COLLOIDS AND SURFACES B-BIOINTERFACES
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2022
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IF 5.999
Jianbo Lin,Rujie Zheng,Liping Huang,Yuanrong Tu,Xu Li,Jianfeng Chen
Molecularly targeted drugs are flourishing in the clinical treatment of non-small cell lung cancer (NSCLC). However, the treatment of a single drug (such as Gefitinib (Geb)) had defects such as poor pharmacokinetics , insufficient drug delivery, and considerable toxic side effects, which greatly affect its therapeutic efficacy against NSCLC. To solve these issues, this study developed a new nanocomposite heterogeneous platform (MSNs@Ag@Geb-FA) that combined photothermal therapy and molecular targeted therapy. The high specific surface area empowered mesoporous silicon dioxide (SiO 2 ) heterostructure the ability to efficiently load Ag photothermal agents and anti-tumor drug Geb. Meanwhile, a favorable pH response (degradation of residual MnO 2 ) achieved the controlled release of Ag and Geb. Besides, the targeting and endocytosis properties of nano drugs were greatly improved through the modification of folic acid (FA). Both in vivo and in vitro experiments authenticated that this nanocomposite heterogeneous platform could effectively integrate the multiple tumor suppressor properties of Ag nanoparticles and cooperate with Geb to hasten A549 cell apoptosis, thereby achieving a favorable anti-tumor effect. This heterogeneous structure of the nanocomposite heterogeneous platform could provide an effective strategy for the treatment of NSCLC.
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PubMed
高影响因子
POLYMER TESTING
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2022
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IF 4.931
Qiao Li,Guangyi Lin,Su Zhang,Haitong Wang,Jyotishmoy Borah,Yuan Jing,Fumin Liu
In the present scenario of development in technology, the applications of stretchable conductive elastomers in modern electronic equipments have aroused great interest. Non-covalent bonding modification of carbon nanotubes (CNTs) using dopamine has improved the dispersion of CNT@PDA and interfacial interaction with the rubber matrix. The SiO 2 @Ag core-shell particles were prepared by coated with silver nanoparticles (AgNPs) on the surface of SiO 2 using dopamine oxidation self-polymerization and electroless plating process. ESBR composites were prepared by latex co-coagulation method, where CNT@PDA and SiO 2 @Ag were used to develop an 1D-3D synergistic conductive network in ESBR composites. One-dimensional (1D) CNT@PDA were incorporated in three-dimensional (3D) spherical SiO 2 @Ag core-shell particles, which effectively prevented the agglomeration of SiO 2 @Ag and CNT@PDA. Again, 1D CNT@PDA could also be used as bridges to interact with 3D SiO 2 @Ag to develop the charge transfer more effectively in ESBR composites. The optimum electrical conductivity of the ESBR/CNT@PDA/SiO 2 @Ag composites was 0.2 S/cm, which was found to be higher than that of single filler. Moreover, the high electrical conductivity can be controlled at low tensile strain. The mechanical property of ESBR/CNT@PDA/SiO 2 @Ag composite was also improved by 105.4% as compared by ESBR/CNTs. This work provides a new idea for the fabrication of stretchable conductive elastomer composites with high performance.
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ACS Applied Nano Materials
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2022
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IF 6.14
Hewen Yin,Yongya Zhang,Hui Dong,Lantao Liu,Xiaobing Wang,Yintang Zhang,Maotian Xu,Yanli Zhou
In this work, in situ confinement polymerization was developed for the formation of silver nanoclusters (AgNCs) homogeneously distributed on nitrogen-doped carbon (NCS) utilizing N-vinyl functionalized imidazolium ionic liquids (ILs) as stabilizers and carbon precursors. The fabricated AgNC@NCSs exhibited excellent electrochemical and catalytic properties due to their controlled structure and morphology, the unique layered structure of the carbon carriers, and the confinement effect. The AgNC@NCS material was further fabricated for a printing electrode, which also acted as an internal reference for ratiometric and accurate detection. Nitrite was used as a target to verify the feasibility of self-calibrating detection at the AgNC@NCS printing electrode. The present electrochemical sensor demonstrated superior nitrite sensing characteristics, accompanied by a wide linear range (1.12–1400 μM), low detection limit (0.38 μM), high stability, and strong anti-interference ability. Importantly, high reliability of this self-calibrating detection was obtained for nitrate determination in food samples. Our work provides an efficient strategy for the design of self-calibrating electrodes in the area of electrochemical sensing.
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OPTICAL MATERIALS
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2022
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IF 3.754
Weili Huang,Junhui Yi,Xiaoying Liao,Changquan Jiao,Runkun Xie,Beifang Chen,Zebo Lin,Yupeng Yang,Weitao Liu,Huimei Mo
AgVO 3 and AgI have attracted great interest in environmental remediation. Aiming at enhancing the catalytic activity and stability of AgVO 3 . Visible light response Z-scheme AgI/Ag/AgVO 3 hybrid nanorods were prepared by in situ reduction and ion exchange grown. The results of characterization and experiment showed that obtained hybrid material are primarily composed of AgVO 3 nanorods, whose surface were closely attached to AgI and Ag particles. Compared with AgVO 3 and Ag/AgVO 3 , the absorbance of Z-scheme AgI/Ag/AgVO 3 hybrid nanorods in the visible light region is dramatically enhanced. The degradation efficiency of sample is five times of that of AgVO 3 and four times of that of Ag/AgVO 3 , respectively. And the degradation efficiency still keep 90% after the fourth repeat experiment. The trapping experiments of active species confirmed that the contribution of the degradation for AO-II is mainly attributed to h + and ∙O 2 − . The efficient photocatalytic activity can be explained by Z-type mechanism, which promote effective separation of photogenerated charges. This study provides an idea for the design of efficient visible light photocatalysts .
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SENSORS AND ACTUATORS B-CHEMICAL
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2022
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IF 9.221
Xin Shang,Jiayang He,Chunli Yang,Siyu Zuo,Ruo Yuan,Wenju Xu
Development of logic AND-gated multivariate assay systems of DNA-scaffolded green- and red-fluorescent Ag nanoclusters ( g- AgNC and r- AgNC) is promising and remains challenging. By using two DNA segments ( T o and T r) as dual-targeting inputs, herein we report an innovative strategy that utilizes targets-recycled amplification to create a sensitive AND-gated light-up ratiometric sensor with reversely changed fluorescence of g- AgNC and r- AgNC. The design is based on that: two hairpins ( H o and H r) are individually recognizable to T o and T r, and two hybridized duplexes are resultantly implemented for transient dissipative base pairing, i.e. H o· H r, releasing T o and T r for repeated recycling. In an original stem-loop hairpin reporter (HR), one exposed overhang is to host g -AgNC. When HR is unfolded by the cooperative sticky toeholds in H o∙ H r, its liberated stem merging with the g -AgNC template is for r- AgNC clustering. Only when meeting simultaneously the overexpressed T o and T r in SARS-CoV-2, the AND-gated ratio fluorescence of r- AgNC over g- AgNC can be lighted-up in a typical assay, enabling highly specific-inputs binding and sensitive dose-dependence down to 0.29 pM. This enzyme-free and label-free AND-logic ratiometirc strategy illustrates the potential of using multicolor AgNCs emitters for more accurate multivariate assay.
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MICROCHEMICAL JOURNAL
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2022
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IF 5.304
Ziyu Xue,Dehong Bai,Yu Li,Qiankun Zhang,Tao shao,Peiqing Guo,Dongxia Zhang,Xibin Zhou
In this work, a simple strategy for the rapid detection of Ag + based on nitrogen, sulfur doped graphene quantum dots (N, S-GQDs) decorated platinum nanoclusters (PtNCs) was proposed for the first time. N, S-GQDs decorated PtNCs (N, S-GQDs@PtNCs) were prepared by a reduction method using ascorbic acid (AA) as reducing agent and N, S-GQDs as a stabilizer and morphology directing reagent, respectively. The N, S-GQDs@PtNCs have an excellent peroxidase activity, which could catalyze the oxidation of 3,3′,5,5′-tetramethylbenzidine (TMB) by H 2 O 2 to lead to an obvious color change. However, Ag + could be reduced to Ag 0 by N,S-GQDs, and the Ag 0 covered the surface of N, S-GQDs@PtNCs causing its peroxidase activity to decrease. Ag + concentration could be quantified by measuring the maximum absorption signal at 652 nm for oxidized TMB with a wide linear range of 0.5–300.0 nM and a limit of detection (LOD) as low as 0.2 nM. In addition, satisfactory results were obtained for the detection of Ag + in actual water samples. The prepared colorimetric sensor had advantages such as simple operation, cost-effective, fast response, and visualization, and had great potential in detecting toxic Ag + in environmental.
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SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
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2022
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IF 4.831
Xiaoyuan Ma,Shan Xu,Liangyu Li,Zhouping Wang
Here, an aptamer-based SERS method for the detection of Staphylococcus aureus ( S. aureus ) without immobilization using [email protected] NPs/slide as enhanced substrate was constructed. ROX-aptamer of S. aureus was modified on the surface of [email protected] NPs/slide through electrostatic interaction. Based on the specific binding effect of the aptamer to S. aureus , the ROX-aptamer fell off from the surface of the substrate, resulting in a decrease of the SERS signal intensity of the substrate. Under the optimal experimental conditions, a good linear relationship was found between SERS intensity at 1500 cm −1 and the logarithm of concentration of S. aureus in the range of 10 2 cfu/mL-10 7 cfu/mL (y = 6623-796lgx, R 2 = 0.994) with a detection limit of 6 cfu/mL. The selectivity analysis revealed that the method had higher selectivity toward the corresponding target. The results for milk sample using the developed SERS method for the detection of S. aureus were similar to those of the plate counting method. The recovery ratio was from 90.60% to 107.26%, indicating the accuracy and reliability of the developed method. This method eliminates the need for bacterial immobilization and improves the convenience and efficiency of detection.
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DIAMOND AND RELATED MATERIALS
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2022
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IF 3.806
Jixian Ma,Binxia Zhao,Xiaoxiao Fan,Wenjie Wang,Xingliang Chen,Nan Shao,Peiyang Jiang
An efficient Ag/rGO/Bi 2 WO 6 nanocomposite was synthesized by the precipitation-photoreduction method. The resulting Ag/rGO/Bi 2 WO 6 showed excellent photocatalytic activity for the photodegradation of Rhodamine B (RhB), with 15%Ag/rGO/Bi 2 WO 6 photodegrading 96.97% of RhB in 180 min, which was 1.28, 1.09 and 1.05 times higher than that of Bi 2 WO 6 , Ag/rGO, and rGO/Bi 2 WO 6 , respectively. The effect of noble metal Ag's surface plasmon resonance and Schottky barrier , as well as the superior electron transfer ability of rGO , dramatically improved photo-generated electron-hole pair separation and transfer efficiency. In addition, the effects of pollutant concentration, pH, and catalyst dosage on Ag/rGO/Bi 2 WO 6 photocatalytic performance also were explored. Furthermore, the free-radical trapping tests revealed that the primary active radicals in the catalytic system are hole (h + ), superoxide radical (•O 2 − ), and hydroxy radical (•OH). Additionally, after four recycling, the photocatalytic performance of the Ag/rGO/Bi 2 WO 6 composite did not show a significant decline. As a result of this research, the Ag/rGO/Bi 2 WO 6 catalyst, as developed, has a bright potential for environmental purifying.
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TALANTA
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2022
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IF 6.556
Nuo Duan,Tangbin Yao,Changxin Li,Zhouping Wang,Shijia Wu
We designed a SERS-based method to detect β-lactoglobulin (β-Lg), a major allergen of milk, utilizing aptamers to specifically anchor β-Lg. The Au–Ag nanourchins with excellent Raman enhancement effects were prepared and modified with a β-Lg aptamer as the capture substrate. By taking advantage of the hybridization of aptamer and Raman reporter molecule (6-Carboxyl-X-Rhodamine: ROX)-labeled complementary DNA (cDNA), when ROX is close to Au–Ag nanourchins, the SERS signal is enhanced. In the presence of β-Lg, aptamer binding to β-Lg induces the dissociation of ROX-cDNA from Au–Ag nanourchins, thereby decreasing the SERS signal. Under optimal conditions, the present bioassay provides a wide detection range of 10 ng/mL to 1000 ng/mL with a detection limit of 0.07 ng/mL. In addition, the established SERS sensor can selectively and accurately identify β-Lg with recovery rates of 93.25–107.0% in milk samples. It provides great potential as a sensitive and reliable detection method against the growing threat of allergens.
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JOURNAL OF FOOD COMPOSITION AND ANALYSIS
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2022
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IF 4.52
Alberta Osei Barimah,Ping Chen,Limei Yin,Hesham R. El-Seedi,Xiaobo Zou,Zhiming Guo
Detrimental health effects caused by the intake of food contaminated with heavy metals have drawn concerns on effective monitoring using rapid and benign methods. This work presented a novel surface-enhanced Raman scattering (SERS)-based 3-Aminobenzeneboronic acid (ABBA) labeled silver (Ag) nanosensor combined with chemometric algorithms to detect and predict total arsenic (TAs) in acid digested spiked black tea leaves. The sensor recognizes TAs through the partial detachment of ABBA and the chemical formation of As-O-Ag linkage between the TAs and the Ag nanoparticles , which caused a SERS-on signal enhancement effect. SERS combined with competitive adaptive reweighted sampling partial least squares algorithm predicted the TAs with higher correlation coefficient (R p ) results (R p = 0.9750) and a detection limit of 0.0273 µg/g. Good recoveries of 83.84–109.53% and the excellent agreement with the inductively coupled plasma-mass spectrometry method (R 2 = 0.999) revealed this developed rapid method could be deployed for fast-tracking of As in food samples.
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高影响因子
CATALYSIS TODAY
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2022
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IF 6.562
Xiaotong Li,Xufei Shao,Zhisheng Wang,Jinzhu Ma,Hong He
Catalytic decomposition is a promising method of ozone (O 3 ) removal, and Ag-based catalysts have shown excellent O 3 decomposition performance. In this study, the chemical states of Ag species were successfully regulated by varying the loading of Ag and the particle size of α-Fe 2 O 3 supports, and the O 3 decomposition performance of different Ag species (monatomic Ag, Ag clusters (1–2 nm), small Ag nanoparticles (3–5 nm), large Ag nanoparticles (7–12 nm)) was determined. The changes undergone by Ag species after exposure to ozone were characterized in detail, and the ozone decomposition performance of the corresponding Ag species was determined. The terminal and doubly bridging hydroxyl groups on the Fe 2 O 3 support were determined to be the anchoring sites for Ag species. The Ag species and Fe 2 O 3 support are connected through oxygen bridges, forming Ag-O-Fe linkages. This study provides guidance for understanding the mechanism of the interaction between metals and supports and follow-up development of high-efficiency Ag-based catalysts.
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SCIENCE OF THE TOTAL ENVIRONMENT
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2022
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IF 10.753
Siyuan Tang,Da Chen,Guoqiang Guo,Xiameng Li,Changxing Wang,Tingting Li,Gang Wang
Growing global environmental pollution problems challenge the need for converting biomass into an advantageous product. In this paper, Lycium ruthenicum is successfully turned into beneficial green emissive (527 nm) fluorescent nitrogen doping carbon dots (N-CDs) via the hydrothermal treatment for the first time. The horizontal and vertical dimensions of N-CDs are demonstrated to be about 4.5 and 0.73 nm, respectively. The N-CDs possess an extremely stable green fluorescence and quantum yield up to 21.8%. Meaningfully, N-CDs exhibit a good linear relationship with Ag + in the range of 0.7–36 μM, and its detection limit is determined to be 59 nM. The practicability of the fluorescent probe is further validated in lake water and the satisfactory spiked recoveries of Ag + ranges from 98.99% to 104.19%. Besides, based on the sensitive and selective photoluminescence quenching properties, a smartphone-based laboratory device and RGB analysis software are used to directly capture and analyze fluorescence images with a sensitive detection limit of 83 nM for Ag + . This novel sensor based on N-CDs and smartphone provides a reliable way for on-site monitoring of Ag + and expands application prospect in the field of environmental pollution detection.
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