PHYSICAL CHEMISTRY CHEMICAL PHYSICS
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2011
·Vol. 13
·期 32
·14542-14549
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IF 3.454
Kelei Zhuo,Yujuan Chen,Jing Chen,Guangyue Bai,Jianji Wang
Extensive applications of ionic liquids (ILs) may result in their accumulation in the ecological environment and organisms. Although ILs are popularly called “green solvents”, their toxicity, in fact, has been exhibited. Therefore the interaction of ILs with biomolecules is a cutting-edge research subject. Herein, the interactions of 1-butyl-3-methylimidazolium carboxylate ionic liquids ([C4mim][HCOO], [C4mim][CH3COO] and [C4mim][CH3CH2COO]) with glucose in water were studied for their volumetric properties, viscosity, conductivity and NMR spectra. Limiting apparent molar volumes (V0Φ,IL), viscosity B-coefficients, limiting molar conductivities (Λ0) and Walden products (Λ0η0) were evaluated for the ILs in glucose + water solutions. Volumetric interaction parameters were also obtained from the transfer volumes of the ionic liquids. The contributions of the solvent properties (B1) and the ionic liquid–solvent interactions (B2) to the B-coefficient were extracted, together with molar activation energies (Δμ0≠IL) of the ionic liquids for viscous flow of the aqueous glucose + IL solution. In addition, the 13C and 1H NMR spectra of methyl β-D-glucopyranoside and ILs in β-D-glucopyranoside + IL + D2O were studied. The NMR results show that no special and strong interactions were observed between glucopyranoside and the ILs. However, it was confirmed that the H2 on the imidazolium ring has more activity (acidity) than atoms H4 and H5. The macro-properties and their changes were also discussed in terms of the size, structure and solvation of the ILs and glucose.
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POLYMER
·
2012
·
IF 3.438
Changwei Huang,Nianfa Yang,Anlin Zhang,Liwen Yang
Optically active helical poly[( R or S )-3-(9-alkylfluoren-9-yl)propene oxide]s (poly-AFPOs) were used to induce the enantioselective addition of methyllithium to aldehydes. The addition of methyllithium to 4-methoxybenzaldehyde gave the highest enantioselectivity (88% ee) under the inducement of poly-AFPOs. Poly-AFPOs could be recovered simply by pouring the reaction mixture into methanol in the end of the reaction and separating the precipitated polymer via filtration. The recovered poly-AFPOs could be reused for many times to induce the enantioselective addition of methyllithium to aldehyde without losing their enantioselective inducement ability. The investigation of the optical rotation and the MALDI-ToF MS confirmed that, in the enantioselective addition induced by poly-AFPOs, the lithium cation was embedded in the hole of the helical column of poly-AFPOs, leaving the negative methyl ion outside the one-handed helical column. The methyl anion abutted tightly against the helical polymer and acquired a chiral environment. It was this helically chiral environment that resulted in the enantioselective inducement of the addition reaction.
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ANALYTICAL LETTERS
·
2011
·
IF 0.92
Chuanping Wei,Huiqing Zhou,Changbao Chen,Zongchen Li,Jie Zhou
A surface plasmon resonance (SPR)-based detection methodology, which allows the identification and quantification of the plant hormone, 1H-indole-3-acetic acid (IAA) in Peach, Rosa flower, and Crape myrtle bud is described. To achieve high selectivity, a molecularly imprinted monolayer (MIM) was prepared from alkanethiols self-assembled on an SPR sensor chip with preadsorbed template (IAA). The association constant of the MIM to IAA was calculated to be 2.8 × 1011 M−1 by analysis of the SPR wavenumber changes induced by different concentrations of IAA. A good calibration curve was obtained in a low concentration range of IAA. Moreover, the MIM revealed impressive selectivity with the selectivity factors of 1.0, 0.12, and 0.20 for IAA and other related analogues. Compared to the MIM sensor chip, the affinity of the self-assembled monolayer (SAM) control sensor chip for IAA was significantly low. The single SPR sensor decorated with the MIM was used to determine IAA concentrations in peach, Rosa flower, and Crape myrtle bud, and satisfactory results were obtained. Based on a signal to noise ratio of 3, the detection limits were 0.23 pM for Crape myrtle, 0.20 pM for Peach, and 0.32 pM for Rosa. The method showed good recoveries and precision, 95.7% (RSD 0.54%) for Peach, 98.1% (RSD 3.4%) for Rosa, and 98.1% (RSD 2.5%) for Crape myrtle, spiked with 0.4171 µg, respectively. These results indicate that a combination of SPR sensing and the MIM provides a simple, promising alternative method for determining endogenous IAA in plant tissue in a real-time manner.
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JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES
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2017
·
IF 2.603
Hongjuan Li,Ying Liu,Yuetao Yi,Qin miao,Sujing Liu,Feng Zhao,Wei Cong,Chunhua Wang,Chuanhai Xia
In China, Poacynum hendersonii is frequently used as a substitute for Apoacynum venetum L (Luobuma), which is a famous traditional Chinese medicine. Quercetin-3- O -sophoroside and isoquercitrin are two major flavonoids in Poacynum hendersonii leaves. In this work, a suitable method was established for the large-scale preparation of quercetin-3- O -sophoroside (QOS) and isoquercitrin (ISO) from Poacynum hendersonii leaves using macroporous resin combined with Sephadex LH-20 column chromatography. The adsorption/desorption capacities and desorption ratios of six macroporous resins were evaluated using static experiments. The HPD-300 resin had the best adsorption performance because it had the largest surface area, and was selected for further study. Compared with pseudo-first-order and intraparticle diffusion kinetics models, the pseudo-second-order model could better fit the adsorption kinetics of both QOS and ISO on the HPD-300 resin. In addition, the adsorption isotherms of the two compounds on the HPD-300 resin were fitted well to the Langmuir model. Under optimal conditions, the purities of QOS and ISO in the product were increased from 2.16% and 1.26% to 21.34% and 10.70% with recovery yields of 82.1% and 77.3%, respectively. Subsequently, Sephadex LH-20 column chromatography was employed for improving the purities of the two compounds. After separation by Sephadex LH-20 column chromatography, the purities of QOS and ISO achieved 93.5% and 95.6%, respectively.
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ANALYTICAL AND BIOANALYTICAL CHEMISTRY
·
2025
·
IF 3.8
Zhang Shirong,Tan Yuxin,Liu Yilei,Li Yafei,Li Jishun,Zhang Shenglan,Pan Hongcheng
Quantum dots (QDs) have emerged as highly sensitive fluorescent markers for lateral flow immunoassays (LFIAs) due to their excellent fluorescence brightness and photostability. The incorporation of multiple QDs onto a carrier can further enhance detection sensitivity. However, traditional carriers such as polystyrene, while commercially successful, involve complex preparation processes and rely on organic solvents, which can lead to fluorescence quenching and adversely affect detection performance. In this study, we selected isoreticular metal–organic framework-3 (IRMOF-3), characterized by its porous structure, high surface area, and abundant amine functional groups, as the carrier. We synthesized IRMOF-3@CdSe/ZnS composite nanoparticles with an average diameter of 378 ± 46 nm by coupling carboxyl-modified CdSe/ZnS QDs to the IRMOF-3 surface through an aqueous synthesis method. These nanocomposites efficiently loaded a high density of QDs without aggregation, thereby maintaining strong fluorescence intensity. Moreover, the abundant amino and carboxyl groups on their surfaces facilitate efficient antibody conjugation, and the nanoparticles retain excellent water dispersibility after labeling. Utilizing IRMOF-3@CdSe/ZnS composite nanoparticles as immunomarkers, we developed a novel fluorescent LFIA for the detection of interleukin-6 (IL-6), a biomarker associated with various inflammatory and autoimmune diseases. The method achieved a limit of detection for IL-6 as low as 8.6 pg/mL, with relative standard deviations ranging from 2.73% to 6.14% and spiking recoveries between 96.4% and 110.8%. Passing-Bablok regression analysis demonstrated good consistency between our method and commercially available immunochromatography assays. The IRMOF-3@CdSe/ZnS composite nanoparticles, as a novel fluorescent label, exhibit considerable potential for applications in biomedical detection. Graphical abstract
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JOURNAL OF MOLECULAR STRUCTURE
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2025
·
IF 4.7
Wei Ding,Xiaofeng Yuan,Ming Lu,Yuangang Xu
3-Nitro-1-(trinitromethyl)-1 H -pyrazole-4-carboxylic acid ( 4 ) and its corresponding ammonium ( 5 ) and hydroxylammonium ( 6 ) salts were successfully synthesized from 3-amino-1 H -pyrazole-4-carbonitrile. Their structures were characterized by infrared, nuclear magnetic resonance, elemental analysis, and confirmed by single-crystal X-ray diffraction to be triclinic P 1 ¯ ( 4 ), monoclinic C 2 /c ( 5 ) and Cc ( 6 ) Space group with 2, 8, and 4 molecules per unit cell. ADCH charge analysis revealed an uneven electron density distribution across the ring system of 4 , with notably high charge density around two oxygen atoms of the carboxyl group, which facilitates hydrogen bond formation. NICS aromaticity evaluation further confirmed the strong aromatic nature of the product, with an NICS(1)zz value below -20.0 ppm. Remarkably, the hydroxylammonium salt 6 not only retains outstanding detonation properties (detonation velocity D = 8878 m s - ¹, detonation pressure P = 35.60 GPa) but also demonstrates superior mechanical sensitivity (impact sensitivity IS = 12 J, friction sensitivity FS = 200 N). This achieves an optimal balance between high energy and low sensitivity, meeting the design objectives for high-energy insensitive materials. The findings offer valuable insights and experimental support for the molecular design of novel energetic compounds that integrate high energy performance with robust stability.
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ACS Applied Materials & Interfaces
·
2025
·
IF 8.2
Juntao Huang,Saifei Wang,Zhifei Zhang,Mingli Chen,Han Wang,Haihua Huang,Qian Wang,Jigong Hao,Wei Li,Juan Du,Mahesh Kumar Joshi,Peng Fu
Ceramic dielectric capacitors have gained significant attention due to their ultrahigh power density, current density, and ultrafast charge–discharge speed. However, their potential applications have been limited by their relatively low energy storage density. Researchers have employed various approaches to enhance their energy storage density. In this study, (1 – x)(Bi0.5Na0.5)0.7Sr0.3TiO3–xCa(Mg1/3Ta2/3)O3 ceramics were prepared via a solid-phase reaction, and the effect of their structure on the energy storage properties was investigated. The results indicate that the introduction of Ca(Mg1/3Ta2/3)O3 significantly alters the multiscale structures of the (Bi0.5Na0.5)0.7Sr0.3TiO3 ceramic, including the transformation from the T-phase to the C-phase, refinement of ceramic grains, and the formation of polar nanoregions (PNRs), accompanied by an increase in the bandgap and relaxation degree. These structural changes collectively contributed to the improved overall energy storage properties of the modified ceramics. Notably, the 0.92(Bi0.5Na0.5)0.7Sr0.3TiO3–0.08Ca(Mg1/3Ta2/3)O3 ceramic demonstrated a recoverable energy storage density (Wrec) of 8.37 J/cm3 with an energy storage efficiency (η) of 87.7% at an electric field of 530 kV/cm. It also exhibited good temperature stability (25–120 °C), frequency stability (1–100 Hz), and fatigue stability (1–105). Furthermore, it displayed exceptional charge and discharge properties, with the discharge energy density (WD), discharge time (t0.9), current density (CD), and power density (PD) attaining 4.06 J/cm3, 35.2 ns, 2143.28 A/cm2, and 460.71 MW/cm3, respectively. These findings suggest that modified (1 – x)(Bi0.5Na0.5)0.7Sr0.3TiO3–xCa(Mg1/3Ta2/3)O3 ceramics are promising candidates for high-power pulsed electronic systems.
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Nano Energy
·
2021
·
IF 17.881
Guijia Cui,Qingyu Dong,Zhuangzhou Wang,Xiao-Zhen Liao,Siqi Yuan,Meidan Jiang,Yanbin Shen,Hong Wang,Haiying Che,Yu-Shi He,Zi-Feng Ma
NASICON-type (Na super ionic conductor) Na 4 VMn(PO 4 ) 3 (NVMP) cathode material has attracted increasing attention due to its higher sodium de-/intercalation voltage, lower cost and greener resources compared with Na 3 V 2 (PO 4 ) 3 . However, the poor electronic conductivity limits the exploitation of its electrochemical performance. In this work, we achieved an ultrahigh rate capable and long cycle life NVMP/C-rGO composite using the simple and scalable spray-drying technique, in which low-fraction rGO nanosheets (2.14 wt%) highly dispersed and bridged the carbon shelled NVMP nanoparticles to form an effective electron conductive network. Benefiting from this favorable nano-architecture, the elaborately designed NVMP/C-rGO composite exhibited excellent performance as cathode in sodium ion batteries, delivering reversible capacities of 105.5 mA h g −1 at 1 C (1 C = 110 mA h g −1 ) and 102.6 mA h g −1 at 50 C with capacity retention of 90.6% (1 C) and 80.4% (50 C) over 500 cycles, respectively. This is the highest rate performance for Na 4 VMn(PO 4 ) 3 materials reported so far. This work provides a practicable tactic for fabricating advanced polyanion-type cathode materials which can be commercially scale up for sodium energy storage.
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JOURNAL OF COLLOID AND INTERFACE SCIENCE
·
2014
·
IF 3.552
Qiang Zhang,Qinfu Zhao,Ying Zhang,Ning Han,Liang Hu,Chen Zhang,Tongying Jiang,Siling Wang
3-D ordered macroporous (3DOM) materials were customized for BSA adsorption and further oral immunization. These carriers have a high adsorption capacity and our customized carrier showed a distinctive double-plateau adsorption behavior. Different BSA release rates (between the two plateaus) could be obtained by adjusting the ratio of the protein adsorbed on the internal surface and the external surface. This suggests that the release pattern was determined by the adsorption state. One benefit is that the same carrier could have different release profiles making it possible to study the relationship between the release behavior and adjuvant effects without any distractions. Compared with free BSA alone, a significantly higher level of serum IgG, IgA induced by BSA/3DOM was observed and the release profile had an effect on the immunity. The IgG1 and IgG2a titers suggesting that both the Th1 and Th2 mediated immune response were induced. Therefore, this research could help in the development of a novel inorganic oral adjuvant and provide a new avenue for the administration of oral vaccine.
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Algal Research-Biomass Biofuels and Bioproducts
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2019
·
IF 3.723
Linfei Huang,Lihua Yu,Zhongze Li,Yanhua Li,Kang-sup Yoon,Qiang Hu,Li Yuan,Danxiang Han
The plastidial lysophosphatidic acid acyltransferase of the unicellular green alga Chlamydomonas reinhardtii (CrLPAAT1) is a key enzyme involved in triacylglycerol biosynthesis . However, research on the biochemical characteristics of CrLPAAT1 has been impeded by its membrane-bound nature. In this study, the recombinant CrLPAAT1 was purified in a soluble form and was utilized for comprehensive biochemical characterization. The recombinant CrLPAAT1 favors the conditions of pH 6.5–7.5, 30 °C and the presence of magnesium ion in vitro . Similar with the CrLPAAT1 associated with the membranes, the purified CrLPAAT1 prefers to utilize C16:0-CoA over other acyl donors, whereas it showed broader substrate selectivity than the membrane-bound enzyme. By comparing the wild-type CrLPAAT1 and a transmembrane domain-truncated enzyme, it was uncovered in this study that the two transmembrane domains of CrLPAAT1 are involved in shaping its substrate preference for C16:0-CoA. Additionally, CrLPAAT1 was found to be interacting with the water-soluble plastidial glycerol-3-phosphate acyltransferase (CrGAPTcl) via its two transmembrane domains in vitro . The interaction between CrLPAAT1 and CrGPATcl can be negatively regulated by both the acyl-CoAs and lysophosphatidic acid in a dosage-dependent manner. Such a regulation pattern may represent a novel mechanism adopted by algal cells to control lipid metabolism homeostasis under various environmental conditions.
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Inorganic Chemistry Frontiers
·
2025
·Vol. 12
·期 23
·7566-7572
·
IF 6.4
Xiaodong Zhang,Bohui Xu,Deshuai Xiao,Xinyuan Zhang,Pifu Gong,Zheshuai Lin
Ultraviolet (UV) nonlinear optical (NLO) materials are critical for laser frequency conversion to extend wavelength ranges. Sulfates have emerged as a promising family of UV NLO materials, yet their NLO performance is constrained by the low optical anisotropy of the constituent [SO4]2− groups. In this study, we investigate the [C6H5SO3]− group, formed by substituting a ligand of the non-π-conjugated [SO4]2− unit with a π-conjugated benzene ring, and demonstrate that this group has a strong second harmonic generation (SHG) response and large birefringence. Leveraging this optimized structural unit, we successfully synthesize the first UV NLO benzenesulfonate, Y(C6H5SO3)3·9H2O. This compound exhibits enhanced UV optical properties, including a short cutoff edge of 280 nm, a relatively large SHG efficiency (0.8 × KDP), and a large birefringence of 0.16 at 1064 nm. This work not only presents Y(C6H5SO3)3·9H2O as a competitive UV NLO material, but also highlights the [C6H5SO3]− group as a highly effective structural motif for the future development of advanced UV NLO materials.
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JOURNAL OF CHEMICAL AND ENGINEERING DATA
·
2025
·
IF 2.1
Zhe Wu,Zhe Xue,Shaolan Zhuang,Yire Ma,Xiaofei Tang,Pengqi Hou,Qunsheng Li,Zhongqi Ren,Hongkang Zhao
The solubility of 3-methoxycinnamic acid was determined in nine pure solvents (methanol to ethyl acetate) and ethanol–ethyl acetate binary mixtures (293.15–333.15 K). Results demonstrate positive temperature dependence in all systems, with maximum solubility in binary solvent at ethanol volume fraction of 0.3, while benzene exhibited the lowest solubility. Solid–liquid equilibrium (SLE) data were correlated using five thermodynamic models (modified Apelblat, Van’t Hoff, Wilson, NRTL, UNIQUAC). The modified Apelblat equation showed superior accuracy for both solvent systems. KAT-LSER analysis revealed solvent hydrogen-bond acidity (α), basicity (β), and cohesive energy density (CED) (δH) as dominant molecular descriptors. Thermodynamic parameters (ΔGmix < 0) confirmed spontaneous dissolution, with enthalpy–entropy compensation revealed by Gibbs energy deconvolution. The obtained solubility and thermodynamic data may be useful for the design and optimization of crystallization processes of 3-methoxycinnamic acid.
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危险品化学品经营许可证（带存储）