MACROMOLECULAR RESEARCH
·
2018
·Vol. 26
·期 4
·365-373
·
IF 1.767
Ling Lei,Li Jinhui,Zhang Guoping,Sun Rong,Wong Ching-Ping
Self-healing polymeric materials have attracted extensively interests due to the ability to heal the damage autonomously. The self-healing systems based on dynamic disulfide bonds have been the most promising due to the efficient healing capacity at a mild condition. However, it is still of great challenge for designing the polymer with excellent mechanical and self-healing property by a simple synthetic route. Herein, a novel series of self-healing linear polyurethanes with the disulfide linkage as the grafting point were developed. The synthetic polymers all exhibited excellent mechanical properties (breaking strength and elongation at break were as much as 31.91 MPa and 1156% for PU-A). Meanwhile, the effects of different ratios of soft/hard segments on the mechanical properties and healing efficiencies have been investigated by stress-strain tests. The results showed that with the increase of soft segments contents, the breaking strength and elongation at break of the polymer improved significantly, while the healing efficiency and Young’s modulus showed a declining trend. The self-healing polyurethane can quickly restore its over 90% of mechanical property after healing at moderate temperature for 10 min. The cyclic tensile tests also showed the dissipated efficiencies and self-recovery abilities of the polymers. Finally, the recovery capability tests verified the shape memory effect in the polymers, which can replace an external force to accelerate the healing process.
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高影响因子
Journal of Food Measurement and Characterization
·
2024
·Vol. 18
·期 5
·3569-3576
·
IF 2.9
Liu Shanshan,Zhang Yu
This study analyzed the anthocyanin content and antioxidant properties of five mulberry ( Morus spp. ) varieties, including black ( M. nigra ), red ( M. rubra ) and white ( M. alba ) types. Anthocyanins were extracted and analyzed using HPLC–MS, which revealed four major pigments: cyanidin-3-glucoside, cyanidin-3-rutinoside, cyanidin-3,5-diglucoside and pelargonidin-3-glucoside. Total anthocyanins were significantly higher in black mulberries Bom irangi (185 mg/100 g) and Kalmi (158 mg/100 g) compared to 28–60 mg/100 g in other varieties, consistent with their dark fruit color. Electrochemical analysis by cyclic voltammetry showed oxidation peak potentials (E pa ) of key anthocyanins: + 368 mV for cyanidin; + 830 mV for cyanidin-3-glucoside; and + 912 mV for pelargonidin-3-glucoside. Lower E pa indicates easier oxidation and greater antioxidant activity. DPPH radical scavenging assays revealed strongest potency for Bom irangi (EC50 42 μg/mL) and Kalmi (EC50 58 μg/mL), again due to high anthocyanin levels. Further, a negative correlation (R 2 = 0.923) was demonstrated between E pa values and EC50, proving excellent predictive ability of electrochemical data for estimating antioxidant capacity. Cyanidin with lowest E pa (+ 368 mV) and highest hydroxylation exhibited strongest activity (EC50 35 μg/mL). Overall, the study successfully demonstrated the antioxidant potential of mulberry anthocyanins, especially from black varieties, using advanced analytical strategies.
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MONATSHEFTE FUR CHEMIE
·
2023
·Vol. 154
·期 10
·1189-1195
·
IF 1.8
Wang Peng,Shi Huibing,Feng Baolin,Zhao Deming,Wu Haigang
The Ru-catalyzed highly selective alkoxycarbonylation of allenes with aliphatic alcohols (also as solvent) allow to produce useful α , β -unsaturated esters in good to excellent yields at 70 °C. Efficient regioselectivity could be controlled in the presence of N-ligands while the P-ligands had no influence on the conversion of substrates and the chemo/regioselectivity of target products. By involving N-ligand 4,7-dimethyl-1,10-phenanthroline in the catalytic system, α , β -unsaturated esters were obtained with high conversion and chemo/regioselectivity (conversion up to 99%, chemical selectivity up to 99%, regioselectivity of branched ester/linear ester up to 89/11). Graphical abstract
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Frontiers of Environmental Science & Engineering
·
2025
·Vol. 19
·期 4
·1-13
·
IF 6.4
Jiang Linke,Li Yong,Shi Shuiqin,Yan Junmei,Chi Lianbao,Liu Hui,Feng Mingbao
Chlorinating wastewater before it is released into surface water can change the fate of organic pollutants. This transformation is influenced by chlorine residues, bromine-containing wastewater, and solar radiation. Losartan (LOS), one of the earliest sartan antihypertensive drugs produced, is used worldwide and has been found in the environment. However, its transformation mechanisms and environmental risks have not been systematically investigated. This research presents the degradation kinetics, transformation products, and environmental risks of LOS in different scenarios. The results revealed that k app, HClO (LOS) ranged from 0.47 to 8.30 L/(mol·s) at pH 5.0–8.0. The k app, HBrO (LOS) values at pH 5.0–8.0 ranged from 8.38 × 10 3 to 1.55 × 10 5 L/(mol·s), revealing a faster bromination reaction than chlorination. LOS degrades through direct photolysis, carbonate radicals (CO 3 / •− ), and singlet oxygen ( 1 O 2 ) under sunlight exposure. The solar/chlorination process accelerates the reaction rate through radical activity. In addition, chlorination and bromination resulted in halogen addition to the aromatic ring, whereas hydroxylation, hydrogen abstraction, demethylation, ring opening, and hydrolysis reactions were observed across all processes. Some products exhibit high biodegradation resistance and high toxicity, potentially threatening the aquatic environment. This study aims to enhance our understanding of the environmental behavior and resulting risks of LOS by exploring its environmental fate through various transformation processes.
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高影响因子
JOURNAL OF SOLID STATE ELECTROCHEMISTRY
·
2024
·Vol. 28
·期 8
·2959-2971
·
IF 2.6
Gao Yali,Pang Wanyu,Chang Xile,Hu Zhiyong,Hu Tuoping,Ma Xuemei
Baicalin (Bn) is one of the flavonoids with various biological activities, and its accurate determination is of great significance to clinical medicine. The new “MOF-on-MOF” materials have a broad application prospect. ZIF-67 and MIL-101(Fe) are typical metal–organic frame (MOF) materials, which have the advantages of flexible structure, large specific surface area, large porosity, and adjustable pore size. In this paper, a disposable and sensitive Bn electrochemical sensor based on ZIF-67/MIL-101(Fe) composite modified carbon paper (CP) electrode was developed for the first time. The sensing nanomaterials were characterized by scanning electron microscopy (SEM), transmission electron microscopy (TEM), X-ray diffraction spectroscopy (XRD), and X-ray photoelectron spectroscopy (XPS). Cyclic voltammetry (CV) was used to evaluate the electrochemical behavior of Bn on different modified electrodes. The results showed that ZIF-67/MIL-101(Fe)/CP exhibited a well-defined redox peak compared with bare CP, ZIF-67/CP, and MIL-101(Fe)/CP, which was attributed to the synergistic effect of ZIF-67 and MIL-101(Fe). Under optimal conditions, the electrochemical sensor was able to quantify Bn in the ranges of 0.01 ~ 3 µM and 3 ~ 6 µM with a detection limit (LOD) as low as 0.009 µM (S/N = 3). In addition, the sensor was successfully used for the quantitative analysis of Bn in Dual yellow oral liquid with reliable results.
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JOURNAL OF NANOBIOTECHNOLOGY
·
2023
·Vol. 21
·期 1
·1-15
·
IF 10.2
Luo Tingting,Jiang Mingyang,Cheng Ziqiang,Lin Yuntao,Chen Yuling,Zhang Zhenyu,Zhou Jian,Zhou Wenhua,Yu Xue-Feng,Li Shuchun,Geng Shengyong,Yang Hongyu
As a common tumor with high incidence, osteosarcoma possesses extremely poor prognosis and high mortality. Improving the survival of osteosarcoma patients is still a great challenge due to the precipice of advancement in treatment. In this study, a combination strategy of gene therapy and photothermal therapy (PTT) is developed for efficient treatment of osteosarcoma. Two-dimensional (2D) FePS 3 nanosheets are synthesized and functionalized by poly-L-lysine-PEG-folic acid (PPF) to fabricate a multifunctional nanoplatform (FePS@PPF) for further loading microRNAs inhibitor, miR-19a inhibitor (anti-miR-19a). The photothermal conversion efficiency of FePS@PPF is up to 47.1% under irradiation by 1064 nm laser. In vitro study shows that anti-miR-19a can be efficiently internalized into osteosarcoma cells through the protection and delivery of FePS@PPF nanaocarrier, which induces up-regulation of PTEN protein and down-regulation p-AKT protein. After intravenous injection, the FePS@PPF nanoplatform specifically accumulates to tumor site of osteosarcoma-bearing mice. The in vitro and in vivo investigations reveal that the combined PTT-gene therapy displays most significant tumor ablation compared with monotherapy. More importantly, the good biodegradability promotes FePS@PPF to be cleared from body avoiding potential toxicity of long-term retention. Our work not only develops a combined strategy of NIR-II PTT and gene therapy mediated by anti-miR-19a/FePS@PPF but also provides insights into the design and applications of other nanotherapeutic platforms.
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ENVIRONMENTAL MONITORING AND ASSESSMENT
·
2024
·Vol. 196
·期 2
·1-18
·
IF 2.9
Yue Xiupeng,Shan Yongping,Zhang Yaping,Jiao Wentao,Shen Kai
The transfer of heat and contaminants by alternating current (AC) and the removal mechanism of polycyclic aromatic hydrocarbons (PAHs) in electrical resistance heating (ERH) need further study. The main factors affecting heat transfer and water evaporation in the ERH experiment were studied, and the desorption efficiency, temporal and spatial distribution and kinetic behavior under various conditions were analyzed. The results suggested that moisture content was a necessary condition to ensure effective heating of soil, and soil moisture content above 30% was recommended. Higher voltage intensity and/or ion concentration meant stronger input power, resulting in the rapider heating process and the shorter the boiling time. At a low desorption temperature (about 100°C), the Phe desorption mainly depended on the volatilization of surface Phe and the co-boiling of Phe-water. In ERH, the participation of AC would accelerate the diffusion of pollutants from the internal pores of soil particles and their redistribution with water phase, thus improving the Phe removed by co-boiling. It was noteworthy that AC just greatly promoted solid-liquid mass transfer, but it hardly promoted desorption directly, and the removal still depended on Phe-water co-boiling. The Phe desorption efficiency could be significantly improved from 14.0~18.4% to 59.6~70.8% under the combined action of current strengthening Phe diffusion and co-boiling. Thermogravimetric and product analysis confirmed that no new organic matter was generated, but only Phe entered the gas phase through phase change.
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PubMed
高影响因子
MICROCHIMICA ACTA
·
2024
·Vol. 191
·期 2
·1-10
·
IF 5.3
Wu Wei,Shi Yuhan,Liu Jingya,Liu Xiaoyu,Liu Hao,Wang Tao,Zhang Guoqi,Xu Zhihong
Household storage of pharmaceuticals to extract raw materials synthesized from carbon points facilitates the utilization of solid waste resources. A novel ratiometric fluorescence sensing technique was developed to ascertain the presence of horseradish peroxidase (HRP) in fruits and vegetables. The method employed a fluorescent probe, synthesized from expired amoxicillin (referred to as carbon dots, or A-CDs), serving as a reference fluorophore. Additionally, 2,3-diaminophenazine (DAP) was utilized as a specific response signal. DAP resulted from a catalytic reaction system involving phenylenediamine and hydrogen peroxide under the catalysis of HRP. The fluorescence intensity corresponding to DAP at 562 nm exhibited a substantial increase, simultaneous with the fluorescence quenching of A-CDs at 450 nm. The ratiometric fluorescence nanosensors displayed a broad linear range and high sensitivity for the detection of HRP. Across the concentration range 0.01 to 6 U L −1 , the fluorescence intensity ratio between DAP and A-CDs demonstrated a proportional increase with rising HRP concentration, achieving an impressive detection limit of 0.002 U L −1 . The recovery of HRP in fruit and vegetable samples ranged from 96.1 to 103%, with an RSD value of less than 3.8%. The proposed method facilitated the screening of inhibitors of HRP enzyme activity, contributing to the preservation of freshness in fruits and vegetables. Graphical
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PubMed
高影响因子
JOURNAL OF RADIOANALYTICAL AND NUCLEAR CHEMISTRY
·
2024
·Vol. 333
·期 3
·1155-1171
·
IF 1.5
Wu Lang,Liang Lili,Liu Datong,Wang Haijun,Lin Xiaoyan
Radioactive aerosols produced by nuclear accidents and decommissioning of nuclear power plants would cause tremendous radioactive damage to the environment and human body. The development of a radioactive aerosol suppressant is of great significance in the treatment of radioactive aerosols. In this study, a three-dimensional biomass-based polymer pectin-g-acrylic acid-acrylamide (pectin-g-poly (AA-co-AM)) SAP with high water absorbency and high agglomeration was prepared by solution polymerization. The results showed that the water absorbency of pectin grafted with acrylic acid and acrylamide reached 1064 g/g. Furthermore, under the synergistic effect of water absorption and agglomeration of the material, the sedimentation efficiency of simulated radioactive aerosol by 30 min after using suppressant is 91.21%.
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JOURNAL OF POLYMER RESEARCH
·
2023
·Vol. 31
·期 1
·1-11
·
IF 2.8
Guo Zhenyu,Song Weiqiang,Wei Xueqin,Feng Yu,Song Yihong,Cheng Wenxi
Composites of poly(lactic acid) (PLA) and poly(butylene adipate-co-terephthalate) (PBAT) with different mass ratio, containing nano-sized calcium carbonate, benzophenone and triallyl isocyanurate, were prepared by using a double screw extruder, and blown into films by extrusion blow molding. After ultraviolet (UV) exposure at irradiation doses (ID) of 20 J/cm 2 and 40 J/cm 2 , the mechanical, dynamic mechanical and thermal properties of the radiated films were tested and compared with that of the unradiated. The tensile strength of the PLA/PBAT (100/0) film with single PLA phase increased after exposure to UV light, but its fracture energy decreased. In contrast, both the tensile strength and fracture energy of PLA/PBAT (70/30) film with PLA and PBAT co-continuous phases increased after exposure, but both the tensile strength and fracture energy of PLA/PBAT (50/50) film with PBAT continuous phase decreased. The glass transition temperature ( T g ) of PLA/PBAT (100/0) film increased after exposure to UV light, but the T g of both PLA/PBAT (70/30) and (50/50) films unchanged or varied within the error range. The crystallization temperature ( T c ) of all the films did not changed after UV exposure, but the crystallizability significantly decreased. It suggested that UV irradiation was a simple and effective technique to simultaneously improve the strength and toughness of the film with PLA and PBAT co-continuous phases.
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JOURNAL OF POLYMER RESEARCH
·
2024
·Vol. 31
·期 2
·1-12
·
IF 2.6
Lei Jinxuan,Meng Lingxin,Zhao Pengyun,Wang Jiayin,Lan Tian,Xu Jingmei
A series of poly(aryl ether ketone sulfone) polymers (C-PAEKS-DBS) were synthesized from 4-carboxyphenyl hydroquinone, allyl bisphenol S, and 4,4-difluorobenzophenone by nucleophilic polycondensation. And further a series of side chain sulfonated poly(aryl ether ketone sulfone) proton exchange membranes (CPDA-x) were prepared by simply introducing hydrophilic long alkyl side chains (AMPS) into the polymers by means of double bond cross-linking. The structure of the prepared CPDA-x were characterized by FT-IR, 1 H NMR and SEM. This series of composite membranes showed excellent dimensional stability which including moderate water absorption (ranging from 27.91% to 33.33% at 80 °C) and low swelling ratio (ranging from 10.26% to 16.67% at 80 °C). In addition, the prepared films also exhibited high oxidative stability and mechanical property. This simple strategy for the producing of proton exchange membranes (PEMs) has certain potential and may be applied to the producing of fuel cell membranes with hydrophilic and hydrophobic phase separation structures.
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高影响因子
BIOLOGICAL TRACE ELEMENT RESEARCH
·
2023
·Vol. 202
·期 7
·3180-3192
·
IF 3.9
Nong Weihua,Wei Gaomeng,Wang Junli,Lei Xiaocan,Wang Jinyuan,Wei Yanhong,Dong Mingyou,He Liqiao
This study aimed to investigate the protective effect of nicotinamide mononucleotide (NMN) on testicular spermatogenesis in aluminum chloride (AlCl 3 )-exposed rats and to elucidate the potential underlying mechanism. The results indicated that AlCl 3 -induced testicular damage, leading to reduced sperm quality, increased apoptosis, decreased cell proliferation, and impaired Sertoli cell function in rats. Additionally, glycolytic metabolism was observed to be hindered. However, after NMN treatment, there was a noticeable improvement in testicular damage among the rats, marked by increased sperm quality, reduced apoptosis, enhanced cell proliferation, improved Sertoli cell function, and an activated glycolytic metabolism. The findings of this study suggest that NMN alleviates testicular spermatogenesis impairment induced by AlCl 3 exposure through the inhibition of spermatogenic cell apoptosis, promotion of spermatogenic cell proliferation, and activation of glycolytic pathways. The study contributes an experimental foundation for potential future clinical applications of NMN in cases of AlCl 3 -exposed spermatogenic dysfunction.
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高影响因子
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