INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2024
·
IF 7.7
Hao Cheng,David Julian McClements,Hao Xu,Zipei Zhang,Ruojie Zhang,Jianwei Zhao,Hui Zhou,Wu Wang,Zhengyu Jin,Long Chen
With an increasing emphasis on environmental protection and sustainability, natural polymers like proteins and polysaccharides are being utilized more frequently in the development of biodegradable food packaging. However, the limited properties of these biopolymers have restricted their widespread applicability within the food industry. To address this issue, eugenol-loaded zein nanoparticles (ZE NPs) were incorporated into pea starch/soy protein-based films, and their effect on the physicochemical properties of these films were investigated. The ZE NPs exhibited high compatibility with the pea starch-soy protein isolate (PES/SPI) matrix, enhancing the structural properties of the films by forming hydrogen bonds between the nanoparticles and the biopolymer network. Incorporating the nanoparticles enhanced the mechanical properties, thermal stability, ultraviolet shielding, surface hydrophobicity, and moisture barrier performance of the films. Furthermore, the films containing ZE NPs exhibited significant antioxidant and antibacterial activity, suggesting their potential application as preservatives in active food packaging materials. In conclusion, the incorporation of ZE NPs significantly enhanced the performance of PES/SPI-based films, which should expand their application as food packaging materials.
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高影响因子
FOOD CHEMISTRY
·
2024
·
IF 8.5
Haoning Yang,Yu Mu,Dan Zheng,Tess Puopolo,Lejie Zhang,Zhuo Zhang,Sai Gao,Navindra P. Seeram,Hang Ma,Xueshi Huang,Liya Li
Guavinoside B (GUB) is a characteristic constituent from guava with strong antioxidant activity ; however, its low water solubility limits its utilization. Herein, we investigated the interaction between GUB and zein , a prolamin with self-assembling property, using multiple spectroscopic methods and fabricated GUB-zein-NaCas nanoparticles (GUB- Z -N NPs) via the antisolvent coprecipitation approach. GUB caused fluorescence quenching to zein via the static quenching mechanism. Fourier-transform infrared spectroscopy and computational analysis revealed that GUB bound to zein via van der Waals interaction , hydrogen bond , and hydrophobic forces. The GUB- Z -N NPs were in the nanometric size range (< 200 nm) and exhibited promising encapsulation efficiency and redispersibility after freeze-drying. These particles remained stable for up to 31 days at 4 °C and great resistance to salt and pH variation, and displayed superior antioxidant activity to native GUB. The current study highlights the potential of zein-based nanoparticles as delivery vehicles for GUB in the food industry.
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INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2024
·
IF 7.7
Xiao-Jie Yue,Peng-Wei Xu,Xiao-Chuan Luo,Bing Zhao
The purpose of this study was to compare and characterize the theoretical properties and interaction mechanisms of zein and isoquercetin (ISO) from experimental and theoretical perspectives. Zein nanoparticles with different ISO concentrations (ZINPs) were prepared by the antisolvent precipitation method. The experimental results indicated all particles appeared spherical. When the mass ratio of zein to ISO was 10:1, the encapsulation efficiency of ZINPs reached 88.19 % with an average diameter of 126.67 nm. The multispectral method and molecular docking results confirmed that hydrogen bonding and van der Waals force played a dominant role for the binding of ISO to zein, and the primary fluorescence quenching mechanism for zein by ISO was static quenching. Furthermore, ZINPs had greater solubility and antioxidant activity, as well as inhibited the release of ISO during simulated gastrointestinal digestion processes. This research contributes to the understanding of the non-covalent binding mechanism between zein and ISO, providing a theoretical basis for the construction of ISO active carriers.
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JOURNAL OF FOOD ENGINEERING
·
2024
·
IF 5.3
Lingyu Yin,Yuhang Cao,Yi Deng,Fei Li,Baohua Kong,Qian Liu,Hui Wang
The role of nanoparticles in the stabilizing interface is very important in the preparation of stable Pickering emulsions. In this study, ternary composite nanoparticles (ZQ-HC) were synthesized by complexing zein-quercetin covalent complex (ZQ) with quaternary ammonium chitosan (HTCC) and subsequently stabilized Pickering emulsions (ZQ-HC) with antibacterial activity. Results revealed that HTCC covers the surface of ZQ nanoparticles successfully, which designates an effective improvement in the surface wettability of ZQ effectively. Among them, ZQ-HC 2:1 possesses the closest three-phase contact angle of 90° and the highest emulsification activity and emulsion stability. The results of ultra-high resolution microscopy showed that ZQ-HC nanoparticles were adsorbed at the oil-water interface to prevent droplet aggregation and improved the pH, ionic strength, and storage stability of the prepared Pickering emulsions. ZQ-HC nanoparticles construct an antioxidant barrier at the oil-water interface, improving the lipid oxidation stability of the emulsion. The ZQ-HC 2:1 stabilized Pickering emulsion exhibits the most superior stability and strongest antibacterial activity against other emulsions. The ZQ-HC stabilized Pickering emulsions prepared in this study exhibit potential for use as carriers of bioactive ingredients in food applications.
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INDUSTRIAL CROPS AND PRODUCTS
·
2024
·
IF 5.6
Jiayuan Tian,Jiyun Xie,Li Hao,Huayao Chen,Xinhua Zhou,Hongjun Zhou
Inefficient use of pesticides and the consequent environmental problems have led to the development of low-cost, environment-friendly and efficient pesticide delivery systems. Pickering emulsions (PK) stabilized by zein are considered to have many application prospects in the delivery of pesticides. Herein, the function of zein was improved by non-covalent binding with sodium abietate (RA-Na). Tea tree oil (TTO) was used as the solvent for hydrophobic photosensitive pesticide, avermectin (AVM), and also as a component of the oil phase of emulsion. The emulsion AVM@PK was oil in water (O/W) type that had certain foliar affinity. Under the same conditions of UV irradiation, the AVM residual rate of AVM@PK system was 2.4 times that of commercial emulsion (EC), showing superior UV resistance. AVM@PK released AVM at a faster rate under acidic/ basic conditions in vitro than under neutral conditions, with a certain pH response. In vitro bioactivity tests showed that AVM@PK had good antibacterial activity and insecticidal activity equivalent to EC. This system is expected to be used to prevent some plant pests while also preventing or treating some bacterial diseases. It is a simple, environment-friendly, low-cost, effective, and practical strategy for pesticide delivery.
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FOOD CHEMISTRY
·
2025
·
IF 9.8
Zhouliang Sun,Yufei Zhang,Huanyu Zheng,Yi Zhang,Yang Li,Mingming Zheng
This study aims to construct a food-grade Pickering emulsion stabilized by zein-hydroxypropyl chitosan composite nanoparticles ( Z -HPCS NPs) adsorbed with lipase CRL (Z-HPCS NPs@CRL) to synthesize phytosterol esters. Uniform spherical Z-HPCS NPs with a strong positive charge (39.2 ± 0.4 mV) were fabricated and complexed with negatively charged lipase CRL to stabilize the emulsion interface. Comprehensive characterization revealed that lipase CRL bound to Z -HPCS NPs through synergistic electrostatic interactions and hydrogen bonding. Furthermore, the unique interfacial characteristics of the Pickering emulsion enable efficient migration of by-product (water) from the oil phase to the aqueous phase, driving the equilibrium towards product formation. The Pickering emulsion system stabilized by Z -HPCS NPs@CRL achieved exceptional phytosterol ester yield (90.9 % in 3 h), surpassing both traditional biphasic systems (15.8 %) and free lipase CRL (82.2 %). This work provides fundamental insights into food-grade Pickering emulsion interfacial biocatalysis for the efficient synthesis of phytosterol esters.
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INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2025
·
IF 8.5
Bo Liu,Xia Liu,Xiaonan Huang,Shouwei Yin,Jianhua Zhu
Freshwater scarcity represents a critical global crisis, necessitating advanced sustainable water purification technologies. While solar-driven interfacial evaporation (SDIE) emerges as an energy-efficient solution, conventional photothermal conversion materials often rely on energy-intensive synthesis or non-renewable resources, compromising their environmental sustainability. Herein, we present a sustainable synthesis paradigm that harnesses zein, a plant-derived biological macromolecule, to develop the metal-phenolic networks (MPNs)-reinforced porous architecture for SDIE system. Zein nanoparticles were functionalized through coordination-driven self-assembly with Fe 3+ and proanthocyanidin, forming ZP-PA/Fe 3+ hybrid particles that serve dually as Pickering emulsion stabilizers and photothermal agents. These particles precisely integrated into a poly(vinyl alcohol) matrix via Pickering emulsion templating, yielding a hierarchical porous scaffold. The optimized P-ZF evaporator achieved an evaporation rate of 2.24 kg·m −2 ·h −1 under 1 sun—exceeding most reported MPN-coated systems (typically ~1.43–1.85 kg·m −2 ·h −1 )—while also demonstrating long-term operational stability, retaining ~90 % efficiency after two years of ambient storage. This study not only validates MPNs-functionalized porous platforms as high-efficiency solar water evaporators but also provides a green synthesis protocol, circumventing the sustainability limitations of conventional synthetic routes.
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FOOD HYDROCOLLOIDS
·
2019
·
IF 5.839
Xulin Huang,Ye Liu,Yan Zou,Xiao Liang,Yaqi Peng,David Julian McClements,Kun Hu
Zein-pectin core/shell nanoparticles loaded with resveratrol were fabricated using a combination of the antisolvent precipitation and electrostatic deposition methods. These nanoparticles were stable to aggregation from pH 2 to 7 and had good heat stability (80 °C for 1 h). The nanoparticles were exposed to a simulated gastrointestinal tract (GIT) containing stomach and small intestine phases, and their bioaccessibility and antioxidant capacity were then measured. The bioaccessibility of the encapsulated resveratrol was higher than that of free resveratrol. Moreover, the in vitro antioxidant capacity of resveratrol was greatly enhanced when it was encapsulated inside the biopolymer nanoparticles, as shown by more potent ABTS + · radical scavenging and ferric ion reducing power. The gastrointestinal fluids collected after digestion of the encapsulated resveratrol also exhibited strong intracellular reactive oxygen species scavenging activity. Our results suggest that the biopolymer nanoparticles produced in this study may be an effective oral delivery system for resveratrol that could be used in functional foods or nutraceutical supplements.
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高影响因子
FOOD HYDROCOLLOIDS
·
2021
·
IF 9.147
Jian-Feng Zhou,Guo-Dong Zheng,Wen-Jun Wang,Zhong-Ping Yin,Ji-Guang Chen,Jing-En Li,Qing-Feng Zhang
Two quercetin loading zein nanoparticles with shell of caseinate (SC-ZNP) and caseinate-chitosan double layer (CHC-ZNP) were fabricated by anti-solvent method. The formulas of the two nanoparticles were optimized and their physicochemical properties and bioavailability enhancement effect were compared in both in vitro and in vivo. The particle size, zeta potential , encapsulation efficiency and loading efficiency of SC-ZNP were 188 nm, −29.33 mV, 82.78% and 1.58%, while these values for CHC-ZNP were 551 nm, + 57.47 mV, 78.26% and 2.91%, respectively. Physicochemical characterization showed that quercetin lost its crystalline structure and existed in amorphous form in both nanoparticles. After freeze-drying, SC-ZNP showed better redispersibility and smaller size change than CHC-ZNP. Both nanoparticles significantly improved the solubility and passive diffusion velocity of quercetin. The coating of caseinate shell provided better colloidal stability (pH, salt and storage) than caseinate-chitosan double layers. Both SC-ZNP and CHC-ZNP exhibited mucoadhesive properties and significantly decreased the feces excretion of quercetin in rat. Because of smaller particle size, SC-ZNP penetrated into the mucous layer more easily. After oral administration, few free quercetin was found in rat plasma, while many metabolites were detected. Through semi-quantification of its most dominant metabolite, the bioavailability of quercetin in SC-ZNP and CHC-ZNP groups were 2.34 and 1.89 times enhanced.
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JOURNAL OF FOOD ENGINEERING
·
2020
·
IF 4.499
Meng-Jing Teng,Yun-Shan Wei,Teng-Gen Hu,Yuan Zhang,Kun Feng,Min-Hua Zong,Hong Wu
To improve the stability of zein core-shell structure microcapsule and realize intestine-specific release of lipophilic bioactive compounds , the β-carotene-loaded microcapsule was prepared by zein cross-linked with citric acid (CA) for the first time. The antioxidant activity of β-carotene was not affected by preparation process. Compared to uncross-linked microcapsule (UCM), the CA cross-linked microcapsule (CCM) had higher β-carotene encapsulation efficiency (94.4% vs. 91.4%), greater shell thickness (161 nm vs. 140 nm) and denser shell structure. Additionally, the CCM had better stability under thermal, freeze-thaw and ionic strength treatments. The fourier transform infrared spectra (FTIR) and circular dichroism (CD) analysis showed that there existed hydrogen bonding and interactions between zein and CA, and differential scanning calorimetry (DSC) and X-ray diffraction (XRD) data revealed the thermal stability and crystallinity intensity of zein/CA complex were improved. The CCM was more stable in simulated gastric fluids and β-carotene bioaccessibility was significantly improved in simulated intestine fluids (72.4% vs. 48.5%).
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Journal of Food Measurement and Characterization
·
2022
·Vol. 16
·期 5
·3618-3629
·
IF 3.006
Song Jialin,Jiang Lijun,Qi Mingming,Li Xiaoyu,Li Ruihong,Ma Chengye,Chen Shanfeng,Li Hongjun,Zhang Dongliang
An alkaline-trigged release of microparticle was prepared. The microparticle was prepared by extruding the mixture of corn starch, zein and procyanidins, and the characteristics of microparticle were detected. The 90% of procyanidins was released at the beginning in pH9 buffer solution and decreased following the chasing time. Even under the extreme alkaline condition (pH 11), approximately 50% of procyanidins was detected after 2 days chasing. The microparticle prepared by extruding the mixture of corn starch and procyanidins (SP) and microparticle prepared by extruding the mixture of corn starch, zein and procyanidins (SZP) showed high antioxidant ability, and the SP displayed five times more ABTS·+ scavenging ratio than SZP. Both of them maintained the constant procyanidins release ratio of 60% and 15% in digestive juice, respectively. The change of morphology, disintegration of crystal and breakage of chemical bonds specified the relationship between procyanidins release and damage of microparticle structure. Graphical abstract
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INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
·
2022
·Vol. 23
·期 16
·9386
·
IF 6.208
Yan Xu,Zhe Jia,Jiaxing Wang,Jipeng Sun,Ru Song
Astaxanthin loaded Pickering emulsion with zein/sodium alginate (SA) as a stabilizer (named as APEs) was developed, and its structure and stability were characterized. The encapsulation efficiency of astaxanthin (Asta) in APEs was up to 86.7 ± 3.8%, with a mean particle size of 4.763 μm. Freeze-dried APEs showed particles stacked together under scanning electronic microscope; whereas dispersed spherical nanoparticles were observed in APEs dilution under transmission electron microscope images. Confocal laser scanning microscope images indicated that zein particles loaded with Asta were aggregated with SA coating. X-ray diffraction patterns and Fourier transform infrared spectra results showed that intermolecular hydrogen bonding, electrostatic attraction and hydrophobic effect were involved in APEs formation. APEs demonstrated non-Newtonian shear-thinning behavior and fit well to the Cross model. Compared to bare Asta extract, APEs maintained high Asta retention and antioxidant activity when heated from 50 to 10 °C. APEs showed different stability at pH (3.0–11.0) and Na+, K+, Ca2+, Cu2+and Fe2+conditions by visual, zeta potential and polydispersity index measurements. Additionally, the first order kinetics fit well to describe APEs degradation at pH 3.0 to 9.0, Na+, and K+conditions. Our results suggest the potential application of Asta-loaded Pickering emulsion in food systems as a fortified additive.Keywords:astaxanthin;Pickering emulsion;zein/sodium alginate complex;structure characterization;stability;degradation kinetics
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