JOURNAL OF MEMBRANE SCIENCE
·
2015
·
IF 5.056
Junhui Wu,Zhi Wang,Wentao Yan,Yao Wang,Jixiao Wang,Shichang Wang
A commercial polyamide reverse osmosis (RO) membrane was surface modified in a sequential two-step dip coating process for improvement of the hydrophilicity and fouling resistance. In the first step, an ultrathin metal-polyphenol precursor layer was deposited onto the membrane surface via the self-assembly of tannic acid (TA) and Fe(III) ions, and polyethylenimine (PEI) was added as a covalent cross-linker. In the second step, poly(N-vinylpyrrolidone) (PVP), a common hydrophilic polymer , was immobilized onto the metal-polyphenol precursor layer through the strong hydrogen bonding interactions between the lactam groups in PVP and the phenolic hydroxyl groups in the precursor layer. X-ray photoelectron spectroscopy (XPS), scanning electron microscope (SEM), transmission electron microscopy (TEM) and zeta potential measurements confirmed the successful immobilization of the precursor layer and PVP. Atomic force microscopy (AFM) test indicated a smoother surface of the modified membrane. Furthermore, the water flux of the modified membrane was only slightly decreased and the salt rejection was almost unchanged. More importantly, static contact angle measurement showed that the membrane surface hydrophilicity was significantly improved after the PVP immobilization (contact angle from 59.0±1.2° to 14.5±2.4°). Membrane fouling experiments were performed over three “filtration–rinsing” cycles using two proteins (lysozyme and bovine serum albumin) and one polysaccharide (sodium alginate) as model foulants. The results of the fouling experiments revealed that the fouling resistance of the reverse osmosis membrane was obviously improved by the surface immobilization of PVP. Besides, cross-flow filtration test under high hydrodynamic shear condition for 15 days indicated the excellent stability of the immobilized PVP. This work provided a new potential strategy for improving the fouling resistance of RO membranes.
研究领域:
材料科学
·
环境工程
·
化学工程
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产品关联
DOI
高影响因子
JOURNAL OF MEMBRANE SCIENCE
·
2022
·
IF 10.53
Yutang Kang,Jiahao Chen,Shasha Feng,Huixian Zhou,Fangqi Zhou,Ze-Xian Low,Zhaoxiang Zhong,Weihong Xing
Particulate matters (PMs) emissions from energy consumption contribute the vast majority of PM pollution, which are typically associated with high temperatures (>300 °C) and are difficult to remove directly at high temperatures. Electrospinning nanofiber membranes have irreplaceable advantages of high removal efficiency and low pressure drop for PMs filtration, however, the efficient filtration of PMs at high temperature is challenging for polymer-based nanofiber membranes because of the poor heat resistance and inflammability. Herein, we design a thermally-oxidized polyacrylonitrile/polyvinylpyrrolidone/SnO 2 (OPAN/PVP/SnO 2 ) nanofiber membrane by performing the thermally induced cyclization and oxidation reaction of PAN/PVP/SnCl 2 nanofiber membrane at 350 °C in air. During the thermal oxidization process, Sn 2+ acted as a catalyst and activation, preventing the melting and fusion of PAN nanofibers. The addition of PVP greatly increased the mechanical properties of OPAN/SnO 2 nanofiber membrane. The prepared OPAN/PVP/SnO 2 nanofiber membrane possesses superior PMs filtration performance at room temperature, with the PM 0.3 and PM 2.5 filtration efficiency of 99.53% and 99.98%, respectively. The OPAN/PVP/SnO 2 nanofiber membrane exhibits high temperature tolerance up to 350 °C and wide pH tolerance of 1–14, it remains a high PMs removal efficiency of 98.51% at 350 °C and 98.67% at 300 °C. Moreover, the OPAN/PVP/SnO 2 nanofiber membrane shows excellent fire retarding and self-extinguishing property not shown in pristine PAN nanofiber membrane. This work provides a novel approach for clean use of energy via a cost-effective, heat-resistant, and flame-retardant nanofiber membrane.
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DOI
高影响因子
APPLIED SURFACE SCIENCE
·
2024
·
IF 6.3
Yanglei Xie,Jiajun Zhu,Licai Fu,Wulin Yang,Deyi Li,Lingping Zhou
Hydrophilic thermoplastic polyurethane (TPU) is applicable in the fields of packaging, oil–water separation, and biomedical. Nevertheless, the process of its preparation is still a great challenge. The objective of this study is to develop TPU with excellent wettability and hydrophilic stability by surface modification. Four methods were evaluated: coating with PVP (polyvinylpyrrolidone) solution, immersion in PVP solution, N 2 /Ar plasma treatment, and N 2 /Ar plasma-induced graft polymerization with PVP. Finally, the results indicate that the sample called TPU-g-PVP, which utilizes plasma-induced grafting, exhibits the best performance. The water contact angle (WCA) reduces from 109° to 9.2°, and maintains within 20° after 80 days under atmospheric conditions. Its surface energy (72.4 mN/m) is increased by 2.8 times than untreated TPU. The surface morphology and roughness are almost unchanged when compared to the original TPU. Some characteristic peaks (–OH and C = O) of PVP on the TPU-g-PVP were found by infrared spectroscopy. X-ray photoelectron spectroscopy (XPS) examination revealed a reduction in C on the TPU surface as the content of N and O increases. Experiments on biocompatibility showed that the PVP deposited substrates improved cell adherence without generating new cytotoxicity.
研究领域:
材料科学
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表面化学
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高分子科学
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生物医学工程
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DOI
高影响因子
PHARMACEUTICAL CHEMISTRY JOURNAL
·
2024
·Vol. 57
·期 10
·1627-1636
·
IF 0.8
Liu Lang,Ouyang Fenfen,Li Ting,Wen Min,Zha Guodong,Chen Libo,Fu Xue,Zhu Li qing
Celecoxib, the first cyclooxygenase-2 selective nonsteroidal anti-inflammatory drug, has a wide range of pharmacological effects, including anti-inflammatory, antirheumatic and antitumor effects. However, celecoxib’s poor solubility severely limits its clinical application. Thus, a novel ternary solid dispersion system was developed using PVP K30 and hydroxypropyl-β-cyclodextrin (HPβCD) as carrier materials in order to improve its solubility and dissolution behavior. The solid dispersion system was characterized by SEM, XRD, FT-IR, DSC, in vitro dissolution, saturated solubility, and contact angle test; the stability of the samples under extreme environments was investigated as well. The results showed that the novel ternary solid dispersion doped with PVP K30 and HPβCD has enhanced solubility around 6.28-fold, an almost 13.94-fold increase in the dissolution rate (120 min) compared with celecoxib’s active pharmaceutical ingredient. The substantial improvement in its dissolution performance is attributed to the fact that celecoxib is dispersed in the carrier material in an amorphous form and has hydrogen bonding interactions with the carrier materials. In addition, the improvement of wettability is one of the reasons for its increased solubility. In conclusion, the combination of PVP K30 and HPβCD can significantly improve the solubility of celecoxib and this novel solid dispersion system provides new ideas and methods to further improve the solubility of insoluble drugs.
研究领域:
药剂学
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药物技术
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药物传递
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材料科学
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生物药剂学
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DOI
高影响因子
Nature Communications
·
2018
·Vol. 9
·期 1
·1-8
·
IF 12.353
Li Bo,Zhang Yanan,Fu Lin,Yu Tong,Zhou Shujie,Zhang Luyuan,Yin Longwei
Owing to inevitable thermal/moisture instability for organic–inorganic hybrid perovskites, pure inorganic perovskite cesium lead halides with both inherent stability and prominent photovoltaic performance have become research hotspots as a promising candidate for commercial perovskite solar cells. However, it is still a serious challenge to synthesize desired cubic cesium lead iodides (CsPbI 3 ) with superior photovoltaic performance for its thermodynamically metastable characteristics. Herein, polymer poly-vinylpyrrolidone (PVP)-induced surface passivation engineering is reported to synthesize extra-long-term stable cubic CsPbI 3 . It is revealed that acylamino groups of PVP induce electron cloud density enhancement on the surface of CsPbI 3 , thus lowering surface energy, conducive to stabilize cubic CsPbI 3 even in micrometer scale. The cubic-CsPbI 3 PSCs exhibit extra-long carrier diffusion length (over 1.5 μm), highest power conversion efficiency of 10.74% and excellent thermal/moisture stability. This result provides important progress towards understanding of phase stability in realization of large-scale preparations of efficient and stable inorganic PSCs.
研究领域:
材料科学
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光伏技术
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纳米技术
·
能源材料
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DOI
高影响因子
INORGANIC CHEMISTRY
·
2019
·
IF 4.85
Jiannan Lin,Zheng Hu,Hui Li,Jianqiang Qu,Miao Zhang,Wenjie Liang,Shi Hu
Bismuth oxyhalide (Bi-O-X) is a group of layered semiconductors, which are promising candidates for photocatalysis due to their inherent internal electric field and adjustable band gap through composition and morphology control. Bismuth-rich Bi-O-X has improved stability and advantageous band structure compared to those of Bi-O-X and hence has attracted an increasing amount of research interest. In this work, ultrathin nanotubes of Bi5O7I with a 5 nm diameter and a 1 nm wall are obtained through a hydrothermal method while the phase and morphology of the products are regulated by the pH values and polyvinylpyrrolidone (PVP) concentration of the reaction system, of which the products can be tuned from BiOI nanosheets to Bi5O7I nanobelts and ultrathin Bi5O7I nanotubes. PVP and pH control is important to the formation of the nanotubes as formation occurs via a PVP-guided oriented attachment from primary nanoparticles of Bi5O7I. The poorly crystalline and porous structure of the resultant bismuth-rich ultrathin nanotubes not only exposes more surface atoms but also exhibits a highly reduced conduction band minimum. The resultant band gap of 2.39 eV (as compared to 3.20 eV for the nanobelts) arises from the undercoordinated bismuth centers brought about by the rich oxygen vacancies in the nanotubes. The largely reduced band gap effectively enhances visible-light absorption, while the short charge-diffusion length of the nanotubes further reduces the charge-carrier loss in recombination.
研究领域:
材料科学
·
纳米技术
·
光催化
·
半导体物理
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产品关联
DOI
PubMed
高影响因子
Biomimetics
·
2026
·Vol. 11
·期 8
·599
·
IF 4.2
Haiguang Zhang,Feng Jiang,Qianmin Gao,Qingxi Hu,Jiaxuan Feng
Vascular stent implantation is a major treatment for vascular diseases, yet postoperative infection and persistent inflammation increase the risk of in-stent restenosis. Herein, core–shell structured PCL/PEO-PVP fiber membranes co-loaded with ciprofloxacin hydrochloride (CIP) and curcumin (CUR) were fabricated via coaxial electrospinning. Orthogonal experiments were conducted to optimize critical spinning parameters through multi-index comprehensive evaluation. Characterizations confirm intact core–shell architecture and stable polymeric backbone structure. In vitro release tests reveal sequential drug-delivery behavior: a rapid initial release of hydrophilic CIP and a delayed sustained release of hydrophobic CUR were observed, contributing to early-stage antibacterial and long-term anti-inflammatory effects, respectively. The “antibacterial zone” method verifies favorable antibacterial activity againstStaphylococcus aureus(S. aureus) andEscherichia coli(E. coli). ELISA results demonstrate the enhanced anti-inflammatory capacity of the dual-drug-loaded coaxial fiber membrane. Cellular assays confirm satisfactory cytocompatibility, and endothelial cells achieve normal proliferation and exhibit typical polygonal morphology on the membrane surface. This dual-drug-loaded coaxial-fiber membrane realizes coordinated sequential antibacterial and anti-inflammatory properties, which provides a feasible strategy for developing functional coatings toward vascular stents.
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DOI
高影响因子
Surfaces and Interfaces
·
2026
·
IF 6
Wanru Suo,Run Huang,Tao Yang,Hao Yu,Liu Yang,Peixuan Zou,Yusong Pan,Rui Yue,Lei Huang
Metal-organic frameworks (MOFs), such as Cu-MOF, have emerged as highly efficient tumor drug carriers due to their tunable particle size, adequate adsorption property, and good biocompatibility. In this work, Cu-MOFs with different sizes were synthesized by employing a micelle-confined strategy via controlling the concentration of the polyvinylpyrrolidone (PVP) template. At a PVP concentration of 400 mM, the X-ray diffraction (XRD), scanning electron microscopy (SEM), and X-ray photoelectron spectroscopy (XPS) results jointly confirmed that Cu-MOF nanoparticles (named as Cu-MOF- 400 ) with an average grain size of 167 nm were successfully synthesized. The Cu-MOF -400 exhibited a good crystal structure with the regular octahedral morphology, and possessed a pore diameter of about 1.83 nm with the elements (Cu, C, and O) distributed evenly on the surfaces. In vitro co-culturing experiments revealed that the Cu-MOF -400 exhibited low cytotoxicity to 293T cells, while achieving antibacterial inhibition rates of 58.3% and 69.1% against Gram-negative bacteria ( Escherichia coli ) and Gram-positive bacteria ( Staphylococcus aureus ), respectively. With the aid of the pore structure, Cu-MOF- 400 had a drug loading efficiency (DLE) of 78.3% for doxorubicin (DOX) within 24 h, and the DOX-loaded system (named as Cu-MOF -400 @DOX) demonstrated significant pH-responsive drug release properties in the tumor microenvironment (pH 5.2), with a cumulative release rate of 54.75% over 72 h, which is 6.3 times higher compared to that under the physiological conditions (pH 7.4), fitting well to the Korsmeyer-Peppas model. In addition, Cu-MOF -400 @DOX inhibited the survival of HeLa tumor cells to 42.2% (a killing rate of 57.8%) at a concentration of 9 μg·mL -1 , which might be due to the good cellular-uptake effect of the drug-loaded system; as the Cu-MOF -400 @DOX achieved complete intracellular localization within 6 h, which significantly facilitated the acid-triggered DOX release. With good cytocompatibility and bactericidal effect, and after DOX loading, the nanosystem displays excellent pH-responsive drug release to efficiently suppress tumor-cell growth in vitro, offering a new strategy for the development of new-type drugs in clinic for tumor treatment and bacterial resistance prevention.
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DOI
高影响因子
INORGANIC CHEMISTRY COMMUNICATIONS
·
2026
·
IF 5.9
Yaxin Yi,Xian Liu,Zizhe Xiong,Bei Liu,Xiangyun Jiang,Lei Zhu,Xun Wang
Using a simple ‘polymer-assisted pyrolysis–co-precipitation’ strategy, a three-dimensional interlocked CeO 2 /g-C 3 N 4 Z -scheme heterojunction structure with a honeycomb-like morphology was successfully fabricated. In contrast to the morphology of conventional composites, morphological and structural characterisation in this study indicates that the thermal cracking strategy of the polymer template causes partial rupture of CeO 2 microspheres to create pores, driving g-C 3 N 4 to interpenetrate, thereby promoting the interweaving of the two to form a three-dimensional interlocked symbiotic network. Its unique structure not only increases the interfacial contact area but also creates smoother mesoporous transport channels, thereby promoting mass transfer processes. This significantly enhances the degradation kinetics in low-concentration systems. The degradation rate constant k for 5 mg/L phenol is 0.036 min −1 , which is up to 4.9 times higher than that in high-concentration systems. XPS and EIS analyses revealed strong interfacial chemical interactions between CeO 2 and g-C 3 N 4 ; this close interfacial coupling effectively reduced charge transfer resistance. Combined with characterisation methods such as ESR, this suggested that the system promotes the separation of photogenerated carriers along a proposed efficient Z -scheme path, thereby continuously generating large amounts of reactive oxygen species (•O—2 and •OH). The optimal 2–1Ce/CN composite achieved a phenol degradation rate of up to 94.5% for a 5 mg/L solution within 75 min, whilst demonstrating excellent cycling stability. This work provides novel mechanistic insights for the design and development of structurally optimised materials for highly efficient photocatalytic environmental remediation.
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DOI
高影响因子
MICROCHEMICAL JOURNAL
·
2025
·
IF 5.1
Xiaoyue Yue,Chenxu Hao,Chaoyun Wu,Mingsha Jie,Yanhong Bai
Herein, we present a novel magnetic colorimetric immunosensor designed for the ultrasensitive detection of tetracycline. This immunosensor employs Fe₃O₄-TC-mAb conjugates as capture probes and Mn₇O₁₃•5H₂O/PVP-TC-BSA nanozymes as signal probes, operating under a competitive immunoassay format. After magnetic separation of the formed immunocomplexes, the unbound signal probes remaining in the supernatant catalyze the oxidation of 3,3′,5,5′-tetramethylbenzidine (TMB), yielding a distinct colorimetric signal at 652 nm. This enables the quantitative detection of TC over a broad linear range (50–1000 ng/mL) with an ultra-low detection limit of 0.396 ng/mL. The sensor exhibits excellent accuracy, with recoveries ranging from 95.56 % to 100.79 % in spiked milk samples, and facilitates rapid analysis. Compared to conventional methods, this approach offers significant improvements in both sensitivity and operational efficiency, making it well-suited for food safety monitoring. This research lays a foundation for the development of simple, rapid, and ultrasensitive tetracycline detection technologies, with potential applications extending to food safety and environmental monitoring.
研究领域:
免疫学
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生物传感技术
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食品质量安全
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环境监测
·
分子诊断
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产品关联
DOI
高影响因子
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2025
·
IF 8.5
Qian Zhang,Hongwei Wang,Mengxing Chen,Lihong Wang,Xin Che
Infectious burn wounds are characterized by substantial exudate and inflammation. Ordinary wound dressings struggle to absorb substantial exudate. In this study, a color-changeable and separable polylactic acid/polyvinylpyrrolidone/chitosan tri-layer self-pumping dressing containing astragalus polysaccharide was developed. The dressing had an outer layer of polyacrylonitrile/polyvinylpyrrolidone/CoCl 2 nanofiber, a middle layer of polylactic acid/polyvinylpyrrolidone/chitosan nanofiber, and an inner astragalus polysaccharide drug-carrying layer. It could unidirectionally absorb wound exudate and change color after absorbing exudate. In addition, after absorbing the exudate, the outer layer of the dressing could be separated, the remaining double layers consisted of a drug layer and antimicrobial chitosan promoted wound healing and reduced infection. The water absorption rate of the tri-layer nanofibers reached 2770.70 ± 122 % per time, and the water vapor transmission rate was 4585.99 ± 65 g∙m −2 ∙day −1 . The nanofiber dressing promoted the proliferation, migration, and adhesion of L929 cells. After treating burn-infected rats with this dressing for 14 days, the rats' collagen content and anti-inflammatory levels increased. In conclusion, the color-changeable and separable polylactic acid/polyvinylpyrrolidone/chitosan tri-layer self-pumping dressing containing astragalus developed in this study can effectively accelerate wound healing.
研究领域:
生物医学工程
·
纳米技术
·
药学
·
伤口护理
·
高分子科学
·
炎症研究
·
组织工程
✓ 已验证
产品关联
DOI
PubMed
高影响因子
ACS Applied Materials & Interfaces
·
2024
·
IF 8.3
Guangchao Jin,Dongmei Liu,Kaihan Hu,Songyuan Sun,Huigui Wu,Na Fu,Jingbo Chen
The problem of rapid degradation of the operating voltage and discharge specific capacity of lithium-rich layered oxide (LRMs) cathode materials is a major constraint for their commercial application. In this paper, CoS coating with a 3D layered structure assisted by PVP is used to enhance the cycle life and rate performance of the LRMs material. The introduction of PVP has the following effects: (1) it reduces the solubility of CoS in the electrolyte solution and forms a stable CoS coating, and (2) it acts as a nitrogen-containing carbon matrix material and the heteroatomic dopant, and can provide more active sites to improve the conductivity of CoS. In addition, the CoS coating is capable of efficaciously reducing the direct contact area between electrolyte solution and the LRMs material and alleviating the occurrence of harmful interface reactions. The result of this study manifests that after the modification through CoS modification by PVP, the problem of the capacity decay is obviously solved. When the current density is 0.2 C, the highest specific capacity of 248.87 mAh g–1 can be provided. The capacity retention ratio of the LRMs@CoS material is 87.21% after 100 cycles, and the capacity decay is 0.3182 mAh g–1 (1.1534 mAh g–1 for the LRMs material) per cycle. When the current density is 1 C, the first discharge specific capacity of 220.91 mAh g–1 is achieved, which demonstrates outstanding electrochemical performance. This study has come up with a simple and practical mentality to realize the modification of cathode materials for high-performance lithium-ion batteries.
研究领域:
材料科学
·
电化学
·
储能技术
·
锂离子电池
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DOI
高影响因子
危险品化学品经营许可证（带存储）