DIAMOND AND RELATED MATERIALS
·
2023
·
IF 4.1
Huajun Zhou,Haifeng Cao,Yongping Qu,Yanzhong Wang
Molybdenum oxides are widely used as electrocatalysts due to their polymetallic oxidation state, abundant reactive sites and low production cost. However, the low electrical conductivity and easy agglomeration has limited their practical application. Here, MoO 3 nanowires encapsulated with ZIF-67 polyhedra were grown in situ on expanded graphite paper (EGP) by a simple hydrothermal synthesis method, and then the precursors were pyrolyzed to obtain self-supported Co-MoO x @N-doped carbon/EGP composites. Thanks to the three-dimensional porous structure and the synergistic effect of Co and multi-valance MoO x , the as-prepared Co-MoO x @N-doped carbon/EGP exhibits the excellent performances of OER (η 10 = 256 mV) and HER (η 10 = 138 mV), and a small Tafel slope and good durability. Furthermore, the assembled water splitting device achieved a current density of 10 mA cm −2 at a low voltage of 1.62 V and the excellent stability after 24 h continuous water splitting.
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JOURNAL OF DRUG TARGETING
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2023
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IF 4.5
Jing Huang,Shan Xu,Lina Liu,Jiyuan Zhang,Jinzhuan Xu,Lili Zhang,Xiang Zhou,Lei Huang,Jianqing Peng,Jianing Wang,Zipeng Gong,Yi Chen
Macrophages are the most abundant cell group in atherosclerosis (AS) lesions and play a vital role in all stages of AS progression. Recent research has shown that reactive oxygen species (ROS) generation from photodynamic therapy (PDT) induces macrophage autophagy to improve abnormal lipid metabolism and inflammatory environment. Especially in macrophage-derived foam cells, which has become a potential strategy for the treatment of AS. In this study, we prepared the conjugate (DB) of dextran (DEX) and bovine serum albumin (BSA). The DB was used as the emulsifier to prepare nanoemulsion loaded with upconversion nanoparticles (UCNPs) and chlorin e6 (Ce6) (UCNPs-Ce6@DB). The DEX modified on the surface of the nanoemulsion can recognise and bind to the scavenger receptor class A (SR-A) highly expressed on macrophages and promote the uptake of macrophage-derived foam cells in AS plates through SR-A-mediated endocytosis. In addition, UCNPs-Ce6@DB-mediated PDT enhanced ROS generation and induced autophagy in macrophage-derived foam cells, enhanced the expression of ABCA1, a protein closely related to cholesterol efflux, and inhibited the secretion of pro-inflammatory cytokines. Ultimately, UCNPs-Ce6@DB was shown to inhibit plaque formation in mouse models of AS. In conclusion, UCNPs-Ce6@DB offers a promising treatment for AS.
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INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH
·
2023
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IF 4.2
Xinbao Zhang,Guanghui Zhang,Xiangkun Zhou,Zhiqun Wang,Yi Liu,Jie Zhu,Chunshan Song,Xinwen Guo
Interest in identifying the structure of the catalysts in the reaction atmosphere has grown, but it remains challenging, especially when the changes only occur on the surface. Herein, we track the reaction-induced structural changes of ZnO/ZrO2 and their consequent effects on the activity and selectivity of CO2 hydrogenation. Utilizing a combination of in situ infrared and controlled experiments, we meticulously investigate the dynamic changes of the catalyst’s surface structure with time on stream. The reaction-driven growth of ZnOx clusters is correlated with the enhanced CO2 hydrogenation activity of ZnO/ZrO2. Furthermore, in situ infrared results show that the aggregation of ZnOx clusters promotes hydrogen activation, thereby facilitating the synthesis of methanol. The modification of the interfacial sites confirms the significance of the ZnO–ZrO2 interface as the main site for CO formation, while the surface of ZnOx clusters predominantly contributes to methanol synthesis at low zinc loading. These findings advance our comprehension of the structure–activity relationship of zinc-based catalysts for CO2 hydrogenation.
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ChemistrySelect
·
2023
·Vol. 8
·期 45
·e202303449
·
IF 2.1
Hang Yin,Chongchao Zhang,Xiao Bai,Ziyin Yang,Zhe Liu
Graphical The doping of B induced the formation of ultrafine Co nanoparticles and realized highly sensitivity non-enzymatic glucose sensing. Doping is one of the effective methods to improve the performance of sensors. Here, we reported that B-doping can induce the formation of ultrafine Co nanoparticles for realizing highly sensitivity non-enzymatic glucose sensing. Co/NC and Co/BNC were prepared by ion exchange and pyrolysis methods. It is interesting to find that B doping can achieve spatial isolation and prevent metal aggregation during MOF pyrolysis. This made the particle size of Co nanoparticles smaller and more uniform, which enriches the active site and thus improves the sensing performance for glucose. The electrochemical results indicate that Co/BNC exhibits strong electrocatalytic activity toward glucose oxidation and the non-enzymatic sensor based on Co/BNC shows excellent performance for glucose analysis with a wide linear range of 0.4 μM–0.522 mM, a high sensitivity of 1064.3 μA mM −1 cm −2 and a low detection limit of 0.08 μM (S/N=3). Therefore, this study demonstrated Co/BNC as a promising glucose sensing material and also provided a novel strategy for improving electrochemical sensing performance through doping.
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Journal of Energy Chemistry
·
2023
·
IF 13.1
Weiting Gao,Xuelang Gao,Qiugen Zhang,Aimei Zhu,Qinglin Liu
Building well-developed ion-conductive highways is highly desirable for anion exchange membranes (AEMs). Grafting side chain is a highly effective approach for constructing a well-defined phase-separated morphological structure and forming unblocked ion pathways in AEMs for fast ion transport. Fluorination of side chains can further enhance phase separation due to the superhydrophobic nature of fluorine groups. However, their electronic effect on the alkaline stability of side chains and membranes is rarely reported. Here, fluorine-containing and fluorine-free side chains are introduced into the polyaromatic backbone in proper configuration to investigate the impact of the fluorine terminal group on the stability of the side chains and membrane properties. The poly(binaphthyl-co-p-terphenyl piperidinium) AEM (QBNpTP) has the highest molecular weight and most dimensional stability due to its favorable backbone arrangement among ortho- and meta-terphenyl based AEMs. Importantly, by introducing both a fluorinated piperidinium side chain and a hexane chain into the p-terphenyl-based backbone, the prepared AEM (QBNpTP-QFC) presents an enhanced conductivity (150.6 mS cm −1 ) and a constrained swelling at 80 °C. The electronic effect of fluorinated side chains is contemplated by experiments and simulations. The results demonstrate that the presence of strong electro-withdrawing fluorine groups weakens the electronic cloud of adjacent C atoms, increasing OH − attack on the C atom and improving the stability of piperidinium cations. Hence QBNpTP-QFC possesses a robust alkaline stability at 80 °C (95.3% conductivity retention after testing in 2 M NaOH for 2160 h). An excellent peak power density of 1.44 W cm −2 and a remarkable durability at 80 °C (4.5% voltage loss after 100 h) can be observed.
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JOURNAL OF ALLOYS AND COMPOUNDS
·
2026
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IF 6.7
Yigui Sun,Chunxiao Lu,Fen Zhao,Shuai Li,Ye Zhao,Xiangyu Yin,Yong Li,Qiwei Zhang
Eu/La co-doped BaMgSiO 4 photochromic ceramics were fabricated via tape casting, which effectively improves the mechanical properties of the material. • The obtained ceramics exhibit high photochromic contrast, stable thermal fading performance and efficient reversible luminescence modulation. • Oxygen vacancies generated by Eu/La co-doping trigger dual-mode photoresponse, enabling multifunctional optical and flexible wearable applications. Inorganic photochromic materials with reversible photoresponse are widely applied in optical anti-counterfeiting, information storage and visual sensing. However, it remains a critical challenge to simultaneously achieve high strength and multimodal photoresponse in a single photochromic system. In this study, Eu 2+ /La 3+ co-doped BaMgSiO 4 photochromic ceramics are fabricated by tape casting. La 3+ doping effectively refines grains and improves density, leading to enhanced mechanical properties with Vickers hardness of 6.62 GPa and fracture toughness of 3.52 MPa·m 1/2 . Optical measurements confirm that the ceramic achieves a photochromic contrast of 80.2% (reflectance at 525 nm) and luminescence modulation of 34.4% (Eu 2+ emission at 443 nm) upon 365 nm irradiation for 4 s, with favorable linear thermal fading behavior. This work develops mechanically enhanced ceramics with dual-mode photochromic response, offering novel technical strategies and theoretical insights for advancing inorganic photochromic ceramics toward practical applications.
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INTERNATIONAL JOURNAL OF PHARMACEUTICS
·
2023
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IF 5.8
Chang Liu,Xiaojun Zhang,Huiying Yang,Meijun Zhao,Yanhong Liu,Risheng Zhao,Ziqing Li,Meng Sun
Ischemic heart disease (IHD) is a cardiac disorder in which myocardial damage occurs as a result of myocardial ischemia and hypoxia. Evidence suggests that oxidative stress and inflammatory responses are critical in the development of myocardial ischemia. Therefore, the combination of antioxidant and anti-inflammatory applications is an effective strategy to combat ischemic heart disease. In this paper, polyethylene glycol (PEG)-modified cationic liposomes were used as carriers to deliver apigenin (Apn) with small interfering RNA (siRNA) targeting the receptor for glycosylation end products (RAGE) (siRAGE) into cardiomyocytes to prevent myocardial ischemic injury through antioxidant and anti-inflammatory effects. Our results showed that we successfully prepared cationic PEG liposomes loaded with Apn and siRAGE (P-CLP-A/R) with normal appearance and morphology, particle size and Zeta potential, and good encapsulation rate, drug loading and in vitro release degree. In vitro , P-CLP-A/R was able to prevent oxidative stress injury in H9C2 cells, downregulate the expression of RAGE, reduce the secretion of cellular inflammatory factors and inhibit apoptosis through the RAGE/NF-κB pathway; In vivo , P-CLP-A/R was able to prevent arrhythmia and myocardial pathological injury, and reduce apoptosis and the area of necrotic myocardium in rats. In conclusion, P-CLP-A/R has a protective effect on myocardial ischemic injury and is expected to be a potential drug for the prevention of ischemic heart disease in the future.
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高影响因子
RSC Advances
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2023
·Vol. 13
·期 45
·31785-31794
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IF 3.9
Yi Yu,Kai Shao,Chonghui Niu,Mingjie Dan,Yingying Wang,Xiourong Zhu,Xianke Zhang,Yeqing Wang
In recent years, more and more attention has been paid to optical temperature sensing, and how to improve its accuracy is the most important issue. Herein, a new temperature sensing material, SrGd2Al2O7:Bi3+,Mn4+, based on fluorescence intensity ratio was designed in this work. It has both blue-purple and red luminescence under 300 nm excitation, and the dual-emitting centers with distinct colors, the different thermal sensitivities of Bi3+ and Mn4+, and the energy transfer between Bi3+ and Mn4+ give it excellent signal resolution and accurate temperature detection. The Sa of SrGd2Al2O7:0.04Bi3+,0.003Mn4+ phosphor reaches a maximum value of 8.573% K−1 at 473 K, and the corresponding Sr is 1.927% K−1, both of which are significantly better than those of most other reported optical temperature sensing materials. Taking all the results into account, the SrGd2Al2O7:0.04Bi3+,0.003Mn4+ phosphor can be regarded as a prominent FIR-type temperature sensing material.
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JOURNAL OF CHEMICAL THERMODYNAMICS
·
2023
·
IF 2.6
Qiang Gao,Ali Farajtabar
The shake-flask technique was used to test the solubility of glyburide in mixtures of acetone + water and ethyl acetate + methanol/ethanol/isopropanol under 101.0 kPa. For a fixed temperature, the glyburide solubility positively increased with the mass fraction of acetone in the acetone + water mixture, and reached a maximum value of 8.805 × 10 −6 at 298.15 K. The solubility magnitudes reach their peak when the mass fraction of ethyl acetate in solutions containing ethyl acetate plus methanol/ethanol/isopropanol is approximately 0.3, which correspond to 5.703 × 10 −4 , 5.235 × 10 −4 and 4.307 × 10 −4 , respectively, at 298.15 K. Two models-the Jouyban-Acree and modified van't Hoff-Jouyban-Acree were employed to correlate the solutility and produced the biggest relative average deviation of 7.78 %. The local composition (solvents) around the drug molecule was investigated at 298.15 K using an inverse Kirkwood-Buff integrals. The positive preferred solvation parameters of glyburide were observed in the medium and rich compositions of methanol/ n -propanol/isopropanol/acetonitrile/PG/NMP (taken from published works)/acetone, signifying that glyburide was preferentially solvated by these solvents; while they had negative magnitudes in ethyl acetate + methanol/ethanol/isopropanol systems throughout the whole ethyl acetate compositions. The solubility of glyburide in the ten solutions was properly described by an extended Hildebrand solubility parameter approach, with relative average errors of no more than 5.32 %. In addition, the electrostatic characteristics of the basicity/acidity of glyburide molecule were highlighted with the help of quantitative study of molecular surface. Because of their lowest (-158.0 kJˑmol −1 to −136.6 kJˑmol −1 ) and largest (156.6 kJˑmol −1 to 182.8 kJˑmol −1 ) global electrostatic potentials, the > C = O and > NH groups are the main targets of electrophilic and nucleophilic assault. Visual examination of the weak interactions between glyburide and the neat solvents (methanol, ethanol, isopropanol, acetone, ethyl acetate, and water) was done using the Hirshfeld partition analysis-based independent gradient model.
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JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY
·
2023
·
IF 6.1
Renjie Xie,Jianbin Lu,Jian Wang
The detection of dissolved gases in the oil of oil-immersed transformers is essential to evaluate the operating status of oil-immersed transformers. In this study, a CuO/TiO 2 /N-MWCNTs composites-based sensor was fabricated by hydrothermal method for the detection of dissolved CO gas in oil. The introduction of N-MWCNTs with high specific surface area, high electrical conductivity and multiple adsorption sites effectively improved the response value and response/recovery performance for CO. The response can reach 4.33 at a CO concentration of 50 ppm, which is 1.74 times higher than that of the CuO/TiO 2 sensor. In addition, the prepared sensor presents a fast response/recovery time (230 s/60 s) to CO, and has excellent selectivity and long-term stability. Finally, a multi-concentration CO alarm system was constructed through a reasonable circuit design. It is shown that the CuO/TiO 2 /N-MWCNTs-based sensor can achieve high-precision CO detection, which can provide a new idea for the detection of dissolved CO gas in the oil of oil-immersed transformers.
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SENSORS AND ACTUATORS B-CHEMICAL
·
2023
·
IF 8.4
Jiajing Xu,Weiqiang Yang,Jiancong Ni,Qingxiang Wang,Zhenyu Lin
Electrochemiluminescence (ECL) arises from the collisional annihilation between the electro-excited luminophore and co-reactant. Most ECL-based bioassays require extensive free co-reactants that collide with luminophores randomly. Herein, the N,N-dimethylaniline (DMA) group was electro-grafted on the ITO electrode surface as the bottom co-reactant layer, and the vertically ordered mesoporous silica film (VMSF) was prepared as the upper layer to regulate the accessibility of Ru(bpy) 3 2+ . Thus, the dual-layer functionalized VMSF/N-ITO was newly built for the controllable ECL study. Relevant conditions, including the DMA electro-grafting, VMSF thickness, buffer concentration and pH value, were discussed to improve the ECL efficiency. Based on the VMSF/N-ITO platform, a homogeneous ECL bioassay was developed for miRNA-21 detection. The target nucleotide sequence induced the hybridization chain reaction (HCR) of probes H1 and H2 to absorb free Ru(bpy) 3 2+ as much as possible. Residual Ru(bpy) 3 2+ permeated the VMSF nanochannels to collide with the DMA co-reactant in producing an ECL response. There was a linear relationship between ∆ECL intensity and logarithmic concentration of miRNA-21 in the 1 fM ∼ 100 pM range, and the detection limit was 0.25 fM. The developed approach was probes immobilization-free, highly sensitive, and anti-interference, opening a new avenue for ECL-based bioassays.
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APPLIED CATALYSIS B-ENVIRONMENTAL
·
2023
·
IF 22.1
Can Fang,Xiangmei Tang,Qingfeng Yi
Exploring efficient non-precious metal oxygen electrocatalysts for oxygen reduction/evolution reactions (ORR/OER) is of great importance in electrochemical energy conversion devices like metal-air battery. Among them, carbon-based composites derived from metal-organic framework (MOF) exhibit excellent catalytic performance in ORR/OER. In this paper, Co-MOF-67 was firstly prepared, and then mixed with FeCl 3 ·6 H 2 O and dicyandiamide, followed by a one-step pyrolysis to obtain bamboo-like nitrogen-doped carbon nanotubes . For the samples, Fe and Co nanoparticles were encapsulated in the front end of the carbon nanotubes and the presence of new (n)-diamond carbon was unexpectedly found. The obtained catalyst (FeCo@CNTs-60) has an onset potential of 1.04 V for ORR in alkaline solution, which is close to the commercial Pt/C (40 wt% Pt) of 1.05 V. The onset potential of 1.02 V in quasi-neutral solution exceeds that of Pt/C of 0.99 V. In addition, FeCo@CNTs-60 exhibited a low potential difference of 0.81 V between OER and ORR potentials. The alkaline zinc-air batteries, fabricated with the sample as the electrocatalyst of air electrode, exhibit higher peak power density and stability than Pt/C, while the rechargeable batteries present superior cycling discharge/charge stability at 5 mA·cm −2 and 10 mA·cm −2 . In particular, the battery with FeCo@CNTs-60 was conducted for continuous over 1300 h of ultra long-term cycle charging / discharging test at a current density of 5 mA·cm −2 , and it reveals excellent stability with high voltage efficiency and also presents superior cycle charging / discharging stability after replacing the Zn plates and electrolyte.
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