ANALYTICA CHIMICA ACTA
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2026
·
IF 6.1
Guobin Huang,Zhonghua Pan,Qilong Wang,Qingqing Liang,Jiayi Wu,Yanmei Zhou,Tianju Chen,Wangchuan Xiao
Background Phthalate acid esters (PAEs) are endocrine-disrupting contaminants that require reliable trace-level monitoring in environmental waters. Magnetic dispersive solid-phase extraction (MDSPE) offers a green sample-preparation approach, but its performance is often constrained by the limited adsorption capacity, poor structural integrity, limited reusability, and high material cost of existing sorbents. Developing a stable, magnetically responsive, and high-affinity nanocomposite to overcome these limitations remains a critical challenge. Results A novel ternary magnetic MWCNTs@Fe 3 O 4 @MIL-101(Fe) nanocomposite was successfully synthesized via a facile hydrothermal strategy, where multi-walled carbon nanotubes (MWCNTs) serve as a conductive scaffold intertwining Fe 3 O 4 nanoparticles and MIL-101(Fe) crystals. This unique architecture endows the sorbent with high saturation magnetization (58.9 emu/g) for rapid separation, a large specific surface area (1127.28 m 2 /g), and abundant π-electron-rich sites for enhanced adsorption. Under optimized MDSPE conditions coupled with gas chromatography-flame ionization detection (GC-FID), the method achieved wide linear ranges (0.05-2500 μg/L), ultra-low limits of detection (0.005-0.05 μg/L), and satisfactory absolute recoveries (89.5%-110.6%) in real environmental water samples. The sorbent exhibited good reusability (≥90% after five cycles) and excellent precision (RSDs <9.0%). Greenness assessment using the AGREE metric yielded a score of 0.65, reflecting a moderate-to-high level of environmental sustainability. Significance and novelty This work presents a novel “MWCNT-bridged” strategy that successfully integrates magnetic responsiveness, high porosity, and π-π interaction sites into a single, stable sorbent, resolving the common trade-off between functionality and recoverability in magnetic MOF composites. The rationally designed nanocomposite provides a robust, highly sensitive, and environmentally sustainable platform for monitoring trace PAEs in complex aqueous matrices, advancing the development of functional materials for green analytical chemistry.
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高影响因子
ANALYTICAL SCIENCES
·
2026
·
IF 2
Lu Chang,Ma Wei-bo,Wang Jun,Duan Ding-ding,Chen Zhi-zhou,Ma Yan-li
Accurate quantification of pesticide residues is critical to ensure the quality and safety of Rhizoma Polygonati , a well-recognized medicine-food homologous herb widely applied in functional food development. Strong matrix interference in gas chromatography-tandem mass spectrometry (GC-MS) detection and notable quantitative bias are frequently induced by the abundant pigments, polysaccharides, saponins and endogenous components in the herbal matrix. Conventional PSA and C 18 adsorbents in standard QuEChERS protocols exhibit restricted purification capacity for this complex matrix, while most documented magnetic carbon-based adsorbents demand tedious pre-synthesis procedures that may block the active adsorption sites of nanomaterials. A modified QuEChERS-GC-MS method coupled with dynamic in-situ assembly strategy was established for 12 pesticide residues in Rhizoma Polygonati . Without pre-synthesis of any composites, in-situ functional synergy between NH 2 -SWCNTs and magnetic Fe 3 O 4 nanoparticles was achieved during the dispersive solid-phase extraction (d-SPE) step. Superior purification performance to conventional adsorbents was obtained by this system, with the matrix effect range of target pesticides narrowed from -31.4%−64.3% to -25.3%−36.7%. Favorable linearity ( R ≥ 0.9990), acceptable spiked recoveries (86.2%–106.5%) and stable precision (RSD ≤ 15.20%) were validated through systematic method validation, providing a feasible and robust analytical protocol for pesticide residue monitoring in Rhizoma Polygonati and other complex herbal matrices. Graphical abstract
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Frontiers in Bioengineering and Biotechnology
·
2023
·
IF 5.7
Sun Xiaolong,Hu Jiahuan,Wang Yifeng,Luo Xi,Huang He,Fu Yongqian
The main challenges in bio-catalysis of d-phenyllactic acid (D-PLA) are poor tolerance of lactate dehydrogenase (LDH) to harsh environmental conditions and inability to recycle the catalyst. A novel magnetic framework composite was prepared as solid support for the immobilization of enzymes via one-pot encapsulation in this study. LDH/MNPs@MAF-7 was synthesized by the one-pot encapsulation of both LDH and magnetic nanoparticles (MNPs) in MAF-7. The LDH/MNPs@MAF-7 showed stable biological activity for the efficient biosynthesis of D-PLA. The structure and morphology of LDH/MNPs@MAF-7 were systematically characterized by SEM, FT-IR, XRD, VSM, XPS, TGA and N2 sorption. These indicated that LDH/MNPs@MAF-7 was successfully synthesized, exhibiting enhanced resistance to acid and alkali, temperature and organic solvents. Furthermore, the bio-catalyst could be separated easily using a magnet, and the reusability was once considerably expanded with 80% of enzyme activity last after eight rounds of recycling. Therefore, LDH/MNPs@MAF-7 could be used as a potential biocatalyst for the biosynthesis of D-PLA due to its good stability and recovery properties.
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NEW JOURNAL OF CHEMISTRY
·
2022
·Vol. 46
·期 20
·9658-9665
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IF 3.925
Bo Song,Mengyan Li,Junyu Ren,Qi Liu,Xinyi Wen,Wenzhu Zhang,Jingli Yuan
The combination of complementary optical imaging and magnetic resonance imaging (MRI) techniques evolved to provide an even more powerful tool to simultaneously obtain both molecular information and anatomical information as well as to dramatically improve the accuracy of detection. Herein, we report a new tumor-targetable bimodal time-gated luminescence (TGL)–MRI nanoprobe for tracing cancer cells in vitro and in vivo. The nanoprobe was constructed by coating superparamagnetic Fe3O4 nanoparticles with functional silica shells that encapsulated luminescent Eu3+ complexes and were decorated with tumor-targeting molecules, folic acid (FA), on the surface. The fabricated nanoprobe possesses strong long-lived luminescence and excellent magnetic properties, as well as outstanding stability, biocompatibility and dispersibility in water. Furthermore, the nanoprobe can specifically bind to FA receptor-overexpressed cancer cells, allowing it to be accumulated in these cells. These features enable the nanoprobe to be successfully used for TGL imaging of cultured cancer cells and bimodal TGL–MR imaging of tumors in tumor-bearing mice with high sensitivity and accuracy. The research outcomes will contribute to the development of a new bimodal optical/MR imaging nanoprobe for the tracing and precise detection of cancerous cells.
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INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
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2022
·Vol. 23
·期 11
·5900
·
IF 6.208
Zhangzhen Cai,Qi Liu,Haoxin Li,Jingyi Wang,Guoyu Tai,Fan Wang,Jiangang Han,Yongli Zhu,Guangyu Wu
Recently, metal–organic frameworks (MOFs), which are porous inorganic–organic hybrid materials consisting of metal ions (clusters or secondary building units) and organic ligands through coordination bonds, have attracted wide attention because of their high surface area, huge ordered porosity, uniform structural cavities, and excellent thermal/chemical stability. In this work, durian shell biomass carbon fiber and Fe3O4functionalized metal–organic framework composite material (durian shell fiber-Fe3O4-MOF, DFM) was synthesized and employed for the adsorption removal of methylene blue (MB) from wastewater. The morphology, structure, and chemical elements of the DFM material were characterized by scanning electron microscope (SEM), X-ray diffraction (XRD), transmission electron microscope (TEM), and X-ray photoelectron spectroscope (XPS) techniques. Adsorption conditions such as pH, adsorption time, and temperature were optimized. The adsorption isotherm and kinetics results show that the adsorption process of DFM material to MB is more in line with the Freundlich model and pseudo-second-order kinetic model. Using these models, the maximum adsorption capacity of 53.31 mg/g was obtained by calculation. In addition, DFM material could be easily reused through an external magnet and the removal rate of MB was still 80% after five adsorption cycles. The obtained results show that DFM composite material, as an economical, environmentally friendly, recyclable new adsorbent, can simply and effectively remove MB from wastewater.Keywords:biomass fibers;durian shell;magnetic composite;adsorption
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Frontiers in Public Health
·
2022
·
IF 6.461
Shi Xuening,Sun Hongbin,Li Hang,Wei Shengnan,Jin Jin,Zhao Chao,Wang Juan,Li Hui
Immunomagnetic separation based on Fe3O4 magnetic nanoparticles (MNPs) has been widely performed in sample pretreatment. The oriented conjugation strategy can achieve a better capture effect than the N-(3-dimethylamlnopropyl)-N'-ethylcarbodiimide hydrochloride (EDC) /N-hydroxysuccinimide (NHS) method. However, immunoglobulin yolk (IgY) cannot be oriented through an SPA strategy like immunoglobulin G (IgG). In this article, an oriented conjugation nanoprobe was prepared for the enrichment of bacteria based on pH adjusting. The main factors affecting the enrichment efficiency were studied, such as the pH of the buffer system, the concentration of IgY, the concentration of nanoprobe, and the enrichment time. Under the optimal conditions, the enrichment efficiency toward target bacteria could reach 92.8%. Combined with PCR, the limit of detection (LOD) was found to be 103 CFU/ml, which was lower than the PCR only. In conclusion, we provided a new protocol for the oriented conjugation of IgY and high sensitivity detection with simple pretreatment.
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Small
·
2021
·Vol. 18
·期 9
·2105465
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IF 13.281
Jiayu Xiao,Luo Hai,Yaoyao Li,Huan Li,Minhui Gong,Zefeng Wang,Zifeng Tang,Le Deng,Dinggeng He
Nanozyme-based chemodynamic therapy (CDT) for fighting bacterial infections faces several major obstacles including low hydrogen peroxide (H 2 O 2 ) level, over-expressed glutathione (GSH) in infected sites, and inevitable damage to healthy tissue with abundant nonlocalized nanozymes. Herein, a smart ultrasmall Fe 3 O 4 -decorated polydopamine (PDA/Fe 3 O 4 ) hybrid nanozyme is demonstrated that continuously converts oxygen into highly toxic hydroxyl radical (•OH) via GSH-depleted cascade redox reactions for CDT-mediated bacterial elimination and intensive wound disinfection. In this system, photonic hyperthermia of PDA/Fe 3 O 4 nanozymes can not only directly damage bacteria, but also improve the horseradish peroxidase-like activity of Fe 3 O 4 decorated for CDT. Surprisingly, through photothermal-enhanced cascade catalytic reactions, PDA/Fe 3 O 4 nanozymes can consume endogenous GSH for disrupting cellular redox homeostasis and simultaneously provide abundant H 2 O 2 for improving •OH generation, ultimately enhancing the antibacterial performance of CDT. Such PDA/Fe 3 O 4 can bind with bacterial cells, and reveals excellent antibacterial property against both Staphylococcus aureus and Escherichia coli . Most interestingly, PDA/Fe 3 O 4 nanozymes can be strongly retained in infected sites by an external magnet for localized long-term in vivo CDT and show minimal toxicity to healthy tissues and organs. This work presents an effective strategy to magnetically retain the therapeutic nanozymes in infected sites for highly efficient CDT with good biosafety.
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Nanomaterials
·
2021
·Vol. 11
·期 9
·2177
·
IF 5.076
Easar Alam,Qiyan Feng,Hong Yang,Jiaxi Fan,Sameena Mumtaz,Farida Begum
In this study, iron oxide (Fe3O4) was coated with ZrO2, and doped with three rare earth elements((Y/La/Ce), and a multi-staged rare earth doped zirconia adsorbent was prepared by using uniform design U14, Response Surface methodology, and orthogonal design, to remove As3+and As5+from the aqueous solution. Based on the results of TEM, EDS, XRD, FTIR, and N2-adsorption desorption test, the best molar ratio of Fe3O4:TMAOH:Zirconium butoxide:Y:La:Ce was selected as 1:12:11:1:0.02:0.08. The specific surface area and porosity was 263 m2/g, and 0.156 cm3/g, respectively. The isothermal curves and fitting equation parameters show that Langmuir model, and Redlich Peterson model fitted well. As per calculations of the Langmuir model, the highest adsorption capacities for As3+and As5+ions were recorded as 68.33 mg/g, 84.23 mg/g, respectively. The fitting curves and equations of the kinetic models favors the quasi second order kinetic model. Material regeneration was very effective, and even in the last cycle the regeneration capacities of both As3+and As5+were 75.15%, and 77.59%, respectively. Adsorption and regeneration results suggest that adsorbent has easy synthesis method, and reusable, so it can be used as a potential adsorbent for the removal of arsenic from aqueous solution.Keywords:magnetic Fe3O4;uniform design;surface response methodology;multi-staged doping;arsenic (III & V) removal
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Separations
·
2021
·Vol. 8
·期 11
·196
·
IF 2.777
Qing Han,Xiaoxiao Wu,Yi Cao,Hua Zhang,Yuqin Zhao,Xuejun Kang,Huaiyuan Zhu
A novel magnetic solid phase extraction based on mercaptophenylboronic acid (MPBA)-functionalized Fe3O4-NH2@Au nanomaterial (Fe3O4-NH2@Au-MPBA) was developed for selective separation and enrichment of catecholamines (including dopamine, norepinephrine and adrenaline). Fe3O4-NH2@Au-MPBA nanoparticles were achieved by self-assembly-anchoring MPBA molecules on the surface of Fe3O4-NH2@Au nanocomposites, which were synthesized via a facial ultrasonic auxiliary in situ reduction process. The interaction between cis-diol from catecholamines and boronic acid was reversible and could be flexibly controlled by adjusting pH value. The catecholamines could be quickly adsorbed by Fe3O4-NH2@Au-MPBA in weak alkaline solution (pH 8.0–9.0) and subsequently released in acid solution (pH 1.0–2.0). The process of adsorption and dissociation was very fast. Furthermore, the three catecholamines could be detected in urine from children by high performance liquid chromatography (HPLC) with electrochemical detector. Under optimal conditions, norepinephrine (NE), epinephrine (EP) and dopamine (DA) were separated very well from internal standard and exhibited a good linearity in the range of 2.5–500.0 ng mL−1, with correlation coefficients of r2> 0.9907. Limits of detection (LOD) (signal to noise = 3) were 0.39, 0.27 and 0.60 ng mL−1for NE, EP and DA, respectively. Recoveries for the spiked catecholamines were in the range of 85.4–105.2% with the relative standard deviation (RSD) < 11.5%.Keywords:Fe3O4-NH2@Au;magnetic solid phase extraction;catecholamines;HPLC;electrochemical detection;urine
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CATALYSIS LETTERS
·
2021
·Vol. 152
·期 4
·1076-1085
·
IF 3.186
Wang Gongshu,Chen Zhangpei,Chen Tian,Lv Kexin,Reheman Aikebaier,Hu Jianshe
A magnetic nanostructured catalyst (Fe 3 O 4 @SiO 2 -Amp-Rh) modified with 2-(aminomethyl)phenols (Amp) was designed and prepared, which is used to catalyze the reduction of aromatic nitro compounds into corresponding amines and the degradation of dyes. The 2-aminomethylphenol motif plays a vital role in the immobilization of rhodium nanoparticles to offer extraordinary stability, which has been characterized by using various techniques, including transmission electron microscopy (TEM), thermal gravimetric analyzer (TGA), X-Ray Diffraction (XRD), and X-ray photoelectron spectroscopy (XPS). A variety of nitroaromatic derivatives have been reduced to the corresponding anilines in water with up to yields of 99% within 1 h at room temperature. In addition, the catalyst system is effective in catalyzing the reduction of toxic pollutant 4-nitrophenol and the degradation of MO, MB and RhB dyes. Importantly, this catalyst Fe 3 O 4 @SiO 2 -Amp-Rh can be easily recovered by an external magnetic field because of the presence of magnetic core of Fe 3 O 4 , and the activity of Fe 3 O 4 @SiO 2 -Amp-Rh does not decrease significantly after 7 times’ recycling, which indicates that the catalyst performed high reactivity as well as stability. Graphical abstract
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CHEMOSPHERE
·
2020
·
IF 5.778
Zhiguo Lin,Jing Chen
In order to facilitate recovery and enhance phosphate adsorption capacity of lanthanum (La)-based materials, magnetic Fe 3 O 4 @MgAl-LDH@La(OH) 3 (MMAL) composites with a hierarchical core-shell structure were synthesized. In the preparation process, citric acid played a vital role in the morphology control of La(OH) 3 , deciding the La content and phosphate adsorption capacity of materials. MMAL composites with a citric acid-to-La molar ratio of 0.375 (MMAL-0.375) exhibited a high adsorption capacity of 66.5 mg P/g, fast adsorption kinetics of 30 min, widely applicable pH range of 4.0–10.0, outstanding selective adsorption performance, and superior reusability in batch adsorption experiments. Moreover, the phosphate in the desorption solution could be concentrated by repeated use of desorption solution and recovered by using CaCl 2 . When the obtained composites were used for the sedimentary phosphorus sequestration and recovery, the results showed that the addition of MMAL-0.375 effectively reduced the concentration of soluble reactive phosphorus (SRP) in the overlying water. Accompanied by an evident increase in HCl-extractable phosphorus (HCl–P), mobile phosphorus (P mob ) in sediments was effectively reduced. This work indicates that the MMAL-0.375 composites can serve as an effective tool for the removal of phosphate from wastewater and the control of sedimentary phosphorus.
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MICROCHEMICAL JOURNAL
·
2019
·
IF 3.206
Xiaoli Guo,Yanting Li,Bo Zhang,Lingling Yang,Xin Di,Xin Di
Herein, magnetic nanoparticle coated with zinc-aluminum layered double hydroxide was successfully synthesized and characterized. The nanocomposite was used as an effective adsorbent to extract three phenoxy acid herbicides in water samples prior to high performance liquid chromatography-ultraviolet detection. An interesting characteristic of this sorbent is that it dissolves under acidic solution (pH < 4). As a result, the elution step was unnecessary, and no organic solvent was used in whole extraction process. Influential extraction factors such as pH of solution, amount of sorbent, type and volume of acidic solution and vortex time were optimized. The method displays low limits of detection (0.1−0.2 ng mL −1 ), good linearity (0.5−200 ng mL −1 ), acceptable precision (relative standard deviations were less than 9.3%) and accuracy (98.9–106.1%). Therefore, the method is sensitive, fast, eco-friendly, and suitable for determination of phenoxy acid herbicides in water samples.
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