INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH
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2026
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IF 3.9
Yifan Yue,Baohe Wang,Aiping Wang,Fuying Zhao,Jing Zhu,Jing Ma
The catalytic efficiency for methyl methacrylate (MMA) production via aldol condensation of methyl propionate (MP) and formaldehyde (FA) depends on the acid–base and structural properties of the catalyst. Inspired by this, a synergistic design strategy is implemented by fabricating Cs/Al-MCM-41 catalysts, where Al doping preserves ordered mesopores and tunes acid–base properties. This approach generates an optimal density of medium acid sites together with a balanced distribution of weak-to-medium base sites, leading to 90% MMA selectivity and a space-time yield of 0.29 g/(gcat·h). Moreover, the mesoporous confinement not only enhances the dispersion of Cs active species but also suppresses the condensation of coke precursors, thereby significantly improving the catalyst stability. Density functional theory (DFT) calculations reveal that basic Cs–O–Si sites and acidic Al sites cooperatively activate MP and FA, promoting aldol condensation. This work demonstrates that the integration of targeted acid–base regulation with structural confinement provides a rational catalyst design principle for efficient aldol condensation.
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SENSORS AND ACTUATORS A-PHYSICAL
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2026
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IF 5.1
Zhibo Zhou,Yunqing Gu,Yun Ren,Zhou Li,Denghao Wu,Zhenxing Wu,Chengqi Mou
P(NIPAM-AM)/CS/TA-Fe 3+ hydrogel integrates NIR actuation and self-sensing. • Optimized network enables a 4.7 s fast response and 104° maximum bending. • TA-Fe 3+ coordination offers a high photothermal conversion efficiency of 27.76%. • Linear resistance-strain mapping predicts bending angles with ≤ 2.67% error. • The dual-function material allows real-time feedback for closed-loop control. Conventional hydrogel actuators often suffer from single functionality and a lack of real-time state feedback, restricting their potential in closed-loop control and intelligent applications. To address this, we designed a synergistically crosslinked composite hydrogel based on poly(N-isopropylacrylamide-co-acrylamide) (P(NIPAM-AM)), tannic acid-iron ion (TA-Fe 3+ ) complexes, and chitosan (CS). This hydrogel integrates near‑infrared (NIR)‑driven actuation with resistive self‑sensing and exhibits excellent shape programming and multidirectional actuation capabilities. By systematically optimizing the composition, the hydrogel with 0.1 mL of CS solution achieves a rapid response time of only 4.7 s and a maximum bending angle of 104°. Furthermore, at an Fe 3+ content of 120 mg, the hydrogel demonstrates a high photothermal conversion efficiency of 27.76% and an initial conductivity of 2.549 (Ω·m) −1 . It exhibits excellent self-sensing characteristics, with a bending gauge factor of 0.019 and high angle-sensing accuracy with an error of ≤ 2.67%. This work provides a simple and efficient strategy for developing intelligent soft materials that integrate actuation and sensing. Download: Download high-res image (220KB) Download: Download full-size image
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JOURNAL OF MATERIALS SCIENCE & TECHNOLOGY
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2026
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IF 16.8
Zhaoqi Zhang,Qian Ji,Hongfei Zhang,Heng Liu,Lei Zhao,Mengna Zhang,Lu Chen,Qian Li,Shaokang Guan
Poly(TA-Arg) coating with self-supplying NO fabricated via ethanol-water system. • Poly(TA-Arg) sample possesses a low degradation rate. • HA@CS nanoparticles synthesized with optimal HA:CS ratio. • HA@CS sample promotes endothelialization via PI3K-Akt-eNOS and Nrf2 pathways. Rapid degradation and inadequate re-endothelialization hinder the clinical application of biodegradable magnesium (Mg) alloy stents, while thrombosis and bacterial colonization further compromise early implant performance. To address these challenges, a hierarchical bilayer coating, consisting of an inner poly(α-thioctic acid)-L-arginine (Poly(TA-Arg)) layer and an outer hyaluronic acid/chitosan (HA@CS) nanoparticle layer (particle size, ∼240 nm), was fabricated on a fluorinated ZE21B Mg alloy. The Poly(TA-Arg) layer supported endothelial cell (EC)-mediated endogenous nitric oxide (NO) production. It also provided strong interfacial adhesion and corrosion protection, reducing the corrosion current density to 5.60 × 10 −8 A cm −2 . The HA@CS layer exhibited antioxidant activity, prolonged clotting time, low hemolysis, and > 99% antibacterial efficacy, as determined by plate counting. The bilayer coating promoted EC proliferation while inhibiting smooth muscle cell growth. RNA sequencing suggested that the pro-endothelialization effect was associated with PI3K-Akt- endothelial nitric oxide synthase-related signaling and an Nrf2-related antioxidant response. In a rat abdominal aorta model, the coated wire was surrounded by a thin, well-organized neointima with endothelial coverage, minimal inflammation, and no evident thrombosis. No obvious histopathological abnormalities were observed in major organs, and hematological parameters remained within normal ranges. This multifunctional coating provides a potential strategy for improving the vascular compatibility of biodegradable Mg stents. Download: Download high-res image (332KB) Download: Download full-size image
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Journal of Macromolecular Science Part B-Physics
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2026
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IF 1.7
Xinyi Wan,Mengmeng Xiong
Flexible wearable strain sensors that accurately capture joint motion are essential for rehabilitation assessment, motion monitoring, and human–machine interaction. However, conventional hydrogel sensors often suffer from limited mechanical robustness, poor durability, insufficient conductivity, or biocompatibility concerns caused by conductive fillers and chemical crosslinkers. Here, we report a multifunctional biocompatible hydrogel strain sensor, PCH, constructed from a polyvinyl alcohol/chitosan (PVA/CS) double-network matrix, hydroxyl ethylidene diphosphonic acid (HEDP)-mediated dynamic coordination crosslinking, and potassium chloride (KCl)-based ion conduction. FTIR analysis confirms the formation of a hybrid PVA/CS–HEDP network stabilized by hydrogen bonding and phosphonate-associated interactions, contributing to enhanced mechanical integrity. The PCH hydrogel exhibits favorable tensile properties, stable cyclic loading–unloading behavior, and reliable durability. Electromechanical tests show a linear and sensitive strain response with a gauge factor of 0.84 and high linearity (R2 = 0.9976). In joint mobility monitoring, PCH generates precise angle-dependent signals during ±90° wrist bending and maintains stable output under continuous bidirectional motion. It also shows repeatable finger-joint sensing performance and favorable cytocompatibility, hemocompatibility, and skin compatibility, demonstrating strong potential for real-time wearable joint monitoring.
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ENVIRONMENTAL RESEARCH
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2026
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IF 8.2
Qiawen Zhang,Wensheng Qi,Dapeng Liu,Ganwei Zhang,Shusu Shen,Yaoliang Hong
To improve the permeability-selectivity balance in polyamide nanofiltration membranes, a dual-charged composite membrane (PES-CS/SBE-β-CD-PA) was fabricated via interfacial polymerization on a self-assembled CS/SBE-β-CD interlayer designed to regulate the interfacial availability and transport of PEI monomers during polyamide formation, yielding a selective layer with a lower apparent cross-sectional thickness (approximately 173 nm) and more uniform morphology. The negative potential of the interlayer-terminated surface before IP (−9.8 mV), the positive potential of the final PA surface (15.63 mV), and the sequential fabrication process support the designed negative-interlayer/positive-PA configuration. The optimized membrane exhibits a molecular weight cut-off of 445 Da, an average pore size of 0.51 nm, and MgCl 2 and MgSO 4 rejections of 94.00% and 91.34%, respectively, while maintaining a water permeance of 15.20 L m −2 ·h −1 ·bar −1 . The morphology, pore-size, and charge results support a separation mechanism combining steric/hydration effects with charge-dependent Donnan partitioning. In addition, the membrane shows improved antifouling properties and stable separation performance during 72 h continuous filtration under the tested conditions. This work presents an effective interfacial-regulation strategy for constructing nanofiltration membranes with balanced separation and antifouling performance.
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Regenerative Biomaterials
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2026
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IF 8.1
Zhou Xiaosong,Wang Zongliang,Wang Yu,Guo Min,Zhang Peibiao
Repairing orbital bone defects remains a complex challenge in craniofacial surgery. Existing bone repair materials are plagued by issues such as intricate preparation processes and inadequate consideration of the spatiotemporal characteristics of bone healing. This study aimed to enhance the osteoinductive activity of poly (glycolide-co-caprolactone) (PGCL)-based materials through bicomponent modification, thereby providing a basis for the design of clinical bone repair materials. Hydroxyapatite/calcium sulfate/PGCL (HA/CS/PGCL) composite microspheres were fabricated via electrostatically assisted spray evaporation (ESASE). Their physicochemical properties and in vitro/in vivo osteogenic efficacy were evaluated using degradation-mineralization assays, MC3T3-E1 cell differentiation assessments and a rabbit orbital bone defect model. Innovatively, CS mesocrystal pore structure regulation was introduced to synergize with HA, achieving multidimensional optimization of surface hydrophilicity, sequential calcium ion release and mechanical properties. Results showed that in vitro mineralization formed native-like hydroxyapatite structures within 14 days. On HA/CS/PGCL surfaces, the proliferation activity of MC3T3-E1 cells reached 1.8 times that of the PGCL group after 7 days, with a 1.6-fold increase in alkaline phosphatase activity. In vivo, the composite microspheres achieved a new bone volume ratio (BV/TV) of 78.72% at 10 weeks, resulting in complete closure of the bone defect. Their trabecular structural parameters (trabecular thickness, Tb.Th; trabecular number, Tb.N) outperformed those of the single-component groups. Histological staining confirmed their ability to induce ordered collagen arrangement and the formation of dense new bone. In conclusion, the HA/CS synergistic modification strategy achieved the sequential release of calcium ions during bone repair and spatial regulation of the microsphere surface pore structure. The superior performance of HA/CS/PGCL microspheres in repairing complex bone defects lays an experimental foundation for clinical translation. Further research into the interactions between ion release and cell signaling is warranted.
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PROGRESS IN ORGANIC COATINGS
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2026
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IF 7.9
Pengyu Li,Xiaohua Feng,Mingsheng Wang,Xiangkui Liao,Yi Liu,Hua Li
This work proposes a generalizable structural strategy for designing microwave-absorbing coatings that are both thickness-tolerant and disturbance-resistant. Here, we develop a coating based on a porous PI wall-encapsulated filler structure, in which the unique pore-wall interfaces markedly smooth the thickness evolution of impedance matching and attenuation, enabling effective Ku -band absorption over a 2.5–3.1 mm thickness window. An appropriate composition ratio combined with PI-encapsulated porous structure collectively achieves thickness-insensitive strong absorption performance. To evaluate its anti-interference capability, short-term surface oxidative etching tests were performed. The results show that, even after surface erosion, the internal wall-encapsulated network preserves stable Ku -band absorption and radar-cross-section reduction, maintaining the thickness-insensitive characteristics.
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PLoS One
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2026
·Vol. 21
·期 7
·e0354590
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IF 2.8
Wenjing Zhao,Ying Liu,Jiali Yao,Zhenlu Zhou,Linlu Yan,Hao Liang,Qiping Hu
Injectable thermosensitive hydrogels have been widely investigated as minimally invasive scaffolds for three-dimensional (3D) cell culture. In this study, we systematically screened a chitosan (CS)/β-glycerophosphate (β-GP)/hydroxyethyl cellulose (HEC) ternary hydrogel system using a 2 × 2 × 2 factorial design. By evaluating gelation kinetics, injectability, and structural stability through a weighted scoring model, two superior formulations (G1 and G3) were selected for their ability to balance rapid gelation at 37 °C with reliable room-temperature injectability. Subsequent biological evaluations demonstrated that, compared to conventional 2D cultures, the 3D hydrogels supported robust cellular viability and spatial proliferation through Day 10. The stable biomimetic matrix provided essential physical anchorage, enabling Huh7 cells to self-assemble into dense tumor spheroids and BMSCs to establish spatial networks. This study presents a structured formulation-screening strategy and demonstrates the effectiveness of the CS/β-GP/HEC hydrogel as a reliable platform for in vitro 3D cell culture applications.
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FOOD CHEMISTRY
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2026
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IF 10.4
Yuying Gao,Zhiguo Xiong,Caiying Wu,Min Fan,Li Li
Chitosan (CS), a renewable natural polymer, facing constraints in its application within the food packaging field due to the low heat-sealing strength after film formation by the casting method. This study successfully developed a novel and environmentally friendly CS active composite film via hot-press method. Although oregano essential oil (OEO) slightly reduced tensile strength (TS), it improved elongation at break (EAB) (140% increase), heat-seal strength (18.5% increase), and potentiated antibacterial effects against E. coli and S. aureus compared with the CS-DES film. In the preservation of white bread, the CS-DES-OEO film effectively inhibited microbial growth, and the shelf life was extended by at least 4 days compared to conventional polyethylene (PE) packaging. This study verified the green characteristics of the choline chloride-based DES and OEO, addressed the inherent limitation of the low heat-seal strength of CS films, and further demonstrating the potential of CS-based active packaging in food preservation applications.
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Biomaterials Science
·
2025
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IF 5.7
Yun Tang,Jinghan Lin,Tingting Zhao,Lina Sun,Tingjiao Liu
Clinical trials have proven the beneficial effect of biodegradable orthopedic composites on bone repair; however, the mechanisms underlying composite-induced bone formation have not yet been fully explored. AZ91D magnesium alloy coated with carbon nanotubes (CNTs) and calcium phosphate (CaP)/chitosan (CS) (CNTs-CaP/CS-AZ91D) is a synthetic composite consisting of magnesium alloy, CNTs and CaP/CS. Its extracts induce the production of the calcitonin gene-related peptide (CGRP), a local neuropeptide that contributes to osteogenic differentiation, in dorsal root ganglion (DRG) neurons. This study was aimed at validating the upregulation of CGRP in CNTs-CaP/CS-AZ91D extract-induced DRG neurons. Besides, bone marrow-derived mesenchymal stem cells (BMSCs) showed greater osteogenic capacity after co-culture with CNTs-CaP/CS-AZ91D extract-induced DRG neurons, and this co-culture promoted autophagy in BMSCs to facilitate osteogenic differentiation. The dysregulation of CREB1/TRIM16/JAK1/STAT3 signaling was determined in BMSCs co-cultured with CNTs-CaP/CS-AZ91D extract-induced DRG neurons. However, all these results were counteracted by the knockdown of the CGRP receptor. In vivo study showed accelerated osteogenesis in the femur of CNTs-CaP/CS-AZ91D-implanted rats; however, this effect was inhibited by the CGRP receptor antagonist BIBN4096BS. In summary, this study highlights the critical role of the peripheral nervous system in osteogenesis and suggests the potential of CNTs-CaP/CS-AZ91D for improving bone formation in the future.
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COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
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2025
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IF 5.4
Dexu Liu,Keyu Liu,Huifu Chi,Shan Gao,Shuangqing Fu,Wei Li,Honglei Zhang
Poly(3-hydroxybutyrate) (PHB) has emerged as a promising biodegradable polymer with extensive potential for diverse applications. When modified with chitosan (CS), PHB demonstrates enhanced metal-loading capabilities, significantly expanding its utility in environmental fields. In this study, a green heterobimetallic gold (Au) and palladium (Pd) catalyst (designated as Au/Pd@PHB-CS), was synthesized through a sequential coordination reduction process on the surface of the PHB-CS nanosphere. The resulting bimetallic nanoparticles on the nanosphere predominantly exhibit a particle size of approximately 4.0 ± 0.9 nm and expose a substantial number of highly active crystal planes. Catalysts possess adsorption capacities for three pollutants: congo red (CR), methylene blue (MB) and 4-nitrophenol (4-NP). Besides, catalysts with low bimetallic loading of Au (0.11 wt%) and Pd (0.11 wt%) show significant removal efficiencies for the three pollutants. Notably, in the degradation of CR, the catalyst exhibits complete reduction of CR with exceptionally fast reaction kinetics. Furthermore, the catalyst maintains a high catalytic activity (95%) after multiple cycles of utilization. Compared to monometallic Au or Pd catalysts, bimetallic catalysts exhibit significantly enhanced reaction activity due to the synergistic interaction between the two metal components. This improved catalytic performance underscores the potential of PHB-based materials as effective catalyst supports, broadening their research and application prospects in catalysis.
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FOOD SCIENCE AND TECHNOLOGY INTERNATIONAL
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2023
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IF 2.3
Mingru Wang,Lei Ma,Peng Xie,Cuiping Li,Xiaoxi Yang,Yumiao Lang
The characterization and antioxidant ability of Res-loaded MP-CS stabilized Pickering emulsion, and its effects of fat reduction (25%, 50%, 75%, and 100%) in meat patties on pH, color, texture, cooking yield and antioxidant activity were investigated. Fat substitute using emulsion had no significant effect on pH and cooking yield. The addition of emulsion increased L* value and reduced a* value. a* value of meat patties with resveratrol added were higher than those without resveratrol group. Hardness and chewiness of meat patties with 25% and 100% fat replacement was lower than 50% and 75% fat replacement. The addition of emulsion could improve the network structure of meat patties and enhance oxidative stability. Oxidative stability of meat patties was improved by Res-loaded MP-CS stabilized Pickering emulsion. The results showed that MP-CS stabilized Pickering emulsion had great potential to be used as fat substitute for developing low-fat meat products, and the addition of resveratrol can improve the antioxidant ability of substitute fat meat products.
研究领域:
食品科学
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生物化学
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