ACS Applied Bio Materials
·
2018
·
IF 0
Yang Zhang,Guohua Jiang,Wenjie Hong,Mengyue Gao,Bin Xu,Jiangying Zhu,Gao Song,Tianqi Liu
Herein, an NIR-responsive polymeric microneedle (MN) system incorporated with metformin-loaded and polydopamine/lauric-acid-coated (PDA/LA-coated) hollow mesoporous SiO2 has been developed for transdermal delivery of antidiabetic drug (metformin). First, an antidiabetic drug was loaded within hollow mesoporous SiO2 nanoparticles (HMSNs) by a diffusion method. Then, PDA as photothermal conversion agent and lauric acid (LA) as phase change material (PCM) were coated onto the HMSN to form NIR-responsive drug nanocarriers. Finally, these metformin-loaded and PDA/LA-coated HMSNs were encapsulated into poly(vinylpyrrolidone) (PVP) MNs. After insertion into skin tissue, LA could melt with the photothermal conversion of PDA under NIR light, thus enabling release of encapsulated metformin from MNs. The in vivo release behavior of metformin from MNs into skin was further studied to investigate its hypoglycemic effect on diabetic rats. Compared with the subcutaneous injection of metformin, the bioavailability of MN–NIR groups was 95.8 ± 2.7%. The antidiabetic drug can be precisely released by adjustment of exposure time and power densities of NIR light.
✓ 已验证
产品关联
DOI
PubMed
JOURNAL OF HAZARDOUS MATERIALS
·
2015
·
IF 4.529
Chao Shan,Zhiyao Ma,Meiping Tong
Poly(1-vinylimidazole)-grafted Fe 3 O 4 @SiO 2 magnetic nanoparticles (FSPV) were developed to remove both free Cd(II) and nitrilotriacetic acid (NTA) complexed Cd(II) from water. The adsorption capacity of NTA-complexed Cd(II) (42.1 mg/g) was larger than that of free Cd(II) (24.8 mg/g). Free Cd(II) and NTA-complexed Cd(II) could be reduced from 50 μg/L to below 5 μg/L within 10 and 20 min, respectively. FSPV could effectively remove trace free and NTA-complexed Cd(II) over broad pH ranges of 5–10 and 5–11, respectively. Moreover, the presence of seven coexisting ions (up to 100 mM) including four cations (Na + , K + , Ca 2+ , and Mg 2+ ) and three anions (Cl − , NO 3 − , and SO 4 2− ) all slightly promoted the removal of both free and NTA-complexed Cd(II) onto FSPV. The removal of free Cd(II) or NTA-complexed Cd(II) was not obviously affected by the presence of Ni(II) and Co(II) (50 μg/L), humic acid (up to 3 mg/L as TOC) or alginate (up to 8 mg/L as TOC). In addition, FSPV could be regenerated with 10 mM HCl in 10 min, and the removal of both types of Cd(II) maintained above 95% in five consecutive adsorption/regeneration cycles. Therefore, FSPV could be utilized as promising adsorbent for both free and NTA-complexed Cd(II).
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Catalysis Science & Technology
·
2014
·Vol. 5
·期 1
·405-414
·
IF 4.76
Hongmei Liu,Kai Tao,Chunrong Xiong,Shenghu Zhou
In this work, Pd–NiO@SiO2 core–shell mesoporous nanocatalysts with ~4 nm Pd–NiO heteroaggregate nanoparticle cores and ~17 nm mesoporous silica shells were successfully synthesized by a sol–gel method. The surfactant-capped PdNi alloy nanoparticles were coated with SiO2 through hydrolysis of tetraethylorthosilicate to obtain PdNi@SiO2 nanoparticles, and the mesoporous Pd–NiO@SiO2 core–shell nanocatalysts were formed after removal of surfactants by calcination at 500 °C and subsequent H2 reduction at 200 °C. The characterization results by XRD, TEM and BET revealed that Pd–NiO@SiO2 nanocatalysts were highly stable with the maintenance of intact core–shell structures under high-temperature thermal treatments. The Pd–NiO@SiO2 nanocatalysts illustrated a superior catalytic performance for p-chloronitrobenzene hydrogenation with H2 to the control Pd@SiO2 nanocatalysts. The catalytic performance enhancement of Pd–NiO@SiO2 nanocatalysts is ascribed to the strong interaction between Pd and NiO in the cores, where the interfaces may be beneficial for hydrogenation reactions.
✓ 已验证
产品关联
DOI
高影响因子
BIOSENSORS & BIOELECTRONICS
·
2015
·
IF 6.409
Taotao Feng,Xiuwen Qiao,Haining Wang,Zhao Sun,Chenglin Hong
A sandwich-type electrochemical immunosensor was developed for sensitive detection of carcinoembryonic antigen (CEA) by using ferroferric oxide@silica–amino groups (Fe 3 O 4 @SiO 2 –NH 2 ) as carriers and gold nanoparticles–graphene oxide (GO–AuNPs) as platform. The Fe 3 O 4 @SiO 2 –NH 2 surface was used as linked reagents for co-immobilization of ferrocenecarboxylic acid (Fc-COOH) and secondary anti-CEA (Ab 2 ) to prepare the signal probe , and it also could hasten the decomposition of hydrogen peroxide (H 2 O 2 ) to amplify signals. Differential pulse voltammetry (DPV) was successfully used to quantify CEA. Under the optimized conditions, the designed immunosensor shows an excellent analytical performance wide dynamic response range of CEA concentration from 0.001 ng mL −1 to 80 ng mL −1 with a relatively low detection limit of 0.0002 ng mL −1 ( S / N =3), and high specificity and good reproducibility. The proposed immunosensor was successfully used to determine CEA in spiked human serum samples.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
APPLIED SURFACE SCIENCE
·
2017
·
IF 3.387
Qiang Huang,Meiying Liu,Junyu Chen,Qing Wan,Jianwen Tian,Long Huang,Ruming Jiang,Fengjie Deng,Yuanqing Wen,Xiaoyong Zhang,Yen Wei
The removal of organic dyes using functionalization SiO 2 composites (denoted as SiO 2 -PDA-CSH) were prepared via a facile method that combined with mussel inspired chemistry and Kabachnik–Fields (KF) reaction. The size and surface morphology, chemical structure, thermal stability, surface charging property, and elemental composition were evaluated by means of transmission electron microscope (TEM), Fourier transform infrared spectroscopy (FT-IR), thermogravimetric analysis (TGA), zeta potential, and X-ray photoelectron spectroscopy (XPS), respectively. The results demonstrated that the organic functional groups can be successfully introduced onto the surface of SiO 2 microspheres through the combination of mussel inspired chemistry and KF reaction. The removal of cationic dye methylene blue (MB) by the raw SiO 2 and SiO 2 -PDA-CSH composites was examined and compared using a series of batch adsorption experiments. The results suggested that SiO 2 -PDA-CSH composites had a 3-fold increase in the adsorption capacity towards MB than that of pure SiO 2 microspheres and the adsorption process was dependent on the solution pH. According to the adsorption kinetics, the adsorption of MB onto SiO 2 -PDA-CSH composites was well described by pseudo-second-order kinetic model. The equilibrium data were fitted with Langmuir and Freundlich isotherm models with R 2 = 0.9981 and R 2 = 0.9982, respectively. The maximum adsorption capacity from Langmuir isotherm was found to be 688.85 mg/g. The adsorption thermodynamics was also investigated in detailed. The parameters revealed that the adsorption process was spontaneous and endothermic in nature. The adsorption mechanism might be the synergistic action of physical adsorption of SiO 2 -PDA-CSH particles and electrostatic interaction between the MB and functional groups on the surface of SiO 2 -PDA-CSH composites, including sulfydryl, amino, aromatic moieties, and phosphate groups. Taken together, we developed a novel and facile strategy for the surface modification of SiO 2 to achieve high adsorption towards MB based on the mussel inspired chemistry and multicomponent KF reaction. More importantly, this strategy could be easily extended for fabrication of many other high efficient adsorbents due to the universality of mussel inspired chemistry and various multicomponent reactions based on amino groups. Therefore, this work will open a new avenue and direction for the environmental applications of mussel inspired chemistry.
✓ 已验证
产品关联
DOI
高影响因子
ACS Applied Materials & Interfaces
·
2017
·
IF 7.504
Cuiqing Wu,Qi Liu,Rongrong Chen,Jingyuan Liu,Hongsen Zhang,Rumin Li,Kazunobu Takahashi,Peili Liu,Jun Wang
Superhydrophobic coatings are highly promising for protecting material surfaces and for wide applications. In this study, superhydrophobic composites, comprising a rhombic-dodecahedral zeolitic imidazolate framework (ZIF-8@SiO2), have been manufactured onto AZ31 magnesium alloy via chemical etching and dip-coating methods to enhance stability and corrosion resistance. Herein, we report on a simple strategy to modify hydrophobic hexadecyltrimethoxysilan (HDTMS) on ZIF-8@SiO2 to significantly improve the property of repelling water. We show that various liquids can be stable on its surface and maintain a contact angle higher than 150°. The morphologies and chemical composition were characterized by means of scanning electron microscopy (SEM) and Fourier transform infrared spectroscopy (FI-IR). In addition, the anticorrosion and antiattrition properties of the film were assessed by electrochemical impedance spectroscopy (EIS) and potentiodynamic polarization and HT, respectively. Such a coating shows promising potential as a material for large-scale fabrication.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
RSC Advances
·
2016
·Vol. 6
·期 80
·76867-76873
·
IF 3.289
Yunfei Zhang,Bo Yang,Jinhong Fan,Luming Ma
In this study, abrasives-reinforced metal matrix composites (MMCs) with a microscale size synthesized by ball milling (BM) could achieve highly active and stable dechlorination efficiency for aqueous 2-chlorophenol (2-CP). The preparation process of this composite via BM was optimized to obtain a high degradation efficiency, especially for the effect of the abrasives including B4C, SiC, α-Al2O3, SiO2, Fe3O4 and Na2SO4. The results showed that the hardness of the abrasives in the Fe-based MMCs was closely related with their dechlorination performance. Subsequently, the optimal abrasive, i.e. SiO2 was further investigated for its proper milling conditions with zero-valent iron (ZVI) particles including optimal SiO2 size, SiO2 loading, milling time, and the dosage of the process control agent (PCA). Additionally, the influence of other metal categories including Al and Si was also investigated for dechlorination; and their low reaction efficiencies were closely related with their passivating film. Finally, the longevity test suggested that the decreased reactivity of the SiO2–Fe MMC during the storage in air could be recovered when consecutively used, mainly due to the promoting effects of the inherent structure of SiO2–Fe MMC with the Fe/C and Fe/SiO2 interfaces, as well as the effective regeneration of the reactive sites by continuous iron dissolution.
✓ 已验证
产品关联
DOI
高影响因子
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
·
2017
·
IF 2.714
Yi Shang,Zhihai Cao,Hangnan Chen,Yangyi Sun,Jia Yao,Lin Yang,Dongming Qi,Ulrich Ziener
In our previous paper, we reported the synthesis of easily recyclable and highly active rice roll-like (RR-like) Au/SiO 2 nanocatalysts (NCs) in inverse miniemulsions [Colloids Surf. A 517, 2017, 52–62]. In the present contribution, the influences of three key synthesis parameters, including the 3-aminopropyltriethoxysilane (APTES) content, reaction temperature, and urea amount, on the particle properties of the Au/SiO 2 NCs were systematically investigated. The role of these synthesis parameters in the formation of SiO 2 nanosupports and Au nanoparticles (NPs) was discovered. The RR-like SiO 2 nanosupports could only be formed in the systems within the range of 20–80 mol% of APTES content, at reaction temperatures above 60 °C, and with more than 0.72 mg of urea. The AuCl 4 − ions could be immobilized onto the aminopropyl-functionalized SiO 2 nanosupports through a coordination interaction. The immobilized ions were reduced by the aminopropyl groups at elevated temperatures. The APTES content and reaction temperature play an important role in controlling the particle size and its distribution of Au NPs. The catalytic activity of Au/SiO 2 NCs depends significantly on the APTES content. The RR-like Au/SiO 2 NCs with smaller immobilized Au NPs and higher specific surface area display higher catalytic activity towards hydrogenation of p -nitrophenol.
✓ 已验证
产品关联
DOI
高影响因子
HIGH PERFORMANCE POLYMERS
·
2016
·
IF 1.045
Yang Liu,Pengfei Huo,Jiannan Ren,Guibin Wang
A series of novel organic–inorganic hybrid proton exchange membranes (PEMs) were prepared from the sulfonated poly(arylene ether sulfone) with 4-amino phenyl pendant groups (Am-SPAES), (3-isocyanatopropyl) triethoxysilane (ICPTES), and 3-(trihydroxysilyl) propane-1-sulfonic acid with covalent bonds to form network using a sol-gel method. The obtained cross-linked hybrid membranes (Am-SPAES/I-SiO2-S) displayed excellent solvent resistance and thermal and mechanical stability. The Am-SPAES/I-SiO2-S membranes with cross-linking network exhibited a higher proton conductivity (0.043 S cm−1 at 20°C) than PEMs without covalent bonds (Am-SPAES/SiO2-S) and the swelling ratio maintained below 17.00% even at 100°C. Most importantly, all of the obtained membranes showed considerably lower methanol permeability than that of Nafion 117. In addition, the chemical structures and morphologies of the hybrid membranes were characterized by Fourier transform infrared spectroscopy and scanning electron microscopy, respectively.
✓ 已验证
DOI
高影响因子
POLYMER COMPOSITES
·
2024
·
IF 4.8
Lin Jiang,Yunhui Yang,Jie Sheng,Yongzhe Li,Zhengqiang Huang,Jiquan Li,Tie Geng
Poor interfacial compatibility is a key factor limiting the mechanical properties of basalt fiber reinforced polymer composites (BFRPs). Constructing hybrid interfaces that combine rigid nanoparticles with flexible sizing agents presents a promising strategy to enhance these properties. In this study, we first identified the most suitable coupling agent from a series of candidates, including amino, epoxy, and methacryloxy functional groups. Using the selected coupling agent as a flexible sizing agent and inorganic nano-SiO 2 as the rigid component, two types of interfaces were developed: a homogeneous organic/inorganic hybrid interface and a gradient-modulus structure, which were fabricated via direct deposition and in-situ growth methods, respectively. The results demonstrated that BFRPs with gradient modulus interface effectively absorb and dissipate crack energy under loading, resulting in significantly improved mechanical properties. The interlaminar shear strength (ILSS), tensile strength, and flexural strength increased to 56.24, 541, and 793 MPa, respectively, representing improvements of 40.81%, 15.35%, and 32.38%. Fracture morphology analysis further confirmed the reinforcement mechanism of the “rigid-flexible” hybrid interfaces. This work can provide valuable insights for developing high-performance basalt fiber-reinforced composites. Highlights Suitable silane coupling agent was selected for basalt fiber (BF) reinforced epoxy composites. Organic/inorganic hybrid and gradient modulus interfaces were established. Uniformly distributed SiO 2 and fully covered silane boosts interfacial bonding. Interfacial, tensile and flexural properties of modified BFRPs all improved.
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF ALLOYS AND COMPOUNDS
·
2025
·
IF 6.3
Keyi Gu,Yongmin Duan,Shugang Li,Ying Tian,Juan Du,Junjie Zhang
In recent years, inorganic perovskite quantum dots (PQDs) have garnered significant attention, but the photoluminescence (PL) properties and stability of red-emitting PQDs need to be further enhanced. In this work, the precipitation of CsPb(Br/I) 3 quantum dots into borosilicate glass was effectively enabled by the high-temperature melt-quenching method. With the B 2 O 3 /SiO 2 ratio increased, the glass network structure gradually loosened, which enhanced the precipitation of PQDs. Simultaneously, the PL intensity of CsPb(Br/I) 3 PQDs glass increased, with a near twentyfold rise in the photoluminescence quantum yield (PLQY). The variable temperature test of PQDs glass shows that PQDs glass has good thermal stability. Finally, a red-emitting LED and a WLED were prepared by using the prepared red-emitting CsPb(Br/I) 3 PQDs glass. This paper serves as a reference for incorporating red-emitting CsPb(Br/I) 3 PQDs glass into WLED development.
✓ 已验证
产品关联
DOI
高影响因子
RESEARCH ON CHEMICAL INTERMEDIATES
·
2024
·
IF 2.8
Tong Jiale,Huang Yeyin,Tang Wanjun,You Qingliang,Xie Guangyong
This work aims at developing a customized ammoxidation catalyst through optimizing the metal oxide content in CrVO 4 /SiO 2 catalysts. Various amounts of Cr–V–O with 1:1 molar ratio of Cr/V were successfully loaded on SiO 2 via spray-drying method with colloidal silica as the binder. Polarized light microscope illustrated that the CrVO 4 /SiO 2 particles presented as well dispersed microspheres in the microsize (20–80 μm). X-ray diffraction spectra confirmed the formation of monoclinic CrVO 4 phase wherein the metal oxide content was ranged from 30 to 70 weight percent. FT-IR spectra indicated that the introduction of metal oxide had no obvious effects on the skeletal structure of SiO 2 . X-ray photoelectron spectroscopy analysis revealed that the valence state of V and Cr was hardly affected with increasing the metal oxide content. Performances of the obtained CrVO 4 /SiO 2 catalysts with different metal oxide contents were investigated via the ammoxidation of a model compound, namely para-chlorotoluene (PCT) to para-chlorobenzonitrile (PCBN). A maximum conversion of 99.6% of PCT and 86.5% yield and 86.8% selectivity to PCBN have been obtained over the CrVO 4 /SiO 2 catalyst with 60% weight of metal oxides at a temperature of 410 °C, n( PCT): n (NH 3 ): n (air) = 1:3:15 and reaction load = 0.13 g/gCat·h. In addition, this catalyst was efficient and selective toward ammoxidation reactions of toluene, ortho- and meta-chlorotoluenes. Graphical abstract
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）