JOURNAL OF MATERIALS ENGINEERING AND PERFORMANCE
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2026
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IF 2.6
Zhang Zilong,Liu Na,Chen Qianchi,Xiao Kaidan,Huang Lin,Lu Zhongchen
In this study, SiO 2 -coated flaky carbonyl iron powder (FCIP@SiO 2 ) composites with varying coating ratios were successfully fabricated using an acoustic resonance-assisted modification method. The effects of the SiO 2 coating on electromagnetic properties, microwave absorption performance, thermal stability, and corrosion resistance were systematically investigated. Electromagnetic characterization revealed that the SiO 2 coating effectively regulated the balance between conduction and polarization, optimized impedance matching, and suppressed excessive conductive losses, thereby improving microwave absorption. Notably, with a thickness of 4.0 mm, the FCIP@SiO 2 -5% sample achieved a remarkable minimum reflection loss of − 24.57 dB at 2.08 GHz (S-band), significantly outperforming the pristine FCIP. Regarding thermal stability, thermogravimetric analysis demonstrated that the dense SiO 2 shell significantly enhanced oxidation resistance. The onset oxidation temperature of the FCIP@SiO 2 -5% sample was delayed to 227.80 °C (an increase of ~ 83.5 °C compared to uncoated FCIP), and it exhibited the lowest total mass gain at 900 °C. Electrochemical tests indicated enhanced corrosion resistance, with the corrosion potential positively shifting from − 0.906 V to − 0.818 V. Graphical
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高影响因子
Nature Communications
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2026
·
IF 18.1
Chen Yongjin,Ren Hui,Xin Haoyue,Wu Xinzhou,Jiao Qingjie
Energetic materials are central to propulsion and detonation technologies, yet their performance is often limited by poor control over energy release across multiple length and time scales. Integrating highly reactive composites with molecular explosives while maintaining structural precision remains challenging. Here we show a three dimensional printing strategy that enables programmable energetic composites by combining highly reactive metastable composite systems with a crystalline high explosive through acoustic-assisted assembly. Uniform coating and intimate interfacial contact produce dense architectures with enhanced thermal reactivity, accelerated pressurisation and increased energy output under confined conditions. Printed filamentary and core–shell structures further enable multistage and geometry-dependent energy release, including sustained combustion, secondary pressurisation and intense fireball formation. Laser-driven and combustion experiments reveal that the energy release characteristics can be systematically tuned by composition and architecture. This work establishes a general route to structure–performance control in energetic materials and highlights additive manufacturing as a powerful platform for designing next-generation reactive and explosive systems.
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高影响因子
Scientific Reports
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2026
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IF 4.9
Wu Haotian,Liu Xianzheng,Jamadon Nashrah Hani,Li Feng,Tang Rongji,Zheng Liancheng
Amorphous carbon exhibits low initial coulombic efficiency due to its high specific surface area, abundant functional groups, and structural defects, limiting its application in sodium-ion batteries. The development of anode pre-sodiation reagents has diversified and achieved significant progress, yet research on the impact of reagent concentration on electrode electrochemical performance remains an unexplored area. This study systematically investigated the influence of pre-sodiation concentration on the electrochemical performance of porous carbon electrodes by subjecting them to chemical pre-sodiation treatment using sodium biphenyl solutions of varying concentrations. The results indicate that pre-sodiation treatment significantly enhances the electrode initial coulombic efficiency and cycling stability. When the pre-sodiation level is controlled to yield an initial coulombic efficiency below 100%, the electrode sodium storage capacity is promoted; however, when the initial coulombic efficiency exceeds 100%, the capacity is instead suppressed. In summary, rationally designing the concentration of sodium biphenyl solution to maximize the benefits of pre-sodiation is crucial for enhancing the electrochemical performance of sodium-ion batteries.
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PubMed
高影响因子
PLANT CELL REPORTS
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2026
·Vol. 45
·期 10
·321
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IF 5.3
Yan Xiao,Rao Mingxiang,Tao Yu,Ran Weixi,Wang Yuchun,Lv Wuyun,Ren Hengze,Chen Yanan,Lu Mengqian,Jing Tingting,Li Chunfang
Key message CsWRKY22 acts as a positive regulator of CsFLSd through binding to proCsFLSd, promoting quercetin accumulation in tea plants, which contributes to the astringent taste of tea. Flavonol derivatives, including quercetin, are nutritionally valuable dietary components with health benefits. In tea plants, their high accumulation not only contributes to the beverage’s nutritional quality but also influences its characteristic astringent taste. To gain a deeper insight into the mechanisms underlying flavonols biosynthesis in tea plants, this study first identified a candidate flavonol synthase-encoding gene, CsFLSd , via bioinformatic mining of the tea plant transcriptome. Functional validation showed that targeted manipulation of CsFLSd expression directly modulated quercetin levels: transient suppression of CsFLSd expression in tea plant leaves resulted in a significant reduction in quercetin content. Heterologous stable overexpression of CsFLSd in Arabidopsis thaliana further confirmed its role in promoting quercetin accumulation. To dissect the upstream regulation of CsFLSd , a Yeast One-Hybrid (Y1H) screen was performed using a tea plant cDNA library, leading to the identification of CsWRKY22 as a potential interacting partner of the CsFLSd promoter. Subsequent validation experiments revealed that CsWRKY22 could specifically bind to the CsFLSd promoter. Functional analyses demonstrated that transient overexpression of CsWRKY22 in tea plant leaves elevated the quercetin content, whereas transient suppression of its expression reduced quercetin accumulation, indicating that CsWRKY22 acts as a positive regulator of quercetin biosynthesis. Collectively, these findings characterize an important regulatory step in quercetin biosynthesis in tea plants, defined by the CsWRKY22 -proCsFLSd module that controls quercetin production. Additionally, this study provides valuable insights into flavonols biosynthesis in tea plants, advancing the understanding of flavonoid metabolic regulation in tea plants.
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高影响因子
JOM
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2026
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IF 2.3
Tian Zhiqiang,Wang Yu,Xu A-min,Chen Xinjie,Zhang Ting-An
This study systematically investigates the viscosity behavior of a potassium cryolite-based electrolyte (KF-AlF 3 ) over the temperature range of 450–800°C. Compared with previous measurements conducted at selected temperatures and cryolite ratios (CR), this work extends the viscosity characterization of potassium cryolite-based electrolytes across a wide temperature range covering both the practical electrolysis window and the solid–liquid coexistence region, while providing systematic insight into the effects of CR and Al 2 O 3 content. High-resolution viscosity–temperature data were obtained under controlled conditions with CR between 1.2 and 1.5 and Al 2 O 3 concentrations from 0 wt.% to 5 wt.%. The results indicate that viscosity is dominantly governed by the CR, while temperature and Al 2 O 3 content exert comparatively weaker effects. On average, viscosity increases by approximately 2.7% for every 0.1 wt.% increase in CR and by approximately 1.2% for each 1 wt.% increase in Al 2 O 3 content. Two distinct viscosity inflection points were observed in the 480–500°C interval. The primary inflection near 500°C corresponds to the onset of K 3 AlF 6 crystallization, whereas the secondary inflection around 480°C is tentatively attributed to enhanced interactions between Al 2 O 3 -derived solid particles during further cooling. A segmented Arrhenius-type model was established, providing a unified viscosity description across the investigated temperature and composition ranges with a mean relative deviation below 1.5%. The model parameters reveal a substantially higher activation energy in the low-temperature segment associated with solid–liquid coexistence, while the high-temperature regime exhibits mild viscosity variation characteristic of ionic-liquid-like behavior. This model is directly applicable to CFD-DEM coupled simulations and low-temperature aluminum electrolysis process optimization.
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高影响因子
ANALYTICAL SCIENCES
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2026
·
IF 2
Liang Jinhua,Ye Hongying,Yuan Zuhuan,Wu Zhaodi,Li Guizhen,Hao Ruizheng,Wu Xiaoqian,Cheng Shipei,Hu Yilin,Zhu Wenyuan
Hexavalent chromium (Cr(VI)), a highly toxic and carcinogenic environmental pollutant, poses severe threats to ecological balance and human health. Traditional colorimetric detection methods relying on peroxidase-like nanozymes often suffer from interference caused by reactive oxygen species (ROS) and coexisting redox-active substances, compromising their accuracy in complex water matrices. Herein, we report a novel H 2 O 2 -free colorimetric strategy for the ultrasensitive detection of Cr(VI) using atomically dispersed CuCo-NC catalysts. Unlike conventional mechanisms, the synergistic interplay between Cu and Co atoms modulates the electronic structure (d-band center), enabling Cr(VI) to act as a direct electron acceptor. This unique pathway facilitates the oxidation of TMB without generating ROS intermediates, thereby conferring exceptional resistance to common interferents such as Fe 2+ /Fe 3+ . The sensor exhibits a wide linear range (50–1000 nM) and an ultralow detection limit of 1.12 nM, surpassing many existing methods. Furthermore, the practical applicability of this probe is validated through the successful monitoring of Cr(VI) in real water samples (e.g., Guilin Lijiang River), demonstrating its robustness for on-site environmental surveillance. This work not only provides a reliable tool for early-warning monitoring of chromium pollution but also offers mechanistic insights into H 2 O 2 -free catalytic pathways. Graphical abstract Schematic illustration of the H 2 O 2 -free colorimetric sensing strategy using atomically dispersed CuCo-NC nanozymes. The synergistic Cu/Co dual sites enable Cr(VI) to act as a direct electron acceptor, bypassing the generation of reactive oxygen species (ROS) and thus eliminating interference from coexisting redox-active substances. This mechanism allows for the ultrasensitive and selective visual detection of Cr(VI) in real water environments
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高影响因子
BMC CANCER
·
2026
·Vol. 26
·期 1
·1086
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IF 4.1
Dou Bo,Wu Ruiqi,Ma Xiaolai,Hu Changhua,Duan Xiaoqun
Hyaluronidase (HAase) is an enzyme capable of degrading hyaluronic acid (HA). In anti-tumor therapy, HAase can enhance the efficacy of anti-cancer drugs by regulating the tumor microenvironment and overcoming drug delivery barriers, and it can also be used directly to inhibit tumor growth. In this study, we identified a previously uncharacterized HAase (Ph-HAase) from Pedobacter heparinus . After purification, the enzyme was obtained with a 43.08% recovery, a 47.5-fold purification, and a specific activity of 32.32 IU/mg. SDS-PAGE and LC-MS analyses revealed that the molecular weight of Ph-HAase was 79.6 kDa. Ph-HAase exhibited excellent stability at temperatures below 30 °C and within the pH range of 6.5 to 7.5. The enzyme activity was found to be relatively high at pH 6.5 and 45℃. Although HA served as the preferred substrate, Ph-HAase also exhibited degradative activity toward Chondroitin Sulfate (CS) and Dermatan Sulfate (DS). Notably, we found that Ph-HAase induced apoptosis in melanoma B16F10 cells via the mitochondrial pathway, characterized by loss of membrane potential and ROS accumulation, and affected the expression of apoptosis-related genes and proteins. In vivo studies further confirmed its anti-melanoma effect. This study is the first to report HAase derived from P. heparinus and to demonstrate its potential for melanoma treatment.
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高影响因子
MRS Communications
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2026
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IF 2.7
Li Mingze,Yuan Xin,Yang Qianpeng,Luo Qizhao,Wang Jing,Lan Weiyun,Lei Huan,Jiang Haifeng
Photothermal membrane distillation offers high desalination and strong environmental adaptability but suffers from pore-blocking salt crystallization that typically initiates at the pore edges. This work introduces a patterned membrane design that uses the Marangoni effect to restrict salt crystallization near the pore edges, sacrificing local flux to maintain overall vapor flux and ensure long-term operational stability. Under 1 kW/m 2 light and 0.6 mol/L NaCl, water production remains above 80% of the initial rate after 3 h, and the retention rate increases by 30%. The PTFE/PEGDA/graphene composite membrane effectively extends service life and boosts freshwater yield. Graphical abstract
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高影响因子
BIOTECHNOLOGY LETTERS
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2026
·Vol. 48
·期 5
·121
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IF 2.5
Chen Jiahui,Xu Han,Liu Tingting,Chen Ming,Yu Fang,Zhang Yue
Menaquinone-7 (MK-7), a highly preferred form of vitamin K2, has garnered extensive attention due to its long half-life in the human body and numerous nutritional and pharmacological benefits. To establish a cost-effective microbial platform for MK-7 production, we engineered the eukaryotic model organism Saccharomyces cerevisiae . The complete biosynthesis pathway was modularized into three parts: the endogenous mevalonate (MVA) pathway, the endogenous shikimate (SA) pathway, and a heterologous menaquinone (MK) module. Eleven key genes from the MK module were introduced into the yeast chassis using selection markers for His , Leu , and Met , creating the engineered strain YK-1. We then optimized the fermentation medium and conditions, and the MK-7 titer reached 0.413 mg/L. This represents a 31.1% increase over the non-optimized yield, demonstrating the successful de novo synthesis of MK-7 from simple carbon sources in a eukaryotic cell factory. This work not only expands the repertoire of chassis cells for MK-7 production but also provides a valuable framework for engineering biosynthesis pathways for other isoprenoids.
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高影响因子
MICROCHIMICA ACTA
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2026
·Vol. 193
·期 10
·697
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IF 5.4
Zhang Hui,Peng Weisen,Yu Manlin,Zou Can,Wen Kunhua,He Miao
The selective detection of different metal-ion pollutants is of great significance for assessing water quality and investigating pollution sources. To address this issue, a composite suspension of zeolitic imidazolate framework-8 and β-cyclodextrin (ZIF-8@β-CD) and functionalized a prism-based surface plasmon resonance (SPR) sensor with the suspension via drop casting has been prepared for the selective detection of Cu²⁺ in water. The interaction between ZIF-8 and Cu²⁺ is mainly related to ion exchange and coordination interaction, while the hydroxyl group on the surface of cavity-structured β-CD confers excellent selective binding ability with Cu²⁺. Based on these combined effects, the maximum resonance wavelength shift of the ZIF-8@β-CD-functionalized SPR sensor was 23.03 nm within a Cu²⁺ concentration range of 0–320 µM, while that was merely 5.12 nm for the sensor modified with ZIF-8 alone. Additionally, the introduction of β-CD produces a synergistic effect with ZIF-8, significantly enhancing the sensor’s selective capture capacity for Cu²⁺ relative to the tested interfering metal ions, including Cd²⁺, Zn²⁺, Cr³⁺, Fe³⁺, Co²⁺, Mn²⁺, Ca²⁺, and Mg²⁺. Consequently, the resonance wavelength shift showed a good linear relationship with Cu²⁺ concentration over the range 0–80 µM, yielding a sensitivity of 0.2 nm/µM and a LOD of 4.35 µM. This study presents a novel, straightforward strategy for functionalizing SPR sensor interfaces to enable high-performance, selective detection of Cu²⁺, with significant value for aquatic ecosystem monitoring and freshwater resource safety. Graphical
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高影响因子
JOURNAL OF NANOBIOTECHNOLOGY
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2026
·
IF 15
Li Shuyi,Li Yuguo,Wu Jiang,Gao Yue,Zeng Shiyi,Deng Hao,Hu Xin,Guo Quanyi,Xiao Jingang,Wei Jiawei
Dysregulation of chondrocyte metabolic networks and the physical barrier imposed by the extracellular matrix (ECM) represent primary bottlenecks in precision intervention for osteoarthritis (OA). We engineered an environment-responsive, charge-adaptive biomimetic nanoplatform, IM@PP-R, in which the metabolic modulator RCGD423 was encapsulated within a polycaprolactone (PCL) core via flash nanoprecipitation (FNP), then cloaked with a hybrid shell of neutrophil membranes and ionizable lipids. In the mildly acidic OA microenvironment (pH 6.4–6.8), IM@PP-R undergoes surface charge inversion from negative to positive, converting electrostatic ECM repulsion into attraction to facilitate deep cartilage penetration. Both in vitro and in vivo, IM@PP-R treatment was associated with improved mitochondrial status and attenuated oxidative stress. This process was closely linked to a redirection of the arachidonic acid (ARA) metabolic profile: integrated transcriptomic and metabolomic analyses revealed the downregulation of pro-inflammatory enzymes (ALOX5, mPGES-1) alongside a partial recovery of the IL-1β-suppressed pro-resolving enzyme CYP2J4. These enzymatic shifts corresponded with a transition from PGE2 toward PGA2/PGJ2 accumulation, suggestive of a reprogrammed lipid mediator profile. In a rat ACLT model, IM@PP-R significantly prolonged joint residence time and attenuated osteochondral degeneration. This study presents a translatable strategy for overcoming dense tissue barriers to achieve intracellular metabolic reprogramming in OA. Graphical
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高影响因子
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
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2026
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IF 4.1
Guan Xinhui,Zhang Yuying,Ma Xiaoqiao,Wang Haiyan,Qiao Xiaoqiang,Gu Xiaofei
Comprehensive characterization of exosomal phospholipids is essential for understanding cancer-associated metabolic alterations and discovering potential biomarkers, but remains challenging due to their extensive structural diversity and the limited selectivity and coverage of conventional liquid chromatography-tandem mass spectrometry (LC-MS/MS) approaches. In this study, an ionic liquid-functionalized styrene-maleic anhydride copolymer brush stationary phase (Sil-BHHICl) was developed and integrated into an offline two-dimensional (2D) LC-MS/MS platform for comprehensive exosomal phospholipid profiling. The Sil-BHHICl stationary phase exhibited a hydrophilic interaction/reversed-phase mixed-mode retention mechanism and provided enhanced selectivity toward phospholipids, enabling efficient separation at both the phospholipid-class and molecular-species levels. The developed analytical platform enabled comprehensive profiling of plasma-derived exosomal phospholipids, resulting in the identification of 274 molecular species belonging to 10 phospholipid classes. Lipidomic analysis of plasma exosomes from breast cancer patients and healthy controls revealed distinct phospholipid alterations associated with breast cancer and identified five candidate biomarkers, among which LysoPC-O (16:0) exhibited the strongest discriminatory ability. Pathway enrichment analysis further indicated that the altered phospholipids were predominantly associated with glycerophospholipid metabolism, suggesting extensive lipid metabolic remodeling in breast cancer. Overall, this study establishes a mixed-mode chromatographic platform for high-coverage exosomal phospholipid profiling and demonstrates its potential for lipidomics-based biomarker discovery and investigation of disease-associated metabolic alterations. Graphical abstract
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高影响因子
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