COLLOID AND POLYMER SCIENCE
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2026
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IF 2.9
Wei Zeyu,Li Xinxin,Xu Zixiang,Fan Zhen,Li Yuzeng,Feng Zhenyu,Li Qinran,Zhang Hongfeng,Deng Qiliang
N-terminal epitope-imprinted temperature-sensitive polymer on silica particle was prepared using a reversible addition-fragmentation chain transfer (RAFT) strategy, with the N-terminal nonapeptide of cytochrome c as template. 2-Dodecylsulfanylcarbothioylsulfanyl-2-methylpropionic acid (DMP) was used as a chain transfer agent to regulate the polymerization of the imprinted layer, thereby enhancing the recognition performance for the peptide and target protein. After the epitope modification, a surface-imprinted polymer with a controlled imprinted layer was synthesized using monomers and crosslinkers via the RAFT radical polymerization method. As the classic temperature-sensitive functional monomer, the addition of N-isopropylacrylamide imparts temperature-responsive properties to the prepared imprinted polymer. After optimizing the ratio of functional monomers and the recognition temperature, the imprinted particles achieve optimal adsorption capacity and imprinting factor (IF) at a recognition temperature of 45 °C. The highest adsorption capacity for GI-9 is 1.50 mg/g, with an IF of 2.33, while the maximum adsorption capacity for Cyt c reaches 8.39 mg/g, with an IF of 2.16, which were clearly higher than the IF of the material without the RAFT strategy. Furthermore, the temperature-sensitive imprinted polymers exhibit acceptable binding capacity and IF for Cyt c, enabling selective recognition within multi-protein mixtures. The protein recognition performance remained at approximately 89.3% after five adsorption-desorption cycles, with almost no decrease of IF. All these results indicate that the imprinted particles exhibit acceptable selectivity, good reusability, and sensitivity to recognition temperature conditions. It is expected to be further applied in the selective recognition and controlled release of target proteins.
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CELLULOSE
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2026
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IF 4.6
Xin Yasen,Wang Miaomiao,Zou Ziwei,Wang Zongde,Song Fei,Huang Chen,Wu Ting,Zou Xiuxiu
Cellulose fiber (CF) is widely used as a flexible substrate in material science and bio-medical engineering. However, a majority of traditional research focuses solely on overcoming the bottleneck of CF in mechanical properties and improving resistance characteristics attributed to self-defects, ignoring the selection of non-toxic reinforcing agent and green, efficient and scalable production demands. In this work, a clean and scalable strategy, sizing process of waterborne emulsion was proposed for reinforcing CF paper. This innovative approach focused on controlling the insertion of 2D tung oil anhydride (TOA) layer based on the thermoset of TOA in the thermal reaction to form ester bond between cellulose and TOA due to the high chemical activity of TOA. Accordingly, the extensive ester bonds between CF and TOA enhanced cross-linking density and interfacial adhesion between CF, resulting in excellent tensile strength and toughness. Particularly, TOA/CF paper showed a tensile strength of 87.62 MPa, Young's modulus of 2.98 GPa and impact strength of 31.26 kg . f/mm 2 when the added content of TOA was 7 wt%. Moreover, the TOA/CF paper exhibited better hydrophobicity (water contact angle of 117° ± 3°) and thermal stability than pure CF paper. The developed TOA/CF paper featuring green and high yield fabrication has promising applications as a flexible substrate in various industries.
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JOURNAL OF MATERIALS SCIENCE
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2026
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IF 4.4
Diao Qun,Chang Lu,Zeng Yong,Chen Jimin
The additive manufacturing of complex Zn 2 SiO 4 –TiO 2 (ZST) microwave dielectric ceramics via vat photopolymerization (VPP) presents challenges in balancing densification with phase purity. This study systematically investigates how the initial SiO 2 precursor particle size (30 nm, 300 nm, and 5 μm) governs the entire process–property relationship. While the use of nano-sized SiO 2 particles promoted sintering activity and improved densification, it also led to the emergence of a secondary phase with high dielectric loss, which adversely affected the quality factor ( Q × f ). Conversely, larger (micron-sized) particles suppress this impurity, ensuring high phase purity at the cost of slightly lower density. By leveraging this understanding, the ZST ceramic derived from 5 μm SiO 2 (ZST3) achieved a favorable balance of properties, exhibiting a high quality factor ( Q × f ), a suitable dielectric constant ( ε r ), and excellent thermal stability with a near-zero τ f value. This study demonstrates that controlling the precursor particle size is an effective method for tailoring the microstructure and phase composition, thereby enhancing the performance of additively manufactured microwave dielectrics.
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IONICS
·
2026
·
IF 3.4
Xiang Yao
The development of efficient Metal-Nitrogen-Carbon (M-N-C) electrocatalysts is typically hindered by complex synthesis procedures and high-temperature treatments that often lead to active site aggregation. Herein, we report a facile, room-temperature plasma-driven strategy to engineer a high-performance Co 3 O 4 @GR-N composite, effectively circumventing these limitations. Unlike conventional thermal methods, this strategy utilizes a synergistic N 2 /H 2 plasma atmosphere to simultaneously achieve high-level N-doping of the graphene support and targeted enrichment of oxygen vacancies (O Vs ) in Co 3 O 4 . This dual-optimization creates a robust Co-N-C interface that electronically modulates the active sites while maximizing their exposure. Consequently, the optimized catalyst exhibits significantly enhanced Oxygen Evolution Reaction (OER) performance in alkaline media, delivering a current density of 10 mA cm − 2 at a low overpotential of 325 mV, significantly outperforming its thermally annealed counterparts. This work establishes the plasma strategy as a powerful, generalizable pathway for the precise defect engineering of advanced electrocatalysts without compromising structural integrity.
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MACROMOLECULAR RESEARCH
·
2026
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IF 3.7
Jia Yuan,Yang Ziyi,Yang Juxiang,Li Beibei,Liu Zhen
Hyperbranched polysiloxanes (HBPSi) are novel non-conjugated polymers with aggregation-induced emission (AIE) and modifiable terminals, and have attracted attention due to their unique topology and functional potential. In this study, two AIE-active HBPSi derivatives (OA-HBPSi and IBO-HBPSi, where OA stands for oleic acid and IBO stands for isobutyric acid) containing C=C and acyloxy groups were successfully synthesized via transesterification. Gel Permeation Chromatography (GPC) was used to characterize their molecular weight distributions; Fourier Transform Infrared Spectroscopy (FTIR) and solid-state Photoluminescence (PL) were employed to elucidate their structure-property relationships. Ultraviolet-Visible (UV-Vis) spectroscopy and fluorescence spectrophotometry were applied to investigate their AIE behavior under solvent concentration gradients, with a focus on luminescence mechanisms. The results showed a non-monotonic relationship between fluorescence intensity and the molecular weight (M w ) of HBPSi derivatives: fluorescence intensity is enhanced with moderate M w elevation but reduced at excessively high M w due to molecular packing effects and acyloxy group rotation. Notably, as the volume fraction of CCl 4 reached the range that induces significant polymer aggregation, the intensities of both excitation peaks (266–294 nm, UV region) and emission peaks (440–460 nm, blue visible region) increased exponentially—this trend reflects the dependence of blue luminescence on polymer aggregation degree, supporting the proposed cluster-induced emission hypothesis. Consistent with FTIR spectral shifts and solvent-dependent PL behavior, we propose a mechanism hypothesis: the AIE of these derivatives originates from the synergy of “non-conjugated functional group clusters” in the polymers. Cluster-induced electronic delocalization and intramolecular charge transfer (ICT) between C=C and acyloxy groups may facilitate exciton radiative transitions, while the 3D hyperbranched spatial hindrance restricts excessive intermolecular aggregation—collectively suppressing non-radiative transition pathways. Graphical abstract
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CATALYSIS SURVEYS FROM ASIA
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2026
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IF 2.5
Khan Khyrullah,Wang Wei,Tian Hongkai,Chang Zhidong,Dong Bin,Ghebretatios Natnael,Rasheed Kiran,Otota Benard
The aggregation of TiO 2 precursors affects the structural evolution and catalytic performance of sulfated titania, highlighting a relationship between microscale and macroscale reactivity. In the present work, the sulfated titania (TiO 2 /SO 4 2− ) solid acid catalysts were synthesized through the impregnation approach using two different precursors, pre-aggregated TiO 2 (microscale) and molecular-scale Ti(OH) 4 . The catalysts were characterized using X-ray diffraction, Fourier transform infrared spectroscopy, Brunauer-Emmett-Teller analysis, and ammonia temperature-programmed desorption (NH 3 -TPD). Their catalytic activity was tested in the transesterification reaction of ethyl acetate with n-butanol. The TiO 2 /SO 4 2− derived from Ti(OH) 4 precursor exhibited a single-phase anatase structure with (92%) higher specific surface area (63.85 m 2 g − 1 vs. 33.38 m 2 g − 1 ), smaller crystallite size (8.05 nm), and higher catalytic conversion (70%) as compared to the catalyst prepared from pre-aggregated TiO 2 . These differences are attributed to variations in precursor aggregation, which influence crystallite growth, sulfate dispersion, and surface area acidity, thereby enhancing catalytic performance during transesterification. The present work establishes a link between TiO 2 precursor aggregation and the catalytic activity of TiO 2 /SO 4 2− . The results demonstrate that the aggregation state of the TiO 2 precursor inherently governs the physicochemical characteristics and catalytic behavior of sulfated titania, providing a rational basis for tailoring solid acid catalysts for esterification and transesterification reactions.
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JOURNAL OF NANOBIOTECHNOLOGY
·
2026
·Vol. 24
·期 1
·238
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IF 15
Zhang Yufeng,Qi Guilin,Zhang Liang,Chen Yinuo,Fu Jiahui,Yang Li,Ke Zhiqiang,Ma Yanyan,Zhao Wenyuan,Zhao Yanfang,Ye Luyang,Jiang Minghao,Cai Leyi,Zhang Yihui,Liu Xueying,Li Xiaokun,Wu Ping,Wu Minhao,Wang Zhouguang
Diabetes-induced osteoporosis significantly elevates the risk of fracture-related disability and mortality. Developing effective therapeutic strategies for diabetic-related bone defects has become a pressing concern in both clinical and research domains. This study innovatively constructs a near-infrared light-responsive (NIR) intelligent hydrogel system (carboxymethyl chitosan/gelatin/black phosphorus@bFGF, CG/BPb), utilizing carboxymethyl chitosan and gelatin as the matrix while integrating polydopamine (PDA)-functionalized black phosphorus nanosheets (BP@PDA) as a controlled-release carrier for basic fibroblast growth factor (bFGF). The CG/BPb hydrogel demonstrated remarkable mechanical strength (up to 25 kPa compressive stress at 55% strain) and antioxidant capacity, scavenging 81.1% of ROS and 83.3% of hydroxyl radicals. Under NIR irradiation (1 W/cm², 5 min), the hydrogel achieved a stable photothermal temperature of 42 ± 1 °C, enabling controlled release of bFGF (60% cumulative release within 20 min at pH 6.5) and phosphate ions. In vitro, assessments revealed that the hydrogel enhanced osteoblast viability by 85% in scratch assays and upregulated osteogenic genes (ALP, Runx2, and OCN). Additionally, it also promoted M2 macrophage polarization (increased CD206, decreased iNOS) and suppressed osteoclast activity via NFATc1 and MAPK pathways. In vivo, in a diabetic rat calvarial defect model, the CG/BPb + NIR group showed significant bone regeneration, with increases in bone volume fraction (BV/TV) and bone mineral density (BMD), alongside enhanced vascularization (elevated CD31/CD34/α-SMA expression). This innovative strategy, grounded in material design and synergistic biological functions, not only provides a new solution for the treatment of diabetic bone defects but also promotes technological progress in the field of bone tissue engineering, with substantial academic value and practical applications. Graphical
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JOURNAL OF MATERIALS SCIENCE
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2026
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IF 4.4
Song Tongyang,Zhang Jianxu,Eyoka Bouma Annas Benit,Ye Linjing
Driven by renewable solar energy, biomass reforming under mild conditions for synergistic hydrogen production has emerged as a rapidly developing and promising approach, enabling not only high-purity hydrogen generation but also offering new avenues for biomass reutilization. In this work, a spherical ZCS/SiO 2 composite catalyst was fabricated by anchoring ZnCdS (ZCS) nanoparticles onto SiO 2 nanospheres via a water bath technique coupled with in situ growth. The physicochemical properties of the resulting catalyst were systematically investigated through comprehensive characterization methods, and the behavior of photogenerated charges was analyzed using photoelectrochemical measurements. Among the prepared samples, the ZCS/SiO 2 -100% catalyst exhibited the highest hydrogen evolution activity, achieving a hydrogen evolution rate of 109.16 μmol g −1 h −1 when sodium lignosulfonate, derived from the bamboo pulping process, was used as the substrate. This enhanced photocatalytic hydrogen evolution performance is primarily attributed to the introduction of SiO 2 , which increases the number of active sites and expands the contact area between the catalyst and reactants. Furthermore, a plausible photocatalytic reaction mechanism is proposed. It is anticipated that this study will provide a promising strategy for green hydrogen production, high-value conversion of organic waste, and the advancement of efficient photocatalytic materials.
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JOURNAL OF NANOBIOTECHNOLOGY
·
2026
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IF 15
Yuan Yin,Panyang Gu,Hanyu Jiang,Yumei Yang,Shujun Wang,Fei Yuan,Wenrui Zhong,Miao Chen,Meichun Deng
The widespread use of plastic products has led to a serious environmental problem, with nanoplastics ubiquitously contaminating the environment and sustaining human exposure, yet the impacts of nanoplastics on human health remain poorly understood. In this study, based on preliminary epidemiological investigations, we found that abnormal pain perception exists in populations chronically exposed to manufacturing environments that mainly produce polystyrene plastics. Further mechanistic studies demonstrated that high-dose polystyrene nanoparticles (PS NPs) induce pain hypersensitivity and elucidated their molecular underpinnings. Upon high-dose PS NPs exposure, microglia in the spinal dorsal horn internalized a fraction of the PS NPs, which were subsequently found to bind to mitogen-activated-protein-kinases (MAPK) pathway components (ERK, JNK, and p38). Molecular dynamics simulations further suggested that this binding could induce conformational alterations in the MAPK components, potentially enhancing the flexibility of their phosphorylation sites (Thr-X-Tyr) and thereby facilitating activation by upstream kinases. As a canonical inflammatory and pain-associated pathway, MAPK activation elevates neuroinflammatory cascades in the spinal dorsal horn, driving neuronal hyperexcitability and, consequently, pain hypersensitivity. Notably, the PS NPs-induced hypersensitivity was reversed by microglial depletion (PLX5622) and inhibition of the MAPK pathway. Collectively, our findings delineate PS NPs-triggered sensory pathophysiology and establish a proof-of-concept mechanistic nexus between environmental pollutants and aberrant somatosensation.
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DIGESTIVE DISEASES AND SCIENCES
·
2026
·
IF 2.8
Ji Yuxiao,Li Pengchong,Liu Yuqi,Shen Dan,Hao Yuanzhen,Liu Yisi,Song Huixin,Sun Wei,Zhu Shengtao,Li Peng,Zhang Shutian
Introduction Ulcerative colitis (UC) is an inflammatory disease characterized by colonic epithelial damage. With prolonged disease duration, the risk of malignant transformation increases significantly. However, the mechanisms driving the progression from chronic inflammation to tumorigenesis remain incompletely understood. This study aimed to identify a set of genes that may contribute to the transition from healthy controls (HC) to UC and ultimately to colitis-associated colorectal cancer (CAC). Methods We conducted bioinformatic analysis of four Gene Expression Omnibus (GEO) datasets to identify genes involved in the transitions from HC to UC and from UC to CAC. Functional enrichment and immune infiltration analyses were performed. Immunohistochemistry (IHC) validated the expression of key genes in UC patients. In vitro experiments assessed the effect of IFN- γ and TNF- α stimulation on PDL1 expression in neutrophils. Results Seven key genes—S100A8, IL33, MGP, MMP3, CFI, CLU, and CLEC4E—were upregulated during HC to UC and UC to CAC transitions. These genes were linked to neutrophils and pathways like Interferon (IFN)- γ , Tumor Necrosis Factor (TNF)- α and oxidative phosphorylation. Immunohistochemistry in mice confirmed expression levels, with five genes showing statistical significance. Additionally, IFN- γ and TNF- α stimulation significantly increased Programmed Death-Ligand 1 (PD-L1) expression in neutrophils. Conclusion We identified seven genes that are persistently upregulated during the progression from HC to UC and CAC. These genes influence neutrophils and inflammatory/tumorigenic pathways. The upregulation of PD-L1 in neutrophils suggests that neutrophil-mediated immune suppression may contribute to CAC progression, supporting their potential as molecular markers and therapeutic targets for early intervention in UC-related cancer.
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高影响因子
Biochar
·
2026
·Vol. 8
·期 1
·48
·
IF 15.1
Zhang Xiangyu,Zhang Peng,Jiao Le,Zhang Yanwei,Sun Hongwen,Liu Chenglan
Agricultural herbicide contamination in soil poses a significant challenge to global food security and ecosystem health. However, conventional remediation strategies often neglect the co-control of parent compounds and their more mobile transformation products, thereby increasing the risks of crop uptake and incomplete detoxification. Here, we have developed a novel nitrogen-doped biochar-modified zero-valent iron nanocomposite (NC-ZVI) that enables multi-interface regulation of pollutants in soil–plant systems, simultaneously promoting soil remediation and safeguarding crop health. Engineering of atomic Fe–C and Fe–N coordination along with N-doped active sites modulated the electronic structure of ZVI, enhancing the surface reactivity and electron capability in NC-ZVI. This enabled rapid removal of approximately 90% of acetochlor in soil within 7 d by reinforced interfacial catalytic degradation. NC-ZVI also promoted the release of iron ions, driving the formation of iron plaques on maize root surfaces. These plaques established a dynamic protective barrier that reduced the total concentrations of acetochlor and its degradation products in maize by 81.2% while maintaining iron nutrient uptake. The multi-interface interaction strategy not only restored maize productivity, increasing its aboveground biomass by 208.4%, but also preserved soil microbial diversity, all at a cost-competitive level. Overall, this work advances the understanding of the interactions between biochar-based materials and pollutants in soil–plant systems, providing a powerful tool to tackle soil pollution and enhance food safety.
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JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE
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2026
·
IF 4.7
Hailong Feng,Hongtao Luo,Xiugeng Li,Yang Jiang,Baihui He
Ferroptosis is a novel anticancer therapeutic approach that effectively circumvents the apoptotic cell death mechanism. Nonetheless, enhancing the catalytic effectiveness of the Fe 2+ -mediated Fenton reaction and effectively inducing ferroptosis present significant challenges. In this study, motivated by the kinetics of hyperthermia-improved Fenton reactions, we initially developed Quercetin (QT)-Curcumin (CUR)-Iron (Fe)-coordinated nanochelates for photothermal-improved ferroptosis in anticancer therapy. We precisely adjusted the appropriate feeding rate of polyvinylpyrrolidone (PVP), QT, CUR, and Fe to develop unique nanofibrous QT-CUR-Fe chelates, referred to as QCFs. The differences in size and structure made QCFs more practical for colorectal cancer therapy than ultrasmall QT-Fe (QFs). Under NIR laser exposure, QCFs can continuously enhance the formation of depleted excessive GSH and toxic hydroxyl radicals (•OH), leading to increased lipid peroxidation (LPO) accumulation and subsequently activating the ferroptosis pathway in vitro. Furthermore, the incorporation of CUR may suppress prostaglandin E2 (PGE2) and cyclooxygenase-2 (COX-2) in conjunction with PTT-improved ferroptosis colorectal therapy to facilitate dendritic cell (DC) maturation, elicit immunogenic cell death (ICD), and enhance synergistic antitumor immunotherapy. Overall, this study proposed a way to integrate small-molecule immunomodulators into QFs nanocoordination to overcome its limitations, thereby fostering a novel design concept for colorectal cancer therapy.
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