BIOSENSORS & BIOELECTRONICS
·
2018
·
IF 8.173
Liang Tian,Jinxu Qi,Olayinka Oderinde,Chen Yao,Wei Song,Yihong Wang
Enzyme mimics have been developed for bioassay of nucleic acids , with some of them involving complicated labeling. Herein, we report a label-free bioassay for ultrasensitive electronic determination of microRNA at an ultralow concentration based on target-triggered long-range self-assembly DNA-based hybridization chain reaction (HCR) protocol coupled with bienzyme mimics synergistic catalysis strategy. In this work, a planar intercalation molecule, copper (II) complex, is applied for the first time as a small molecule enzyme mimic as well as intercalation molecule in microRNA biosensor for signal amplification . Fe 3 O 4 nanozyme were used as a separate and enriched target under magnetic field, and also in combination with HCR protocol detected in 3,3’,5,5’-tetramethylbenzidine+hydrogen peroxide (TMB+H 2 O 2 ) system to improve the sensitivity of the biosensor. Under optimal conditions, these strategies present good electrochemical behaviors for the detection of microRNA with a wide range from 100 aM to 100 nM and at relatively low detection limit of 33 aM This remarkable sensitivity can make this proposed approach a promising scheme for development of next-generation microRNA sensors without the need of enzyme labeling or fluorophore labeling.
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PubMed
高影响因子
TALANTA
·
2017
·
IF 4.162
Jiebing Jiang,Xueni Sun,Yan Li,Chunhui Deng,Gengli Duan
Metal ions differed greatly in affinity towards phosphopeptides, and thus it is essential to systematically compare the phosphopeptides enrichment ability of different metal ions usually used in the IMAC techniques. In this work, for the first time, eight metal ions, including Nb 5+ , Ti 4+ , Zr 4+ , Ga 3+ , Y 3+ , In 3+ , Ce 4+ , Fe 3+ , were immobilized on the polydopamine (PDA)-coated Fe 3 O 4 (denoted as Fe 3 O 4 @PDA-M n+ ), and systematically compared by the real biosamples, in addition to standard phosphopeptides. Fe 3 O 4 microspheres were synthesized via the solvothermal reaction, followed by self-polymerization of dopamine on the surface. Then through taking advantage of the hydroxyl and amino group of PDA, the eight metal ions were easily adhered to the surface of Fe 3 O 4 @PDA. After characterization, the resultant Fe 3 O 4 @PDA-M n+ microspheres were applied to phosphopeptides enrichment based on the binding affinity between metal ions and phosphopeptides. According to the results, different metal ions presented diverse phosphopeptides enrichment efficiency in terms of selectivity, sensitivity and the enrichment ability from real complex samples, and Fe 3 O 4 @PDA-Nb 5+ and Fe 3 O 4 @PDA-Ti 4+ showed obvious advantages of the phosphopeptides enrichment effect after the comparison. This systematic comparison may provide certain reference for the use and development of IMAC materials in the future.
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高影响因子
Catalysis Science & Technology
·
2013
·Vol. 3
·期 8
·2104-2112
·
IF 3.753
Shuguo Wang,Zehui Zhang,Bing Liu,Jinlin Li
In this study, a magnetically-recoverable catalyst (Fe3O4@SiO2-HPW) was prepared by the application of phosphotungstic acid (HPW) supported on silica-coated Fe3O4 nanoparticles. The prepared samples were characterized by XRD, TEM, FT-IR, and N2-adsorption–desorption isotherms. The content of W in Fe3O4@SiO2-HPW was measured by inductively coupled plasma atomic emission spectroscopy (ICP-AES) and its surface acidity was determined by a potentiometric titration with n-butylamine. Fe3O4@SiO2-HPW showed an excellent catalytic activity for the synthesis of EMF from HMF and fructose. Under optimal reaction conditions, EMF was obtained in a high yield of 83.6% by the etherification of 5-hydroxymethylfurfural. EMF could also be synthesized directly from fructose in a yield of 54.8% via a one-pot reaction strategy. After reaction, the catalyst Fe3O4@SiO2-HPW could be easily separated from the reaction mixture with an external magnetic field, and it could be reused at least five times without any loss of its catalytic activity.
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高影响因子
NEW JOURNAL OF CHEMISTRY
·
2022
·Vol. 46
·期 18
·8534-8544
·
IF 3.925
Ruowei Lu,Cuijuan Wang,Yanxia Chen,Lichuan Tan,Peng Wang,Siwen Feng
Adsorption and Fenton catalysis technologies have been widely used to treat wastewater. Herein, Zr-MOF composites are synthesized with Mn-doped magnetic hierarchical porosity and ionic liquid (IL) post-functionalization (MFC@Mn-NH2-UiO-66@IL). The characterization of the composite shows that the MOF we synthesized is laminar and porous, which promotes the adsorption process and subsequent H2O2 decomposition catalysis. Electrostatic interactions, hydrogen bonds, and π–π stacking interactions between [BMIM][PF6] and methylene blue (MB) greatly improve the adsorption performance. Subsequently, H2O2 is rapidly decomposed in a Zr-MOF and Fe3O4 system to produce ˙OH for the oxidative decomposition of MB. Zr plays an electron transfer role in the catalytic reaction. The MFC@Mn-NH2-UiO-66@IL material has a high adsorption capacity for aqueous MB solutions. In combination with the subsequent Fenton-like oxidation reaction, a removal efficiency of 98% is achieved in 90 min. We believe that our work has essential impact in the field of wastewater treatment based on the advantages of the MOF's dual function in degrading pollutants in water.
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高影响因子
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
·
2018
·Vol. 25
·期 18
·17310-17320
·
IF 2.8
Pu Shengyan,Xue Shengyang,Yang Zeng,Hou Yaqi,Zhu Rongxin,Chu Wei
A superparamagnetic graphene oxide (GO)/Fe 3 O 4 nanocomposite (MGO) was prepared by a facile in situ co-precipitation strategy, resulting in a prospective material for the application of graphene oxide in wastewater treatment. MGO was characterized by scanning electron microscopy (SEM), transmission electron microscopy (TEM), x-ray diffraction (XRD), and Fourier transform infrared spectroscopy (FTIR). The prepared adsorbent showed a high adsorption efficiency relevant to the purification of dye-contaminated wastewater and could be readily magnetically separated. The maximum adsorption capacity was ca. 546.45 mg g −1 for the common cationic dye methylene blue (MB) and ca. 628.93 mg g −1 for the anionic dye Congo red (CR). The adsorption processes fit the pseudo-second-order kinetic model well, which revealed that these processes may involve the chemical interaction between adsorbate and adsorbent. The thermodynamic parameters indicated that the adsorption reaction was an endothermic and spontaneous process. Furthermore, the prepared magnetic adsorbent had a wide effective pH range from 5 to 11 and showed good stability after five reuse cycles. The synthetic MGO showed great potential as a promising adsorbent for organic contaminant removal in wastewater treatment.
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高影响因子
RSC Advances
·
2017
·Vol. 7
·期 60
·37929-37937
·
IF 3.108
Yang Luo,Sinan Du,Wei Zhang,Zhengfang Liao,Fang Zuo,Shengtao Yang
Core@shell structures of Fe3O4@Mn2+-doped NaYF4:Yb/Tm nanoparticles (NPs) with multifunctional properties were prepared using a hydrothermal route with a seed-growth procedure. The effect of Mn2+ ions on the phase, shape, and upconversion luminescence (UCL) of Fe3O4@Mn2+-doped NaYF4:Yb/Tm NPs was explored using X-ray diffraction, transmission electron microscopy, dynamic light scattering, and photoluminescence spectroscopy. Furthermore, hydrophobic to hydrophilic surface modification of the Fe3O4@Mn2+-doped NaYF4:Yb/Tm NPs was achieved by coating the NPs with an amphiphilic polymer (poly(maleic anhydride-alt-1-octadecene) (C18PMH)) modified with amine-functionalized methyl ether poly(ethylene glycol). Then, the NIR-to-NIR UCL ascribed to the Tm3+ ions, T1-weighted MRI ascribed to the Mn2+ ions, and T2-weighted MRI ascribed to the Fe3O4 core of the hydrophilic Fe3O4@Mn2+-doped NaYF4:Yb/Tm NPs were evaluated. The results indicate that Mn2+ doping is an effective method to control the size/shape and improve the UCL intensity of Fe3O4@Mn2+-doped NaYF4:Yb/Tm NPs, which are promising as imaging agents for NIR-to-NIR UCL and T1/T2-weighted MRI in biomedical research.
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高影响因子
MICROCHIMICA ACTA
·
2019
·Vol. 186
·期 8
·1-9
·
IF 5.479
Nian Qixun,Wang Xuesheng,Wang Manman,Zuo Guifu
Magnetic carbon nitride composites were synthesized via a solvothermal reaction and developed as an effective adsorbent for magnetic solid-phase extraction of trace hydroxylated polycyclic aromatic hydrocarbons (OH-PAHs) from urine samples prior to their determination by HPLC. The sorbent was characterized by Fourier transform infrared spectrometry, X-ray diffractometry, scanning electron microscopy, vibrating sample magnetometry and solvent stability experiments. The adsorption of hydroxy-PAHs is better by a factor or 20 to 49 compared to bare Fe 3 O 4 and comparable that of a commercial C 18 sorbent. The adsorbent amount, adsorption time and eluting solvent and volume were optimized. The complete extraction for the OH-PAHs at a level of 40 ng·mL −1 and by using 4 mg sorbent is completed within 3 min. With an enzymatic hydrolyzed urine sample loading volume of 2 mL, enhancement factors in the range of 9–10, and a limit of detection (at S / N = 3) of 0.08 ng·mL −1 were achieved. The method showed a linear response in the 0.25–250 ng·mL −1 hydroxy-PAH concentration range, and intra-day and inter-day precisions are 1.5–7.7% and 2.2–8.7%, respectively. The recovery from spiked urine samples ranged from 90.1% to 102%. The sorbent was stable over 10 successive cycles of extraction/desorption of urine sample without significant loss of extraction efficiency. The method was successfully applied for the determination of OH-PAHs in urine samples of smoking volunteers.
Schematic presentation of the preparation of graphitic carbon nitride (g-C 3 N 4 )/magnetite (Fe 3 O 4 ) using a solvothermal reaction, and application for magnetic solid-phase extraction of three trace hydroxy polycyclic aromatic hydrocarbons (OH-PAHs) in urine samples of smoking volunteers.
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高影响因子
Journal of Environmental Sciences
·
2023
·
IF 6.9
Ting He,Jie Sun,Liangwei Deng,Jialin Ming,Changwei Hu
Due to its high efficiency, Fe(II)-based catalytic oxidation has been one of the most popular types of technology for treating growing organic pollutants. A lot of chemical Fe sludge along with various refractory pollutants was concomitantly produced, which may cause secondary environmental problems without proper disposal. We here innovatively proposed an effective method of achieving zero Fe sludge, reusing Fe resources (Fe recovery = 100%) and advancing organics removal (final TOC removal > 70%) simultaneously, based on the in situ formation of magnetic Ca-Fe layered double hydroxide (Fe 3 O 4 @CaFe-LDH) nano-material. Cations (Ca 2+ and Fe 3+ ) concentration (≥ 30 mmol/L) and their molar ratio (Ca:Fe ≥ 1.75) were crucial to the success of the method. Extrinsic nano Fe 3 O 4 was designed to be involved in the Fe(II)-catalytic wastewater treatment process, and was modified by oxidation intermediates/products (especially those with COO − structure), which promoted the co-precipitation of Ca 2+ (originated from Ca(OH) 2 added after oxidation process) and by-produced Fe 3+ cations on its surface to in situ generate core-shell Fe 3 O 4 @CaFe-LDH. The oxidation products were further removed during Fe 3 O 4 @CaFe-LDH material formation via intercalation and adsorption. This method was applicable to many kinds of organic wastewater, such as bisphenol A, methyl orange, humics, and biogas slurry. The prepared magnetic and hierarchical CaFe-LDH nanocomposite material showed comparable application performance to the recently reported CaFe-LDHs. This work provides a new strategy for efficiently enhancing the efficiency and economy of Fe(II)-catalyzed oxidative wastewater treatment by producing high value-added LDHs materials.
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高影响因子
APPLIED ORGANOMETALLIC CHEMISTRY
·
2026
·Vol. 40
·期 4
·e70546
·
IF 4.3
Hangyu Zhang,Shuang Yao,Zhiwen Jiang,Lei Xie,Zixia Lin,Guoliang Dai,Juanhong Li,Xin Liu,Feng Liu
In Fenton-like reactions, the catalysts generally have an inherent drawback: Their active centers are prone to being lost from the catalyst supports, leading to a continuous decline in catalytic efficiency and causing secondary pollution. To address this issue, two catalysts, including Fe 3 O 4 @UiO-66(Zr) and Fe 3 O 4 @UiO-66(Zr)-COOH, were prepared in this study by confining Fe 3 O 4 active centers within the pores of UiO-66(Zr) and grafting -COOH groups to enhance metal coordination interactions. The Fe 3 O 4 @UiO-66(Zr)-COOH achieved 99% removal efficiency of carbamazepine within 5 min under the conditions of pH = 3.0, 40 mM H 2 O 2 , 20 mg·L −1 carbamazepine, and 2 g·L −1 catalyst. This efficiency far exceeded that of Fe 3 O 4 @UiO-66(Zr) (61.5%) and was 3.96 times higher than that of the Fenton-like system. The rapid degradation of CBZ was realized through stabilized active centers and enhanced metal coordination. In this work, the iron-based material was found to enhance the coordination between Fe and Zr. As confirmed by quenching experiments, electron spin resonance, electrochemical tests, and density functional theory calculations, ·OH and 1 O 2 were identified as the dominant active species. The -COOH, acting as electron bridges, enhanced electrical conductivity and reduced electron transfer barriers, thereby facilitating faster charge transfer processes. In addition, it was demonstrated by six cycles of experiments that Fe 3 O 4 @UiO-66(Zr)-COOH possessed excellent stability. It was also shown by the characterization of the catalyst after the cycles that both the performance and morphology of the composite material could be maintained unchanged.
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高影响因子
FOOD CHEMISTRY
·
2026
·
IF 10.4
Liyu Hou,Haodong Wang,Lan Sun,Xinyuan Wang,Zhongping Huang,Huijun Liu,Jing Yu
4.71–5.19 μg/box and 1.27–1.40 μg/box were detected for the migrated PS MPs and NPs. • Hydrophilic iron oxide nanoparticle was used to capture polystyrene nanoplastics. • Adsorption mechanism includes hydrogen bonding, coordination, electrostatic interaction. • Quantification of PS MPs and PS NPs from lunch boxes by Py-GC/MS. • The aging effect causing the decomposition of PS MPs into PS NPs. In this study, 1 μm glass fiber membranes were used to enrich polystyrene microplastics (PS MPs), and then hydrophilic iron oxide nanoparticle (n-Fe 3 O 4 ) was used to capture the residual polystyrene nanoplastics (PS NPs), primarily through hydrogen bonding, coordination, and electrostatic interactions. MPs on membranes and NPs captured by n-Fe 3 O 4 were respectively determined by pyrolysis-gas chromatography/mass spectrometry (Py-GC/MS). The method was verified by adding PS MNPs standard to ultrapure water. The detection limit of this method was 0.16 μg/cup for PS MPs and 0.03 μg/cup for PS NPs. The absolute recovery rates of MPs and NPs were 99 ± 2% and 89 ± 3%, respectively. The test results of three batches of PS lunch boxes showed that the content of PS MPs attached on surfaces was 6.79–12.30 μg/box, and the content of PS NPs was 0.51–0.96 μg/box. The migrated PS MPs and PS NPs were 4.71–5.19 μg/box and 1.27–1.40 μg/box respectively.
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PubMed
高影响因子
SENSORS AND ACTUATORS B-CHEMICAL
·
2025
·
IF 7.7
Jian Chen,Jiaying Yang,Yanbin Lu,Zhiyuan Dai,Huan Li
Okadaic acid (OA), a diarrhetic shellfish toxin, poses severe health risks to humans and causes substantial economic losses in aquaculture, creating an urgent need for rapid, sensitive, and field-deployable detection technologies for tracing its contamination in shellfish. Herein, we proposed a surface-enhanced Raman scattering (SERS) sensing method for OA in shellfish. The system was constructed by integrating Raman-active aptamer-modified gold/magnetic nanohybrids (Apt-Au/Fe 3 O 4 NHs) with a complementary sequence-modified silver nanoparticle-functionalized bacterial cellulose film (CS-Ag NPs@BC-film). Upon the introduction of OA, it competitively bound with the Apt, leaving the CS-Ag NPs@BC-film after magnetic separation, thereby inducing a reduction in the Raman signal. Sensitive quantification of OA was achieved by measuring the difference in the Raman signal, achieving a detection limit as low as 2.82 × 10 −2 nM (S/N = 3). Analysis of the spiked real samples demonstrated good accuracy and precision of the method. Compared with commercial ELISA kits, the method presented with comparable detection results while offering simplified operational workflows. These findings highlight its potential as a practical tool for monitoring hazardous contaminants in aquatic environments and ensuring seafood safety.
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高影响因子
MICROCHEMICAL JOURNAL
·
2019
·
IF 3.206
Lu Huang,Wanxiang Yu,Xiaojing Guo,Yejing Huang,Qing Zhou,Haiyun Zhai
A new technique for simultaneous determination of tetracycline (TC), chlortetracycline (CTC), doxycycline (DC) in egg samples was developed by using radiant-type multi-molecularly imprinted solid-phase extraction (MISPE)-PDMS/glass array chip coated magnetic graphene oxide (Fe 3 O 4 /GO). Three kinds of molecularly imprinted polymers coated Fe 3 O 4 /GO (Fe 3 O 4 /GO-MIPs) were synthesized by in situ polymerization using TC, CTC and DC as single templates, respectively. The Fe 3 O 4 /GO-MISPE monolithic columns exhibited high affinity and specificity to TC, CTC and DC, as detected by high performance liquid chromatography coupled with fluorescence detection. Moreover, the radiant-type array extraction chip showed excellent adsorption capacity and particular selectivity to TC, CTC and DC, with the enrichment factors reaching 86–104 folds. Fe 3 O 4 /GO-MIPs were tested by scanning electron microscopy and Fourier transform-infrared spectroscopy. The limit of detection for TC, CTC and DC was 3.0–5.5 μg kg − 1 . Therefore, the chip-based imprinted monolithic array columns are promising for facile extraction of TC, CTC and DC from egg samples.
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高影响因子
危险品化学品经营许可证（带存储）