Journal of Physical Chemistry Letters
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2025
·
IF 4.6
Weidong Liang,Yong Zhang,Dongniu Wang,Jianzhao Peng,Jinshuo Zou,Huiqi Li,Zhongxin Song,Manlin Tan,Jun Yu,Lei Zhang
Optimizing the electronic structures of metal sites is desirable for high intrinsic activity. Incorporated metal atoms in a carbon substrate can establish strong electronic interaction with loaded metal oxides. However, this structure may be unstable in a harsh oxygen evolution reaction (OER) environment. Herein, we take the NiSAFe sample of Ni–N–C supported Fe2O3 nanoparticles (NPs) as an example. Both in situ and ex situ characterizations show that the OER activation process facilitates the transformation of Ni single atoms into atomically dispersed NiOOH active species while retaining Fe2O3 NPs. Accordingly, abundant structural defects are formed in the carbon support, enhancing electron transfer and upshifting the d-band center of the NiFe catalyst. As a result, the catalyst exhibits accelerated OER kinetics and optimized adsorption energies for reaction intermediates, delivering outstanding intrinsic activity. A low overpotential of 230 mV at 10 mA cm–2 and a turnover frequency (TOF) more than 9 times higher than that of commercial RuO2 are achieved.
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EUROPEAN POLYMER JOURNAL
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2025
·
IF 6.3
Naike Wang,Tian Xia,Shuo Wu,Peng Zhu,Mengmeng Guo,Bo Liang
The development of polymeric materials combining high mechanical strength with environmentally adaptive self-healing capability represents a key objective in smart materials research, particularly for wearable biomedical applications. This study synthesized a polyurethane-based material (PUAM) incorporating poly(N-isopropylacrylamide) (PNIPAM), and varying contents of custom-synthesized ureido-pyrimidinone (UPy) units with quadruple hydrogen bonds to investigate humidity-responsive self-healing behavior. Fourier transform infrared (FTIR) spectroscopy demonstrated a progressive increase in hydrogen bonding index (HBI) with higher UPy content. Dynamic mechanical analysis (DMA) further revealed monotonic enhancements in both storage modulus and dynamic crosslinking density ( V d ). Optical microscopy observations of scratch closure under different humidity conditions and NaCl vapor environments confirmed effective humidity-responsive self-healing, with performance positively correlating with UPy concentration. Water contact angle and hygroscopicity measurements show that a high UPy content improves the moisture absorption performance of the material. The absorbed water molecules function as plasticizers to enhance polymer chain mobility and facilitate hydrogen bond reorganization, thereby improving self-healing performance. This work provides a feasible strategy for designing high-performance smart materials with tunable humidity-responsive healing properties.
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JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
·
2025
·Vol. 29
·期 7
·e70539
·
IF 4.2
Tianyi Ji,Xiangying Li,Jiachen Li,Guan Wang
Wnt signalling is a highly conserved signalling pathway that plays an important role in a variety of biological processes. Frizzled (Fzd) family proteins are receptors for Wnt ligands. The physiological processes involved in mature trafficking of Fzd proteins remain elusive. Here, we identified asparagine residues 59 and 144 as the N-glycosylation modification sites of Fzd4. Sequence analysis of Fzd4 in different species showed that the two asparagine residues were highly conserved. N-glycosylation modification of Fzd4 is indispensable for its maturation and transport to the plasma membrane. N-glycosylation modification enhances the stability of Fzd4 and is also necessary for Fzd4 activity, which promotes Fzd4 interaction with Wnt ligands and co-receptor Norrin. Knockout of Fzd4 in the non-small cell lung cancer (NSCLC) cell line A549 followed by replenishment of Fzd4 glycosylation site mutants inhibited the growth and migration ability of A549 cells in vitro and in vivo. In summary, we identified N-glycosylation modification sites of Fzd4. N-glycosylation modification of Fzd4 is necessary for its stability and activity. When N-glycosylation modification is absent, Fzd4 cannot mediate the Wnt/β-catenin signalling pathway, which can inhibit the proliferation and migration of NSCLC and provide new targets and strategies for the treatment of NSCLC.
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Sustainability
·
2025
·Vol. 17
·期 10
·4358
·
IF 3.3
Yuantao Han,Yuchuan Ye,Wanjin Yu,Shaohong Zang,Lili Ji,Shijie Li,Liuye Mo
The synthesis of high performance catalysts for the catalytic wet oxidation (CWO) of N-methyldiethanolamine (MDEA) in water remains a challenge, and is a topic of considerable importance in relation to sustainability. In this paper, a Ru-CNx/CeO2catalyst was synthesized through a modified impregnation process for the CWO of MDEA, exhibiting a high activity of 80% COD removal at 180 °C and 2.5 MPa. EPR, Raman, and XPS characterizations revealed that the CNxspecies facilitated the reduction in Ru4+to Ru0species and enhanced the Ru–Ce interaction to form a high-density Ru-O-Ce structure with Ce3+sites, which strongly correlate to the generation of oxygen vacancies. The oxygen vacancies enabled the adsorption and activation of the oxygen, generating active species (h+, ·O2−, and ·OH) that effectively oxidized the MDEA during the catalytic reaction.
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ChemPlusChem
·
2025
·
IF 2.8
Wen Feng,Congyue Sun,Xiaojin Li,Xiliang Luo,Liu Wenqi
The exploitation of an efficient and stable oxygen reduction reaction (ORR) catalyst plays a crucial role in the slow kinetics of the cathode in proton exchange membrane fuel cells (PEMFC). In this study, a catalyst loaded with PtCo alloys on Co and N co-doped carbon nanotubes (PtCoNC) was synthesized for oxygen reduction reaction, which has high activity and stability. The carbon nanotube structure provides efficient transport channels for reactant exchange and product transport, as well as provides a wealth of triple-phase sites, that improves the utilization of Pt. Further, the PtCoNC catalyst exhibits robust metal-support interactions, which can be attributed to the anchoring of the Co-Nx sites to Pt. Theoretical calculations indicating an increase in binding energy and a reduction in layer spacing provide conclusive verification of the presence of augmented interactions between PtCo nanoparticles and the support. As a result, the low Pt-loaded (0.025 mg cm-2) PtCoNC catalyst demonstrates superior ORR activity to that of commercial Pt/C with an impressive half-wave potential of 0.893 V in 0.1 M HClO4 solution. At 0.9 V, its mass activity and specific activity are 3 and 2.6 times that of commercial Pt/C, respectively. It also shows better stability in acidic environment.
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MACROMOLECULAR BIOSCIENCE
·
2025
·
IF 4.1
Shijie Wang,Shanshan Xiao,Ning Li,Yue Xu,Ziyuan Song
Poly(ethylene glycol) (PEG)-polypeptide drug nanocarriers have garnered increasing attention during last decades. However, the tedious polymer synthesis and the stability issue greatly limit their further development. Herein the biphasic polymerization platform is reported for the easy access of a series of crosslinked PEG-polypeptide nanoparticles for enhanced drug loading and selective drug release. The accelerated polymerization allows for the preparation of a library of PEG-polypeptides from crude monomers with different polypeptide segments for structural optimization. Nanocarriers with redox-responsive de-crosslinking and enhanced drug loading are therefore obtained based on the model drug, doxorubicin, which exhibits selective killing of cancer cells. This study provides a synthetic method for efficient preparation of PEG-polypeptide nanocarriers, benefiting the downstream drug loading and therapeutic studies.
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ANALYTICA CHIMICA ACTA
·
2014
·
IF 4.517
Qing Wang,Jie Chen,Kun Huang,Xin Zhang,Li Xu,Zhi-guo Shi
A hydrophilic stationary phase (SP) was prepared through grafting N -methylene phosphonic acid chitosan on magnesia–zirconia particles (P-CTS-MgO–ZrO 2 ) via Lewis acid–base interaction. The resulting material was characterized by thermogravimetric analysis, Fourier transform infrared spectroscopy, scanning electron microscope and nitrogen adsorption analysis. The chromatographic performance of P-CTS-MgO–ZrO 2 was systemically evaluated by studying effect of acetonitrile content, pH and buffer concentration in the mobile phase. The results demonstrated that the novel SP provided hydrophilic, electrostatic-repulsion and ion-exchange interactions. Compared to the bare MgO–ZrO 2 , P-CTS-MgO–ZrO 2 exhibited superior peak shape, reasonable resolution and reduced analysis time in separation of basic analytes. Besides, remarkable resolving power of acids, i.e. six non-steroidal anti-inflammatory drugs which failed to be eluted from the bare MgO–ZrO 2 , was obtained with the theoretical plate number (N/m) of 4653–31313, asymmetry factor <1.21 and the resolution of 1.6–3.4. Finally, P-CTS-MgO–ZrO 2 SP was applied to separate monosaccharides, phospholipids and peptides. P-CTS-MgO–ZrO 2 was a promising hydrophilic SP for wide applications.
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Food Chemistry-X
·
2025
·
IF 8.2
Yingyi Lin,Yong Wang,Ying Li
Camellia oleifera Abel. is an important woody oilseed tree to help increase the self-sufficiency rate. In this study, lipid extraction focuses more on the solvent extraction of Camellia seed oil (CO) cakes rather than conventional cold pressing, where the performance of candidate alternative green solvents selected from hurdle technology was first evaluated. Compared to n-hexane (89.50 ± 0.00 %) and subcritical n-butane (83.75 ± 0.43 %), 2-methyloxolane (2-MeOx) performed the best with the comprehensive consideration of extraction ratio (94.79 ± 0.00 %), lipid composition and environmental impact (0.38 ± 0.07 kg of CO 2 emission). Intriguingly, 2-MeOx exhibited the highest diffusion rate at both 25 °C and 55 °C in the extraction kinetic study, which could also extract the highest total phenolic contents (351.6 ± 0.02 mg GAE/kg dw) corresponding to its best oxidative stability. Besides, Hansen solubility modeling could help better understand the dissolving mechanism. 2-MeOx was demonstrated as the optimal alternative bio-based solvent to n-hexane with comparable extractability and selectivity in the CO extraction.
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Catalysts
·
2022
·Vol. 12
·期 11
·1449
·
IF 4.501
Haiqin Lu,Guilu Xu,Lu Gan
In the present study, nitrogen doped biochar (N-PPB) and nitrogen doped activated biochar (AN-PPB) were prepared and used for removing bisphenol A (BPA) in water through activating peroxymonosulfate. It was found from the results that N-PPB exhibited superior catalytic performance over pristine biochar since nitrogen could brought about abundant active sites to the biochar structure. The non-radical singlet oxygen (1O2) was determined to be the dominant active species responsible for BPA degradation. Having non-radical pathway in the N-PPB/PMS system, the BPA degradation was barely influenced by many external environmental factors including solution pH value, temperature, foreign organic, and inorganic matters. Furthermore, AN-PPB had richer porosity than N-PPB, which showed even faster BPA removal efficiency than N-PPB through an adsorptive/catalytic synergy. The finding of this study introduces a novel way of designing hieratical structured biochar catalysts for effective organic pollutant removal in water.
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NEW JOURNAL OF CHEMISTRY
·
2021
·Vol. 46
·期 4
·1791-1799
·
IF 3.591
Jing-Jiang Liu,Fu-Hu Guo,Fu-Jun Cui,Ji-Hua Zhu,Xiao-Yu Liu,Arif Ullah,Xi-Cun Wang,Zheng-Jun Quan
N-doped porous carbon (NC) was synthesized from sugar cane bagasse, which is a sustainable and widely available biomass waste. The preferred NC sample had a well-developed porous structure, a graphene-like surface morphology and different N species. More importantly, the heterogeneous carbocatalyst exhibited superior catalytic performance in the aerobic dehydrogenation of various heterocyclic nitrogen compounds (49 examples, up to 96% yield), similar to that of C3N4 and GO. Characterization by TEM, BET and XPS accompanied by the EPR analysis revealed that the enhanced catalytic properties of NC came from its high activation ability for both O2 and heterocyclic nitrogen, attributed to the porous structure and pyridinic N (N-6) species, respectively.
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COMPOSITES SCIENCE AND TECHNOLOGY
·
2018
·
IF 5.16
Hui Ma,Huanxia Zhang,Jianda Cao,Mingqiong Tong,Jianwei Zhao,Yifei Li,Hong Xu,Wen Wu
In this work, temperature-responsive poly(N-isopropylacrylamide) (PNIPAm) was covalently grafted onto the edge of graphene oxide (GO) sheets through a facial method cross-linked by 1-(3-dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride (EDC·HCl) and N-hydroxysuccinimide in aqueous solution at room temperature. Then, the dispersion was wet spun to form a GO composite fiber . Scanning electron microscopy images suggest that severe edge distortions occur in PNIPAm-g-rGO hybrid fibers, indicating the covalent attaching of PNIPAm molecules onto the edge of graphene sheets . The PNIPAm-g-rGO fibers showed more favorable and improved electrical property than the pristine rGO fibers. Moreover, the coil-to-globule transition of the end-grafted PNIPAm chains was partially restricted by graphene sheets in the composite fiber, thereby causing the elevation of the phase transition temperature. Switching test of temperature-responsive versus electrical conductivity function has proved that the observed temperature-induced electrical conversion of the fibers was highly reversible and reproducible. Simultaneously, the composite fiber exhibited higher piezoresistive sensitivity compared with neat fiber. This smart fiber has shown remarkable potential for intelligent strain sensors, textiles, actuators, wires and on/off switches.
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ACS Applied Materials & Interfaces
·
2023
·
IF 9.5
Tian Yu,Suiting Ning,Qian Liu,Tingting Zhang,Xiangbin Chen,Ning Qi,Xianli Su,Xinfeng Tang,Zhiquan Chen
As a liquid-like material, CuAgSe has high carrier mobility and ultralow lattice thermal conductivity. It undergoes an n–p conduction-type transition during β- to α-phase transition with increasing temperature. Moreover, optimization of the thermoelectric performance of CuAgSe is rather difficult, owing to the two-carrier conduction in this material. In this work, we reported the free tuning of the conduction type and thermoelectric performance of CuAgSe by manipulating the cation vacancies. Positron annihilation measurements reveal that the increase in CuAg content can effectively suppress the cation vacancies and reduce the hole carrier concentration, resulting in n-type conduction at high temperatures. Doping with Zn at the Cu sublattice in the CuAg-excessive CuAgSe can further decrease the number of vacancies, leading to a significant decrease in hole carrier concentration. Furthermore, the reduction of vacancies leads to weakening of carrier scattering. As a result, carrier mobility is also enhanced, thus improving the thermoelectric performance of n-type CuAgSe. On the other hand, high-performance p-type CuAgSe can be achieved by decreasing the CuAg content to introduce more cation vacancies. Ultimately, both n-type and p-type CuAgSe with superb thermoelectric performance are obtained, with a zTmax of 0.84 in Cu1.01Ag1.02Zn0.01Se (n-type) and 1.05 in (CuAg)0.96Se (p-type) at 600 K and average zT of 0.77 and 0.94 between 470 and 630 K for n-type and p-type, respectively.
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