JOURNAL OF LUMINESCENCE
·
2015
·
IF 2.719
ShaoZhen Wang,Jianguo Zhang,Hongqi Chen,Lun Wang
A new serum ferritin (SF) biosensor based on fluorescence resonance energy transfer (FRET) from Mn 2+ -doped NaYF 4 :Yb,Tm up-converting rare-earth nanophosphors (UCNPs, donor) to gold nanorods (GNRs, acceptor) was developed in the near-infrared (NIR) region. The as-prepared Mn 2+ -doped NaYF 4 :Yb,Tm UCNPs exhibited a strong emission at 807 nm in the NIR region and were modified with poly-(acrylic acid) (PAA) before conjugating with anti-SF (Ab 1 ). The negatively charged donor (Ab 1 -UCNPs) and the positively charged acceptor (GNRs) were mixed in close proximity due to electrostatic interactions, which quenched the fluorescence emission of the Mn 2+ -doped NaYF 4 :Yb,Tm UCNPs. However, added SF combines with the anti-SF because the binding affinity between SF and Ab 1 is stronger than the electrostatic interactions. Thus, the acceptor separated from the donor, and the fluorescence was restored. Under optimal conditions, the restored fluorescence exhibited a linear relationship with SF concentrations ranging from 0.23 to 16.88 ng/mL and a limit of detection as low as 0.12 ng/mL. The proposed method was also used to monitor SF in human serum samples.
✓ 已验证
产品关联
DOI
高影响因子
NEW JOURNAL OF CHEMISTRY
·
2013
·Vol. 37
·期 10
·3024-3029
·
IF 2.966
Yinhua Jin,Jianhua Liu,Quan Zheng,Jun Xu,Bhoj Raj Sharma,Guilin He,Min Yan,Lin Zhang,Yang Song,Tao Li,Qinghai Yuan,Yong Sun,Haishan Yang
Molecular imaging techniques have shown increasing potential in the definition and imaging of the structure and function of biological systems for preclinical applications. Herein, we report a high-quality dual-modal imaging platform based on water-stable gadolinium-doped Yb(OH)CO3 nanoparticles. These nanoprobes were prepared via a one-pot method, meeting the criteria for a biomedical material. Compared with iobitridol, which is routinely used in clinical applications, our Yb(OH)CO3:Gd nanoparticles provided greatly enhanced contrast at regularly used clinical voltages. By virtue of their doping with gadolinium, these well-designed nanostructures could also be applied as an excellent MRI nanoprobe, which provided similar biodistribution results with our CT experiments. Detailed in vitro and in vivo toxicological study indicated that the uniformly sized nanoparticles possessed high biocompatibility and also low toxicity, making them safe for clinical use. The concept presented here shows great potential for the design and synthesis of nanoprobes with high imaging efficiency and low systemic toxicity.
✓ 已验证
产品关联
DOI
高影响因子
CRYSTENGCOMM
·
2015
·Vol. 17
·期 31
·5900-5905
·
IF 4.034
Bin-Bin Ding,Kun Liu,Fu Zhang,Yang Wang,Sheng Cheng,Yang Lu,Hai-Sheng Qian
Upconversion fluorescent nanostructures with controlled sizes and morphologies have attracted much attention due to their potential and important applications in bioimaging, photodynamic therapy, solar cells and so on. In this work, we describe a facile successive process to fabricate β-NaGdF4:Yb,Er nanocrystals coated with an ultrathin layer of CaF2 with enhanced upconversion fluorescence and stability. The as-prepared β-NaGdF4:Yb,Er@CaF2 nanoparticles were investigated by X-ray diffraction (XRD), transmission electron microscopy (TEM, JEM 21000), fluorescence spectroscopy (Hitachi High-Technology Corporation, F-2700) and inductively coupled plasma atomic emission spectroscopy (ICP-AES). The as-prepared core–shell nanoparticles show enhanced upconversion fluorescence and superior magnetic resonance (MR) relaxivity. In addition, the as-prepared β-NaGdF4:Yb,Er@CaF2 nanoparticles show enhanced chemical stability after surface functionalization and transfer into aqueous solutions.
✓ 已验证
产品关联
DOI
高影响因子
Analytical Methods
·
2017
·Vol. 9
·期 20
·2977-2982
·
IF 1.9
Yuanhui Ma,Liping Zhang,Lei Wang,Lun Wang,Hongqi Chen
A novel surface plasmon resonance (SPR) enhanced upconversion (UC) luminescence system was designed for the detection of α-fetoprotein (AFP) by using gold nanoparticle (NP) coated NaYF4:Yb,Er,Gd upconversion nanoparticles (UCNPs) as probes. The gold NP coated NaYF4:Yb,Er,Gd UCNPs had a strong emission at 665 nm and were modified with poly(acrylic acid) (PAA) before being conjugated with anti-AFP (Ab1). When the AFP antigens were added to the system, the binding affinity between AFP and Ab1 resulted in a reduced distance between the gold NP coated UCNPs. The UC luminescence intensity of this system was enhanced because of the SPR properties of the gold NPs. The sensing system exhibited a high sensitivity, good specificity, and wide linear range, 0.098–15.0 ng mL−1 for the detection of AFP (R = 0.99), with a detection limit as low as 0.095 ng mL−1 under optimal conditions. The method was successfully applied to AFP sensing in human serum samples.
✓ 已验证
产品关联
DOI
高影响因子
PHYSICAL CHEMISTRY CHEMICAL PHYSICS
·
2017
·Vol. 19
·期 47
·31675-31683
·
IF 4.123
Zhichao Yu,Haifeng Zhou,Guangjun Zhou,Juan Zhou,Yaqiang Wu,Xingshuang Zhang,Tao Wang,Dapeng Huang,Xinqiang Wang,Jifan Hu
The energy-upconversion of lanthanide-doped nanoparticles with a core–shell structure can be utilized to enhance and tune optical properties and can generate multifunctionality in a single system. Herein, the core–shell nanoparticles NaYF4:Yb,Ho,Tm@NaGdF4 were prepared by thermally decomposing lanthanide acetylacetonate precursors. Through modifying the molar ratio of the core and shell, nanodumbbell-shaped particles with different sizes and morphologies were precisely synthesized. The formation mechanism and the heterogeneous epitaxial growth process of the nanodumbbell-shaped particles were studied. After coating the shell layer, upconversion luminescence intensities, spectral purity and fluorescence lifetimes were improved. Furthermore, the magnetic performance of the core–shell nanoparticles was characterized. The optical–magnetic bifunctional upconversion core–shell particles with programmable shape and multiple properties provide an ideal platform for the preparation of nanodumbbell-shaped particles and the promotion of upconversion materials for biomedical research.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF LUMINESCENCE
·
2024
·
IF 3.3
Chun Liu,Zhenggang Zou,Jiawei Zhu,Jinsheng Liao,Yijian Sun,Herui Wen,Guoliang Gong
The ordered and stable structure of inorganic lattice is the basis of constructing high-efficiency rare earth activated fluorescence, solid-state laser or other optical materials. The mixed sensitized and activated rare earth ions usually keeps a uniform space-occupying and the energy transfer depends much on the doping concentration, while the aggregation of rare earth dopants in order is rare. In this work, a series of LuMgGaO 4 phosphors were synthesized and the detail lattice parameters are analyzed through Vietveld refinement and the new CIF file is provided. The site-occupancy of Er 3+ , Yb 3+ shows clustered features and the Er–Yb sublattice structure with various Yb/Er ratios were constructed on the basis of planar triangular lattice. The long-distance excitation energy migration to lattice or defects can be effectively inhibited in case of the hexagonal circle Er-6Yb sublattice, in which the most intense green/red UCL was obtained. All the results demonstrate the novelty of regulating ordered site-occupancy of rare earth ions on a compact planar triangular lattice with higher efficiency of energy migration, which will pave a way for developing phosphor-converted materials or laser materials with better performance.
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF PHYSICAL CHEMISTRY B
·
2012
·
IF 3.696
Jiebing Ma,Peng Huang,Meng He,Liyuan Pan,Zhijun Zhou,Lili Feng,Guo Gao,Daxiang Cui
Development of multimodal contrast agents for in vivo simultaneous multimodality imaging is an emerging interdiscipline that is paving the avenue toward the goal of personalized medicine. Herein, folic acid-conjugated silica-modified LaF3:Yb,Tm upconversion nanoparticles (UCNPs@SiO2-FA) with high La content in a single particle were strategically designed and prepared for simultaneously targeting dual-modality imaging of upconversion luminescence (UCL) and X-ray computed tomography (CT). LaF3 UCNPs were synthesized by a novel oleic acid (OA)/ionic liquid (IL) two-phase system. Afterward, a folic acid molecule was covalently anchored on the surface of UCNPs with a silane coupling agent. The UCNPs@SiO2-FA exhibits good stability, water dispersibility and solubility, low cytotoxicity, good biocompatibility, highly selective targeting, excellent X-ray attenuation, and UCL emission under excitation at 980 nm. In vivo UCL and CT images of mice show the UCNPs@SiO2-FA can be used in targeting dual-modality imaging. These results suggest that the as-prepared nanoprobe is a good candidate with excellent imaging and targeting ability for targeting dual-modality imaging of UCL and CT.
研究领域:
生物医学工程
·
纳米医学
·
分子影像学
✓ 已验证
DOI
PubMed
高影响因子
JOURNAL OF MATERIALS SCIENCE-MATERIALS IN ELECTRONICS
·
2026
·Vol. 37
·期 15
·1145
·
IF 3.2
Mao Tan,Wang Wei,Liu Peilong,Zha Junyan,Bu Xiran,Song Rui,Luo Xueke
To overcome the intrinsic limitations of TiO 2 , specifically its wide band gap and rapid photogenerated carrier recombination, for dyeing wastewater treatment, a Yb 3+ /Er 3+ co-doped TiO 2 -ZnO heterostructure was fabricated by sol–gel method. X-ray diffraction revealed inhibited anatase-to-rutile phase transition. X-ray photoelectron spectroscopy confirmed Ti 2p binding energy shifts, indicating strong electronic interactions between dopants and the host lattice. Ultraviolet–visible diffuse reflectance spectroscopy showed band gap narrowing to 2.927 eV, with upconversion effect extending light absorption to the near-infrared region. Photoluminescence measurements demonstrated suppressed carrier recombination, and XPS confirmed abundant oxygen vacancies. The optimal sample achieved 74.31% methylene blue degradation under visible light for 6 h and 98.58% under ultraviolet light for 2 h, outperforming commercial P25. The Yb 3+ /Er 3+ co-dopants serve dual functions: they act as upconversion centers to harvest low-energy photons and function as electronic modulators that induce Ti 2p binding energy shifts and create oxygen vacancies, thereby enhancing charge separation and surface reactivity. This work integrates rare-earth co-doping with heterojunction engineering to boost TiO 2 photocatalysis.
✓ 已验证
DOI
高影响因子
ACS Applied Materials & Interfaces
·
2026
·Vol. 18
·期 30
·41290-41310
·
IF 7.8
Weng Tianfeng,Lamon Simone,Gan Zongsong,Gu Min,Zhang Qiming
All-optical data encoding provides a route to ultrafast, low-energy photonic memory and computation, yet its implementation is hindered by weak nonlinearities and low emission efficiencies in conventional materials. Upconversion luminescence offers strong nonlinear behavior, but typical hosts suffer from inefficient energy transfer, dilute and randomly distributed dopants, and complex excitation demands. Here, we report thermally crystallized BaYF 5 :Yb,Er glass-ceramics that overcome low upconversion efficiency and dopant inhomogeneity through controlled Er 3+ enrichment within BaYF 5 nanocrystals. Thermal crystallization reduces interionic distances, promoting cooperative Yb 3+ –Er 3+ sensitization and Er 3+ –Er 3+ energy migration. The combination of theoretical modeling and experiments shows efficient population of high-energy emitting states, yielding ultrabright upconversion emission with enhancement factors of 113-, 118-, and 110-fold for the blue, green, and red channels under 980 nm excitation. Optimized nanocrystals also prolong emission lifetimes, suppress nonradiative relaxation, and produce clear saturation behavior. Leveraging strongly nonlinear responses, power- and pulse-width-modulated excitation enables precise control of both spectral and temporal outputs, forming a highly reconfigurable platform. This allows multidimensional data encoding and implementation of fundamental optical logic gates with high fidelity and self-referenced decoding. The system offers robust, secure, and scalable functionality for advanced all-optical information processing applications.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY
·
2019
·
IF 3.261
Zhengquan Liu,Lan Yang,Min Chen,Quansheng Chen
In this work, a label-free fluorimetric method for sensitive and selective detection of Cr(III) was developed by utilizing NaY/GdF 4 :Yb,Er upconversion nanoparticles (UCNPs) and citrate-modified silver nanoparticles (Cit-AgNPs) mixed system. The photophysical and morphological properties of the prepared UCNPs were characterized by various spectroscopic and microscopic techniques. The fluorescence of amino-modified UCNPs can be quenched due to the Cr(III) induced aggregation of Cit-AgNPs by means of inner filter effect. The observed quenching in the fluorescence intensity of the UCNPs is found to be dependent on the concentration of Cr(III). The fluorescence decreases linearly within the investigated concentration of 0.5–40 μM Cr(III) with a limit of detection 34 nM. The practical applicability of the present sensing method is ascertained by detecting Cr(III) in spiked tap water and instant tea samples.
研究领域:
分析化学
·
纳米技术
·
环境科学
✓ 已验证
DOI
高影响因子
CRYSTENGCOMM
·
2022
·Vol. 25
·期 1
·95-107
·
IF 3.756
Lei Wang,Xudong Liu,Jinsheng Li,Mu Zhang,Xiaoguo Bi,Zhixin Ma,Jialin Chen,Xudong Sun
High-performance dielectric materials are essential components of electronic devices. In this work, RE-doped SrTiO3 (RE = La, Nd, Yb) single crystals with excellent dielectric properties were prepared by the Verneuil method. For La-STO and Nd-STO, the RE ions are substituted for Sr2+ only, and the excellent dielectric properties are mainly caused by defect dipoles associated with oxygen vacancies including and defect dipole clusters. For Yb-STO, Yb3+ partially replaces Ti4+, forming an additional defect dipole , resulting in the best dielectric properties (ε′ = 3.6 × 104, tan δ = 0.0036 under 1 kHz). In addition, N2 atmosphere treatment promotes the production of oxygen vacancies and Ti3+ and the formation of more defect dipoles, thus further optimizing the dielectric properties of Yb-STO (ε′ = 4.9 × 104, tan δ = 0.004 under 1 kHz). This work suggests that the dielectric properties of RE-doped SrTiO3 materials are closely related to oxygen vacancies, and the simultaneous substitution of Sr2+ and Ti4+ should enable obtaining dielectric properties superior to those of the substitution of Sr2+ only. The present work provides a clearer understanding of the origin of SrTiO3 dielectric properties, which is of great significance to the development of SrTiO3-based dielectric materials.
研究领域:
材料科学
·
凝聚态物理
·
电子器件
✓ 已验证
DOI
高影响因子
Journal of Materials Chemistry C
·
2022
·Vol. 10
·期 42
·15897-15905
·
IF 8.067
Hanchang Huang,Maohui Yuan,Zhongyang Xing,Wenda Cui,Tongcheng Yu,Shuai Hu,Guomin Zhao,Chuan Guo,Kai Han
In lanthanide-sensitized upconversion (UC) nanomaterials, the typical sensitizer Yb3+ can significantly modulate the codoped activator (such as Er3+ ions) to generate multiband transitions. However, the kinetics of these multiband emissions affected by the Yb3+ concentration remains unclear. In this work, we employ nanosecond time-resolved spectroscopy to investigate a single optically trapped NaYF4:Yb/Er microcrystal (MC) doped with different Yb3+ concentrations. Interestingly, high doping Yb3+ ions shorten the UC response time by a factor of 10 (from ∼1 μs to ∼100 ns) compared to low doping Yb3+. Meanwhile, 430 nm light (4G7/2 → 4I11/2) emitted before 654 nm (4F9/2 → 4I15/2) with Yb3+ dramatically increasing (opposite to the normal low Yb3+ doping cases), representing a new four-photon pathway (4I15/2 → 4I11/2 → 4F7/2 → 2H11/2 →4S3/2 → 2G7/2 → 4G11/2 → 2H9/2 → 2D5/2 → 4G7/2). Furthermore, we observed a broad range of time-dependent emission color, changing from being initially green over near-white to red. Particularly, the red emission is dominated in the decay process, yielding insight into the fundamental multiband UC kinetics. The result shows that varying the Yb3+ doping concentration provides a way to control the energy flow between the energy levels of Er3+ ions, which can modulate the response time and color evolution of UC on Yb/Er doped materials. This can direct the prospective development of fast-response optoelectronic devices, photocatalysis, and UC displays in the future.
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）