were prepared via inverse miniemulsion polymerization by using a disulfide-containing cross-linker. The Fe 3 O 4 MNPs were chemically attached to the polymer matrix of NCGs, offering a good structural integrity of NCGs in aqueous systems. The PNVCL/Fe 3 O 4 NCGs not only inherited the good superparamagnetism of Fe 3 O 4 MNPs, but also displayed a reversible temperature-responsiveness as well as marked redox-responsiveness. The release behavior of a model anticancer drug 5-fluorouracil from the PNVCL/Fe 3 O 4 NCGs could be conveniently tuned by the external temperature, redox condition of media, or their combination. The prepared PNVCL/Fe 3 O 4 NCGs displayed a low cytotoxicity, holding a great potential in functioning as magnetic guiding nanocarriers for controlled drug delivery.
✓ 已验证
DOI
高影响因子
Royal Society Open Science
·
2018
·Vol. 5
·期 4
·
IF 2.504
Donglin He,Huiping Zhang,Ying Yan
Cu-ZSM-5 catalysts were prepared by chemical vapour deposition for catalytic wet peroxide oxidation (CWPO) of phenol in a fixed bed reactor. Firstly, Cu-ZSM-5 catalysts with Cu loading of 0.5, 2, and 6 wt% were prepared and characterized by X-ray diffraction (XRD), N2 adsorption–desorption and X-ray photoelectron spectra (XPS). The characterization results demonstrated that CuO was uniformly dispersed on ZSM-5 with slight effect on the structure properties of the support. Then, several variables, such as the copper loading, reaction temperature, catalyst bed height and feed flow rate were investigated in the CWPO of phenol in aqueous solution at high concentration (1000 ppm). Compared with the catalyst prepared by the impregnation method, the Cu-ZSM-5 prepared by chemical vapour deposition has a better capacity of further oxidizing the intermediate organic products into carbon dioxide and water with less metal loading. Based on the Cu-ZSM-5 catalyst with Cu loading of 6 wt%, complete removal of phenol and a high TOC reduction (around 70%) have been achieved at the temperature of 80°C feed flow rate of 2 ml min−1 and catalyst bed height of 3 cm. Moreover, this catalyst maintained high catalytic activity after three runs with high phenol conversion (94%) under this optimum operating condition. Finally, the reaction mechanism was studied based on the intermediates detected by high-performance liquid chromatography (HPLC).
✓ 已验证
DOI
高影响因子
INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH
·
2022
·
IF 4.326
Jun Xiao,Mengmeng Wang,Yaru Wang,Xunxun Li,Jiaqin He,Yunchong Liu,Qingfeng Xu,Hua Li,Najun Li,Dongyun Chen,Jianmei Lu
Catalytic oxidation is one of the most promising methods to remove toluene; manganese-cerium catalysts have high activity in the catalytic oxidation of toluene. Herein, nano-sized ZSM-5 was synthesized using a simple hydrothermal method, and catalysts with different Mn and Ce contents were prepared via alcohol-induced redox precipitation at room temperature. In addition, zeolite provides sufficient surface area for the dispersion of manganese cerium catalysts and plays a role in concentration and enrichment in the catalytic conversion of toluene. Based on the experimental characterization results, the 20Ce/M1Z1 catalyst exhibited the best catalytic activity, achieving 90% toluene conversion at 215 °C. Moreover, the catalyst still has excellent catalytic activity in humid environments. This work provides a new strategy to expose more active sites and enhance toluene adsorption, which provides a reference for the development of more efficient catalysts in the future.
✓ 已验证
DOI
高影响因子
JOURNAL OF CHEMICAL AND ENGINEERING DATA
·
2022
·
IF 3.119
Mengyang Guo,Ye Jiang,Yonghong Li,Yanyu Wei,Hanxi Li
The isobaric vapor–liquid equilibria (VLE) of two binary mixtures (adiponitrile + 2-methylglutaronitrile and adiponitrile + trans-3-pentenenitrile) at 5 and 10 kPa were measured using a modified Rose–Williams still. The thermodynamic consistency of the VLE data was tested by the Wisniak method and the Fredenslund method. The isobaric VLE data were correlated with four activity coefficient models of Margules, van Laar, Wilson, and NRTL, and the parameters of the models were obtained by the ordinary least-squares method. The isobaric VLE data were compared with the original UNIFAC predictive model. Furthermore, the excess Gibbs free energy of studied mixtures was determined. The RMST and RMSy1 were determined to evaluate the regression results. The results show that the Wilson model has a better correlation effect than other models.
✓ 已验证
DOI
高影响因子
JOURNAL OF PHYSICAL CHEMISTRY B
·
2018
·
IF 3.146
Xueli Wang,Zhongneng Zhou,Yuankai Tang,Jinquan Chen,Dongping Zhong,Jianhua Xu
Methylated
cytosine is proved to have an important role as an epigenetic
signal in gene regulation and is often referred to “the fifth
base of DNA”. A comprehensive understanding of the electronic
excited state relaxation in cytosine and its methylated derivatives
is crucial for revealing UV-induced photodamage to the biological
genome. Because of the existence of multiple closely lying “bright”
and “dark” excited states, the decay pathways in these
DNA nucleosides are the most complex and the least understood so far.
In this study, femtosecond transient absorption with different excitation
wavelengths (240–296 nm) was used to study the relaxation of
excited electronic states of 5-methylcytosine (5mC) and 2′-deoxy-5-methylcytidine
(5mdCyd) in phosphate buffered aqueous solution and in acetonitrile
solution. Two distinct nonradiative decay channels were directly observed.
The first one is a several picosecond internal conversion channel
that involves two bright ππ* states (ππ*2 and ππ*1) when ππ*2 state is initially populated. The second channel contains
the lower energy ππ*1 state and a so far experimental
unidentified long-lived state which exhibits a several nanosecond
lifetime. The long-lived state can only be accessed by the initially
excited ππ*1 state. Inspired by this new discovery
in 5mC and 5mdCyd, we revisited the decay of excited state of 2′-deoxycytidine
(dCyd), revealing very similar decay pathways. Additionally, a well-known
dark nOπ* state (carbonyl lone pair) with ∼30
ps lifetime is present in both decay channels in dCyd. With our detailed
experimental results, we successfully reconcile the long history debate
of cytosine excited state relaxation mechanism by pointing out that
the reason for the complex dynamics under traditional 266 nm excitation
is mixed signals from the above-mentioned two distinct decay pathways.
Our findings lead to a dramatically different and new picture of electronic
energy relaxation in 5mdCyd/dCyd and could help to understand photostability
as well as UV-induced photodamage of these nucleotides and related
DNAs.
✓ 已验证
DOI
高影响因子
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
·
2024
·Vol. 31
·期 17
·25114-25128
·
IF 0
Qi Qi,Wang Zhuang
Assessment and prediction for the ecotoxicity of engineered nanoparticles (ENPs) at the community or ecosystem levels represents a critical step toward a comprehensive understanding of the ecological risks of ENPs. Current studies on predicting the ecotoxicity of ENPs primarily focus on the cellular and individual levels, with limited exploration at the community or ecosystem levels. Herein, we present the first of the reports for the direct prediction of aquatic ecological risk for ENPs at the community level using machine learning (ML) approaches in the field of computational toxicology. Specifically, we extensively collected the threshold concentrations of twelve ENPs including metal- and carbon-based nanoparticles for aquatic species, i.e., hazardous concentrations at which 5% of species are harmed (HC 5 ), established by a species sensitivity distribution. Afterwards, we used eight supervised ML methods including Adaboost, artificial neural network, C4.5 decision tree, K-nearest neighbor, logistic regression, Naive Bayes, random forest, and support vector machine to develop nine classification models and four regression models, respectively, for the qualitative and quantitative prediction of HC 5 . The evaluation of model performance yielded the internal validation accuracy of all classification models ranging from 71.4 to 100%, and the determination coefficient of regression models ranging from 0.702 to 0.999, indicating that the developed models showed good performance. By using a cross-validation method and an application domain characterization, the selected models were further validated to have powerful predictive ability. Furthermore, the incorporation of three nanostructural descriptors (metal oxide sublimation enthalpy, zeta potential, and specific surface area) linked to toxicity mechanisms (the release of metal ions, the stability of dispersions of particles in aqueous suspensions, and the surface properties of the material) effectively enhanced the prediction power and mechanistic interpretability of the selected models. These findings would not only be beneficial in the screening of ENPs with potential high ecological risks that need to be tested as a priority but also contribute to the development of environmental regulations and standards for ENPs.
✓ 已验证
DOI
JOURNAL OF COLLOID AND INTERFACE SCIENCE
·
2025
·
IF 9.7
Nengcui Zhang,Yimin Zhang,Feng Wu,Ziyan Liu,Xinyu Xu,Qiang Li,Yi Mei,Yun Zu
Phosphorus (P)-doping H-ZSM-5 zeolites, which is crucial for industrial applications, aim to adjust both acidity and framework stability while optimizing product distribution in heterogeneous catalysis. Nonetheless, current phosphating methods often suffer from inadequate phosphorus dispersion and unclear interfacial interactions with framework aluminum (Al). In this work, P-doping ZSM-5 zeolites were successfully one-step prepared by using tributylphosphine served as an organophosphorus precursor, assisting by density functional theory calculations. On account of this, a stable interface of tetracoordinated-phosphorus and framework Al was fabricated uniformly. Such an interfacial structure not only made more framework Al sit in the straight/sinusoidal channels, but also remodeled Brønsted acid sites and reinforced its acidity. Under comparable conditions, methanol-to-propylene (MTP) evaluations indicated that the high-silica PZ-75 zeolite catalyst displayed an appreciable catalytic lifetime (30 h) and a higher C 3 H 6 selectivity (52.4 %). Additionally, in-situ Fourier transform infrared spectroscopy further revealed that this exceptional MTP performance was attributable to the predominant olefinic pathway and lower hydrogen transfer ability. These results provide valuable information for cognizing phosphorus-zeolite chemistry and creating high-performance MTP catalytic materials.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF ANALYTICAL AND APPLIED PYROLYSIS
·
2025
·
IF 6.2
Ke Yang,Gang Wu,Bo Zhang,Liangyuan Jia,Huiyan Zhang
Catalytic fast pyrolysis (CFP) is one of the most efficient methods for directly converting biomass into green aromatics. Although ZSM-5 catalyst is efficient at producing aromatics, the catalyst deactivation brings challenge to industrial applications. Constructing additional mesoporous structure in ZSM-5 catalyst can overcome this drawback. In this study, two solid wastes are used as raw materials to synthesize hierarchically porous ZSM-5 catalyst based on solvent-free method, aligning with the target of “green chemistry”. Comparing with the commercial ZSM-5 catalyst, the synthesized catalyst achieves a higher BTX yield (benzene, toluene, and xylene), with increases of approximately 44 %, 7 %, and 12 %, respectively. The mesopore-to-micropore volume ratio is a key factor in determining catalytic efficiency. Moreover, PI-MS is used to monitor the deactivation behavior of catalyst online during the CFP process, showing that the synthesized catalyst has a slower deactivation rate. The hierarchically porous structure plays a crucial role in slowing the transformation of oxygenated coke into graphite-like coke, which is a major contributor to catalyst deactivation. This work can provide a green and convenient method for producing hierarchically porous ZSM-5 catalyst and be useful for improving the selectivity of aromatic compounds, offering a promising alternative to conventional ZSM-5 catalyst in industrial applications.
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）