MACROMOLECULES
·
2022
·
IF 6.057
Wenwen Zhao,Wenqiang Ma,Shuangping Xu,Xintian Wang,Hongge Jia,Jingyu Xu,Mingyu Zhang,Yanqing Qu,Jiao Liu
Oxygen/nitrogen (O2/N2) permselective membranes are widely used in both industrial and medical applications. Polysiloxane is one of the most important membrane materials with high oxygen permeability, but its poor capacities for gas separation and membrane formation limit its practical use. In this study, a soluble imide-bridged polypentamethyltrisiloxane (IBPPMS) with a high molecular weight (Mn = 8.91 × 104) was designed and synthesized via a hydrosilylation reaction between polypentamethyltrisiloxane (PPMS) and N,N′-bis(3-allyl)pyromellitic diimide (DAI) in NMP under Karstedt’s catalysis. The ladder-like structure of sample was analyzed and determined through infrared spectroscopy (IR), nuclear magnetic resonance spectroscopy (1H NMR and 29Si NMR), and gel permeation chromatography (GPC). The IBPPMS membrane displays excellent thermal resistance. Furthermore, its O2 permeation performance achieves 47.1 barrer, and its separation factor reaches 7.11 with a feeding proportion of 50% each for O2/N2, exceeding the 2008 Roberson upper bound. Thus, it appears that membranes can achieve high selectivity and permeability as well as exhibit desirable thermal properties and sufficient stability when separating numerous industrial significant gas mixtures. The discovery of trapezoidal structural backbone of this polymer materials substantially affects their separation properties and sustained performances.
研究领域:
材料科学
·
化学工程
✓ 已验证
产品关联
DOI
高影响因子
ELECTROCHIMICA ACTA
·
2017
·
IF 4.798
Jia Liu,Jinshuo Qiao,Hong Yuan,Jie Feng,Chao Sui,Zhenhua Wang,Wang Sun,Kening Sun
Ni modified Ce 0.6 Mn 0.3 Fe 0.1 O 2 (Ni-CMF) material is evaluated as an anode material for hybrid direct carbon fuel cell (HDCFC). The Temperature Programmed Reaction (TPR) and GC test results show that the Ni additive significantly promotes the oxidation of carbon and consequently accelerates the formation rate of CO. Moreover, the Ni-CMF material is found to show a high electrical conductivity compared to pure CMF in HDCFC operating conditions. Taking advantage of the excellent catalytic activity and high conductivity, the electrolyte-supported HDCFC with Ni-CMF anode shows a high maximum power density of 580.7 mW cm −2 at 800 °C, when activated carbon is used as the fuel. Furthermore, the cell displays good stability under galvanostatic operation at current density of 50 mA cm −2 at 750 °C. These results indicate that the designed Ni-CMF composite material has the potential to be developed as an alternative anode for HDCFCs.
研究领域:
材料科学
·
能源工程
✓ 已验证
产品关联
DOI
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2021
·
IF 13.273
Zepeng Rao,Guanhong Lu,Lu Chen,Asad Mahmood,Gansheng Shi,Zixia Tang,Xiaofeng Xie,Jing Sun
To identify the distinctive role of reactive oxygen species (ROS) and trace the intermediates not only help to decompose the pollutants in high efficiency but also for avoiding more harmful intermediates formed. Here, we developed a new method to generate different ROSs by controlling the atmosphere to distinguish their role in the degradation of flowing gas-phase VOCs, including o -xylene, styrene, and acetaldehyde. This method is in good agreement with the traditional sacrificial agent capture experiment. The results show that • OH radicals play a dominant role in the degradation of o -xylene and styrene, while • O 2 − radicals primarily take part in the acetaldehyde degradation. Additionally, we distinguish the role of holes, • OH and • O 2 − played during the VOCs photo-oxidation through the radical trapping, in situ DRIFTS, and GC-MS analysis. Under the attack of • O 2 − radicals, aromatic VOCs were photo-oxidized to intermediates containing benzene rings and ketones (i.e., toluene and butanone), while carbon chain compounds (i.e., 3-methylfuran and ethanol) tend to form under the action of • OH and holes. This can be associated with the different reaction paths initiated by ROS. For acetaldehyde removal, •O 2 − species facilitate the formation of acids (i.e., acetic acid) while the •OH species and holes lead to the production of ketones (i.e., acetone). This work provides deep understanding on the role of various ROS in the photocatalytic oxidation of VOCs, which can guide the design of efficient photocatalysts, selective formation of intermediates to be easily decomposed or as raw materials for further application.
研究领域:
环境科学
·
化学工程
✓ 已验证
产品关联
DOI
高影响因子
Nature Catalysis
·
2022
·Vol. 5
·期 1
·45-54
·
IF 40.706
Qi Guodong,Davies Thomas E.,Nasrallah Ali,Sainna Mala A.,Howe Alexander G. R.,Lewis Richard J.,Quesne Matthew,Catlow C. Richard A.,Willock David J.,He Qian,Bethell Donald,Howard Mark J.,Murrer Barry A.,Harrison Brian,Kiely Christopher J.,Zhao Xingling,Deng Feng,Xu Jun,Hutchings Graham J.
The oxidation of methane, the main component of natural gas, to selectively form oxygenated chemical feedstocks using molecular oxygen has been a long-standing grand challenge in catalysis. Here, using gold nanoparticles supported on the zeolite ZSM-5, we introduce a method to oxidize methane to methanol and acetic acid in water at temperatures between 120 and 240 °C using molecular oxygen in the absence of any added coreductant. Electron microscopy reveals that the catalyst does not contain gold atoms or clusters, but rather gold nanoparticles are the active component, while a mechanism involving surface adsorbed species is proposed in which methanol and acetic acid are formed via parallel pathways.
研究领域:
催化化学
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材料科学
·
环境科学
✓ 已验证
产品关联
DOI
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2022
·
IF 16.744
Peng Lin,Junpeng Shi,Liyan Ming,Yangyang Sheng,Liang Song,Maochun Hong,Yun Zhang
Hypoxia, which emerges in most solid tumors, significantly restricts therapeutic effect during treatment. To date, many smart nanoparticles that continuously generate O 2 have been developed to relieve hypoxia in tumors. Nevertheless, the short therapy duration resulting from the intrinsic properties of these nanoparticles left the subsequently generated O 2 not to be fully utilized, resulting in suboptimal treatment. Here, by loading mesopore MnO 2 (mMnO 2 ), photosensitizer and carbonic anhydrase IX inhibitor (CAI) on persistent luminescence nanoparticles (PLNPs), we designed an intelligent nanoplatform that can persistently exploit O 2 for efficient treatment of hypoxic tumors. In the tumor microenvironment, CAI is released rapidly as a result of degradation of mMnO 2 , reducing the intracellular pH value to accelerate the degradation process. This is not only advantageous for drug release and chemodynamic therapy (CDT) via released Mn 2+ , but is also beneficial for sustainably generating O 2 via composition of excessive H 2 O 2 to relieve hypoxia. With X-ray irradiation, the photosensitizer is activated by PLNPs, consuming generated O 2 to realize enhanced photodynamic therapy. Moreover, after cessation of X-ray irradiation, this process continues, achieving sustained and improved therapy for hypoxic tumors. By exploiting this method, we propose a new treatment methodology for hypoxic tumors.
研究领域:
肿瘤学
·
纳米医学
·
生物材料学
✓ 已验证
产品关联
DOI
高影响因子
Advanced Science
·
2022
·Vol. 9
·期 25
·2202591
·
IF 17.521
Pei Liu,Yangxue Fu,Fulong Wei,Teng Ma,Jingli Ren,Zhanjun Xie,Shanzheng Wang,Jinjin Zhu,Lianbin Zhang,Juan Tao,Jintao Zhu
Photodynamic therapy (PDT) is an emerging technique for treating tumors. Especially, topical administration of photosensitizers (PSs) is more favorable for superficial tumor treatments with low systematic phototoxicity. Yet, ineffective migration of PSs to targeted tumor tissues and rapid consumption of O 2 during PDT greatly limit their effects. Herein, PS-loaded microneedle (MN) patches with O 2 propellant for a deeper and faster transdermal delivery of PS and improved PDT by embedding sodium percarbonate (SPC) into dissolving poly(vinyl pyrrolidone) MNs are presented. It is shown that SPC in the MNs can react with surrounding fluid to generate gaseous oxygen bubbles, forming vigorous fluid flows and thus greatly enhancing PS of chlorin e6 (Ce6) penetration in both hydrogel models and skin tissues. Reactive oxygen species (ROS) in hypoxic breast cancer cells (4T1 cells) are greatly increased by rapid penetration of PS and relief of hypoxia in vitro, and Ce6-loaded SPC MNs show an excellent cell-killing effect. Moreover, lower tumor growth rate and tumor mass after a 20-d treatment in tumor-bearing mice model verify the improved PDT in gaseous oxygen-droved delivery of PS. This study demonstrates a facile yet effective route of MN delivery of PSs for improved PDT in hypoxic tumor treatment.
研究领域:
生物医学工程
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癌症治疗
·
药物递送系统
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药学科学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
MATERIALS & DESIGN
·
2022
·
IF 9.417
Bo Zhang,Xinyu Li,Weibin Shu,Yu-Shun Yang,Hai-Liang Zhu,Chenwen Shao
Hypothermal photothermal therapy, as a non-invasive therapy method, is becoming ever more prevalent. However, due to cellular heat resistance from the generation of heat shock proteins (HSPs) and the monotonicity of therapeutic modality, the antitumor efficacy is severely restricted. Herein, a self-supplied O 2 multifunctional nanoplatform mediated by glucose oxidase (GOx) is developed, which may combine starvation therapy (ST) and hypothermal photothermal therapy (HPTT) for tumor therapy. The obtained nanoplatform, [email protected] @ [email protected] (UMIGH), was assembled by the UIO-66 core, MnO 2 , indocyanine green (ICG) and hyaluronic acid (HA). GOx was introduced to decrease the ATP level thus alleviating the HSPs-mediated heat tolerance, while the loaded MnO 2 could decompose intratumoral H 2 O 2 into O 2 , which enhanced the effect of HPTT and ST. Due to the coated HA, UMIGH could target the high expressed CD44 in CT26 tumor cells. The active targeting and NPs-associated passive targeting promoted the uptake of nanoparticles. Furthermore, ICG encapsulated in UMIGH NPs could also accurately image tumors. This synergistic treatment strategy of HPTT and ST exhibited an excellent anti-proliferation effect on colon cancer cells in vitro and mouse xenograft model in vivo , which might bring an informatic strategy for future investigations.
研究领域:
纳米技术
·
癌症治疗
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生物医学工程
·
药学
✓ 已验证
产品关联
DOI
高影响因子
BIOSENSORS & BIOELECTRONICS
·
2023
·
IF 12.6
Zepeng Kang,Yuanming Wang,Haiyan Song,Xueli Wang,Yi-Heng P. Job Zhang,Zhiguang Zhu
The performance of biocathode in an enzymatic biofuel cell (EBFC) in the real application is somehow overlooked. Herein, a wearable and flexible lactic-acid/O 2 EBFC enhanced with an air-breathing biocathode is designed to solve the limitation of biocathode that arises from the low solubility and slow mass transfer of the dissolved oxygen. To improve the oxygen supply efficiency for the air-breathing biocathode, a superhydrophobic base electrode creating an efficient air-solid-liquid triphase interface is developed. The designed EBFC with an ‘island-bridge’ configuration is integrated by assembling the current collectors of air-breathing biocathode and bioanode on a commercial laminating film (LF) screen-printed with a noninterfering circuit. It is found that the biocathode/bioanode area ratio should exceed 9:1 so that the designed EBFC (1A//9C) can achieve the optimal performance. This EBFC delivers an open circuit voltage of ca. 0.75 V and outputs a maximum power density of ca. 1.78 mW cm −2 . In addition, a scaled-up EBFC (total bioanode area: 1.5 cm 2 ) successfully powers a self-developed low-power device of heartrate in the pulse operation mode when applied on a volunteer's arm.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
·
2023
·
IF 4.4
Xiaohui Wang,Yuanxiangyi Feng,Zhe Li,Jinhua Liu,Dandan Sun,Wei Yang,Xiaowei Xing,Wenjun Liu,Hongxin Zhang
A fluorescent capillary sensor for detecting the bioanalytically and biologically relevant analytes pH, O 2 , and CO 2 has been designed. The sensor is based on single capillary tube with 2 mm inner diameter, which is simultaneous doped with emissive O 2 -sensitive indicator Ru(dpp) 3 (PF6) 2 (RuDP), pH-sensitive and CO 2 -sensitive indicator 8-hydroxypyrene-1, 3,6-trisulfonic acid trisodium salt (HPTS). The multifunctional sensor can be excited at the same wavelength and realize multi-parameter optical monitoring at the different sensing position. Studies in phosphate-buffered solutions display the excellent feasibility of the capillary sensor for fluorescence detection of pH, O 2 , and CO 2 . Overall, the multifunctional capillary sensor exhibits great potential in real-time blood gas analysis, and clinical application of multi-parameter biological detection.
研究领域:
生物分析学
·
医学工程
·
化学传感
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF ALLOYS AND COMPOUNDS
·
2023
·
IF 6.2
Guiru Sun,Zexu Zhang,Daming Yang,Yan Wang,Wei Lu,Mei Liu,Ming Feng
Li metal is considered as an ideal anode for Li-O 2 batteries because of its unbeatably theoretical specific capacity and low electrode potential. Unfortunately, the growth of Li dendritic and the sensitivity to electrolyte and O 2 hinder the practical applications of Li anode. Herein, AlF 3 as an electrolyte additive is firstly employed in a Li-O 2 battery, which can boost the formation of LiF@Al-Li@Al 2 O 3 -rich SEI film via in-situ spontaneous reactions of AlF 3 with Li anode in O 2 atmosphere. The generated SEI film contributes to inducing the homogeneous nucleation of Li and reducing the disgusting side reactions, which can suppress the growth of Li dendrite and improve the cyclability of Li anode. Benefiting from the rational design, both the Li-O 2 and the Li|Li symmetric batteries with AlF 3 electrolyte exhibit low overpotential and good cycling stability. We hope this work could provide a facile way to in-situ construct a stable SEI film to alleviate the uneven Li nucleation for Li-O 2 batteries.
研究领域:
材料科学
·
电化学
✓ 已验证
产品关联
DOI
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2023
·
IF 15.1
Yilin Yang,Ning Wang,Zhihua Wang,Mingda Han,Fei Yan,Zhan Shi,Shouhua Feng
Sonodynamic therapy (SDT) has emerged as a promising strategy for treating tumors owing to its non-invasiveness and high tissue-penetrating depth. Improving the efficiency of electron-hole separation of sonosensitizers and alleviation of the hypoxic tumor microenvironment remain major challenges. Metal-organic frameworks (MOFs) have greatly potential in SDT application, however, exploring new sonosensitizers with high reactive oxygen species (ROS) generation and improving the efficacy through a synergistic effect in combination with other therapeutic modalities remain major challenges. Furthermore, the immunosuppressive tumor microenvironment (TME) is characterized by hypoxia, which limit the efficacy of O 2 -dependent cancer treatments including SDT and immunotherapy. Herein, we fabricated a defect-rich titanium-based MOFs using propionic acid-mediated self-templated hierarchical etching. Reductive platinum nanoparticles were embedded onto the surface of MOFs to enhance the spatial separation of electron-hole pairs and improve the quantum yield of ultrasound-generated singlet oxygen ( 1 O 2 ). Finally, perfluorobromooctane was encapsulated in the MOFs to function as an oxygen carrier to develop an oxygen self-feeding nanosensitizer. In vitro and in vivo assays demonstrated that this nanoplatform could produce high levels of 1 O 2 under ultrasound irradiation, which led to enhanced SDT. Moreover, this nanoplatform also relieved the immunosuppressive TME by overcoming hypoxia and enhancing immunogenic cell death to promote the infiltration of tumor-specific cytotoxic T cells into the immunologically “cold” tumor. Therefore, combination of nanoplatform-mediated SDT with anti-PDL1 antibodies effectively inhibited the primary tumors, as well as the metastatic tumors. This study provides an insightful strategy for improving SDT and broadens the application of MOF-based sonosensitizers for sono-immunotherapy.
研究领域:
癌症治疗
·
纳米技术
·
生物医学工程
·
材料科学
·
免疫疗法
✓ 已验证
产品关联
DOI
高影响因子
NEW JOURNAL OF CHEMISTRY
·
2024
·Vol. 48
·期 37
·16230-16242
·
IF 2.7
Liang Wei,Sihong Li,Haibo Wang,Zimei Mo,Junji Chen,Meng Li,Hongxi Zhang,Jing Yang,Xiande Yang
Aflatoxin B1 (AFB1), a mycotoxin commonly found in foodstuffs, poses significant health risks when ingested through contaminated food sources. Therefore, it is imperative to devise a safe and efficient method for AFB1 degradation. Graphitic carbon nitride (g-C3N4) stands out as an exceptionally stable, non-toxic, and economical photocatalyst, which is widely used in photocatalysis. In this study, we explored the photocatalytic performance of four g-C3N4 catalysts derived from different precursors (dicyandiamide (D-CN), melamine (M-CN), thiourea (T-CN), and urea (U-CN)) in AFB1 degradation under visible light. Notably, the U-CN catalyst displayed an impressive degradation rate of 93.5% for AFB1 within 30 min, outperforming M-CN (82.5%), T-CN (78.5%), and D-CN (46.2%). This superior performance is attributed to its inherent porous structure, enlarged specific surface area, and reduced electron–hole pairs’ recombination rate. Additionally, our investigation identified ˙O2− as the primary active species in AFB1 degradation. Furthermore, we explored the degradation pathway of AFB1 and its associated inactivation mechanism mediated by the U-CN catalyst. This work provides a theoretical foundation for developing highly efficient photocatalysts in AFB1 degradation.
研究领域:
环境科学
·
化学
·
材料科学
·
毒理学
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）