CHEMICAL ENGINEERING JOURNAL
·
2025
·
IF 13.2
Kui Zhang,Ziqing Guo,Kaiwen Wang,Yuxuan Zhu,Juan Yang,Lijin Huang,Yuanyuan Zhang,Nianjun Yang
The development of highly selective enzyme-free electrochemical sensors remains challenging, particularly in complex biological environments containing multiple electroactive interferents. To address this issue, we present a hierarchical sensing interface by innovatively growing a zeolitic imidazolate framework-8 (ZIF-8) film on three-dimensional AuPt nanoalloys. This design capitalizes on the molecular sieving effect of ZIF-8, which allows selective permeation of H 2 O 2 to the underlying catalytic AuPt surface while effectively blocking larger interferents such as ascorbic acid, uric acid, and dopamine. The resulting sensor exhibits exceptional selectivity, enabling accurate detection of H 2 O 2 even in the presence of interferents at concentrations 20-fold higher. Moreover, through the controllable growth of the ZIF-8 film and the high catalytic activity of the AuPt nanoalloy, the optimized sensor also demonstrates high sensitivity, a wide linear range, and a low detection limit. It was also successfully applied to in situ tracking of H 2 O 2 release from live cervical and breast cancer cells. This work provides a novel strategy for constructing metal-organic framework-based heterostructures for highly selective sensing, paving the way for reliable H 2 O 2 monitoring in biomedical applications.
✓ 已验证
产品关联
DOI
高影响因子
FUEL
·
2025
·
IF 7.5
Dongju Fu,Zhao Hu,Jinghui Xun,Xiao Yu,LuYang Wang,Shaozhong Zeng,Fengjiao Li
Highly ordered Pt alloy structure is an effective method to improve the catalytic activity and stability of cathodic oxygen reduction reaction (ORR) in acidic media, which is of great significance for the large-scale commercial application of proton exchange membrane fuel cells (PEMFCs). Herein, a highly efficient and durable catalyst composed of structurally ordered PtCo alloys with nitrogen-doped carbon (NC) shells is designed by improving the impregnation reduction method, using an intermediate self-sacrificial template strategy. Under the optimal preparation conditions of 20 wt% doped Ketjen black and a calcination temperature of 850 °C, the ordered PtCo alloy-based catalyst (denoted as L 1 0 -PtCo/ZNC) is obtained with an average nanoalloy size of about 3.9 nm and uniformly loaded on the N-doped carbon support via pyrolysis of cobalt-based zeolite imidazolate framework (ZIF-67) and carbon black. The half-wave potential ( E 1/2 ) of L 1 0 -PtCo/ZNC reaches 0.927 V vs. RHE, outperforming most of the reported catalysts and the benchmark commercial Pt/C catalyst. Moreover, the mass activity (MA, 1.06 A mg Pt -1 ) and specific activity (SA, 1.03 mA cm -2 Pt ) of L 1 0 -PtCo/ZNC are 7.6 and 4.7 times of those of Pt/C, respectively. The MA and SA values of L 1 0 -PtCo/ZNC after 10,000 cycles are 35 and 23 times of those of Pt/C catalysts, respectively, indicative of the excellent durability of L 1 0 -PtCo/ZNC. This method provides an effective strategy in preparing highly active and stable ordered PtCo alloy-based hybrid catalysts for acid ORR.
✓ 已验证
产品关联
DOI
高影响因子
Biosensors-Basel
·
2022
·Vol. 12
·期 10
·830
·
IF 5.743
Juanjuan Huang,Yiyun Yao,Yanling Chen,Tianran Lin,Li Hou,Dianping Tang
Copper peroxide/zeolitic imidazolate framework/polydopamine nanoparticles (CP/ZIF-8/PDA)-based fluorescence-linked immunosorbent assay (FLISA) was designed for the sensitive and high-throughput determination of carcinoembryonic antigen (CEA) by self-supplied H2O2generation. Specifically, the CEA aptamer was modified on the surface of CP/ZIF-8/PDA to form an immunoprobe. The structures of CP and ZIF-8 could be broken under acidic conditions, and produced the Cu2+and H2O2due to the dissociation the CP. A subsequent Fenton-type reaction of Cu2+and H2O2generated hydroxyl radical (·OH). o-phenylenediamine (OPD) was oxidized by the ·OH to form 2, 3-diaminophenazine (DPA) with a significant fluorescence signal. CP/ZIF-8/PDA could be used as an efficient Fenton-type reactant to generate a large amount of ·OH to promote OPD oxidation. The sensitive detection of CEA could be realized. Under optimal conditions, the FLISA platform displayed a linear detection range from 0.01 to 20 ng mL−1with a detection limit of 7.6 pg mL−1for CEA. This strategy has great application potential for sensitive and high-throughput determination for other biomarkers in the field of biomedicine.Keywords:fluorescence-linked immunosorbent assay;Fenton-type reaction;carcinoembryonic antigen
✓ 已验证
DOI
PubMed
高影响因子
JOURNAL OF HAZARDOUS MATERIALS
·
2020
·
IF 9.038
Yang Wang,Lei Zhang
In this paper, we report a new type of 3D ZIF-8@NiAl-LDHs micro-flowers material consisting of sandwich-like structured 2D nanopetals (highly compact ZIF-8 film anchored on both sides of petals). ZIF-8 was successfully incorporated into NiAl-LDHs (ZIF-8@NiAl-LDHs) via seeding strategy directed growth of ZIFs on the surface of LDHs nanopetals. The coating of ZIF-8 significantly increased the adsorption ability to organic pollutants and inorganic cation. 3D ZIF-8@NiAl-LDHs with excellent enrichment and filtration properties has been exploited for the application in water purification, and exhibit superior high adsorption rate and adsorption efficiency of organic (nonsteroidal anti-inflammatory drugs: ketoprofen, flurbiprofen, indometacin and ibuprofe; anionic dyes: congo red, orange g; cationic dyes: methylene blue, rhodamine b) and inorganic cation (Cu 2+ , Pb 2+ ) residues due to their novel hierarchical and submicroscopic structures. Further, 3D ZIF-8@NiAl-LDHs as filter membrane to extraction four kind of trace anti-inflammatory drugs followed by direct quantification detection of targets with HPLC was demonstrated. The validated method was successfully applied for analysis of four anti-inflammatory drugs in environmental water and human urine samples. This work provided a feasible way to design and construct purification materials for wastewater treatment and contaminant detection.
✓ 已验证
DOI
高影响因子
MOLECULES
·
2022
·Vol. 27
·期 21
·7488
·
IF 4.927
Wenjie Zhang,Jianlin Long,Haijun Wang,Jinle Lan,Yunhua Yu,Xiaoping Yang
Polymer electrolytes (PEs) with high flexibility, low cost, and excellent interface compatibility have been considered as an ideal substitute for traditional liquid electrolytes for high safety lithium metal batteries (LMBs). Nevertheless, the mechanical strength of PEs is generally poor to prevent the growth of lithium dendrites during the charge/discharge process, which seriously restricts their wide practical applications. Herein, a mechanical robust ZIF-8/epoxy composite electrolyte with unique pore structure was prepared, which effectively inhibited the growth of lithium dendrites. Meanwhile, the in situ growth of ZIF-8 in porous epoxy matrix can promote the uniform flux and fast transport of lithium ions. Ultimately, the optimal electrolyte shows high ionic conductivity (2.2 × 10−3S cm−1), wide electrochemical window (5 V), and a large Li+transference number (0.70) at room temperature. The Li||NCM811 cell using the optimal electrolyte exhibits high capacity and excellent cycling performance (83.2% capacity retention with 172.1 mA h g−1capacity retained after 200 cycles at 0.2 C). These results indicate that the ZIF-8/epoxy composite electrolyte is of great promise for the application in LMBs.
✓ 已验证
DOI
高影响因子
ChemCatChem
·
2017
·Vol. 10
·期 4
·796-803
·
IF 4.803
Shi Feng,Xingyue Li,Jia Huo,Qiling Li,Chao Xie,Tingting Liu,Zhigang Liu,Zhenjun Wu,Shuangyin Wang
Graphical Porous carbon electrode : CoS 2 @N/S-codoped porous carbon is prepared through an electrodeposition–ZIF conversion–sulfuration strategy. The loading of active sites can be controlled easily by varying the electrodeposition time. The resulting material can be employed directly as a working electrode for the hydrogen evolution reaction and shows an excellent catalytic activity and stability. A convenient, controllable method to fabricate an electrode is necessary to achieve the practical application of a hydrogen evolution reaction (HER) catalyst. In this work, an electrodeposition–ZIF conversion–sulfuration strategy is developed to produce a CoS 2 @N/S-codoped porous carbon (CoS 2 @NSC/CFP) to drive the HER efficiently. CoS 2 @NSC/CFP was prepared by the electrodeposition of Co(OH) 2 on a carbon fiber paper followed by conversion into ZIF-67 and subsequent sulfuration with sulfur. The loading of electroactive components can be controlled easily in the range of 0.7–10.0 mg cm −2 by varying electrodeposition time from 5 min to 2 h. The resulting material can be employed directly as a working electrode for the HER and it shows an excellent catalytic activity and stability with an overpotential of 95 mV at 10 mA cm −2 and 158 mV to reach 100 mA cm −2 in an acidic medium. The high efficiency is related intimately to the high dispersion of ultra-small CoS 2 nanoparticles, heteroatom-codoping, and the 3 D porous network configuration of the carbon fiber paper.
✓ 已验证
DOI
高影响因子
ACS Applied Materials & Interfaces
·
2022
·
IF 10.383
Fuwei Liang,Yang Xu,Shun Chen,Yalin Zhu,Yaxun Huang,Bin Fei,Wenwen Guo
The facile construction of a cotton fabric with excellent flame-retardant and water-proof abilities is of great interest for multitask requirements. Herein, a nonfluorine, highly efficient, and cost-effective multifunctional cotton fabric was fabricated via sequentially depositing a novel multielement-containing flame-retardant phosphorylated octa-aminopropyl POSS (PPA-POSS) and a fluorine-free superhydrophobic coating of zeolitic imidazolate framework-67@poly(dimethylsiloxane) (ZIF-67@PDMS). Influences of the PPA-POSS concentration and ZIF-67@PDMS formula on the fire retardancy and water repellency of treated cotton were systematically investigated. The optimized flame-retardant sample CTF3 with 6.2 wt % PPA-POSS exhibited a high limiting oxygen index (LOI) of 34% and self-extinguishing ability. CTF3 was further modified with a properly formulated superhydrophobic ZIF-67@PDMS coating. CTF3-PHB2 displayed enhanced thermal stability, flame retardancy, and outstanding superhydrophobicity. Thermogravimetric analysis (TGA) results demonstrated that CTF3-PHB2 presented a high char residue of 35.9%, which was 220.5% higher than that of the control cotton (11.2%). More importantly, the heat release rate (HRR), total heat release (THR), and average effective heat of combustion (av-EHC) values of CTF3-PHB2 were significantly reduced by 51.4, 56.2, and 68.4%, respectively, compared with those of a pure cotton fabric. Moreover, CTF3-PHB2 showed superhydrophobicity (WCA > 159.3°) and good mechanical abrasion resistance. In addition, CTF3-PHB2 also showed protective abilities such as antifouling, self-cleaning, and water/oil separation performances even for strong acid/alkali mixtures. Thereby, it is believed that the PPA-POSS@ZIF-67@PDMS coating is promising for application in multifunctional textile materials.
✓ 已验证
DOI
高影响因子
Journal of Materials Chemistry B
·
2021
·Vol. 9
·期 43
·9031-9040
·
IF 6.331
Jilin Zheng,Peng Zhao,Shiying Zhou,Sha Chen,Yi Liang,Fengchun Tian,Jun Zhou,Danqun Huo,Changjun Hou
Integrating metal–organic frameworks (MOFs) of different components or structures together and exploiting them as electrochemical sensors for electrochemical sensing has aroused great interest. Furthermore, the incorporation of noble metals with MOFs is conducive to the improvement of catalytic performance. In this work, Pd@UiO-66-on-ZIF-L nanomaterials were successfully synthesised onto a self-supported flexible carbon cloth (Pd@UiO-66-on-ZIF-L/CC) through a novel strategy called MOF-on-MOF. Then, Au nanoparticles were electrodeposited onto Pd@UiO-66-on-ZIF-L/CC to obtain Au–Pd@UiO-66-on-ZIF-L/CC, which can serve as an excellent electrocatalyst for the reduction of hydrogen peroxide (H2O2). The obtained flower-like Pd@UiO-66-on-ZIF-L/CC hybrid MOF changes the structure of the monomeric MOF alone and adds more attachment sites. The synergy of the bimetals greatly improved the catalytic performance of the as-developed sensor. Electrochemical experiment results show that the proposed sensor based on Au–Pd@UiO-66-on-ZIF-L/CC has an extended linear range from 1 μM to 19.6 mM with a sensitivity of 390 μA mM−1 cm−2, and a low limit of detection (LOD) of 21.2 nM (S/N = 3). Moreover, it has good anti-interference, reproducibility, repeatability and excellent stability. Furthermore, the real-time in situ detection of H2O2 secreted from human adenocarcinomic alveolar basal epithelial cells (A549 cells) was achieved by culturing cells on Au–Pd@UiO-66-on-ZIF-L/CC, which indicates the potential of the sensor for applications in cancer pathology. Both the synthesis strategy and the sensor design provide new methods and ideas for the production of ultrasensitive H2O2 electrochemical sensors.
✓ 已验证
DOI
PubMed
高影响因子
Materials Science & Engineering C-Materials for Biological Applications
·
2021
·
IF 7.328
Ying Jiang,Yi Lu,Lingli Lei,Shengyu Zhou,Lu Yang,Xiaoyan Yang,Zhigang Xu,Jing Liu,Yingshuai Liu
Reactive oxygen species (ROS) with strong oxidability have been considered as effective agents for antitumor therapy through oxidative damage to lipids, proteins, DNA and RNA. In this work, a multifunctional hollow cobaltosic sulfide (Co 3 S 4 )/photosensitizer indocyanine green (ICG) nanocomplex (Co 3 S 4 -ICG) has been synthesized by efficiently loading ICG into the hollow Co 3 S 4 to realize synergistic antitumor therapy via chemodynamic therapy (CDT), photodynamic therapy (PDT) and photothermal therapy (PTT) under near-infrared (808 nm) laser irradiation. Co 3 S 4 nanoparticles would be degraded in tumor acidic microenvironment into Co 2+ , which locally triggers a Fenton-like reaction to produce cytotoxic hydroxyl radicals ( OH) for CDT. Co 3 S 4 -ICG could also produce singlet oxygen ( 1 O 2 ) through a multi-step photochemical process for PDT under 808 nm laser irradiation. The slow release of ICG in the tumor region was achieved due to hollow-structured Co 3 S 4 working as nanocarriers, and which has been proved an effective approach for combined CDT/PDT. In addition, Co 3 S 4 -ICG showed high photothermal conversion efficiency (40.5%) for PTT, and excellent OH generation capability via photothermal-improved Fenton reaction, leading to the synergistically improved antitumor efficacy. In vitro and in vivo experimental results confirm that the combined PTT/PDT/photothermal-enhanced CDT therapy can effectively ablate tumors with a negligible systemic toxicity. This work provides a valuable strategy for designing and constructing of a multifunctional nanoplatform for synergistic antitumor therapy of solid tumors.
✓ 已验证
DOI
PubMed
高影响因子
DALTON TRANSACTIONS
·
2016
·Vol. 46
·期 2
·554-563
·
IF 4.177
Erbin Shi,Huiming Lin,Qian Wang,Feng Zhang,Shaoxuan Shi,Tingting Zhang,Xin Li,Hao Niu,Fengyu Qu
A novel ZIF-Ni composite film has been successfully prepared by a facile method involving the in situ deposition of ZIF-8 on a nickel porous film which is fabricated by selectively etching copper from a dense Ni/Cu alloy film. The nanostructures of the resulting ZIF-Ni composite films are carefully examined by a combination of scanning electron microscopy (SEM), X-ray diffraction (XRD) analysis, Fourier transform infrared (FT-IR) spectroscopy, energy dispersive X-ray (EDX), and nitrogen adsorption–desorption. Cyclic voltammetric and amperometric studies show the enhanced electrocatalytic properties of the ZIF-Ni composite film electrodes toward hydrazine oxidation relative to the synergistic effect of ZIF-8 and porous Ni films. The application potential of the composite films as amperometric detectors is explored for the determination of hydrazine. A high sensitivity of 805.5 μA mM−1 for hydrazine detection with a low detection limit of 0.021 μM (S/N = 3) and a wide linear range from 2.5 μM to 28 mM are revealed for this new type of composite film as the detecting electrode. Moreover, the composite films exhibit excellent selectivity and remarkable stability for the oxidation of hydrazine. This can offer new opportunities for the fast and selective detection of hydrazine and provide a promising platform for sensor designs for hydrazine detection.
✓ 已验证
DOI
高影响因子
CHEMICAL ENGINEERING SCIENCE
·
2023
·
IF 4.7
Xinhui Liu,Chen Yan,Yilin Wang,Peng Zhang,Siyan Yan,Hanbin Wang,Jianguo Zhuang,Yitao Zhao,Yuchen Wang,Yijun Yu,Qichao Zhao,Xuedong Zhu,Fan Yang
A series of Zn loaded ZSM-5 (Zn/ZSM-5) zeolites were prepared utilizing either Zn(NO 3 ) 2 or Zn-based MOFs (ZIF-61, ZIF-8 and ZIF-14) as Zn sources to explore their effects on the catalysts’ physiochemical properties through characterizations and simulations. Results revealed that hierarchical structures containing meso - to macro- pores of 10 ∼ 80 nm aside from the intrinsic micropores were constructed profiting from the use of Zn-based MOFs. On the other side, lager proportions of medium acid and Lewis acid sites were generated by more Zn(OH) + , whose content was proven to be inextricably linked to the binding energy between Zn and ligand as well as local charge valence state of Zn. Benefitting from hierarchical structures and balanced acidities, Zn/Z5(ZIF-14) employing ZIF-14 as Zn source demonstrated higher aromatic selectivity and longer catalyst lifetime (50.9 % and 26 h) than the microporous counterpart synthesized from zinc nitrate hexahydrate (42.1 % and 20 h) in methanol to aromatics (MTA) reaction.
✓ 已验证
DOI
高影响因子
SENSORS AND ACTUATORS B-CHEMICAL
·
2026
·
IF 8.3
Xuhan Wang,Xiaoning Meng,Wei Gao
Hydrophobic ZIF-8 was grown on PdPt/WO 3 for room‑temperature H 2 detection under 90% RH. • ZPPW-2.0 sensor achieved ultrahigh response (15976.29) to 5000 ppm H 2 at 25℃ under 90% RH. • Dual sieving provided excellent selectivity against interfering gases. • Red‑light excitation enhanced sensitivity via oxygen‑vacancy activation. • Multi‑mechanism design ensured humidity‑tolerant and stable performance. This study presented the development of a room-temperature hydrogen (H 2 ) gas sensor, designated ZPPW-2.0, capable of operating reliably under high-humidity conditions. The sensor structure was constructed by growing hydrophobic zeolitic imidazolate framework (ZIF-8) on a PdPt-modified WO 3 sensing film. This configuration enabled a synergistic surface regulation mechanism involving molecular sieving, surface defect engineering and photoexcitation-enhanced surface reactivity. Under ambient operating conditions (25°C, 90% relative humidity), the sensor exhibited a remarkable response of 15976.29 to 5000 ppm H 2 , a response time of 8 s, excellent repeatability, long-term stability, and outstanding selectivity. Furthermore, illumination with 655–660 nm red light could enhance performance. The observed high performance was attributed to the synergistic enhancement by surface defect states, effective exposure of surface active sites, inhibition of surface water competition, and molecular sieving. This work highlighted the central role of surface reaction, and interfacial regulation in designing reliable room-temperature H 2 sensors for humid environments. Download: Download high-res image (274KB) Download: Download full-size image
✓ 已验证
DOI
高影响因子
危险品化学品经营许可证（带存储）