ANALYTICAL CHEMISTRY
·
2024
·
IF 6.7
Fan Chen,Jinhao Wang,Lijuan Chen,Haoliang Lin,Dongxue Han,Yu Bao,Wei Wang,Li Niu
Wearable, noninvasive sensors enable the continuous monitoring of metabolites in sweat and provide clinical information related to an individual’s health and disease states. Uric acid (UA) is a key indicator highly associated with gout, hyperuricaemia, hypertension, kidney disease, and Lesch–Nyhan syndrome. However, the detection of UA levels typically relies on invasive blood tests. Therefore, developing a wearable device for noninvasive monitoring of UA concentrations in sweat could facilitate real-time personalized disease prevention. Here, we introduce 1,3,6,8-pyrene tetrasulfonic acid sodium salt (PyTS) as a bifunctional molecule functionalized with Ti3C2Tx via π–π conjugation to design nonenzymatic wearable sensors for sensitive and selective detection of UA concentration in human sweat. PyTS@Ti3C2Tx provides many oxidation–reduction active groups to enhance the electrocatalytic ability of the UA oxidation reaction. The PyTS@Ti3C2Tx-based electrochemical sensor demonstrates highly sensitive detection of UA in the concentration range of 5 μM–100 μM, exhibiting a lower detection limit of 0.48 μM compared to the uricase-based sensor (0.84 μM). In volunteers, the PyTS@Ti3C2Tx-based wearable sensor is integrated with flexible microfluidic sweat sampling and wireless electronics to enable real-time monitoring of UA levels during aerobic exercise. Simultaneously, it allows for comparison of blood UA levels via a commercial UA analyzer. Herein, this study provides a promising electrocatalyst strategy for nonenzymatic electrochemical UA sensor, enabling noninvasive real-time monitoring of UA levels in human sweat and personalized disease prevention.
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CHEMICAL ENGINEERING JOURNAL
·
2024
·
IF 13.3
Biaobiao Yan,Xiaoting Liao,Tianlei Sun,Leilei Wu,Zhenfei Guo,Man Zhou,Yuanyuan Yu,Qiang Wang,Chaobin He,Ping Wang
Achieving multifunctional integration with comfortability and durability comparable to conventional textiles is one of the ultimate pursuits of personal protective wearables. Herein, a multi-protective textile with breathable, moisture-permeable and washable properties is reported, which is realized by cross-linking of electroactive MXene@gallic acid (MG) with the cationized cotton. Cationic modification reduces the charge repulsion between MG and cotton fibers, and promotes the deposition of conductive media on textile surface. After borax (STB) cross-linking, the obtained textile exhibits superior service stability and can be subjected to conventional washing, exhibiting antioxidant stability during natural storage. Importantly, the cross-linked textile inherits the properties of good breathability, softness and bendability as the original fabric. With the outstanding conductivity (260 mS/cm) and high absorptivity of the solar spectrum (0.920), the textile was used for Joule heating and solar heating, demonstrating their potential in the field of thermal management. Meanwhile, the textile demonstrates excellent antibacterial activity against Gram-negative Escherichia coli and Gram-positive Staphylococcus aureus , and maintained satisfactory antibacterial effect (>90 %) even after ten washing cycles. This facile strategy for fabricating personal protective textiles, based on cross-linking cotton fiber with electroactive mediators offers favorable durability, comfortability and multifunctionality, providing a scalable and sustainable approach for manufacturing multi-protective wearables.
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CHEMICAL ENGINEERING JOURNAL
·
2025
·
IF 13.2
Xiang-Dong Xu,Jing Li,Jun-Qi Zhang,Yuan Peng,Chen-Mei Sun,Ru-Qi Liang,Jian-Bo Qu
Conventional polysaccharide monoliths with irregular interstitial channels are suffering from low mechanical strength, specific surface areas, permeabilities and large eddy diffusion. In this work, the 3D bicontinuous MXene/agarose composite (BMAC) monoliths were facilely fabricated for the first time by a bicontinuous medium internal phase emulsion (MIPE) templating method. Poly (1-vinylimidazole) (PVIM) brushes were further grafted onto the 3D BMAC (BMAC@PVIM) monolith for highly selective enrichment of antibodies. Molecular docking simulation revealed that the adsorption mechanism of human immunoglobulin G (hIgG) on the monolith is primarily driven by multiple hydrogen bonding and hydrophobic interactions, and the optimal number of VIM units in the PVIM brush is determined to be 9. The resulting 3D BMAC@PVIM monolith exhibited a well-ordered structure, featuring a sturdy framework with diffusive mesopores (∼9 nm) and interconnected gigapores (∼10.1 μm). This composite monolith demonstrated a significantly higher specific surface area (46.6 m 2 /g), enhanced column permeability (1.67 × 10 −12 m 2 ), and increased operating flow rate (20 mL/min) compared to its counterpart (GMAC@PVIM monolith) prepared using the conventional MIPE template. Benefiting from its uniform and ordered skeleton and pore channels, the maximum equilibrium adsorption capacity of hIgG on the monolith could achieve 217.4 mg/g, which is superior to most reported separation materials. Meanwhile, the high adsorption rate constant in the film mass transfer stage also confirmed the satisfactory mass transfer efficiency of interconnected gigapores within the monolith. The 3D BMAC@PVIM monolith can efficiently purify antibodies with a purity of 94.1 % from human serum at a flow rate of 12 mL/min, demonstrating great potential in the field of rapid antibody purification.
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Gels
·
2024
·Vol. 10
·期 11
·720
·
IF 5
Weidan Na,Chao Xu,Lei An,Changjin Ou,Fan Gao,Guoyin Zhu,Yizhou Zhang
Conductive hydrogels are promising active materials for wearable flexible electronics, yet it is still challenging to fabricate conductive hydrogels with good environmental stability and electrical properties. In this work, a conductive MXene/LiCl/poly(sulfobetaine methacrylate) hydrogel system was successfully prepared with an impressive conductivity of 12.2 S/m. Interestingly, the synergistic effect of MXene and a lithium bond can significantly accelerate the polymerization process, forming the conductive hydrogel within 1 min. In addition, adding LiCl to the hydrogel not only significantly increases its water retention ability, but also enhances its conductivity, both of which are important for practical applications. The flexible strain sensors based on the as-prepared hydrogel have demonstrated excellent monitoring ability for human joint motion, pulse, and electromyographic signals. More importantly, based on machine learning image recognition technology, the handwritten letter recognition system displayed a high accuracy rate of 93.5%. This work demonstrates the excellent comprehensive performance of MXene-based hydrogels in health monitoring and image recognition and shows potential applications in human–machine interfaces and artificial intelligence.
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INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH
·
2024
·
IF 3.8
Shicheng Cao,Chengzhi Hu,Guoxian Wang,Kai Wang,Zhangxian Chen,Zeheng Yang,Weixin Zhang
Hydrated vanadate possesses a large layer distance and rich vanadium redox center superior for flexible electrochromic devices (FECDs). However, the low mechanical strength and high interfacial impedance caused by the low processing temperature pose key challenges. This study presents the successful development of an all-climate solid-state FECD using a hydrate vanadate/MXene composite and hydrogel electrolyte. The integration of high-crystallinity, layer-structured V2O5·1.6H2O with two-dimensional MXene nanoflakes facilitates fast ion transfer, enabling excellent electrochromic properties with fast responses (Coloring time = 5.8 s; Bleaching time = 9.8 s), large optical modulation (64.02%), coloring efficiency, and high flexibility. The hydrogel electrolyte provides strong mechanical strength and a wide operating temperature range between −10 and 55 °C. This work signifies a critical step toward the application of FECDs in smart windows, offering a promising solution for environments requiring high flexibility and climate resilience.
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INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH
·
2025
·
IF 3.9
Pengcheng Deng,Nanjing Li,Ye Feng,Zhiqing Liu,Canhui Lu,Zehang Zhou
With the rapid advancement of electronic technology, the demand for wearable and portable electronic devices has significantly increased. MXene-based multifunctional textiles have attracted extensive attention from researchers due to their unique various functionalities, while the poor oxidation and structure stability limit their applications. In this study, a novel MXene/tannic acid-modified cellulose nanofibers (TACNF)-based multifunctional textile was prepared by screen-printing and post treatment. The abundant phenolic hydroxyl groups in TA effectively protect the MXene nanosheets from oxidation. The subsequent ZnCl2 cross-linking treatment leads to the metal coordination between Zn ions and TA molecules, which further improves the structure stability of the composite coating and endows the functional textile with enhanced antimicrobial activity against Escherichia coli and Staphylococcus aureus. The composite textile with a rationally designed electrically conductive structure demonstrates decent sensing ability toward tiny and large human motions, and its exceptional photo-/electro-thermal conversion ability also enables promising potential applications in thermal therapy and heat sterilization. This study provides new insights for the design and fabrication of smart healthcare textiles.
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Journal of Materials Chemistry A
·
2024
·
IF 10.7
Yuanna Sun,Ying Du,Yu Zhang,Jie Yang,Jiahao Liu,Ruobing Tian,Junbo Wang,Qingshan Li,Xinhai He,Jun Fu
Conductive hydrogels are viewed as the most promising materials for flexible devices. However, their applications in aquatic environments are severely limited by their inevitable swelling behavior. Herein, we report a MXene-based polyampholyte anti-swelling hydrogel possessing high stretchability (1391%), good conductivity, admirable self-healing ability (healing efficiency reached 66% after healing for 1 h), and fast photoresponsive behavior. Besides, the hydrogel-based sensor displayed a wide sensing range (2–400%) and could realize underwater monitoring and communication. More importantly, an underwater warning system was assembled, which can offer efficient real-time underwater positioning and urban waterlogging pre-warning. This work provides a new strategy for developing anti-swelling hydrogel sensors and expands their potential applications in marine exploitation and urban construction.
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CRYSTENGCOMM
·
2024
·Vol. 26
·期 38
·5440-5451
·
IF 2.6
Xiaoyun Ye,Hangyu Zhong,Yumei Zhang,Xuehua Liu,Wei Tian,Li-An Ma,Qianting Wang
Previous studies on photocatalytic technology have shown that doping co-catalysts and constructing composite heterojunctions are effective strategies for improving the photocatalyst performance. The Ti3C2/SrTiO3/g-C3N4 composite photocatalyst with a gradient heterostructure was prepared by the high-temperature calcination method with Ti3C2 as the co-catalyst. The effects of g-C3N4 content on the microstructure and hydrogen evolution rate of the Ti3C2/SrTiO3/g-C3N4 composites were investigated under simulated sunlight. The results showed that the photocatalyst with 60 wt% of g-C3N4 had the optimal hydrogen evolution rate of 1733.13 μmol g−1 h−1 after simulated sunlight irradiation for 4 h, which was approximately 3.3 times higher than that of Ti3C2/SrTiO3. After four photocatalytic hydrogen evolution cycles, no significant decrease in the hydrogen evolution rate of the Ti3C2/SrTiO3/g-C3N4 composite was observed. This work may serve as a rational reference on the synergistic effect of heterostructures and cocatalysts to improve the separation effect of electron–hole pairs, thus improving the hydrogen evolution effect of the catalyst.
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COMPOSITES COMMUNICATIONS
·
2024
·
IF 6.5
Di Zhang,Yue Ren,Yahong Li,Yuezhan Feng,Bing Zhou,Chuntai Liu
Application of three-dimensional (3D) carbon framework in phase change material (PCM) has aroused a tremendous interest. However, implementing a high alignment carbon framework with low interfacial thermal resistance (ITR) remain challenging. Herein, we demonstrated a synergetic effect strategy by Ti 3 C 2 T x MXene and graphene nanoplate (GNP) to achieve a 3D thermally conductive framework with high alignment skeleton and low filler-to-filler ITR. Typically, the 3D anisotropic carbon framework is fabricated by unidirectional ice template freezing cellulose nanofibers (CNF)/GNP solution with the assistance of MXene. The abundant functional groups of MXene and the similar layered structure promote the dispersion stability of GNP in CNF aqueous solution, resulting in the significant improvement in GNP alignment and the filler-to-filler ITR. Therefore, the final phase change composites obtained by impregnating polyethylene glycol (PEG) into the framework achieves a satisfactory thermal conductivity (TC) of up to 3.49 W/m K at only 6.25 vol% filler loading. Combining the solar-thermal conversion ability of graphene and MXene, the PCM reveals a rapid energy conversion, transfer and storage capability. More importantly, the phase change enthalpy of the PCM can be as high as 164.3 J/g, with little change even after 50 heating-cooling cycles, and the existence of carbon framework can effectively prevent the leakage phenomenon in solid-liquid conversion process, ensuring its shape stability.
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Materials Today Chemistry
·
2024
·
IF 6.7
Linwei Li,Zihan Xing,Tao Liao,Jinyu Wang,Ziqiang Xu,Ying Kuang,Cao Li
Chemodynamic therapy (CDT) is a new cancer treatment that uses low-valence transition metal ions to catalyze intracellular Fenton/Fenton-like reactions, producing hydroxyl radicals (•OH) to eliminate cancer cells. However, achieving satisfactory therapeutic outcomes with CDT alone can be challenging. In this work, we reported an anticancer drug delivery DOX@HMDN-TQDs@PEI-PEG (DMTP) based on hollow mesoporous manganese dioxide nanoparticle (HMDN), which has the potential to improve cancer therapy by combining synergistic therapeutic and tumor magnetic resonance imaging (MRI) capability. After loading the anticancer drug doxorubicin hydrochloride (DOX), the pores of HMDN were sealed with polyethyleneimine (PEI) modified Ti 3 C 2 T x MXene quantum dots (TQDs) and finally modified with polyethylene glycol (PEG) to obtain the final system. HMDN depletes glutathione (GSH), which is harmful to CDT, in cancer cells, and generates Mn 2+ that can be used for both CDT and MRI. TQDs can also be used for highly effective photothermal therapy (PTT) that enhances CDT. The combination of DOX with chemotherapy can significantly inhibit tumor growth. In addition, DMTP combines the capability of tumor MRI as Mn 2+ is also a T 1 -weighted contrast agent . This multifunctional delivery system provides new ideas for research related to tumor diagnosis and treatment.
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IEEE SENSORS JOURNAL
·
2024
·
IF 4.3
Bichan Huang,Yingjie Niu,Dejin Yan,Xiaoming Chen,Teng Ma,Zhenxiang Xiong,Zihang Wang,Hui Cheng,Chenglin Yi
The rising demand for lightweight and flexible pressure sensors with sensitive sensing capabilities and resistance to high temperature is evident across various applications. However, effectively integrating these advantages in a harmonious manner poses a significant challenge. Here, an ultralight graphene oxide (GO)/MXene aerogel with low density (19 mg/cm3) has been fabricated, demonstrating excellent temperature resilience ranging from -55 °C to 300 °C. The flexible piezoresistive sensor is developed utilizing a simple vacuum freeze-drying method. The as-obtained flexible pressure sensor exhibits a notable sensitivity of 62.65 kPa
-1
, a rapid response time of 55 ms, a wide detection range of 0.2 Pa to 23 kPa, and commendable durability verified by over 5000 loaded-unloaded cycles (up to 40% strain). The sensor can detect human movements including wrist bending, finger picking, swallowing and blowing. It has exhibited exceptional pressure sensing capabilities over a wide range of -55 °C to 300 °C. The proposed polymer-free aerogel is anticipated to exhibit a broad range of temperature resistance, enhancing its potential for future applications such as energy storage and aerospace.
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Journal of the American Chemical Society
·
2024
·
IF 14.4
Yanliang Zhou,Lili Liang,Congying Wang,Fuxiang Sun,Lirong Zheng,Haifeng Qi,Bin Wang,Xiuyun Wang,Chak-tong Au,Junjie Wang,Lilong Jiang,Hideo Hosono
To date, NH3 synthesis under mild conditions is largely confined to precious Ru catalysts, while nonprecious metal (NPM) catalysts are confronted with the challenge of low catalytic activity due to the inverse relationship between the N2 dissociation barrier and NHx (x = 1–3) desorption energy. Herein, we demonstrate NPM (Co, Ni, and Re)-mediated Mo2CTx MXene (where Tx denotes the OH group) to achieve efficient NH3 synthesis under mild conditions. In particular, the NH3 synthesis rate over Re/Mo2CTx and Ni/Mo2CTx can reach 22.4 and 21.5 mmol g–1 h–1 at 400 °C and 1 MPa, respectively, higher than that of NPM-based catalysts and Cs–Ru/MgO ever reported. Experimental and theoretical studies reveal that Mo4+ over Mo2CTx has a strong ability for N2 activation; thus, the rate-determining step is shifted from conventional N2 dissociation to NH2* formation. NPM is mainly responsible for H2 activation, and the high reactivity of spillover hydrogen and electron transfer from NPM to the N-rich Mo2CTx surface can efficiently facilitate nitrogen hydrogenation and the subsequent desorption of NH3. With the synergistic effect of the dual active sites bridged by H-spillover, the NPM-mediated Mo2CTx catalysts circumvent the major obstacle, making NH3 synthesis under mild conditions efficient.
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