REFRACTORIES AND INDUSTRIAL CERAMICS
·
2023
·
IF 0.5
Ding Donghai,Guan Yue,Xiao Guoqing,Mao Zhaoyuan,Shi Xiaoqi,Gao Kaiqiang,Chong Xiaochuan,Luo Jiyuan,Lei Changkun
The alumina ceramics with high compressive strength were prepared by pressureless sintering, and the kaolinite and calcium carbonate were added as Al 2 O 3 –SiO 2 –CaO sintering aids. The effects of sintering temperature on the volume shrinkage, bulk density, water absorption and compressive strength of the alumina ceramics were studied. The phase composition, crystal cell parameters, average grain size and microstructure of the ceramic were analyzed by XRD, SEM and EDS. The results show that the lattice tends to packed with the increase of sintering temperature. The bonding between grains is the most compact after sintering at 1700°C. The volume shrinkage increases with the increase of sintering temperature. The water absorption of alumina ceramics after sintering at 1700°C reaches the minimum value of 0.06%. The bulk density and compressive strength increase first and then decrease with the increase of sintering temperature. At 1700°C, optimized mechanical properties of alumina ceramics is obtained, with a bulk density of 3.80 g/cm 3 and a compressive strength of 1323 MPa.
✓ 已验证
DOI
高影响因子
MICROCHIMICA ACTA
·
2021
·Vol. 188
·期 6
·1-11
·
IF 5.833
Ma Mingxuan,Zhang Jian,Li Peipei,Du Yingxiang,Gan Jie,Yang Jiangxia,Zhang Liu
Metal-organic framework (UiO-66-NH 2 )-incorporated organic polymer monolith was prepared by thermal polymerization. By virtue of the superior physical and chemical properties, the UiO-66-NH 2 -modified organic monolith was then functionalized by chiral selector cellulase via the condensation reaction between the primary amino groups and aldehyde groups. The synthesized materials were characterized by Fourier transform infrared spectroscopy, high-resolution transmission electron microscopy, scanning electron microscopy, X-ray photoelectron spectrometry, thermogravimetric analysis, and nitrogen sorption isotherm. The cellulase@poly(glycidyl methacrylate-UiO-66-NH 2 -ethylene glycol dimethacrylate) (cellulase@poly(GMA-UiO-66-NH 2 -EDMA)) monolith was applied to enantiomerically separate the basic racemic forms of metoprolol, atenolol, esmolol, bisoprolol, and propranolol. In contrast to the cellulase@poly(GMA-co-EDMA) monolith without UiO-66-NH 2 , the cellulase@poly(GMA-UiO-66-NH 2 -EDMA) monolith reveals significantly improved enantiodiscrimination performance for metoprolol (Rs: 0 → 1.67), atenolol (Rs: 0 → 1.50), esmolol (Rs: 0 → 1.52), bisoprolol (Rs: 0 → 0.36), and propranolol (Rs: 0 → 0.44). The immobilization pH of cellulase, buffer pH, UiO-66-NH 2 concentration, and the proportion of organic modifier were evaluated in detail with enantiomerically separating chiral molecules. The intra-day, inter-day, column-to-column, and inter-batch precision have been discussed, the result was preferable, and the relative standard deviation (RSD) of separation parameters was <4.3%. Graphical abstract
Schematic representation of the preparation of a UiO-66-NH 2 -modified organic polymer monolith for enantioseparating five racemic β-blockers. UiO-66-NH 2 was synthesized and converted into a monolith as the stationary phase. Then, the modified monolith containing cellulase as the chiral selector was applied in a capillary electrochromatography system for enantioseparating chiral drugs.
✓ 已验证
DOI
PubMed
高影响因子
MICROCHIMICA ACTA
·
2020
·Vol. 187
·期 2
·1-9
·
IF 6.232
Yang Dezhi,Wang Yingdong,Li Hong,Yang Yaling
A sensitive method based on the use of green deep eutectic solvents (DESs) was designed for the determination of bisphenol-A, bisphenol-AF, tetrabromobisphenol-A and 4-tert.-octylphenol followed by HPLC. This method takes advantage of magnetic solid-phase extraction purification and acid-base induced DES liquid-liquid microextraction. The Mg(II)-Al(III) layered double hydroxide-coated magnetic nanoparticles were selected to purify samples. The DESs were systematically prepared by a range of medium-chain saturated fatty acids (C 8 -C 12 ) and D,L-menthol. The melting point and the extraction efficiency of phenolic compounds were adjusted by changing the carbon chain length of fatty acid in suitable proportions. Acid-base induction significantly improves the extraction efficiency. The method has lower limits of detection ranging from 6 to 11 ng L −1 , good linearity (0.05–500 μg L −1 ) and high enrichment factors (86–91). The method was successfully applied for the determination of four phenolic compounds in beverage samples. The recoveries ranged from 84.4 to 101.3%.
Schematic representation of the extraction of four phenolic compounds by medium chain (C 8 -C 12 ) fatty acid-based eutectic solvent (DES) through acid-base-induction.
✓ 已验证
DOI
PubMed
高影响因子
MICROCHIMICA ACTA
·
2017
·Vol. 184
·期 9
·3565-3572
·
IF 4.58
Li Mingshi,Wang Yanying,Ye Xiaoxue,Wang Zhengguo,Wu Tsunghsueh,Li Chunya
Icosahedral gold nanocrystals (AuNCs) were synthesized by using the ionic liquid (IL) 1-(10-bromodecyl)-3-methyl-imidazolium bromide as a morphology-controlling reagent. The novel IL 1,3-di-(3-mercaptopropyl)-imidazolium bromide was employed as a bifunctional monomer to integrate the AuNCs onto the surface of a glassy carbon electrode (GCE) modified with gold nanoparticles. After interaction with thioglycolic acid (TGA) and activation of the carboxy groups, the antibody against squamous cell carcinoma antigen was immobilized on the modified GCE. Residual active sites were blocked with bovine serum albumin. The new materials and the steps for immunosensor fabrication were fully characterized. The reduction in peak current (using hexacyanoferrate as an electrochemical probe) due to the recognition of SCCA is linearly related to the SCCA concentration in the 0.02 to 10 ng mL −1 concentration range. The detection limit is as low as 12.6 pg mL −1 (at an S/N ratio of 3). The assay was applied to the quantitation of SCCA in human serum samples. The accuracy was validated by comparison with an ELISA method. The two methods displayed excellent consistency.
Icosahedral gold nanocrystals were self-assembled onto a gold nanoparticle modified glassy carbon electrode surface by using 1,3-di-(3-mercaptopropyl)-imidazolium bromide ionic liquid as a linker. Antibody for squamous cell carcinoma antigen was immobilized onto the gold nanocrystal based interface to fabricate an immunosensor.
✓ 已验证
DOI
高影响因子
RESEARCH ON CHEMICAL INTERMEDIATES
·
2013
·Vol. 40
·期 4
·1575-1581
·
IF 0.88
Liu Feng,Wang Meiyan,Teng Xinhuan,Zhang Peizhi,Jiang Lin
A series of 2-(5-methyl-3-(4-chloro/trifluoromethylphenyl)isoxazol-4-yl)-5-arylamino-1,3,4-oxadiazoles were synthesized from 4-chloro/trifluoromethyl benzaldehyde, ethyl acetoacetate, hydroxylamine hydrochloride, hydrazine hydrate, and aryl isocyanate by multi-step reactions. The structures of the target compounds were elucidated by IR, 1 H NMR, MS, and elemental analysis. All these compounds were tested for in vitro antifungal activities against Botrytis cinerea and Rhizoctonia cerealis by the mycelium growth rate method, and the results indicated that some compounds displayed high antifungal activity against Botrytis cinerea.
✓ 已验证
DOI
高影响因子
Nano Research
·
2020
·Vol. 14
·期 5
·1471-1478
·
IF 8.183
Shao Weiwei,Li Xiaodong,Zu Xiaolong,Liang Liang,Pan Yang,Zhu Junfa,Wang Chengming,Sun Yongfu,Xie Yi
Photooxidation provides a promising strategy for removing the dominant indoor pollutant of HCHO, while the underlying photooxidation mechanism is still unclear, especially the exact role of H 2 O molecules. Herein, we utilize in-situ spectral techniques to unveil the H 2 O-mediated HCHO photooxidation mechanism. As an example, the synthetic defective Bi 2 WO 6 ultrathin sheets realize high-rate HCHO photooxidation with the assistance of H 2 O at room temperature. In-situ electron paramagnetic resonance spectroscopy demonstrates the existence of •OH radicals, possibly stemmed from H 2 O oxidation by the photoexcited holes. Synchrotron-radiation vacuum ultraviolet photoionization mass spectroscopy and H 2 18 O isotope-labeling experiment directly evidence the formed •OH radicals as the source of oxygen atoms, trigger HCHO photooxidation to produce CO 2 , while in-situ Fourier transform infrared spectroscopy discloses the HCOO* radical is the main photooxidation intermediate. Density-functional-theory calculations further reveal the •OH formation process is the rate-limiting step, strongly verifying the critical role of H 2 O in promoting HCHO photooxidation. This work first clearly uncovers the H 2 O-mediated HCHO photooxidation mechanism, holding promise for high-efficiency indoor HCHO removal at ambient conditions.
✓ 已验证
DOI
高影响因子
Chemistry Africa-A Journal of the Tunisian Chemical Society
·
2021
·Vol. 5
·期 1
·79-87
·
IF 0
Naz Farah,Ciprian Matteo,Luo Zhixiong,Yan Shilin,Iqbal Shahzad Zafar,Zhu Meifang,Chaemchuen Somboon,Verpoort Francis
The synthesis and use of MOF-derived Co/NCF (N-doped carbon framework) material as a heterogeneous catalyst for copolymers synthesis via ring-opening polymerization (ROP) are reported for the first time. The Co/NCF material is applied for the copolymerization of L -lactides (LA) and ε-caprolactone (ε-CL) as monomers via ROP in bulk without any solvent or co-catalyst. The as-prepared catalyst is characterized using XRD, TPD, XPS, SEM, and TEM analytical techniques. At the same time, 1 H and 13 C-NMR spectroscopy were used to analyze the microstructure of the copolymer confirming the random copolymer structure. The average r values calculated from the heterodiad analysis of the 1 H NMR, data were r LA = 0.96 and r CL = 0.93 and L value calculated from the triads analysis of 13 C NMR, data were L LA = 3.17 and L CL = 2.79, respectively. It has been observed that the melting temperature and glass transition temperature of the copolymer increases with higher LA content. The XRD and DSC analyses also confirmed that the as-synthesized copolymer possesses two phases corresponding to the polylactide and polycaprolactone, respectively. Additionally, the activity of Co/NCF is also compared with other Co-based heterogeneous catalysts to demonstrate its ability. Graphic Abstract
✓ 已验证
DOI
JOURNAL OF MATERIALS SCIENCE
·
2022
·Vol. 57
·期 9
·5596-5605
·
IF 4.682
Wang Meng,Chen Ming,Wang Qiuping,Yan Liqiang,Li Lin,Wang Xiuli,Wu Xiongzhi,Lei Chenghong
In this work, antimicrobial agent polylysine was deliberately used to functionalize carbon nanotubes and activated carbon to load antimicrobial enzyme lysozyme. Antimicrobial activity of the loaded lysozyme on polylysine-functionalized carbon materials was significantly enhanced, and the functionalizing agent exhibited its own apparent antimicrobial activity as well. Remarkably, antimicrobial ɛ-polylysine synergistically enhanced antimicrobial activity of loaded lysozyme on its functionalized carbon nanotubes to more than five times as high as the activity of free lysozyme in solution, in sharp contrast to that of loaded lysozyme on unfunctionalized carbon nanotubes or activated carbon, or functionalized activated carbon. The actual antimicrobial activity of loaded lysozyme on functionalized carbon nanotubes was applied with Bacillus subtilis , exhibiting much faster digesting lysis of the bacteria in comparison with free lysozyme. The results indicate that polylysine on carbon nanotubes played a dual role as the functionalizing and antimicrobial agent as expected. Synergistic and potent antimicrobial activities from combined action of antimicrobial enzyme and antimicrobial agent on carbon nanotubes provide a new antimicrobial protection for food and beverage industry and other biochemical processes.
✓ 已验证
DOI
高影响因子
Advanced Composites and Hybrid Materials
·
2021
·Vol. 4
·期 3
·552-561
·
IF 5.693
Yan Jia,Niu Yanfei,Wu Chunhua,Shi Zhengjun,Zhao Ping,Naik Nithesh,Mai Xianmin,Yuan Bingnan
As antimicrobial agents, essential oils (EOs) have been used by more and more companies as alternatives to traditional chemicals. In the study, seven EOs from Pinus massoniana , cinnamon , Star anise , Litsea cubeba , Cinnamomum camphora , Lemon eucalyptus , and Camphor from Guangxi were researched for their antifungal performances and chemical components. With the help of the diffusion in a disc way as well as the minimum inhibitory concentration (MIC) to three fungi, the antifungal impacts and the bamboo slices anti-mold tests of these EOs were studied. The compositions of these oils were identified. Litsea cubeba EO, Anise EO, and Cinnamon EO exhibited super antifungal activity against Trichoderma viride , Aspergillus niger , and Penicillium citrinum . Treated by Cinnamon EO, Anise EO, or Litsea cubeba EO, few molds were observed on the surface of bamboo chips, which showed that these EOs had a good antifungal effect on molds of bamboo. Graphical abstract Antifungal effect of seven essential oils on bamboo
✓ 已验证
DOI
高影响因子
Nano Research
·
2021
·Vol. 15
·期 1
·528-534
·
IF 8.897
Shen Chenqi,Wang Pengtang,Li Leigang,Huang Xiaoqing,Shao Qi
Syngas (CO + H 2 ) is the incredibly important feedstock for producing synthetic fuels and various value-added chemicals. CO 2 electrochemical reduction to syngas is an environmental-friendly and sustainable approach, but still challenging to produce tunable syngas with a wide ratio of CO/H 2 . Herein, by modulating the structure and phase, we have successfully obtained a series of copper-indium (Cu-In) catalysts, which are efficient for producing syngas with tunable CO/H 2 ratios. A series of CuIn bimetallic catalysts with different structures from hollow sphere to two-layer hollow sphere and different phases from CuO to Cu 2 O are developed. We find that the CO and H 2 are the only gaseous products, in which the CO/H 2 ratios can be readily tuned from 1.2 ± 0.1 to 9.0 ± 1.5 by simply controlling the thermal annealing temperature. It also exhibits high durability during a 10-h test. The unique performance is attributed to the modulated In enrichment on the Cu surfaces during the CO 2 reduction reaction, which causes the differences in binding energies for key reaction intermediates, thus resulting in the tunable composition of syngas. The present work emphasizes a simple yet efficient phase and structure modulating strategy for designing potential electrocatalysts for producing syngas with widely tunable CO/H 2 ratios.
✓ 已验证
DOI
高影响因子
JOURNAL OF NANOBIOTECHNOLOGY
·
2026
·
IF 15
Wang Lihang,Liu Botao,Lu Tingsheng,Luo Chunshan,Li Zhongzhe,Lin Yunfeng
Ankylosing spondylitis (AS) is a chronic systemic inflammatory disease affecting the spine, sacroiliac and peripheral joints, with TNF-α as a core pro-inflammatory cytokine. Macrophages, as major TNF-α producers, form a positive feedback loop that amplifies local inflammatory responses. The use of clinical TNF inhibitors such as infliximab is limited by their high cost and high recurrence rate. This study constructs a targeted nano-delivery system named RSV@tFNAs-TNFαapt, by conjugating TNF-α aptamer to tetrahedral DNA nanostructures and loading resveratrol, a natural polyphenol with potent anti-inflammatory, antioxidant and immunomodulatory activities. The nanosystem showed uniform morphology, good stability and high cell uptake efficiency. In vitro, it promotes M2 macrophage polarization, inhibits pro-inflammatory and tissue-destruction-related factors, and reduced ROS production in synovial fibroblasts. In an AS rat model, it improves motor function, relieves joint swelling, alleviates spinal inflammation and structural damage, and reduces the production of peripheral inflammatory factors. Histopathology results confirms less inflammatory cell infiltration and protected cartilage and bone structure. In summary, RSV@tFNAs-TNFαapt exerts significant targeted anti-inflammatory and joint-protective effects, providing a complementary therapeutic strategy for AS, especially for peripheral joint lesions. Graphical abstract
✓ 已验证
DOI
高影响因子
Science China-Materials
·
2025
·
IF 7.4
Cao Jueran,Huang Enlin,Zhong Ziting,Jiang Tingjie,Zhang Haoran,Li Wei,Zhang Xuejie,Hu Chaofan,Lei Bingfu
The integration of photochromism and photoluminescence in functional materials presents significant challenges, particularly in achieving broad-spectrum color modulation and rapid response. In this work, we have developed sodium-doped and sodium/boron co-doped CDs that exhibit dual-mode photochromic luminescent behavior through a novel radical-mediated mechanism. The Na-CDs demonstrated a 180 nm red-shift in emission, transitioning from 450 to 630 nm. The Na, B-CDs achieved blue-shifted, multicolor emission, progressing from orange to yellow and green under 30-s UV irradiation. Notably, the photochromic states spontaneously reverted to their initial configurations without external stimuli. These phenomena arise from photoinduced electron transfer between pristine CDs and light-generated anionic radicals. Leveraging these unique photochromic properties, we implemented reversible anti-counter-feiting systems and information encryption platforms. Furthermore, the photochromic CDs exhibit daylight-responsive UV detection capabilities and are functional in plant cell imaging, significantly expanding their potential applications in optoelectronic devices.
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）