NEW JOURNAL OF CHEMISTRY
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2017
·Vol. 41
·期 21
·13043-13050
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IF 3.269
Huiqi Wang,Zheng Li,Wei Feng,Qiong Jia
A covalent organic framework (COF) is an intriguing porous material with unique properties and can be promisingly used as a functional material for microextraction. In the current study, a COF was introduced into a poly(glycidyl methacrylate–ethylene dimethacrylate) monolith inside a capillary via photo-induced thiol-epoxy click polymerization to prepare a novel polymer monolith microextraction material. The COF functionalized monolith was characterized using scanning electron microscopy, Fourier-transformed infrared spectroscopy, X-ray photoelectron spectroscopy, and thermal gravimetric analysis. Under optimized conditions, acceptable linearities, low limits of detection, and good intra-day/inter-day relative standard deviations were obtained for benzophenones by coupling with an HPLC instrument. The developed method was employed for the preconcentration and determination of benzophenones in human urine and serum samples and was assessed through recovery studies.
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Nanoscale
·
2017
·Vol. 10
·期 3
·1111-1118
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IF 7.367
Xu Chen,Xueke Sun,Wen Xu,Gencai Pan,Donglei Zhou,Jinyang Zhu,He Wang,Xue Bai,Biao Dong,Hongwei Song
Intracellular pH sensing is of importance and can be used as an indicator for monitoring the evolution of various diseases and the health of cells. Here, we developed a new class of surface-functionalized MXene quantum dots (QDs), Ti3C2, by the sonication cutting and hydrothermal approach and further explored their intracellular pH sensing. The functionalized Ti3C2 QDs exhibit bright excitation-dependent blue photoluminescence (PL) originating from the size effect and surface defects. Meanwhile, Ti3C2 QDs demonstrate a high PL response induced by the deprotonation of the surface defects. Furthermore, combining the highly pH sensitive Ti3C2 QDs with the pH insensitive [Ru(dpp)3]Cl2, we developed a ratiometric pH sensor to quantitatively monitor the intracellular pH values. These novel MXene quantum dots can serve as a promising platform for developing practical fluorescent nanosensors.
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FOOD AND AGRICULTURAL IMMUNOLOGY
·
2017
·
IF 1.392
Liqiang Liu,Liguang Xu,Steven Suryoprabowo,Shanshan Song,Hua Kuang
In this paper, we describe the development of a rapid, simple, specific, and sensitive immunochromatographic strip test based on an antibody–antigen reaction for detection of tulathromycin (TULA) in samples of 0.01 M PBS pH 7.4, pure milk and honey. The monoclonal antibodies specifically recognized the corresponding antigens produced in our laboratory. Under optimized conditions, the cut-off limits of the test strips for TULA in 0.01 M PBS pH 7.4 was found to be 2.5 ng/mL. Meanwhile, with simple preparation for detection in pure milk and honey samples, the cut-off limits for TULA were found to be 5 and 10 ng/mL, respectively. Each test can be evaluated in 5 min. In summary, this lateral-flow device provides a sensitive, effective, specific, and rapid method for detection of TULA residues in food matrix.
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POLYMER ENGINEERING AND SCIENCE
·
2017
·Vol. 58
·期 9
·1548-1554
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IF 1.449
Yinghong Xiao,Xue Chen,Tongxin Wang,Xiaodi Yang,James Mitchell
Nanoscale components at neural interface are crucial factors for neural devices due to the complex nanoscale structure of neural tissue. Nitrogen-doped graphene (g-C 3 N 4 ) was prepared and applied as a candidate material for the surface modification of neural electrodes. To better explore the practical applications of g-C 3 N 4 , a conducting polymer of poly(3,4-ethylenedioxythiophene) (PEDOT) was employed and a nanoporous composite of g-C 3 N 4 /PEDOT was achieved with excellent electrochemical performance including low interfacial impedance, high electric capacity, and long-term stability. Investigation revealed that the enhanced performance of the composite was attributed to its unique nanostructure, which was confirmed by field emission scanning electron microscopy, as well as the synergistic effect of the two components. Moreover, in vitro experiments demonstrated that g-C 3 N 4 /PEDOT promoted robust cell growth, possessing excellent biocompatibility. Our study validates that the g-C 3 N 4 /PEDOT nanocomposite is a promising candidate material to construct the interface between neural tissue and neural electrodes. POLYM. ENG. SCI., 58:1548–1554, 2018. © 2017 Society of Plastics Engineers
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Journal of Materials Chemistry B
·
2017
·Vol. 6
·期 1
·68-74
·
IF 4.543
Jingcai He,Junjian Chen,Guansong Hu,Lin Wang,Jian Zheng,Jiezhao Zhan,Yuchen Zhu,Chunting Zhong,Xuetao Shi,Sa Liu,Yingjun Wang,Li Ren
Infections associated with biomedical implants and devices pose a serious clinical challenge in hospitals worldwide. Antimicrobial peptides (AMPs) have become a great prospect to inhibit this type of infection due to their broad-spectrum antimicrobial activity and low cytotoxicity. However, it is still a challenge to apply AMPs on the biomaterial surface as the activity of AMPs is sensitive to salt or enzyme. In the present study, we prepared a spacer molecule, poly[2-(methacryloyloxy)ethyl]dimethyl-(3-sulfopropyl)ammonium hydroxide (polySBMA), on a model silicon surface via surface-initiated atom transfer radical polymerization (SI-ATRP). We then modified the antimicrobial peptide HHC36 (KRWWKWWRR) with L-propargylglycine (PraAMP) to improve its salt-tolerant activity and integrated PraAMP onto the spacer molecule using click chemistry. We employed X-ray photoelectron spectroscopy (XPS), contact angle goniometry, and atomic force microscopy (AFM) to confirm the success of the immobilization process. We also characterized the antimicrobial activity and stability of the surface with an antimicrobial assay. The results reveal that the modified surface exhibits good antimicrobial activity to inhibit 98.26% of E. coli, 83.72% of S. aureus, and 81.59% of P. aeruginosa. Furthermore, as compared to the control group without the polySBMA spacer, the modified surface improved its resistance to enzymolysis. An in vitro CCK-8 assay also illustrated that this surface showed negligible cytotoxicity to mouse bone mesenchymal stem cells.
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APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY
·
2017
·Vol. 185
·期 2
·385-395
·
IF 1.751
Cao Hao,Li Chengcheng,Zhao Jing,Wang Fang,Tan Tianwei,Liu Luo
Glutathione (GSH) is an important reducing agent in the living cells. It is synthesized by a two-step reaction and requires two molecules of adenosine triphosphate (ATP) for one molecule GSH. The enzymatic cascade reaction in vitro is a promising approach to achieve a high titer and limit side reactions; although, a cost-effective phosphate donor for ATP regeneration is required. Triphosphate (PolyP (3) ), tetraphosphate (PolyP (4) ), and hexametaphosphate (PolyP (6) ) were investigated in this study. Triphosphate inhibited the bifunctional GSH synthetase (GshF) from Streptococcus agalactiae , while no significant inhibition was observed by adding hexametaphosphate. The polyphosphate kinase from Corynebacterium glutamicum was hence investigated to use hexametaphosphate for regeneration of ATP. Further, the orthogonal experiment, which includes seven factors (buffer concentration, pH value, ADP concentration, GshF dosage, polyphosphate kinase (PPK) dosage, reaction temperature, substrate ratio of amino acid, and reaction times), indicated that the capacity of buffer is the most significant factor of the reaction conditions for enzymatic production of glutathione coupling with a PPK-based ATP regeneration system. After optimizing the Mg 2+ concentration, the reaction was scaled up to 250 mL in a stirred reactor with pH feedback control to stabilize the pH value of reaction system and nitrogen protection to avoid the oxidation of product. A yield of 12.32 g/L was achieved. This work provided a potential GshF-based enzymatic way coupling the PPK-based ATP regeneration to product GSH in the optimal conditions towards cost-effectiveness at the industrial scale.
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Journal of Energy Storage
·
2024
·
IF 8.9
Wenshuang Tian,Xiong Zheng,Yang Xiao,Guangzhao Qin
Photovoltaic (PV) power generation technology is currently one of the most effective ways in solar energy utilization, while current PV panels are facing a serious issue of electrical efficiency reduction and potential structural damage caused by the accumulated heat during operation. To solve this issue, we proposed a novel hybrid system containing PV cell, thermoelectric generation (TEG) module, and phase change composite (PCC), which can achieve a power enhancement of 29.8 % compared with individual PV cell. The fabricated chitosan-based PCC has a high anisotropy degree of 4.10 and melting enthalpy of 133.2 kJ·kg −1 , which promote the effective heat transport and storage between PV cell and TEG module, and the excellent mechanical strength and thermal stability ensures its long-term endurance. Owing to excellent thermal properties of the PCC, not only the power of PV cell is increased by 55.9 mW, but the TEG module also continuously outputs 4.1 mW of power. Besides, the hybrid system can produce 5.185 kW·h·m −2 electricity per day in the actual environment. Looking ahead, the integration of advanced materials and hybrid systems like the PV + PCC + TEG approach holds great promise for further enhancing solar energy efficiency and sustainability in real-world applications.
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Scientific Reports
·
2025
·Vol. 15
·期 1
·1-6
·
IF 3.9
Li Wenfang,Lu Yuze,Wang Jiajun,Li Chuanbi
In this study, a novel artificial enzyme Zn(II)-SMM with simple organic structure for PNPA-directed hydrolysis is proposed. The introduction of hydrophobic quinoline and dipyridinium in Zn(II)-SMM system demonstrates high activity for the complexation of Zn 2+ and hydrolysis of PNPA, and the catalytic rate (k cat /k uncat ) exceeds 5239 times that of non-catalytic systems. The newly designed small molecule organic complex effectively binds to and catalyzes the hydrolysis of substrate PNPA in accordance with Michaelis-Menten kinetics. The mechanism with activation by single Lewis acid provides fundamental insights for the development of small molecule hydrolases.
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CHEMICAL ENGINEERING JOURNAL
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2024
·
IF 13.3
Chang Li,Qingrui Dai,Jiaxin Jiang,Weidong Wu,Dong Yu Zhu,Xueqing Qiu
Ongoing innovation in bio-based plastics aims to meet more economical and diverse societal needs. However, the dependence on a single biomass source and the generally inadequate wet stability and moisture mechanical properties of traditional bio-based plastics severely limit their competitiveness. We have developed a high mechanical performance, fully bio-based, thermoset in-suit plastic from an almost worthless agricultural and forestry waste (eucalyptus) through a simple and environmentally friendly deconstruction-reconstruction strategy. In this process, the hydrogen and covalent bonds in the lignin and cellulose of eucalyptus are broken and then reorganised through dynamic covalent bonds. The resulting eucalyptus-based plastic exhibits high mechanical strength, excellent water resistance, UV ageing resistance, photothermal performance and light/heat controllable shape memory properties. By preserving the original structure of the lignin and cellulose, its natural degradability is ensured. This strategy for developing full-component plastics from solid agricultural and forestry waste offers a new approach to producing more competitive fully bio-based plastics.
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COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
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2025
·
IF 5.4
Lechen Yang,Yong Li,Dajun Huan,Chunling Zhu
To address the hazards posed by icing environments on flight safety, a series of anti-icing measures for aircraft have gradually developed. However, with the continuous enhancement of aircraft aerodynamic performance, especially the desire for engines and propellers to achieve higher fuel efficiency, optimization of modern aircraft anti-icing protection systems is required. Here, a method was proposed for creating a robust superhydrophobic photothermal coating with a micro-nano hierarchical structure by spraying on ice-prone areas of the aircraft, aimed at reducing the high energy consumption and cost of anti-icing systems. The superhydrophobic structure on the coating surface exhibited a static water contact angle of 159.5° and extremely low liquid adhesion, demonstrating excellent stability after mechanical wear, chemical corrosion, and ultraviolet irradiation tests. This structure allowed droplets to rebound quickly upon impact with the coating and completely detach within 11 ms, and could significantly delay the icing time of droplets on the coating surface in low-temperature environments, showing good anti-icing performance. The photothermal conversion performance of the coating ensured effective self-deicing under sunny conditions. Furthermore, icing wind tunnel tests validated the coating's anti-icing performance and photothermal effects, revealing that this coating could significantly reduce ice accumulation thickness. The results of this study provide options for achieving a low-energy, low-cost, and sustainable aircraft anti-icing protection system, conducive to the development of new anti-icing technologies.
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Analytical Methods
·
2024
·
IF 2.7
Yang Zhen,Jingyuan Chen,mengyu Liu,Jiabao Huang,Jieping Liang,Mengjiao Zhu,Yuanwei Shen,Danqing Li,Chong Lei,Xuecheng Sun
An integrated magnetoimpedance (MI) biosensor microfluidic magnetic platform was proposed for the evaluation of of cardiac markers cardiac troponin-I (cTnI). The bioanalytes evaluation platform mainly contained external permanent magnets (PMs), MI elements, peelable SiO2film units and microfluidic chip (MFC). The MI elements were made of micro-electro-mechanical system (MEMS)-based multilayered [Ti(6 nm)/FeNi(100 nm)]5/Cu(400 nm)/[Ti(6 nm)/FeNi(100 nm)]5 thin films and designed as meander structures with closed magnetic flux. The MFC was fabricated by using 3D printing and inverted molding techniques, and designed with a solution mixing reaction region, a magnetic separation region and detection regions. Peelable SiO2 film units with the same size as the MI sensing element are used for bioanalytes immunoreactivity interface. Two large PMs were placed directly below the MI sensing unit to provide a bias magnetic field, and the smaller PM was embedded in MCF for magnetic separation function. The different concentration biological target (cTnI antigen), PBS buffer and Dynabeads labeled polyclonal cTnI antibody solution are injected sequentially into the MCF. After immunoreactivity and magnetic separation, a classical sandwich immunoreaction process occured on the surface of the monoclonal antibody-modified SiO2 film via self-assembling technology in the reaction region of MFC. The fundamental principle for evaluation of cTnI was based on variation of the MI signal under different concentration biological target coupled with different number of Dynabeads. It was demonstrated that the mentioned MI-based magnetic platform can perform detection analyses over a range of cTnI concentrations (lowest concentration 0.1 ng/ml and highest concentration 100 ng/ml). The proposed MI-based magnetic platform provides a sensitive, reliable, stable and reusable bioanalytical platform and has potential for future biomedical applications.
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ADVANCED MATERIALS
·
2024
·Vol. 36
·期 31
·2403411
·
IF 27.4
Xiaojia Du,Hai Wang,Yunfei Wang,Zhiqiang Cao,Leyi Yang,Xiaohu Shi,Xiaoxu Zhang,Chengzhi He,Xiaodan Gu,Nan Liu
Understanding psychology is an important task in modern society which helps predict human behavior and provide feedback accordingly. Monitoring of weak psychological and emotional changes requires bioelectronic devices to be stretchable and compliant for unobtrusive and high-fidelity signal acquisition. Thin conductive polymer film is regarded as an ideal interface; however, it is very challenging to simultaneously balance mechanical robustness and opto-electrical property. Here, a 40 nm-thick film based on photolithographic double-network conductive polymer mediated by graphene layer is reported, which concurrently enables stretchability, conductivity, and conformability. Photolithographic polymer and graphene endow the film photopatternability, enhance stress dissipation capability, as well as improve opto-electrical conductivity (4458 S cm −1 @>90% transparency) through molecular rearrangement by π–π interaction, electrostatic interaction, and hydrogen bonding. The film is further applied onto corrugated facial skin, the subtle electromyogram is monitored, and machine learning algorithm is performed to understand complex emotions, indicating the outstanding ability for stretchable and compliant bioelectronics.
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