MOLECULES
·
2017
·Vol. 22
·期 6
·970
·
IF 2.861
Ming-Xia Song,Song-Hui Li,Jiao-Yang Peng,Ting-Ting Guo,Wen-Hui Xu,Shao-Feng Xiong,Xian-Qing Deng
Due to the rapidly growing bacterial resistance to antibiotics and the scarcity of novel agents under development, bacterial infections are still a pressing global problem, making new types of antibacterial agents, which are effective both alone and in combination with traditional antibiotics, urgently needed. In this paper, seven series ofN-arylsulfonylindole analogs5–11bearing rhodanine moieties were synthesized, characterized, and evaluated for antibacterial activity. According to the in vitro antimicrobial results, half of the synthesized compounds showed potent inhibition against four Gram-positive bacteria, with MIC values in the range of 0.5–8 µg/mL. For multidrug-resistant strains, compounds6aand6cwere the most potent, with MIC values of 0.5 µg/mL, having comparable activity to gatifloxacin, moxiflocaxin and norfloxacin and being 128-fold more potent than oxacillin (MIC = 64 µg/mL) and 64-fold more active than penicillin (MIC = 32 µg/mL) againstStaphylococcus aureusATCC 43300.
✓ 已验证
DOI
高影响因子
Nanoscale
·
2013
·Vol. 5
·期 20
·9764-9772
·
IF 6.233
Dongfang Hou,Xianluo Hu,Pei Hu,Wei Zhang,Mingfei Zhang,Yunhui Huang
A novel p–n junction photocatalyst of Bi4Ti3O12 nanofibers–BiOI nanosheets has been fabricated through a simple and economical technique of electrospinning combined with a successive ionic layer adsorption and reaction (SILAR) process. The products are characterized by X-ray diffraction (XRD), scanning electron microscopy (SEM), energy-dispersive X-ray spectroscopy (EDX), high-resolution transmission electron microscopy (HRTEM), X-ray photoelectron spectroscopy (XPS), UV-visible diffuse reflectance spectra (DRS), and photoluminescence (PL) spectroscopy. The as-formed Bi4Ti3O12 nanofibers are composed of inter-linked nanoparticles of 50–80 nm in size. The thickness of the as-grown BiOI nanosheets is about 10 nm and the size of the BiOI nanosheets increases with the SILAR cycles. In particular, many {001} facets of BiOI nanosheets are exposed, which is favorable to enhance the visible-light photocatalytic activity. The p–n junction photocatalyst exhibits enhanced visible-light-driven photocatalytic activity for decomposition of rhodamine B (RhB) and phenol. The enhanced photocatalytic activity can be attributed to the extended absorption in the visible light region resulting from the BiOI nanosheets and the effective separation of photogenerated carriers driven by the photo-induced potential difference generated at the Bi4Ti3O12–BiOI p–n junction interface.
✓ 已验证
DOI
高影响因子
Energy Technology
·
2019
·Vol. 7
·期 4
·1800963
·
IF 3.163
Maiyong Zhu,Qi Chen,Jiarui Kan,Jingjing Tang,Wenjing Wei,Jinkun Lin,Songjun Li
Herein, a sequential pyrolysis and oxidation strategy is developed to prepare Co 3 O 4 nanoparticles embedded in N-doped porous carbon (Co 3 O 4 @N-pC) using a bimetal zeolitic imidazolate framework (ZIF-67@ZIF-8) as precursors, which is first obtained via a simple wet-chemical process. The electrochemical performances of Co 3 O 4 @N-pC, ZIF-67@ZIF-8 precursors, and Co@N-Pc intermediates (the direct pyrolysis products from ZIF-67@ZIF-8) are studied as supercapacitor electrodes in comparison. The results reveal that the specific capacitance of the optimized Co 3 O 4 @N-pC electrode can reach up to 422.8 F g −1 at 1 A g −1 with a good rate capability (256 F g −1 at 5 A g −1 ) and excellent long-term cycling stability (87.9% retention after 5000 cycles). Such performance is superior over ZIF-67@ZIF-8 precursors (232 F g −1 at 1 A g −1 , 168.9 F g −1 at 5 A g −1 , and 82.7% retained after 5000 cycles) and Co@N-pC intermediates (218.4 F g −1 at 1 A g −1 , 171 F g −1 at 5 A g −1 , and 76.3% retained after 5000 cycles). The findings in this work are expected to provide a new avenue to explore other metal oxide/carbon materials for various applications.
✓ 已验证
DOI
高影响因子
JOURNAL OF COLLOID AND INTERFACE SCIENCE
·
2020
·
IF 7.489
Xiaoqing Huang,Wenbiao Zhang,Chaojin Zhou,Lichun Yang,Hui Wang,Qingsheng Gao,Min Zhu
Volume expansion and poor conductivity result in poor cyclability and low rate capability, which are the major challenges of transition-metal oxide as anode materials for sodium-ion batteries (SIBs). Herein, N -doped carbon encapsulated CoMoO 4 (CoMoO 4 @NC) nanorods are developed as excellent anode materials for SIBs with long-cycle life. The N -doped carbon shells serve as buffer to accommodate severe volume changes during sodiation/desodiation, and at the same time improve electronic conductivity and activate surface sites of CoMoO 4 . The optimized composite presents rapid reaction kinetics and excellent cycle stability. Even at a high current density of 1 A g −1 , it still shows long-cycle life and maintains specific capacity of 190 mAh g −1 after 3200 cycles. Furthermore, CoMoO 4 @NC anode is applied to match with Na 3 V 2 (PO 4 ) 3 cathode to assemble full-cells, in which it accomplishes reversible capacity of 152 mAh g −1 after 100 cycles, with capacity retention of 75% at a current density of 1 A g −1 , highlighting the practical application for SIBs.
✓ 已验证
DOI
高影响因子
Journal of Energy Storage
·
2024
·
IF 8.9
Qing Xu,Pengcheng Cai,Xuanyuan Ni,Yunxing Zhao,Denian Li,Yong Chen,Haoran Yuan
Electronic-double-layer supercapacitors (EDLC) usually use activated carbon with large specific surface area and abundant pore structure as the electrode active material for adsorption/desorption of electrolyte ions. Featuring huge yield, low price, multi-level structure, and inherent heteroatoms/functional groups, biomass-derived activated carbon has been demonstrating excellent specific capacitance, low electrochemical impedance, and long-term durability in supercapacitor applications. Loofah sponge is an ideal precursor for activated carbon because of its unique cross-linked parallel channel structure that facilitates ion transfer and storage in supercapacitor. Upon pre‑carbonization combined with KHCO 3 -incorporated activation pyrolysis in this study, the loofah sponge is transformed into a three-dimensional hierarchical porous structured carbon (LC-K1–800), while retaining the primary skeleton and heteroatoms (oxygen and nitrogen) of the biomass. The specific capacitance of LC-K1–800 at a current density of 0.2 A g −1 is measured to be 344 F g −1 , and that at a current density of 1 A g −1 is 296 F g −1 . Moreover, the symmetric two-electrode device assembled by the LC-K1–800 has a specific capacitance of 216 F g −1 at the current density of 0.2 A g −1 and a capacitance retention rate of 103.4 % after 10,000 charge/discharge cycles at the current density of 10 A g −1 , showcasing exceptional cycling stability. Additionally, the symmetric supercapacitor assembled with 1 M Na 2 SO 4 electrolyte has achieved an energy density of 18 Wh kg −1 in a 1.6 V voltage window. The impressive performance of the LC-K1–800 assembled EDLC is derived from the well-developed hierarchical porous structure, robust carbon skeleton, high specific surface area, as well as the superior hydrophilicity of loofah sponge-derived activated carbon. This work provides an outstanding option for high-performance and cost-effective carbon-based EDLC.
✓ 已验证
产品关联
DOI
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2024
·
IF 13.3
Yanhua Liu,Geoffrey I.N. Waterhouse,Xiaohui Jiang,Zhiming Zhang,Liangmin Yu
Marine biofouling profoundly affects the economic viability of the marine sector. With a view towards addressing this issue, this work reported the successful development of smart photo-responsive and thermo-responsive antibiofouling coatings by combining photothermally-active polyaniline (PANI) with temperature-sensitive poly(N-isopropylacrylamide) (PNIPAM). Under light irradiation, the PNIPAM/PANI coating could be photothermally heated to temperatures as high as 89.3 ± 1.6 °C, delivering a maximum antibacterial rate of 99.99 %. Impressively, light-induced temperature changes in the PNIPAM/PANI coating caused dynamic changes in film morphology and wettability. Upon lowering the temperature to below the lower critical solution temperature (LCST) of PNIPAM, the water contact angle of the PNIPAM/PANI coating decreased from 81° to 35° and the coating surface roughened appreciably, resulting in a 99.99 % release rate for both E.coli and S. aureus , thus achieving a dynamic self-cleaning effect. Furthermore, the developed PNIPAM/PANI coating demonstrated excellent resistance against protein and algae adhesion. These findings showcase the broad application potential of PNIPAM/PANI antifouling coatings in the marine sector.
✓ 已验证
产品关联
DOI
高影响因子
CARBON
·
2025
·
IF 11.6
Hengyu Hao,Jiajiang Zhou,Li Tong,Richard Lee Smith,Feng Shen,Haixin Guo
Selective and efficient oxidation of glucose to sugar acids is a challenge for sustainable chemistry. This study develops catalytic nitrogen-doped biocarbon materials having PtZn bimetallic alloy active sites that promote selective and efficient oxidation of glucose at room temperature without the use of any type of additives. Spectral analyses were used to verify that nitrogen was incorporated into the lattice of the PtZn 1.7 alloy through Zn-N bond coordination. Urea was used as the nitrogen source for preparing PtZn@C-U catalyst that achieved sugar acid yields as high as 95.5% (84.7% gluconic acid, 10.8 % glucaric acid) under atmospheric conditions and ambient temperature (23 °C) in neutral water without alkali. The presence of urea in the synthesis procedure not only promoted biocarbon growth but also generated unsaturated carbon bonds, enhancing the hydrophobicity of the PtZn@C-U. This increase in hydrophobicity led to the exposure of active oxygen sites on the catalyst surface, which functioned as alloy active sites, contributing to the high catalytic performance in aqueous media. The catalyst offers cyclability and stability via N-doping and represents an advance in catalyst design for production of organic acids at ambient conditions.
✓ 已验证
产品关联
DOI
高影响因子
ELECTROCHIMICA ACTA
·
2024
·
IF 5.5
Lei Zhang,Bing Sun,Qinghua Liu,Lin Song,Teibang Zhang,Xiaobo Duan
Extensive research has focused on the lithium (Li) metal anode, but progress in developing this technology has been hindered by the formation of lithium dendrites and their irreversible effects. In this study, an inorganic LiF-Li 3 N-rich solid electrolyte interface (SEI) is established in ether electrolyte through the direct use of 2,3-difluoro-5-(trifluoromethyl)pyridine (DP) to enable uniform Li deposition and enhance interfacial properties for a stable Li metal anode. Theoretical calculations show that DP has a higher tendency to decompose on lithium metal. An alternative approach involving the inclusion of additional anions into the solvation sheath of Li + ions using weakly solvating solvents is proposed. During Li plating, DP is reduced to form a LiF and Li 3 N-rich SEI, resulting in a heterogeneous SEI layer on the Li metal anode surface. This approach allows stable cycling of Li|Li cells for over 1800 h at current densities of 5 mA cm −2 and 15 mAh cm −2 . The method presented here has potential significance in the identification of suitable electrolytes for future research on lithium metal anodes.
✓ 已验证
产品关联
DOI
高影响因子
Nature Communications
·
2024
·Vol. 15
·期 1
·1-10
·
IF 14.7
Gong Cheng,Li Haiyun,Wang Huaxin,Zhang Cong,Zhuang Qixin,Wang Awen,Xu Zhiyuan,Cai Wensi,Li Ru,Li Xiong,Zang Zhigang
The bidirectional migration of halides and silver causes irreversible chemical corrosion to the electrodes and perovskite layer, affecting long-term operation stability of perovskite solar cells. Here we propose a silver coordination-induced n-doping of [6,6]-phenyl-C 61 -butyric acid methyl ester strategy to safeguard Ag electrode against corrosion and impede the migration of iodine within the PSCs. Meanwhile, the coordination between DCBP and silver induces n-doping in the PCBM layer, accelerating electron extraction from the perovskite layer. The resultant PSCs demonstrate an efficiency of 26.03% (certified 25.51%) with a minimal non-radiative voltage loss of 126 mV. The PCE of resulting devices retain 95% of their initial value after 2500 h of continuous maximum power point tracking under one-sun irradiation, and > 90% of their initial value even after 1500 h of accelerated aging at 85 °C and 85% relative humidity.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF MEDICINAL CHEMISTRY
·
2024
·
IF 6.8
Yi Huang,Fengling Liu,Shuhua Ren,Yuanqing Ding,Man Chi,Weiwei Huang,Wenjing Gu,Hewen Qian,Yaxia Yuan,Shurong Hou,Xiabin Chen,Lei Ma
Idiopathic pulmonary fibrosis (IPF) is a progressive and lethal lung disease with an elusive etiology. Aberrant activation of c-Jun N-terminal kinase 1 (JNK1) has been implicated in its pathogenesis. Through a combination of structure-based drug design and structure–activity relationship (SAR) optimization, a series of pyrimidine-2,4-diamine scaffold derivatives have been developed as potent JNK1 inhibitors. Compound E1 was identified with low nanomolar JNK1 inhibitory potency (IC50 = 2.7 nM). The introduction of a dimethylamine side chain has significantly enhanced the ability of E1 to inhibit c-Jun phosphorylation, surpassing the clinical candidate CC-90001. Molecular dynamics simulations revealed a binding free energy of −50.46 kcal/mol for E1. Moreover, E1 displayed satisfactory pharmacokinetic properties, with a bioavailability of 69% in rats. Furthermore, compound E1 exerted significant antifibrotic effects in a bleomycin-induced IPF mouse model and prevented a TGF-β-induced epithelial-to-mesenchymal transition in vitro. These findings position E1 as a promising lead for further drug development targeting IPF.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF COLLOID AND INTERFACE SCIENCE
·
2024
·
IF 9.4
Yongjie Jiang,Anqi Li,Qichang Pan,Shunchao Wang,Man Zhang,Sijiang Hu,Yahao Li,Hongqiang Wang,Qingyu Li,Fenghua Zheng
Iron sulfides have shown great potential as anode materials for sodium-ion batteries (SIBs) because of their high sodium storage capacity and low cost. Nevertheless, iron sulfides generally exhibit unsatisfied electrochemical performance induced by sluggish electron/ion transfer and severe pulverization upon the sodiation/desodiation process. Herein, we constructed a yolk-shell FeS@NC nanosphere with an N-doped carbon shell and FeS particle core via a simple hydrothermal method, followed by in-situ polymerization and vulcanization. The FeS particles intimately coupled with N-doped carbon can accelerate the electron transfer, avoid severe volume expansion, and maintain structural stability upon repeated sodiation/desodiation process. Furthermore, the small particle size of FeS can shorten ion-diffusion distance and facilitate ion transportation. Therefore, the FeS@NC nanosphere shows excellent cycling performance and superior rate capability that it can deliver a high capacity of 520.1 mAh g −1 over 800 cycles at 2.0 A g −1 and a remarkable capacity of 625.9 mAh g −1 at 10.0 A g −1 .
✓ 已验证
产品关联
DOI
PubMed
高影响因子
INDUSTRIAL CROPS AND PRODUCTS
·
2025
·
IF 6.2
Qiaoguang Li,Wei Wei,Wenqing Xiao,Yunliang Li,Zekun Chen,Guijun Xie,Yigang Wang
We have successfully developed a molecular design strategy to synthesize a hydrogenated rosin-modified isocyanatopropyltriethoxysilane crosslinking agent (HRIS) with organic and inorganic active groups. Then curing it, rosin-based silicone rubber chemically cross-linked modified pine (RSP) is formed. This process enables the organic integration of fire-retardant silicon, nitrogen elements, and the rigid hydrogenated phenanthrene ring structure of rosin with the internal and external surfaces of the pine’s porous structure through chemical bonding. In the channels, rosin-based silicone rubber with 48.81 % of carbon, 42.96 % of oxygen, and 8.23 % of silicon, respectively was observed. The degradation mechanism coupled with LOI (limiting oxygen index) testing revealed that the RSP exhibited enhanced flame retardancy, with its LOI significantly increasing from 24.68 % to 25.4 %. Additionally, it exhibited higher thermal stability up to 330℃ than pine, indicating that the fire-retardant performance of RSP was effectively enhanced through the crosslinking modification with HRIS and PDMS (hydroxyl-terminated polydimethylsiloxane). During the thermal degradation process, RSP will produce gaseous cyclic siloxane molecules such as D3 (hexamethylcyclotrisiloxane), D4 (octamethylcyclotetrasiloxane), D5 (decamethylcyclopentasiloxane), etc. This study demonstrated that a new type of adhesive has been synthesized, but the influence of byproducts on the entire system should be considered in application, which is of significance for indicating the direction.
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）