JOURNAL OF ANALYTICAL CHEMISTRY
·
2020
·Vol. 75
·期 2
·219-224
·
IF 0.84
Liang Demin,Gao Yihan,Zheng Saijing,Li Gang,Wu Da,Shen Yi
Abstract A simple and rapid gas chromatographic–mass spectrometric (GC–MS) method using selected ion monitoring mode was developed for simultaneous determination of propylene glycol, glycerol and lactic acid in rat plasma and serum. The method employed a single-step derivatization using bis(N,O-trimethylsilyl) trifluoroacetamide with trimethylchlorosilane and required only a small amount of plasma or serum (100 μL). The calibration curves showed linearity with the correlation coefficients of 0.996–0.999. To validate the method, the intra- and inter-day repeatability of the proposed method in rat plasma was evaluated. Recovery was assessed by the standard addition method. To test the applicability of the method, twenty plasma samples in two different time points were analyzed and levels of both propylene glycol and lactic acid in plasma were found to increase after exposure to the propylene glycol aerosol (500 mg/kg). With satisfactory repeatability and recovery the proposed GC–MS method can be successfully applied for analysis of plasma and serum samples.
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SENSORS AND ACTUATORS B-CHEMICAL
·
2017
·
IF 5.401
Fengdong Qu,Bingxue Zhang,Xinxin Zhou,Huifang Jiang,Chuanxi Wang,Xiaohua Feng,Chunjie Jiang,Minghui Yang
The utilization of metal-organic frameworks (MOFs) as precursors or templates to design synthesize nanostructured metal oxides has attracted intense interest for their great potential applications in gas separation/storage, drug delivery, catalysis device, gas sensors, etc. In this paper, porous double-shelled nanocages (NCs), namely ZnO/Ni 0.9 Zn 0.1 O double-shelled nanocages (DSNCs), were synthesized simply through a metal-organic frameworks (MOFs) route. The ZIF-8 rhombododecahedron was first synthesized and then transformed into ZIF-8/Ni-Zn layered double hydroxides (LDH) precursor. Finally, the ZnO-inner/Ni 0.9 Zn 0.1 O-outer DSNCs were obtained through thermal annealing of the as-prepared precursor in air. The ZnO/Ni 0.9 Zn 0.1 O DSNCs, when utilized as gas sensing material, exhibited high sensitivity and selectivity towards xylene. Besides, enhanced gas sensing properties of ZnO/Ni 0.9 Zn 0.1 O DSNCs were observed when compared with ZnO NCs. Such outstanding gas sensing performance of the ZnO/Ni 0.9 Zn 0.1 O DSNCs benefits from their high porosity, large specific surface area, and synergistic effect of ZnO and Ni 0.9 Zn 0.1 O.
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Nanoscale
·
2020
·Vol. 12
·期 47
·24146-24161
·
IF 6.895
Shikai Liu,Wenting Li,Shuming Dong,Fangmei Zhang,Yushan Dong,Boshi Tian,Fei He,Shili Gai,Piaoping Yang
Gasotransmitters with high therapeutic efficacy and biosafety have been drawing the attention of researchers. Nevertheless, how to effectively deliver gases to and precisely control their generation at the lesion as well as integrate them with other therapies to realize precision therapy have remained elusive. Herein, we report a versatile Cu2+-initiated nitric oxide (NO) nanocomposite for multimodal imaging-guided synergistic chemodynamic/photodynamic/gas therapy. After the nanomedicine was ingested by tumor cells, the acidic tumor microenvironment accelerated the decomposition of CuO2 and simultaneously triggered the Fenton-like catalytic reaction of Cu2+ and H2O2 to produce highly toxic ˙OH. By virtue of the NO generation and glutathione depletion, UMNOCC-PEG can relieve the antioxidant capacity and hypoxia of the tumor to improve the efficiency of chemodynamic therapy (CDT) and photodynamic therapy (PDT). Importantly, NO and reactive oxygen species (ROS) can generate reactive nitrogen species (RNS), which can result in DNA damage, further improving the therapeutic effect (cell apoptosis rate up to 93.4%). Moreover, the inherent properties of lanthanide ions endow UMNOCC-PEG with upconversion luminescence (UCL), CT and MRI trimodal imaging capability, achieving precise cancer treatment. By taking advantage of these features, the strategy developed here may provide a promising application foreground to conquer malignant tumors.
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DOI
PubMed
高影响因子
Science China-Chemistry
·
2021
·Vol. 64
·期 12
·2218-2229
·
IF 9.445
Ye Jiamin,Fu Qinrui,Liu Luntao,Chen Lanlan,Zhang Xuan,Li Qingqing,Li Zhi,Su Lichao,Zhu Rong,Song Jibin,Yang Huanghao
Varieties of contrast agents have been developed for photoacoustic (PA) and ultrasound (US) imaging of cancers in vivo . However, access of traditional contrast agents into the sites of tumors has been principally through passive infiltration without any external force, preventing their deep penetration into the tissues of the tumors, and hindering the use of PA and US for deep tumor imaging. The concept of micro/nanomotors has been the focus of increasing attention as active theranostic agents due to their active movement in particular fluids, thereby conducting assigned tasks. Herein, US-propelled Janus mesoporous SiO 2 partially coated gold nanorods (Au NR-mSiO 2 ) were fabricated for deep tumor NIR-II PA imaging and synergistic sonodynamic-gas therapy. Following US irradiation, 2,2-azobis[2-(2-imidazolin-2-yl) propane] dihydrochloride (AIPH) loaded in mSiO 2 (Au NR-mSiO 2 /AIPH) generated N 2 microbubbles with high efficiency to achieve nanomotor drive. Due to the deep penetration of US, the nanomotors exhibited a capability to travel deep within sites of tumors, providing enhanced PA/US imaging inside the tumors. Furthermore, the nanomotor based cancer therapy was demonstrated through synergistic N 2 gas and sonodynamic therapy. The US-propelled nanomotors demonstrated a novel strategy for the simultaneous PA/US dual imaging deep within tumor tissues and precise therapy of large tumors.
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Frontiers of Environmental Science & Engineering
·
2020
·Vol. 15
·期 4
·1-13
·
IF 4.053
Feng Haoran,Liu Min,Zeng Wei,Chen Ying
The present study reports the use of the O 3 /H 2 O 2 process in the pretreatment of the mother liquor of gas field wastewater (ML-GFW), obtained from the multi-effect distillation treatment of the gas field wastewater. The range of optimal operation conditions was obtained by single-factor experiments. Response surface methodology (RSM) based on the central composite design (CCD) was used for the optimization procedure. A regression model with Total organic carbon (TOC) removal efficiency as the response value was established ( R 2 = 0.9865). The three key factors were arranged according to their significance as: pH>H 2 O 2 dosage>ozone flow rate. The model predicted that the best operation conditions could be obtained at a pH of 10.9, an ozone flow rate of 0.8 L/min, and H 2 O 2 dosage of 6.2 mL. The dosing ratio of ozone was calculated to be 9.84 mg O 3 /mg TOC. The maximum removal efficiency predicted was 75.9%, while the measured value was 72.3%. The relative deviation was found to be in an acceptable range. The ozone utilization and free radical quenching experiments showed that the addition of H 2 O 2 promoted the decomposition of ozone to produce hydroxyl radicals (·OH). This also improved the ozone utilization efficiency. Gas chromatography-mass spectrometry (GC-MS) analysis showed that most of the organic matters in ML-GFW were degraded, while some residuals needed further treatment. This study provided the data and the necessary technical supports for further research on the treatment of ML-GFW.
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ANALYTICAL CHEMISTRY
·
2018
·
IF 6.042
Yuan Yang,Qing Tan,Yao Lin,Yunfei Tian,Li Wu,Xiandeng Hou,Chengbin Zheng
Speciation analysis of mercury in hair facilitates accurate evaluation of mercury exposure to humans and insights into the intertransformation of different mercury species in the human body. However, conventional hyphenated techniques used for mercury speciation analysis usually require expensive instruments and a complex interface. In this work, a compact and miniaturized point discharge (PD) atomic emission spectrometer was utilized as a detector of gas chromatography for the speciation analysis of mercury. Mercury species extracted from hair were derivatized to their volatile species with NaBEt4 and subsequently preconcentrated by headspace solid-phase microextraction (HS-SPME) prior to their speciation analysis. Under the optimized conditions, limits of detection of 0.35 μg kg–1 (0.035 ng) and 1.0 μg kg–1 (0.10 ng) were obtained for IHg and MeHg, respectively, with a relative standard deviation (RSD) of better than 3.5%. Because of the compact and miniature conformation, high excitation capability, low power consumption of PD-OES, and efficient preconcentration of mercury species by HS-SPME, the proposed system not only overcomes the shortcomings associated with the conventional hyphenated techniques but also provides several unique advantages, including significant simplification of experimental setup, reduction of dead volume, and improvement of sensitivity. The accuracy of this system was validated by speciation analysis of mercury in a Certified Reference Material (GBW09101b, human hair) and 10 human hair samples collected from different people in the population.
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PubMed
高影响因子
PROGRESS IN ORGANIC COATINGS
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2021
·
IF 5.161
Haoyu Ma,Pengjian Gong,Yunjiao Qiao,Yajiang Huang,Chul B. Park,Hong Jiang,Guangxian Li
Dual fluorescence design based on chemical coating and physical staining was successfully applied in revealing the multi-phase and multi-scale structure simultaneously in nanocomposite foams for the first time (that is nanometer-scale solid phase fillers selectively located chemical coating fluorescence, micrometer-scale solid phase cell walls selectively located physical staining fluorescence and air phase bubbles selectively located no fluorescence). The hybrid fluorescence modification method enables us to selectively locate different fluorescence dyes on nanofiber surface and in polymer matrix. Furthermore, quantitative analysis of the three-dimensional (3D) nanofiber network structure in nanocomposite foams is studied in-depth via numerical reconstruction. The evolution of 3D nanofiller network structure in multi-phase and multi-scale nanocomposite foams is demonstrated via both experimental visualization and numerical calculation. It is found that the average shortest nanofiber distance decreases with increasing cell wall thickness and with decreasing air content. Therefore, the dual fluorescence design exploring 3D functional filler network structure in complicated multi-phase and multi-scale nanocomposite foams greatly helps researchers study the structure-performance relationship of multi-functional materials with nanoscale functional fillers.
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ACS Sustainable Chemistry & Engineering
·
2025
·
IF 7.3
Hao Qin,Mintao Pang,Fanjing Wei,Zhiguo Yuan,Weizhou Jiao,Guisheng Qi,Youzhi Liu
Gas absorption plays a vital role in environmental protection and resource recovery but remains hindered by low mass transfer efficiency, large equipment size, and environmental concerns of conventional solvents. To address these challenges, this work establishes a generalizable framework that couples solvent innovation with equipment enhancement to advance sustainable process intensification. Specifically, room-temperature nonionic deep eutectic solvents (DESs) are rationally designed through precursor collection, fusion property and EHS evaluation, and solid–liquid equilibrium calculations, yielding 313 feasible DES combinations. Considering five composition ratios, 1565 DES candidates are generated, from which COSMO-RS screening identifies three promising diglyme-based systems for CO2 absorption. Their absorption behavior is experimentally validated in a rotating packed bed (RPB), confirming both the reliability of the computational screening and the significant intensification effect of high-gravity field. Mechanistic insights are further obtained from σ-profiles, interaction energy calculations, and quantum chemical analyses, revealing that van der Waals interactions dominate CO2-DES binding, while hydrogen bonding drives DES formation. These results not only validate the consistency of solvent design and experimental outcomes but also highlight the synergistic effect of integrating solvent design with high-gravity technology. Overall, the study demonstrates a versatile methodology for intensifying gas absorption, with CO2 capture as a representative application.
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高影响因子
MATERIALS SCIENCE IN SEMICONDUCTOR PROCESSING
·
2025
·
IF 4.6
Pengfei Tian,Yunan Shen,Yuzhe Hua,Zilong Chen,Zhifan Chen,Qingjie Guo,Hongjing Tian
Calcium lignosulfonate, an important natural anionic surfactant widely used in chemical, agricultural and construction applications, was employed to enhance the desulfurization performance of Ca(OH) 2 by adjusting its crystal growth at the atomic level. In the digestion of CaO, calcium lignosulfonate was selectively adsorbed onto the 101 surface of Ca(OH) 2 crystal by the interaction between the sulfonic acid group of calcium lignosulfonate and Ca(OH) 2 surface. The specific adsorption was proved to inhibit the growth of the 101 crystal surface owing to the steric hindrance and electronic interactions. DFT calculations show that the adsorption energy is −1.70 eV, and the change in free energy is negative, indicating spontaneous adsorption. By XRD and SEM characterization results and DFT simulation results, while boost the Ostwald ripening of the 001 surface to form the ultrathin nanosheets with a thickness of 16–21 nm. PDOS simulation results testified that the transferring of lone pair electrons from 2p orbital to the empty 3d-orbitals of calcium and the formation of Ca-O bond because of 0.08 Ha blue shift and broadening of the 2p-orbitals of oxygen. Additionally, the calcium lignosulfonate (CLS) modified Ca(OH) 2 exhibited the increase of BET surface area by 62 % from 30.09 m 2 /g to 48.76 m 2 /g and developed a mesoporous structure with the pore volume of 0.248 cm 3 /g. Consequently, the sulfur capacity of Ca(OH) 2 –15.62 mg/g in comparison to pristine Ca(OH) 2 without CLS, while the penetration times for desulfurization experiments increased from 3300 s to 7600 s.
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高影响因子
EUROPEAN POLYMER JOURNAL
·
2025
·
IF 6.3
Sheng-Li Han,Hui-Qin Zhang,Feng Yang,Yun Liu,Hong-Hui Shu,Lian-Bing Zhang,Cheng-Mei Liu
Value-added utilisation of industrial and agricultural residues is an attractive strategy to address resource shortages and promote greener chemical production. PH 3 , a hazardous by-product of hypophosphite preparation, requires careful handling due to its high toxicity and flammability. In this study, we developed a method to convert PH 3 tail gas into hydrolytically stable single-ion conducting polymers (SICPs) with potential recyclability after service. Oligoether-containing styrenic monomers (VBP-nEO) were synthesised from 4-vinylbenzyl(bis(hydromethyl))phosphine oxide (VBzHPO) via Williamson etherification in water, and the resulting functional monomers underwent conventional free-radical polymerisation to produce both homo- and co-polymers. The water-soluble homopolymers exhibited high hydrolysis resistance under both acidic and basic conditions because the phosphorus atom was covalently bonded to three substituents through P–C bonds. The co-polymers containing dissociable lithium salt segments exhibited promising ionic conductivity at moderate temperatures (4.48 × 10 −6 S/cm at 90 °C), which depended on the ethylene oxide (EO) content and EO/Li + ratio within the co-polymers. All co-polymers showed high thermal stability, with initial decomposition temperatures exceeding 300 °C and calculated LOI values above 21 %.
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高影响因子
Petroleum Science
·
2025
·
IF 6.1
Li-Yao Dai,Jin-Sheng Sun,Kai-He Lv,Ying-Rui Bai,Bo Liao,Dong-Qing Yang,Chao-Zheng Liu,Mei-Chun Li
Fractures in geological formations, which are commonly encountered during oil and gas exploration, pose significant challenges by facilitating fluid loss and reducing wellbore stability. Polymer gels hold significant promise as lost circulation materials due to their excellent deformability under pressure and self-adaptability. However, conventional gels face certain limitations, such as poor retention of gel-forming suspensions in fractures, low structural strength, and instability at high temperatures. These issues result in low pressure-bearing capacity and, consequently, reduced effectiveness in sealing formation fractures. This study presents the synthesis of a supramolecular polymer gel (SPG) composed of acrylamide (AM), 2-acrylamide-2-methylpropanesulfonic acid (AMPS), divinylbenzene (DVB), polyvinyl alcohol (PVA), TEMPO-oxidized cellulose nanofibers (CNFs), and laponite via in situ radical polymerization. Due to the synergistic effects of hydrogen bonding and electrostatic interactions, the supramolecular polymer gel-forming suspension exhibits high retention capacity in fractures. The as-synthesized gels demonstrate remarkable temperature resistance and high mechanical strength, attributed to covalent bonding, multiple hydrogen bonding, and electrostatic interactions, along with the high aspect ratio and modulus of CNFs and laponite. This study broadens the application scope of CNFs, laponite, and SPGs, offering a novel approach for the efficient development of unconventional oil and gas resources.
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INTERNATIONAL JOURNAL OF HYDROGEN ENERGY
·
2025
·
IF 8.3
Bowen Yang,Yangyang Long,Feng Chen,Jiabao Wang,Zhipeng Wang,Ziqiang Zhang,Yanfei Wang,Weihua Zou,Yeguang Zhang,Peng Wang,Zili Zhan,Feihu Li
Hydrogen sensor based on proton exchange membrane fuel cells (PEMFCs) was one of the most extensively studied types. However, traditional Pt/C based electrodes suffered from several drawbacks, including high cost, low catalytic efficiency for oxygen reduction reaction (ORR) and slow reaction kinetics. Herein, we developed a quasi PEMFCs hydrogen sensor utilizing MnO 2 as cathode catalyst, where the electrochemical signal was generated via the direct MnO 2 redox reaction with hydrogen, replacing the ORR process. Membrane electrode assemblies (MEAs) were successfully fabricated incorporating α-MnO 2 , β-MnO 2 , and δ-MnO 2 polymorphs. The β-MnO 2 -based sensor demonstrated best sensing performance with a maximum sensitivity of 96 nA/ppm, a 34-fold enhancement over conventional dual-platinum electrochemical sensors, under the optimized volume ratio of catalyst ink (ethylene glycol: Nafion solution: water = 1:4:4). Moreover, the β-MnO 2 -based sensor exhibited significantly superior response and recovery speed. This strategy provided an effective approach for the commercialization of next generation PEMFCs-type hydrogen sensors.
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