LANGMUIR
·
2024
·
IF 3.7
Longyu Liu,Xueqiu Liu,Xinyi Lu,Xinmiao Guo,Xi Chen,Weiping Li,Xiaobin Yu,Zhiqiang Cheng
Matrine (MT) is a kind of alkaloid extracted from Sophora and is a promising substitute for chemical nematicides and botanical pesticides. The present study utilized sodium alginate (SA), zeolite imidazole salt skeleton (ZIF), and MT as raw materials to prepare a pH-response-release nematicide through the electrostatic spray technique. Zinc metal–organic framework (ZIF-8) was initially synthesized, followed by the successful loading of MT. Subsequently, the electrostatic spray process was employed to encapsulate it in SA, resulting in the formation of MT/ZIF-8@SA microcapsules. The efficiency of encapsulation and drug loadings can reach 79.93 and 26.83%, respectively. Soybean cyst nematode (SCN) is one of the important pests that harm crops; acetic acid produced by plant roots and CO2 produced by root respiration causing a decrease in the pH of the surrounding environment, which is most attractive to the SCN when the pH is between 4.5 and 5.4. MT/ZIF-8@SA releases the loaded MT in response to acetic acid produced by roots and acidic oxides produced by root respiration. The rate of release was 37.67% higher at pH 5.25 compared with pH 8.60. The control efficiency can reach 89.08% under greenhouse conditions. The above results demonstrate that the prepared MT/ZIF-8@SA not only exhibited excellent efficacy but also demonstrated a pH-responsive release of the nematicide.
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PubMed
高影响因子
JOURNAL OF BIOMATERIALS SCIENCE-POLYMER EDITION
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2024
·
IF 3.6
Chongwen Ren,Qingqing Tu,Jinchao He
Glioma cancer is the primary cause of cancer-related fatalities globally for both men and women. Traditional chemotherapy treatments for this condition frequently result in reduced efficacy and significant adverse effects. This investigation developed a new drug delivery system for the chemotherapeutic drug temozolomide (TMZ) using pH-sensitive drug delivery zeolitic imidazolate frameworks (ZIF-8). These nanoplatforms demonstrate excellent biocompatibility and hold potential for cancer therapy. Utilizing the favorable reaction milieu offered by ZIFs, a ‘one-pot method’ was employed for the fabrication and loading of drugs, leading to a good capacity for loading. TMZ@TA@ZIF-8 NPs exhibit a notable response to an acidic milieu, resulting in an enhanced drug release pattern characterized by a controlled release outcome. The effectiveness of TMZ@TA@ZIF-8 NPs in inhibiting the migration and invasion of U251 glioma cancer cells, as well as promoting apoptosis, was confirmed through various tests, including MTT (3-(4,5)-dimethylthiahiazo(-z-y1)) assay, DAPI/PI dual staining, and cell scratch assay. The biochemical fluorescent staining assays showed that TMZ@TA@ZIF-8 NPs potentially improved ROS, reduced MMP, and triggered apoptosis in U251 cells. In U251 cells treated with NPs, the p53, Bax, Cyt-C, caspase-3, −8, and −9 expressions were significantly enhanced, while Bcl-2 expression was diminished. These outcomes show the potential of TMZ@TA@ZIF-8 NPs as a therapeutic agent with anti-glioma properties. Overall, the pH-responsive drug delivery systems we fabricated using TMZ@TA@ZIF-8 NPs show great potential for cancer treatment. This approach has the potential to make significant contributions to the improvement of cancer therapy by overcoming the problems associated with TMZ-based treatments.
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PubMed
高影响因子
MICROCHEMICAL JOURNAL
·
2024
·
IF 4.9
Suqi Liu,Linjiang Pang,Xiaowei Wu,Shihao Chen,Mingyi Yang,Jiyu Cheng,Guoquan Lu,Zhenhe Wang,Wei Chen,Yuge Guan,Xinghua Lu
Changes in the content of trans -caryophyllene could identify whether sweetpotatoes are infected with black spot disease. Therefore, in this study, a quartz crystal microbalance (QCM) sensor based on modified CAU-1@ZIF-8 was used for non-destructive detection of sweetpotato black spot. The experimental results showed that the constructed sensor performed best when both modified CAU-1 and ZIF-8 were present. The sensor showed a linear trend (R 2 = 0.996, limit of detection (LOD) = 0.55 ppm) in response to trans -caryophyllene in the concentration range of 20–340 ppm with a sensitivity of −0.489 Hz (ppm) −1 . The developed gas sensor was successfully used for the detection of trans -caryophyllene in real samples of sweetpotato. The experimental data showed a significant correlation with the results of gas chromatography-mass spectrometry (GC–MS) with a correlation coefficient of 0.970 ( p < 0.01). Therefore, it could be used for early warning of black spot disease in sweetpotato.
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高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2024
·
IF 13.3
Zehan Zeng,Mingzhen Zhong,Tong Liao,Xuan Zhou,Lin Shi,Xin Zhang,Ye Zhang,Jingyan Feng,Yiqian Chen,Shuya Sheng,Jun Chen,Lei Zheng,Weilun Pan,Jinxiang Chen
Plasma extracellular vesicles (EVs) have emerged as promising biomarkers for the early diagnosis of glioblastoma. However, rapid and efficient isolation and detection of tumor-specific EV subsets from plasma remains challenging. To address this, we developed an innovative integrated chip based on self-sacrificial metal–organic frameworks and the epidermal growth factor receptor (EGFR) aptamers called ZIF-8@EGFR aptamer (ZIF-8@Apt), which further coupled with a “nano-fuels”-driven DNAzyme amplification strategy. The core functionality of the constructed chip lies in its ability to capture EVs with the ZIF-8@Apt module. Once captured, numerous DNA “nano-fuel” structures are in situ assembled on the EVs’ surfaces. Subsequently, the ZIF-8@Apt@EV@nano-fuels composites are lysed to release Zn 2+ , the EVs’ nucleic acids, and additional nano-fuels for subsequent detection. Finally, a DNAzyme detection system is introduced, where the released nano-fuels activate the DNAzyme, leading to multiple signal amplification aided by Zn 2+ for highly sensitive detection of plasma EVs. This integrated approach effectively enriches and detects target EVs, achieving a significantly enhanced detection sensitivity of 500 particles/μL. In a clinical study involving glioblastoma patients, our chip demonstrated a remarkable ability to distinguish between cancer patients and healthy individuals, achieving an area under the curve (AUC) of 0.958. Moreover, the response signals of the chip can be conveniently read using fluorescence spectroscopy or microscope, offering a rapid, highly sensitive, and high-throughput analysis of plasma EVs for various application scenarios. Overall, this study introduces a comprehensive approach for the rapid isolation and accurate analysis of plasma EVs, holding significant promise for early diagnosis and disease monitoring.
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高影响因子
ACS Sustainable Chemistry & Engineering
·
2024
·
IF 7.1
Na Wang,Xiang Zhou,Youming Dong,Ying Zhang,Rong Liu,Haijiao Kang,Kaili Wang,Jianzhang Li
Natural mildew preventives, like citral, have great potential to protect bamboo from mildew, while their long-lasting antimildew performance is yet to be challenged owing to their oxidability and volatility. Inspired by biomimetic mineralization, in this work, citral@ZIF-67 particles were synthesized by encapsulating citral into a zeolite imidazolate framework-67 (ZIF-67) cage and introduced into a bamboo structure. Benefiting from the unique cage structure and large surface area of ZIF-67, it can encapsulate sufficient citral molecules. The encapsulation reduced the particle size of ZIF-67 due to the nucleation of citral. Furthermore, the surface area, pore size, and volume of citral@ZIF-67 particles gradually decreased with the increase in loading amounts of citral. ZIF-67 exhibited a certain antibacterial ability against E. coli and S. aureus. The encapsulation of citral can further enhance the antibacterial activity of ZIF-67. In addition, the citral@ZIF-67 showed slow-release performance that followed the Fickian diffusion mechanism. After the citral@ZIF-67 treatment, bamboo showed no mold spots on the surface with an infection grade of 0, which was retained, even though bamboo was conditioned at 50 °C and 85% relative humidity for 10 days. This proposed method can effectively improve the stability of natural mildew preventives and endow bamboo with long-term antimildew properties with low cost and minimized environmental impacts.
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高影响因子
IONICS
·
2024
·Vol. 30
·期 10
·6705-6718
·
IF 2.4
Ullah Mohib,Ganesan Subbulakshmi,Kumari Bharti,Zafar Mariam,Yusuf Kareem,Hussein Shaymaa Abed,Issa Salman Khalaf,Alsultany Forat H.,Singh Manmeet,Zhengxin Li,Ullah Sami
The detrimental effects of nitrite (NO 2 − ) on environment as well as living organisms have attracted immense interest to sensitively detect it in the drinking water system. So, for this purpose, we have developed a highly sensible and portable colorimetric NO 2 − sensor based on the CZ-2 nanocomposite (NC). The three dimensional (3D) with large hierarchical structure CZ-2 NC sensor was formed by the coupling of g-C 3 N 4 nanosheets (NSs) and ZIF-67 nanoparticles (NPs) by a simple hydrothermal process. The prepared sensor was successfully employed to detect NO 2 − , which manifests higher sensing characteristics like extensive sensitivity with large detection linear range of (1 × 10 −3 –7.20 × 10 −1 μM) having a R 2 of 0.999 and a lowest limit of detection (LOD) value of 0.16 ± 0.05 nM. Further, it also manifests excellent reversibility, better stability and durability, optimal reproducibility and superior repeatability. In addition, the sensor also depicts large selectivity towards NO 2 − and improved practicability in real water sampling. These commendable sensing properties were mainly ascribed to the large conductive structure and highest surface area of the CZ-2 NC structure. Thus, as a result, we analyzed that our fabricated colorimetric sensor was highly potent, its applications in the sensing fields can be explored for future perspective.
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高影响因子
MOLECULES
·
2024
·Vol. 29
·期 18
·4465
·
IF 4.2
Yun Xiong,Yifan Shu,Niyan Deng,Xiaogang Luo,Shengpeng Liu,Xiaoyu Wu
This study investigated the enhancement in bioethanol recovery from mixed matrix membranes (MMMs) by functionalizing zeolite framework-8 (ZIF-8) with imidazolate. This study focused on the separation of ethanol from low-concentration ethanol/water mixtures (typical post-fermentation concentrations of 5–10 wt%). Specifically, ZIF-8 was modified by the shell–ligand exchange reaction (SLER) with 5,6-dimethylbenzimidazole (DMBIM), resulting in ZIF-8-DMBIM particles with improved hydrophobicity, organophilicity, larger size, and adjustable pore size. These particles were incorporated into a PEBAX 2533 matrix to produce ZIF-8-DMBIM/PEBAX MMMs using a dilution blending method. The resulting membranes showed significant performance enhancement: 8 wt% ZIF-8-DMBIM loading achieved a total flux of 308 g/m2·h and a separation factor of 16.03, which was a 36.8% increase in flux and 176.4% increase in separation factor compared with the original PEBAX membrane. In addition, performance remained stable during a 130 h cycling test. These improvements are attributed to the enhanced compatibility and dispersion of ZIF-8-DMBIM in the PEBAX matrix. In conclusion, the evaluation of nanofiller content, feed concentration, operating temperature, and membrane stability confirmed that ZIF-8-DMBIM/PEBAX MMM is ideal for ethanol recovery in primary bioethanol concentration processes.
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PubMed
高影响因子
Catalysts
·
2024
·Vol. 14
·期 8
·490
·
IF 3.8
Xingxing Chen,Qing Wu,Somboon Chaemchuen,Francis Verpoort
The ring-opening polymerization of L-lactide is a crucial route for producing biodegradable polylactides (PLAs). Developing an efficient catalyst for this process poses significant challenges. Herein, we report the successful incorporation of nickel during the crystallization of ZIF-67, the derivation of the abundant and stable CoO source, to obtain the composite magnetic Ni@CoO@ZIF-67 using the solid-state thermal (SST) method. The characterization of the resulting materials revealed that nickel atoms are well dispersed in the composite CoO@ZIF-67, imparting additional magnetic properties. The composite Ni@CoO@ZIF-67 demonstrated superior performance as a heterogeneous catalyst for the ring-opening polymerization of L-lactide compared to reference materials such as Ni-Hmim, CoO, ZIF-67, and CoO@ZIF-67. Furthermore, the magnetic property of Ni@CoO@ZIF-67 offers practical advantages, enabling easier separation and recycling of the catalyst. Notably, the SST method facilitates the single-step synthesis of composite magnetic Ni@CoO@ZIF-67 under solvent-free conditions, representing a significant advancement in catalyst development. This approach not only simplifies the synthesis process but also inspires further developments of heterogeneous magnetic catalysts for a variety of effective and diverse reactions.
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高影响因子
APPLIED SURFACE SCIENCE
·
2025
·
IF 6.9
Caiyu Ge,Yuefan Wang,Yilin Wang,Zhifang Liu,Chao Chen,Yixi Xie,Pengcheng Zhao,Junjie Fei
As a natural flavonoid compound found in fruits, vegetables and herbs, luteolin (LU) has potent pharmacological activities and beneficial biological properties. Here, a Fe/Zn bimetallic ZIF pyrolysis-derived Fe-Fe 3 O 4 N-doped mesoporous carbon was in-situ grown on carbon nanofibers (Fe-Fe 3 O 4 -NPC@CNFs), and it was used as an ultrasensitive electrochemical sensing platform for the efficient detection of LU in natural samples. Multiple characterization results show that Fe-Fe 3 O 4 -NPC@CNFs is a dodecahedral particle uniformly grown on CNFs with good crystal structure and uniform elemental distribution. Its rough surface with good mesoporous structure and high specific surface area of 823.19 m 2 /g is beneficial for LU adsorption. The density of states (DOS) and adsorption energies of NPC and Fe-Fe 3 O 4 -NPC further demonstrate that Fe-Fe 3 O 4 -NPC has better electrochemical performance and adsorption effect on LU. Under optimized conditions (carbonization: 800℃, pH: 5.0, enrichment: −0.2 V for 400 s), the Fe-Fe 3 O 4 -NPC@CNFs/GCE sensor showed satisfactory detection performance for LU in the range of 0.001–1.5 μM with the limit of detection (LOD) of 0.47 nM. Furthermore, this sensor exhibits excellent anti-interference capability, reproducibility, and stability, and it was also possible to effectively detect LU in food samples. This work provides a new strategy for the quantitative analysis of LU in food.
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高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2025
·
IF 13.2
Huiqi Gao,Haiyun Ma,Jinjin Cui,Xusheng Ge,Jiajun Tan,Jianzhong Xu
Organic phase change materials (PCMs) suffer from liquid-phase leakage, insufficient solar-thermal conversion capability, inherent flammability, which severely hinders their utilization. Herein, we design a three-dimensional hierarchically porous aerogel composite PCMs that integrates hollow phosphorus-doped ZIF-8 microshells (P-ZIF-8) with chitosan (CS) and MXene nanosheets for multifunctional synergy. Specifically, the hierarchically porous aerogel exhibits exceptional mechanical strength (withstanding >5000 times its own weight), endowing the composite PCMs with superior shape stability. This hierarchical framework, comprising aerogel network and hollow P-ZIF-8 microshells, provides a dual encapsulation effect and achieves outstanding encapsulation capability (97.6 %) and latent heat storage density (190.0 J/g), maintaining thermal durability and stability over 200 heating-cooling cycles. The MXene and P-ZIF-8 microshells synergistically enhance solar-thermal harvesting and energy conversion in composite PCMs, achieving a solar-thermal conversion efficiency of 98.3 % and outputting 442.1 mV and 69.1 mA in a solar-thermal-electric generator under 500 mW/cm 2 . The P-ZIF-8 microshells and MXene both provide physical barriers and catalytic charring effect, markedly enhancing the flame retardancy of the composite PCMs with peak heat release rate (pHRR) and total heat release (THR) significantly reduced by 31.1 % and 17.1 %, respectively. This work offers a versatile pathway for multifunctional PCMs that simultaneously meet the needs of thermal energy storage, solar harvesting and fire safety.
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高影响因子
JOURNAL OF MEMBRANE SCIENCE
·
2025
·
IF 9
Jinhuai Hua,Rui Yao,Haonan Xu,Wenbin Zhao,Yuping Zhou,Hua Jin,Yanshuo Li
This study addresses the challenges of bio-butanol recovery by synergizing innovative module design with advanced mixed matrix membranes (MMMs) for enhanced pervaporation (PV) efficiency. ZIF-8 nanoparticles (14–120 nm) were integrated into a polymethylphenylsiloxane (PMPS) matrix to fabricate ZIF-8/PMPS MMMs on flat-sheet Al 2 O 3 supports, for efficient n-butanol separation via pervaporation. The optimized 14 nm-ZIF-8/PMPS MMMs (13.0 wt% loading) exhibited optimal performance, achieving a total flux of 925.86 g m −2 h −1 and a separation factor of 37.65 for 1 wt% n-butanol/water mixtures at 40 °C, enabling stable operation over 600 h. Key factors included the improved hydrophobicity, reduced interfacial voids, and enhanced surface roughness. A novel plate-and-frame module was engineered to address scalability challenges, increasing packing density from 5 to 55 m 2 /m 3 while mitigating concentration polarization and enhancing mass transfer under dynamic flow conditions. The module's compact design, combined with the mechanical robustness of Al 2 O 3 supports and the compatibility of ZIF-8/PMPS membranes, demonstrates industrial viability.
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高影响因子
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
·
2025
·
IF 5.4
Mengshi Chen,Zihan Kang,Jingjing Ning,Ni Qin,Dinghua Bao
A novel method was established to create ZnO/ZIF-8 core/shell heterostructured film piezo-photocatalysts for highly efficient removal of pollutants from water. This method was inspired by distinctive pore structure of ZIF-8 and has the advantage of simple and quick synthesis. In this work, ZnO/ZIF-8 heterostructure thin films were created by growing ZIF-8 metal organic framework in-situ on inverse opal structure ZnO films, which also served as the porous template and zinc source of ZIF-8 simultaneously. Thus, the ZnO/ZIF-8 core/shell heterostructure is composed of ZnO core and ZIF-8 shell. The inverse opal structure enhances the process of light absorption, and the heterostructure is crucial for enhancing the carrier concentration. The ZnO/ZIF-8 heterostructure films exhibit significant degradation capacity towards Rhodamine B (RhB) and tetracycline (TC). Under UV light and ultrasound, the degradation efficiency of ZnO/ZIF-8 heterostructure is much higher than that of ZnO film and ZIF-8 film for RhB solution, indicating that the heterostructure films have a great potential for use in the field of water pollution prevention. This study not only presents an effective method for quickly creating heterostructures, but also demonstrates a path for improving the piezo-photocatalytic efficiency by manipulating the morphology and structure of ZnO/ZIF-8.
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高影响因子
危险品化学品经营许可证（带存储）