COMPOSITE STRUCTURES
·
2024
·
IF 6.3
Yuchen Guo,Pengwan Chen,Rui Liu,ZhijianYang,Feng Zhang,Liyang Feng,Kezhen Lv,Bo Zhou,Gaoyang Hu
As the predominant component in polymer bonded explosives (PBX), explosive crystals is an important factor affecting the compressibility of PBX powder. To obtain the effects of crystal quality on the mechanical properties and meso -mechanical behavior of PBX powder during die pressing, the compaction density, Brazilian strength, as well as crack propagation and energy dissipation mechanisms were systematically studied based on experiments and Discrete Element Method (DEM) simulations. The experimental results revealed that, under identical pressure, PBX parts composed of 1,3,5,7-tetranitro-1,3,5,7-tetraazecycloctane (HMX) crystals with more internal defects and lower strength will exhibit higher density and Brazilian strength. The simulation results demonstrated that crystal fragmentation occurs throughout the pressing process. The increased Brazilian strength of PBX containing low quality crystals may be attributed to more defects and larger specific surface area of the crystals. Crystal fragmentation can effectively promote particle rearrangement, resulting in higher strain of the PBX powder. During the compression process, the lower the crystal quality, the greater their susceptibility to fracture and the reduced conversion of external work into elastic potential energy. Consequently, the increase in PBX size caused by the release of elastic potential energy after unloading is therefore minimized, resulting in improved compressibility of the PBX.
✓ 已验证
产品关联
DOI
高影响因子
Nature Communications
·
2025
·Vol. 16
·期 1
·1-10
·
IF 15.7
Guo Jiaqi,Pei Songfeng,Huang Kun,Zhang Qing,Zhou Xizhong,Tong Jinmeng,Liu Zhibo,Cheng Hui-Ming,Ren Wencai
With the rapid development of graphene industry, low-cost sustainable synthesis of monolayer graphene oxide (GO) has become more and more important for many applications such as water desalination, thermal management, energy storage and functional composites. Compared to the conventional chemical oxidation methods, water electrolytic oxidation of graphite-intercalation-compound (GIC) shows significant advantages in environmental-friendliness, safety and efficiency, but suffers from non-uniform oxidation, typically ~50 wt.% yield with ~50% monolayers. Here, we show that water-induced deintercalation of GIC is responsible for the non-uniform oxidation of the water electrolytic oxidation method. Using in-situ experiments, the control principles of water diffusion governing electrochemical oxidation and deintercalation of GIC are revealed. Based on these principles, a liquid membrane electrolysis method was developed to precisely control the water diffusion to achieve a dynamic equilibrium between oxidation and deintercalation, enabling industrial sustainable synthesis of uniform monolayer GO with a high yield (~180 wt.%) and a very low cost (~1/7 of Hummers’ methods). Moreover, this method allows precise control on the structure of GO and the synthesis of GO by using pure water. This work provides new insights into the role of water in electrochemical reaction of graphite and paves the way for the industrial applications of GO.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
LWT-FOOD SCIENCE AND TECHNOLOGY
·
2024
·
IF 6
Ning Wang,Donghua Wang,Dandan Wu,Liqi Wang,Xiuqing Zhu,Dianyu Yu
In this study, Janus nanoparticles were prepared and used to construct Pickering emulsion as an emulsifier in presence of lipase. The results showed that Janus nanoparticles could be used to stable water phase in emulsion and the average particle size of emulsion was 60 μm. Phytosterol ester was successfully synthesized in Pickering emulsion catalytic system by using oleic acid as acyl accepter, and the phytosterol conversion reached 91.65 ± 2.07% under the following conditions: emulsifier amount of 1.0 wt%, oil-water ratio of 6:1, phytosterol concentration of 110 mmol/L, lipase dosage of 20 g/L, reaction temperature of 45 °C. Compared with biphasic catalytic system, Pickering emulsion catalytic system could enhance the catalytic efficiency and shorten the reaction time due to large interface area and short molecule diffusion distance. At the end of reaction, Janus nanoparticles could be recovered by simple centrifugation, the relative activity of lipase remained 72.89 ± 1.83% after repeated use for 6 times. Overall, this paper provides a novel and high efficiency interfacial biocatalysis technique for the synthesis of phytosteryl oleate.
✓ 已验证
产品关联
DOI
高影响因子
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2024
·
IF 7.7
Yafei Zhang,Xiaojing Tian,Kai Zhang,Kaixuan Zhao,Yang Wang,Chenwei Ma,Jingjing Guo,Wenhang Wang
Although iron in meat is an important trace element for human diet, its presence also induces postprandial oxidative stress and aggravates the condition of patients with iron overload. To overcome this situation, a type of new tunable Fe-absorption bioactive materials was constructed in this study. First, four phenolic acids (Caffeic acid, Gallic acid, Protocatechuic acid, Chlorogenic acid) were grafted onto chitosan. Then, the copolymers were prepared into micron-level microspheres by emulsification method, which were characterized in adsorption isotherms (Langmuir model), swelling behavior and digestion characteristics. In order to verify the practical application effect of microspheres, Protocatechuic acid grafted chitosan microspheres as the representative were used in sirloin powder to observe their effects in vitro digestion and rat experiment. In the present study, microspheres were innovatively applied in meat consumption, which significantly inhibited the oxidation of meat in the process of digestion and effectively controlled the iron absorption. These results are expected to play an important role in promoting the healthy consumption of meat around the world, improving gastrointestinal redox status through dietary assistance, and treating diseases related to iron overload.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Comparative Biochemistry and Physiology D-Genomics & Proteomics
·
2024
·
IF 2.2
Shengli Fu,Kun Qian,Xiao Tu,Jie Lu,Tuo Yao,Lingtong Ye,Jianmin Ye
The structure of fish intestines does not have a clear regional division, while the function of the intestines may be related to their structure. Therefore, in this study, the delimitation of intestinal segments in pufferfish ( Takifugu obscurus ) was achieved by morphological analysis. Subsequently, enzyme activity, intestinal microbiota, and gene expression were examined to compare the differences among the pufferfish various segments. According to four morphological parameters: height of mucosa folds (HF), width of mucosa folds (WF), thickness of muscularis (TM), and cross-sectional area (CSA), the pufferfish's intestine was divided into anterior intestine (AI), middle intestine (MI), and posterior intestine (PI). The activity levels of amylase, lipase, and trypsin in the AI and MI were significantly higher than these in the PI. According to the analysis of 16S rDNA, the dominant microbiota at the phylum level in the different segments were Epsilonbacteraeota, Spirochaetes, and Proteobacteria. At the genus level, there were variations observed in the relative abundance of Brevinema, Mycobacterium, Bradyrhizobium, and Microvirga. α diversity analysis revealed that the richness indexes (Ace and Chao1) were the lowest in the MI, while β diversity analysis revealed significant difference in intestinal microbial community composition among the three intestinal segments. Furthermore, RNA-Seq was used to identify differential expression genes (DEGs) and biological pathways among the different intestinal segments. The DEGs between the AI and MI were enriched in pancreatic secretion and protein digestion and absorption, those between AI and PI were involved in ascorbate and aldarate metabolism and glutathione metabolism, and those between MI and PI were involved in steroid biosynthesis, fat digestion and absorption, vitamin digestion and absorption, and glycine, serine and threonine metabolism. In conclusion, the presented results compare and analyze the differences in various intestinal segments of pufferfish, which will be conductive to future exploration of the functions of these different segments.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
COMPOSITES SCIENCE AND TECHNOLOGY
·
2024
·
IF 8.3
Jingjing Zhang,Jialin Zhang,Daoqing Liu,Jianhui Zeng,Zhenqiang Ye,Meng Han,Shuye Zhang,Yimin Yao,Rong Sun
With the increased integration of electronic devices, effective heat management becomes imperative. Thermally conductive phase change composites play a vital role by efficiently conducting heat and utilizing matrix phase change for heat storage. Conventional materials encounter difficulties such as low thermal conductivity, restricted heat storage density, and vulnerability to leakage. This study presents a novel method combining electrospinning and ice-templating method to produce aerogel microspheres with sea urchin-like structures, resolving mentioned issues. The microspheres exhibit a radial microstructure and controllable size, serving as efficient fillers for the easy production of high-performance phase change materials. The microspheres are able to create an efficient interlocking mechanism with surface spike structures, forming a continuous thermal conduction and spatially confined network in the composite material. At a filler content of 43.9 vol%, the thermal conductivity of the Al aerogel microsphere/paraffin composite reaches a peak value of 3.2 W/mK, accompanied by a contact thermal resistance of 1.2 × 10 −6 Km 2 /W. Subjecting the composite to elevated temperatures well above the matrix's phase change temperature preserves its structural stability. This work reports a new structured filler moulding method that supports the development of high performance thermally conductive phase change composites.
✓ 已验证
产品关联
DOI
高影响因子
PROGRESS IN ORGANIC COATINGS
·
2024
·
IF 6.5
Lei Xia,Tianyi Lu,Miqiu Kong,Jingke Pei,Yajiang Huang,Yanhua Niu,Yadong Lv,Guangxian Li
Despite extensive research on the impact of environmental weathering on the degradation of electromagnetic wave absorbing (EWA) coatings, the influence of material composition on their service stability remains underexplored. In this study, we prepared EWA coatings with epoxy resin as the matrix and flaky carbonyl iron (FCI) as the absorber, at concentrations of 50 wt%, 60 wt%, and 70 wt%. These coatings underwent a 192-h combined UV irradiation-salt spray accelerated aging test to examine the effects of varying absorber concentrations on their corrosion behavior and mechanisms. Surface morphology, chemical structure evolution, and corrosion diffusion were analyzed using X-ray diffraction (XRD) and field emission scanning electron microscopy (FE-SEM) with energy-dispersive X-ray spectroscopy (EDX). Corrosion behaviors and their impact on wave absorption performance were further investigated using electrochemical impedance spectroscopy (EIS) and electromagnetic simulations. Our results show that increasing FCI content accelerates the corrosion rate of the composite coating. This acceleration is attributed to the reduced protective effect of the epoxy matrix at higher FCI concentrations and the defects caused by FCI corrosion, which facilitate the penetration of corrosive media. This study elucidates the influence of varying absorber concentrations on the weather resistance of the coatings and their microscopic mechanisms, providing valuable insights for optimizing the service stability of EWA coatings.
✓ 已验证
产品关联
DOI
高影响因子
Nature Communications
·
2024
·Vol. 15
·期 1
·1-16
·
IF 14.7
Zhang Ruotong,Zhang Chengzhi,Fan Xiaoxue,Au Yeung Christina C. K.,Li Huiyanchen,Lin Haisong,Shum Ho Cheung
Robotics for scientific research are evolving from grasping macro-scale solid materials to directly actuating micro-scale liquid samples. However, current liquid actuation mechanisms often restrict operable liquid types or compromise the activity of biochemical samples by introducing interfering mediums. Here, we propose a robotic liquid handling system enabled by a novel droplet actuation mechanism, termed electret-induced polarization on droplet (EPD). EPD enables all-liquid actuation in principle and experimentally exhibits generality for actuating various inorganic/organic liquids with relative permittivity ranging from 2.25 to 84.2 and volume from 500 nL to 1 mL. Moreover, EPD is capable of actuating various biochemical samples without compromising their activities, including various body fluids, living cells, and proteins. A robotic system is also coupled with the EPD mechanism to enable full automation. EPD’s high adaptability with liquid types and biochemical samples thus promotes the automation of liquid-based scientific experiments across multiple disciplines.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF MATERIALS SCIENCE & TECHNOLOGY
·
2025
·
IF 14.3
Miao Li,Yu Zhang,Zihao Chen,Yewei Zhang,Bin Yang,Yuan Liu,Tao Zhang,Xiaoxiao Huang
Logical material compositions and ingenious microstructure designs are being embraced as auspicious methods for achieving high-performance electromagnetic wave (EMW) absorbers. Herein, we developed boron and nitrogen co-doped nanotubes using a homogeneous precursor pyrolysis method, with the integration of magnetic Co nanoparticles uniformly dispersed onto the nanotubes. The one-dimensional nanotube microstructure remarkably mitigates the issues associated with magnetic nanoparticle aggregation, thereby enhancing the EMW transport path. Furthermore, the low dielectric constant of the BCN effectively mitigates impedance mismatch. Consequently, upon optimizing the one-dimensional Co@BCN nanotubes, remarkable EMW absorption performance is demonstrated at a filling ratio of 10 wt.%, with an effective absorption bandwidth of 5.33 GHz (1.8 mm) and a minimum reflection loss of −69.3 dB (2.2 mm). Experimental findings and radar cross-section simulations underscore the excellent EMW absorption properties of the prepared one-dimensional Co@BCN nanotubes, culminating in this simple co-doping synthesis strategy serving as a novel approach for fabricating high-performance EMW absorbers.
✓ 已验证
产品关联
DOI
高影响因子
MOLECULAR MEDICINE
·
2024
·Vol. 30
·期 1
·1-16
·
IF 6
Zhang Yanbin,Bai Jing,Xiao Bin,Li Chunyan
Osteoporosis is characterized by reduced bone mass due to imbalanced bone metabolism. Exosomes derived from bone mesenchymal stem cells (BMSCs) have been shown to play roles in various diseases. This study aimed to clarify the regulatory function and molecular mechanism of BMSCs-derived exosomes in osteogenic differentiation and their potential therapeutic effects on osteoporosis. Exosomes were extracted from BMSCs. Bone marrow-derived macrophages (BMDMs) were cultured and internalized with BMSCs-derived exosomes. Real-time quantitative PCR was used to detect the expression of macrophage surface markers and tripartite motif (TRIM) family genes. BMDMs were co-cultured with human osteoblasts to assess osteogenic differentiation. Western blot was performed to analyze the ubiquitination of triggering receptor expressed on myeloid cell 1 (TREM1) mediated by TRIM25. An ovariectomized mice model was established to evaluate the role of TRIM25 and exosomes in osteoporosis. Exosomes were successfully isolated from BMSCs. BMSCs-derived exosomes upregulated TRIM25 expression, promoting M2 macrophage polarization and osteogenic differentiation. TRIM25 facilitated the ubiquitination and degradation of TREM1. Overexpression of TREM1 reversed the enhanced M2 macrophage polarization and osteogenic differentiation caused by TRIM25 overexpression. TRIM25 enhanced the protective effect of BMSCs-derived exosomes against bone loss in mice. These findings suggested that BMSCs-derived exosomes promoted osteogenic differentiation by regulating M2 macrophage polarization through TRIM25-mediated ubiquitination and degradation of TREM1. This mechanism might provide a novel approach for treating osteoporosis.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
LANGMUIR
·
2024
·
IF 3.7
Qiang Wang,Zhihao Shen,Qiuxia Wang,Chuanqi Li,Haidong Jia,Han Sun,Pingan Pei,Chang Shan,Liangyu Wu,Yifan Luo,Han Jia,Pan Huang
Great aqueous dispersibility, a large specific surface area, and high impermeability make graphene oxide (GO) the ideal candidate for a high-performance corrosion inhibitor. Numerous symmetrical modification methods have been reported to enhance the adsorption of GO on metal surfaces in various corrosive media. This work aims to investigate the enhancement and mechanism of unilateral hydrophobic modification on the corrosion inhibition performance of GO. In this study, amphiphilic Janus GO (JGO) was prepared by grafting hydrophobic alkyl chains on one side of GO, and its anticorrosion performance was evaluated via weight loss experiments and electrochemical tests. The results revealed that the corrosion inhibition efficiency for Q235 mild steel (MS) in a 1 M HCl aqueous solution of 25 ppm JGO (81.08%) was much higher than that of GO at the same concentration (22.12%). Furthermore, the Langmuir adsorption isotherm and computational study demonstrated that the synergistic effect of physical adsorption and chemical adsorption promoted the hydrophilic side of JGO close to the surface of the metal, and the dense protective layer was formed by the hydrophobic chains toward the corrosive medium, which effectively hindered the corrosion of MS by the acidic liquid. This study emphasizes the significant role of asymmetrically modified hydrophobic alkyl chains in improving the corrosion prevention performance of GO and provides a perspective for the structural design of GO-based corrosion inhibitors.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Materials Today Bio
·
2025
·
IF 10.2
Chenhui Chen,Yuqi Xie,Qinfeiyang Zhang,Junyan Cao,Jixing Lin,Xian Tong,Yihao Wu,Li Zhu,Peng Gao,Jianfeng Ma
Bacteria are pivotal in the etiology of dental caries, underscoring the critical importance of effective plaque control in mitigating dental tissue diseases. Superhydrophobic materials, with their exceptional properties of non-wettability, antibacterial activity, and self-cleaning capabilities, present a promising approach for caries prevention. However, their clinical application remains constrained by challenges in achieving stable adhesion to tooth surfaces. Inspired by the natural adhesion mechanisms of acquired salivary pellicle (ASP), we synthesized Janus amphiphilic superhydrophobic nanoparticles comprising 1H,1H,2H,2H-perfluorooctyltriethoxysilane (FOTS), nano-silica, and the enamel binding peptide DDDEEKC-Peg(2000)-COOH. These nanoparticles were engineered to form a superhydrophobic film (FOTS-SiO 2 -Peptide) on tooth surfaces. Experimental analyses revealed rapid adsorption of these nanoparticles onto enamel, with their exposed surfaces creating a durable superhydrophobic layer that remained stable under diverse thermal conditions. Topical application of FOTS-SiO 2 -Peptide significantly reduced the incidence and severity of dental caries while preserving oral microbiota diversity and avoiding adverse effects on surrounding mucosal tissues. Safety and efficacy evaluations confirmed the biocompatibility of these Janus nanoparticles, highlighting their potential as a novel biomedical solution for caries prevention.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）