JOURNAL OF BIOMATERIALS SCIENCE-POLYMER EDITION
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2016
·
IF 1.733
Tingting Xu,Fang Peng,Tao Zhang,Bo Chi,Hong Xu,Chun Mao,Shuaihui Feng
Poly(γ-glutamic acid) (γ-PGA) powder was usually used as hemostatic agent because of its excellent physical properties of water-absorption and water-locking. However, if γ-PGA absorbs enough water, how about its blood compatibility? Here, the other side of the coin was investigated. The anticoagulant properties of γ-PGA were characterized by in vitro coagulation tests, hemolytic assay, platelet adhesion, and platelet activation. Moreover, cytotoxicity experiments of γ-PGA were also carried out by MTT assay. Results indicated that the sufficient water-absorbed γ-PGA has good anticoagulant property and non-cytotoxicity. It means γ-PGA has good anticoagulant property, non-cytotoxicity. If γ-PGA has absorbed enough water, it can be used as an anticoagulation biomaterial. With double effects (coagulation and anticoagulation), the γ-PGA with desirable bioproperties can be readily tailored to cater to various biomedical applications.
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PubMed
高影响因子
Molecular Catalysis
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2020
·
IF 3.687
Ning Xiang,Xiaojin Han,Yarong Bai,Qiaoyan Li,Jianfeng Zheng,Yulin Li,Yaqin Hou,Zhanggen Huang
Supported noble metal catalysts have been widely utilized for HCHO catalytic oxidation. When the active components are fixed, the altering and regulation of the supports would have a huge effect on catalytic performance. Here, two types of Pd/γ-Al 2 O 3 catalysts with different support size (micro-γ-Al 2 O 3 and nano-γ-Al 2 O 3 , respectively) were fabricated and used for HCHO oxidation. Compared with the micro-sized counterpart, the Pd/nano-γ-Al 2 O 3 catalyst exhibited much superior HCHO oxidation performance which could totally oxidize 160 ppm of HCHO into harmless CO 2 under a WHSV of 100,000 mL g cat −1 h −1 at room temperature. Multiple characterizations including XRD, BET, TEM, CO chemisorption, FT-IR, O 2 -TPD, XPS and in situ DRIFTS were implemented to study the effect of γ-Al 2 O 3 support size on physicochemical properties of Pd/γ-Al 2 O 3 catalysts and elucidate the structure-activity relationship. The results revealed that large specific surface area, rich surface OH groups as well as high curvature of nano-γ-Al 2 O 3 not only facilitated HCHO adsorption, but also stabilized highly dispersed Pd species which then promoted the activation of oxygen and boosted formate species decomposition, and consequently leading to the enhanced HCHO oxidation performance of Pd/nano-γ-Al 2 O 3 . This work deepens the comprehension of support size-dependent activity of Pd/γ-Al 2 O 3 catalysts for HCHO oxidation and provides an alternative method to prepare high-performance Pd catalysts for HCHO oxidation.
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RSC Advances
·
2014
·Vol. 4
·期 18
·9314-9320
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IF 3.708
Xiangui Ding,Liu Bao,Jiang Jiang,Hongwei Gu
A facile method of synthesizing γ-Fe2O3 ultrathin nanoplates has been developed. These nanoplates are single crystalline and superparamagnetic at room temperature, with a thickness of only 1.4 nm. FTIR analysis has shown that the coordination mode between Fe and carboxyl group is dominated by bidentate configuration in the as prepared iron oleate complex, which is the key for producing the nanoplate morphology. By changing the reaction temperatures, the lateral size and thickness of nanoplates can be varied.
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高影响因子
MACROMOLECULAR CHEMISTRY AND PHYSICS
·
2022
·Vol. 223
·期 4
·2100416
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IF 2.996
Muhua Yuan,Haijun Wang,Huihui Li,Chunlei Yuan,Tong Wang,Haibo Yang
Adding additives is the most convenient and effective way to induce polar poly(vinylidene fluoride) (PVDF) crystals which exhibit excellent ferroelectronic, piezoelectric, and dielectric properties. In this work, a kind of environmentally friendly additive, deep eutectic solvent (DES), is introduced to induce the crystallization of polar phases and accelerate the α -to- γ phase transition, which enables the fraction of γ ( γ ′)-phase crystals to exceed 90% in the PVDF/DES composite containing only 1 wt% DES. The ion–dipole interaction between PVDF and hydrogen bond acceptor in DES induces the polar molecular conformation, thus bringing about the formation of polar phase crystals. However, hydrogen bond donor promotes the dispersion of hydrogen bond acceptor in PVDF matrix, contributing to the flexibility of the composites.
研究领域:
材料科学
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高分子化学
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RSC Advances
·
2015
·Vol. 5
·期 127
·104884-104890
·
IF 3.84
Yuan Cai,Huihui Huang,Lei Wang,Xiaojun Zhang,Yuewei Yuan,Rui Li,Hui Wan,Guofeng Guan
Mesoporous γ-AlOOH and γ-Al2O3 with fibrous morphology were successfully synthesized by an ionic liquid ([OMim]Br) assisted low temperature precipitation method using aluminum nitrate and ammonia as aluminum source and precipitant, respectively. The samples were characterized by XRD, TG, FT-IR, TEM, and N2 adsorption–desorption technique. The results showed that the concentration of [OMim]Br had a significant effect on the phase, porous structure, and morphology of γ-Al2O3 due to the strong interactions between [OMim]Br and γ-AlOOH. High purity γ-AlOOH was synthesized at 0.2 M [OMim]Br and γ-Al2O3 with a specific surface area of 243.53 m2 g−1, pore volume of 0.68 cm3 g−1, and average pore size of 11.10 nm was obtained after calcination. Furthermore, the recyclability of [OMim]Br was investigated. The recovery rate of [OMim]Br could reach 95.0 wt%, and the recycled [OMim]Br still had effects on the synthesis of γ-AlOOH and γ-Al2O3.
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STARCH-STARKE
·
2020
·
IF 2.226
Xue-Li Liu,Kun Zhang,Yu Hu,Zhengjuan Zhang,Jun Chen,TianLin Ma,JiaJia Wang
A new class of hydroxypropyl starch, γ-hydroxypropyl starch (γ-HPS), is synthesized by using 3-chloropropanol as the etherifying reagent. Two independent procedures for the determination of the number of moles of alkylene oxide combined per anhydroglucose unit (molar substitution, MS) in γ-HPS are described. The feasibility of the Zeisel-gas chromatographic technique and colorimetric determination are testified, and especially in the second approach, the stability and accuracy of dehydration process are also investigated. The concentrated sulfuric acid dehydration oxidation is replaced with 2-iodoxybenzoic acid oxidation while retaining the same acid degradation and the same ninhydrin color reaction. Furthermore, the reliability and the range of application of the methods are tested by analyzing three samples of γ-HPS and unmodified starch derivatives, and the results indicate that values of MS are in good agreement with each testing method.
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Catalysis Science & Technology
·
2016
·Vol. 7
·期 2
·466-480
·
IF 5.287
Sijia Liu,Xin Liang,Jie Zhang,Biaohua Chen
Two different kinds of γ-Al2O3 precursors: stick-like ammonium aluminum carbonate hydroxide and willow leaf-like boehmite could be selectively synthesized via a facile hydrothermal method by just adjusting reaction temperature. After heat treatment, γ-Al2O3 with two different morphologies (stick-like and willow leaf-like) were synthesized and used as supports for CoMo hydrodesulfurization catalysts. Fourier transform infrared spectroscopy of pyridine adsorption and NH3-temperature-programmed desorption showed that stick-like γ-Al2O3 (ACH) and willow leaf-like γ-Al2O3 (AOH) exhibited a lower Lewis acidity than commercial γ-Al2O3. X-ray diffraction indicated that CoMo oxidic catalysts supported on ACH and AOH contained more β-CoMoO4 phase. X-ray photoelectron spectroscopy and high resolution transmission electron microscopy revealed that after presulfurization, more CoMoS active sites and multilayered (Co)MoS2 slabs formed on ACH and AOH supports, thereby creating catalysts with a higher hydrodesulfurization activity in the hydrodesulfurization of thiophene and 4,6-dimethyldibenzothiophene.
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Materials Science & Engineering C-Materials for Biological Applications
·
2019
·
IF 4.959
Jin Feng,Qingshan Shi,Yulian Li,Jianfei Huang,Ruimin Li,Xiulin Shu,Wenru Li,Xiaobao Xie
Nanocomposites composed of Ag and γ-Fe 2 O 3 nanoparticles within poly-γ-glutamic acid (γ-PGA) derived amorphous carbon nitride (a-CN) films (Ag + γ-Fe 2 O 3 @a-CN) were synthesized by a one-step facile pyrolysis strategy. Transmission electron microscopy analysis shows that Ag and γ-Fe 2 O 3 nanoparticles were obtained in situ and homogeneously dispersed on the a-CN matrix. The average size of nanoparticles was 8.1 nm. The presence of γ-Fe 2 O 3 , Ag, and a-CN in the nanocomposite was confirmed by X-ray diffraction analysis, UV–visible absorption spectroscopy, Raman spectroscopy, and X-ray photoelectron spectroscopy. Ag + γ-Fe 2 O 3 @a-CN catalyzed the degradation of methyl orange. This catalyst was also recycled ten times by magnetic separation without any loss in efficiency. Ag + γ-Fe 2 O 3 @a-CN exhibited strong antibacterial activity against E . coli and S . aureus . It also exhibited excellent antibacterial activity even after 20 times magnetic recycling. This indicates that this is a promising recyclable antibacterial and catalyst for environmental applications.
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PubMed
高影响因子
JOURNAL OF COLLOID AND INTERFACE SCIENCE
·
2025
·
IF 9.7
Lina Ding,Jing Gong,Qihang Ding,Zhenyu Ma,Jia Liu,Chunyan Li,Xinming Gu,Manlin Qi,Biao Dong,Lin Wang
Developing intelligent theranostic strategies capable of real-time infection assessment and adaptive treatment remains a significant challenge in wound management. Here, we present a smart theranostic nanoplatform (Apt-Ag + -GNR) that integrates fluorescence-guided detection, real-time adaptive silver ion (Ag + ) release, and photothermal therapy (PTT) for the precise treatment of infections. This system utilizes interferon-γ (IFN-γ), an inflammation-specific biomarker with high detection sensitivity (limit of detection: 26.7 pg mL −1 ) as both a diagnostic indicator and a therapeutic trigger. Upon recognition of IFN-γ, the platform employs fluorescence resonance energy transfer -based detection to assess severity in real time. Concurrently, Ag + is dynamically modulated in response to IFN-γ levels, enabling severity-specific treatment. For mild infections, characterized by low fluorescence intensity and low IFN-γ expression, the system releases limited Ag + to eliminate bacteria while minimizing unnecessary intervention. For severe wound infection, characterized by high fluorescence signals and high IFN-γ levels, the platform combines Ag + therapy with PTT to enhance bacterial eradication. In vivo studies confirm that Apt-Ag + -GNR enables precise therapeutic modulation, effectively preventing overtreatment-related tissue damage, accelerating wound healing, and reducing inflammation. Histological and immunofluorescence analyses further demonstrate improved tissue regeneration. This platform has established a broadly applicable framework for adaptive theranostic systems, offering translational potential in managing severe wound infection models and providing a basis for future applications in chronic ulcers, diabetic wounds, and implant-related infections.
研究领域:
纳米医学
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感染性疾病治疗
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生物医学工程
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伤口愈合
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诊疗一体化
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Metabolites
·
2026
·Vol. 16
·期 9
·621
·
IF 4.5
Xin Tao,Shangbo Yan,Ranran Chen,Fangfang Ren,Hongjie Yang,Wenheng Long,Nan Gao
Background:γ-Valerolactone (GVL), a green volatile platform compound derived from lignocellulosic biomass, has recently been identified as one volatile organic compound produced by the plant growth-promoting rhizobacteriumStutzerimonas stutzeriNRCB010. Although our previous transcriptomic and phenotypic studies have verified that exogenous GVL can promote the growth of tomato seedlings, the global metabolic reprogramming behind this promoting effect remains unclear.Methods:Tomato seedlings were subjected to exogenous GVL treatments at three concentrations (0, 0.25, 0.5 g/L) for 24 h and 48 h separately. Combined with physiological growth measurements, ultra-high-performance liquid chromatography–tandem mass spectrometry-based widely targeted metabolomics was applied to systematically characterize GVL-mediated metabolic reprogramming.Results:GVL remarkably improved seedling height, biomass and root development, with 0.25 g/L GVL showing the strongest promoting effect. A total of 703 metabolites including lipids, flavonoids and alkaloids were identified. Principal component analysis and orthogonal partial least squares discriminant analysis revealed distinct metabolic separation between control and treated groups, verifying time and concentration dependent metabolic shifts. After 24 h, GVL activated primary pathways (the tricarboxylic acid cycle, amino acid and purine metabolism) to supply growth energy; after 48 h, central carbon and secondary biosynthetic pathways were enriched, and 0.5 g/L GVL specifically triggered defensive isoquinoline and indole alkaloid biosynthesis.Conclusions:GVL coordinately remodels primary and secondary metabolic networks to accelerate tomato seedling growth, which provides sufficient metabolomic evidence for developing GVL as a novel bio-based plant biostimulant.
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Materials Science and Engineering B-Advanced Functional Solid-State Materials
·
2026
·
IF 5.7
Lixin Qiu,Tingting Yan,Dongyang Xi,Kai Wang,Yang Liu,Lan Jin
In this work, pure cubic-phase γ-NH 4 Ho 3 F 10 nanocrystals were successfully synthesized via a facile one-step hydrothermal method. X-ray diffraction (XRD), scanning electron microscopy (SEM) and transmission electron microscopy (TEM) were employed to conduct detailed characterizations of the crystal structure, morphology and size of the as-prepared samples. The fluorescence emission properties of γ-NH 4 Ho 3 F 10 nanocrystals under atmospheric pressure were tested by a fluorescence spectrometer. The as-prepared samples appear white under natural light and exhibit a pink-purple color upon excitation with a 365 nm ultraviolet light. The luminescence lifetime and quantum efficiency of the sample were measured. Under 370 nm excitation, the average lifetime of the sample was approximately 6.6 μs, with a quantum efficiency of 10.17%. Furthermore, high-pressure fluorescence experiments were carried out on the samples with the excitation source fixed at 638 nm. It was found that no changes occurred in the high-pressure fluorescence transitions, from which it is inferred that the γ-NH 4 Ho 3 F 10 nanocrystals maintain structural stability under 12.9 GPa. Therefore, it exhibits promising application potential in fields such as high-pressure sensing and is expected to achieve pressure detection under extreme conditions.
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FOOD SCIENCE AND TECHNOLOGY RESEARCH
·
2021
·
IF 0.668
Yunbo Li,Benguo Liu,Mengmeng Yu,Sheng Geng
Cyclodextrins (CDs) are widely applied to improve the aqueous solubility and stability of nutraceuticals with the advantages of high safety and low cost. In this study, the binding capacities of CDs (α-CD, β-CD, maltosyl-β-CD, hydroxypropyl-β-CD and γ-CD) with mangiferin were compared by the phase solubility method and isothermal titration calorimetry. γ-CD could completely encapsulate mangiferin at the molar ratio of 1:1, which coincided with the molecular docking and ONIOM calculation results that γ-CD had the lowest interaction energy with mangiferin. The independent gradient model (IGM) visualized the intermolecular non-covalent binding and electrostatic potential around mangiferin during interaction. By complexing with γ-CD, mangiferin was molecularly dispersed in the matrix of γ-CD with its aromatic ring in the hydrophobic cavity. Compared with pure mangiferin, the mangiferin/γ-CD complex exhibited the stronger chemical antioxidant activities. The obtained result can promote the application of mangiferin and γ-CD in foods.
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危险品化学品经营许可证（带存储）